Basic Information

Insect: Pollenia labialis
Gene Symbol: Hr39
Assembly: GCA_949318255.1
Location: OX439141.1:7225779-7231356[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.21 5.4e+03 -2.0 0.2 100 163 142 205 101 227 0.63

2 3 2 5.2e+04 -8.0 11.8 48 145 275 362 222 416 0.43

3 3 9.7e-89 2.5e-84 285.6 18.2 1 408 497 898 497 898 0.78

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.21	5.4e+03	-2.0	0.2	100	163	142	205	101	227	0.63
2	3	2	5.2e+04	-8.0	11.8	48	145	275	362	222	416	0.43
3	3	9.7e-89	2.5e-84	285.6	18.2	1	408	497	898	497	898	0.78

Sequence Information

Coding Sequence: atgtcAACCATTAAAACAGAAAATGTAGCTGGCACATCAGTAGTGACCACGACTACTACAGGAGGCACTAGCTTTCAATTTCCCATTAATATGAGCAATTCAGCAGGTGGAGGATTGGGAAATGCAAGTGCAGGTATAACCACTACAACTTGTACTACCACCACTACCAGAAATAATGTTTCTGTAACAAATATTAAATGTGAAGTGGATGAGGGAGGTAATTCTTCGTCGTCTACAAATGGCAATATTGTTTCGGTGGGCTTTTATAATGGTTCTAGGGGCATAAGCGGGACAAGTGTAATAACAGCGGGTCATGGTATAAGAATACCTGTGACCAAAGCAGAGGATTCAGATTCTGAAACGGAACTGACTAATATTGAAAACTTAAAAGTGACCCGAAGAGTGGCTAGTTCATCAAGCTCCACCAACAATCATCATAATGGCCCTAGGCCCATGTCTTGGGAGGGAGAGTTATCGGAGAATGAAGATACTAGAGAAGCTGAGTTAATGGATACTGATACCAGCATGAGTAATGGTGGTCTACAGGAACCCTCCAATGCAGTGGCAGTTATAAAAAGTGAAGCAACTACTACCACTCCTTCCACAACGGGAGTGGGCGCTACTTTAATTAAAACCGATGCCGAACAATTAATGTTAGACGTTCATCATGCGGCAGCTGCAGGTTGTATTTATCATCCTAAACTCAAGTTAGCACCTACTCAAAGTGATCCCATCAATTTGAAATATGAGCCACCTGATCACTCGGCTTTAGTAAATTCACCTTTAATGGTTCGCCAAAAATCCACTACAGCTTTGCCTCATTTACCTGCCAATCCCAGTCCAGATTCTGCCATACATTCCGTTTACACGCACAGCTCACCCTCCCAATCTCCTTTGACATCACGGCATGCTCCTTACACTCCTTCCCTCTCACGAAATAATAGTGATGCTTCTCATAGTTCTTGCTATTCCTATTCTTCGGAATTTAGTCCCACCCATTCACCTATACAAGGCAGACATCCAGCACCTCATGGGGTATATGGTAGTTTTAATGGAGCAACGGCCAATAGCATACAACATTCCGCTTTACTCTATAGGCCCATGATGGGTTCAGCGCCTTCGGCACAATCAGCAAAATTGGATGCGGCAGCAGGGGAGGTTCAGAATTTATCTATGGATGCCTCCTCTTCTTCAGCATCCTTTACTATGACTAGTGATTCCTCTGGCTTACCAGCTTCTCCGGCAGCTGGCATATCCCGCCAGCAATTAATTAATTCCCCTTGTCCCATATGTGGCGACAAAATATCCGGTTTTCACTATGGTATCTTTTCGTGTGAATCAtgtaaaggtttttttaaacgtACCGTCCAAAATCGTAAGAATTATGTTTGCGTACGGGGAGGACCCTGTGCGGTAAGCATTACTACTCGTAAAAAATGTCCAGCCTGTCGATTTGATAAGTGCCTGCAGAAAGGCATGAAATTGGAAGCAATACGAGAAGATCGCACTCGTGGAGGCCGTTCTACTTATCAATGCTCTTATACTCTGCCTAATTCAATAATGAGTCCTCTGCTGTCCCCcgaacagcaacaacaacaaaacccaACACAAAACCTAATAGCCGGTCAACAACATTCACAATTACAACATCAGCTACAACAAAGGTTGAATCCCCCCCTACAATCTCCTCATCAATCAAATGGTTACGGTTCACAAAACTCTAATTCCTCAACTGCAACCACTTCTACAATTAAAACCGAACAAACAGATCCTTATTCAAAAAATCTGCCTTCAGCTCATTCACCTTCATTAAATGGTTTGAATTCTTCATCGCGTTCACATTCTCATATTGCTAATAATACTTCCTCCTGCTCCTCTGCCTCTTTAAATTCTGTGCATCACAACAGTATTCCCCAACTTTTGCAAGAAATTATGGATGTGGAACACCTTTGGCAATATACAGATGCCGAACTGGCACGCCTAAATCAACCGTTGACCTCTTCGCCCAGTTCGGCTTCACTTAATTCAAATTCGACGGATTCTTCTGCTGCTGCCAATCAAATGACCAATCCACTGCTGGCCAGTGCTGGTCTTTCGTCTAGCACCAATCCCGATTTGATCGCACATCTGTGTAAGGTGGCCGATCATCGTTTGTACAAGATTGