Pcer020924.1
Basic Information
- Insect
- Polydrusus cervinus
- Gene Symbol
- -
- Assembly
- GCA_935413225.1
- Location
- CAKXYS010000500.1:109876-120272[+]
Transcription Factor Domain
- TF Family
- MBD
- Domain
- MBD domain
- PFAM
- PF01429
- TF Group
- Unclassified Structure
- Description
- The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 1 9.1e-16 1e-11 45.6 0.2 8 72 237 298 232 300 0.86
Sequence Information
- Coding Sequence
- ATGGAAAACAAAGATTCTCCAAGTGAAAGTGTAGAGCCTGAAAGCATTGCAAGTACAGAAACAGCGGACGAACCCGTAGAAGTCAAGAAAAGTGAAgaagtaaaaaaagttttggagGAAGAATCCATTAAACCTGACGCCACTGAAAGCAGTGAAAATAAGCCAGCACAAAATGGTGTAAGCGAAACAGAAACGGCGGAAAACTTAGAGGAAACTGATAAGACCATAAACCCCATAGAGGAAAATGTTACAGAATCCATCGATAAGCCTGGAAGGACAACACGAGGTACAAAGCGAAAAGCCAATGAGGCTGAAAAAAATGACACTTCAACTGAAAATGTGGAAAGTGAGACTGTAGAGCAAAAAGAAAATGTGGATTCAAAGAATGATGAAAATGTACAAAAAGATGATCAGTCACCagaAGATACAAGTTTAAAATCTATCCCAGAATCCTTACCGCACATAATGGGTAAAGGAAAACGGGCTCGAATTCCCAACAAAAGATATAGTGATATTTTGTTATCACCTAACCGAAAATCTATGGGTCCCTCGAAATCAGGCAGTGTGGGAGATTCTGATgaaatttctataaaagaagaACCAGCGGAGTCACCTGTTGTCAGTGCTGTTACAGTGAGCAGTCCTAGCTTGCCTTCAAAGAAATTGCGTGCAGTAGCACCAAAAGAAAACTTACAGGATCCGAAATATTTAAAACCGTTCAAGTACGGTTGGAAACGAGAACTTGTCTGGCGATCTACTAGTACCGCCAGTAAGCCCGCTGGCGACATATACTATTATACCCCGAGTGGCAAAAAAGTCAGATCATTCAGGGAGGTATCTGATCACCTTACTAACAAGAACCTTATGCTTGATAACTTTTCATTCACCAAAGAACCGCTAGGCATAGACGATCCTGAGAAGGAAATTATAAGAGACGCGAAAATAAAGTCGTCTGAGAGCTTTTCTGACAGCCCTGCTCCAAAGAAGGTAGTGGAGATTAAGAAACCAAAGAAGGTGGTGCTTAGTCCTAAGAGCGATAGTCCTAAAGTAGTTCCGAAGGTTGATGTGACTCCTAGTAAGAGAAAAGTGGAACCTCCTCCGCCAAAAGAGACTCCGCCAAGTGTTAGTAAAAAGATAGTTAAAATGCCTCTGAGAAAAAGCAAGACGCCGGTGGCTAAAAAGCCGAAGTTAGCACCTAAAAATGAAGAACCTCCAGCCAAGGTGGCCACTCCCCCTCCACCTATAACGAGGTCAAGTCCCAATAAAGTTACTAGcaAGCCCTGTCAGCCATGTTCAATAAGATGCGACGGACTTCAAGGGGTTGTGCCGACTTTGCAGTGTCGACTCTGCCTGTGCCTCTATCACCACGAATGTGTCGGAATGAGTCCGAGCTTGAACTTTCCTTATGTTTGCAAGAACTGCCATGAGCAAGGCCAATCGACCAACCAATCGCCAGCTACAATCGTCGCTCCTCCCCCTCTAACTCCCATCAATACTCTTAAATCCGTTTCAACCTCCCATTCTACCACGTTACCAAAGCTTCAACGCATCCCGAGACCCGATTCTTCTGATCCGGTTCCGATTTTACAACCCCTTCAAGCGTTACCTCCCTTATTAGAAGTTCCTAAAGCTACCACTGTTGAAGAAACTGTTGCCCCAGTGAGGACTGAGATGCCTAAATTAACCCCCAAGCCTGCTCAAATTCAGCAGGAAGCGGTCATGGAGGGGGCCAAGTCGCTGGTAGGGTCTGTGACCTCTTGGTTGCCCCATAATGTGAAGATTGTGAACAGTGAGGAGCCTACTGAGGCGCCTAGGCCTCAGTATGTCGAGTACTTGGGCGGGAGAAAGTTCTTAGTCATACCGAAGCACAATTTCATGTCAGTGTCTTCTAGTCATATGACGACACGTTCCGAGGAGTCAATTGTTACTCCTACTGCCCTCCAACCCACCGAAGTTCCTATGGCTTCGGCTAGCTTAGGTCCTAGTAGTAGTTCTAACTCCAACGATACTTTAAACACTCAAAGCACCTCCATAAATACTCAAAATGTCTCCCAAGAACCAGAAAAGGTCCCTGCTGCTTCTGAACCAACTGAATCTGCTCCCGAGATAAAAGAAGAACCACTTTCGCCCGCTAAAGCTGATAATAAGCAACCTGCTGAGCCTATGGAGGTTGACGTTGATCTGAAGGAGTGTGACGACGGTGTCGAGGGCTCGTTGGATGTCAAAGAAAACGACGCTGTAATAGAAGGGGAAGATGAGGCCAGCGCGCAAAATGCAgctaataaattgaaaaaacgcAACCTTAAATTGAAGAGTATAACTAATACGAACTCTACTACTCCCGAAGAGAAAAACGAGGCGAAGTTCATGGAAAACTATTTACAGAATTTGTCGTTTGGCTACAACACGTTGCTTTATGTATTCCAGTATTTAAAAGTTCAAGATCTTCTTAGAGCAGgtTGTGTATGTACAATGTGGCGAGACATAGCGAGTCACCCCATCTTGTGGCGAACAGTGAGAATGAAGAATTCTCAGGTTCATAGCTTCGAGGGACTCGCTAATACTCTGAAAAAGCACGGAACTGTGCACCTGGATTTAAGGAAAATGCTCTTGCCCAGCAACGGAGATGAAATTTGGCCCGAATTTTCTCTGGCTATAGAGCGAGTTGACACATTGAAGAAAATCGAACTGTGCAGGTGTCCCGCAAGCGTTGTGGAGCAATTAGCTACATCCAACCCCACCTTAGAAATAATCAACGCAGTAACAATAAAATGTGAGAGCATAAACTTAGACCCTCTAAAGtccttaataaaaatcaaagaatTACGATTAAAGTCGACTTCAGGATTAAGTATAAATTCCATAGACTCTTTGAAGGAgttgaaaaccctaaaaatattatCCTTAACATCCGTCAATGACTTACACAAGTTAAACTTATCCGTGATAGCGGAATTGACGAATCTAGAGTCTCTTGACATAGGCGAATGTACAGAATTCCCCAAAAATTTTGGACAAGACATTTTGAGTAAGTTGGAGAAGTTGGAGAAATTGAGACTGGAAAAGGGTCAGGGAAACTGTCACACTTTCGAGATACTCGAGGCAGTGAGGGGTATGAAGAAGCTGGAACAGTTGGAGTTGGTGAATTTTGATGTTAAATCTGGGTTTGACAAGGCACTGGGGGTGTGTACGAATATAAAGAAGTTGATGATAATTCCTACTTATATTTCTCAAAGTGCCACCACAAACAATATGGTGTTAGCTGGCGTGTTAAGGTTACAAGGAAGCCTCACTCACTTTGTTTGGGGCGTAACACTCGAATTGCTCCGAGTAACCGAACTATTTGTCGATCAATGCGAGGACtccaacaaaaaagaaaaaagacccaCCGGCAATGGAGACAGTATCCCAGTACTGAAACCGGTACCGGATCTATCGCATGGCGGAGACATACAAGCAGCTAGTAATCCCCCGCAAGTAGAGATCTTACCACTTCCTAACCTACAAAAATTGCTACTGAACAGTTTACCTACGACTCGGGTGAAAATCTTGAAAATTCCGTTCCACGCTACGTGGCGGCAAACGCTGACGGATTCCGTGTAG
- Protein Sequence
- MENKDSPSESVEPESIASTETADEPVEVKKSEEVKKVLEEESIKPDATESSENKPAQNGVSETETAENLEETDKTINPIEENVTESIDKPGRTTRGTKRKANEAEKNDTSTENVESETVEQKENVDSKNDENVQKDDQSPEDTSLKSIPESLPHIMGKGKRARIPNKRYSDILLSPNRKSMGPSKSGSVGDSDEISIKEEPAESPVVSAVTVSSPSLPSKKLRAVAPKENLQDPKYLKPFKYGWKRELVWRSTSTASKPAGDIYYYTPSGKKVRSFREVSDHLTNKNLMLDNFSFTKEPLGIDDPEKEIIRDAKIKSSESFSDSPAPKKVVEIKKPKKVVLSPKSDSPKVVPKVDVTPSKRKVEPPPPKETPPSVSKKIVKMPLRKSKTPVAKKPKLAPKNEEPPAKVATPPPPITRSSPNKVTSKPCQPCSIRCDGLQGVVPTLQCRLCLCLYHHECVGMSPSLNFPYVCKNCHEQGQSTNQSPATIVAPPPLTPINTLKSVSTSHSTTLPKLQRIPRPDSSDPVPILQPLQALPPLLEVPKATTVEETVAPVRTEMPKLTPKPAQIQQEAVMEGAKSLVGSVTSWLPHNVKIVNSEEPTEAPRPQYVEYLGGRKFLVIPKHNFMSVSSSHMTTRSEESIVTPTALQPTEVPMASASLGPSSSSNSNDTLNTQSTSINTQNVSQEPEKVPAASEPTESAPEIKEEPLSPAKADNKQPAEPMEVDVDLKECDDGVEGSLDVKENDAVIEGEDEASAQNAANKLKKRNLKLKSITNTNSTTPEEKNEAKFMENYLQNLSFGYNTLLYVFQYLKVQDLLRAGCVCTMWRDIASHPILWRTVRMKNSQVHSFEGLANTLKKHGTVHLDLRKMLLPSNGDEIWPEFSLAIERVDTLKKIELCRCPASVVEQLATSNPTLEIINAVTIKCESINLDPLKSLIKIKELRLKSTSGLSINSIDSLKELKTLKILSLTSVNDLHKLNLSVIAELTNLESLDIGECTEFPKNFGQDILSKLEKLEKLRLEKGQGNCHTFEILEAVRGMKKLEQLELVNFDVKSGFDKALGVCTNIKKLMIIPTYISQSATTNNMVLAGVLRLQGSLTHFVWGVTLELLRVTELFVDQCEDSNKKEKRPTGNGDSIPVLKPVPDLSHGGDIQAASNPPQVEILPLPNLQKLLLNSLPTTRVKILKIPFHATWRQTLTDSV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01240684; iTF_00196228; iTF_00444134; iTF_01187855;
- 90% Identity
- iTF_01240684;
- 80% Identity
- -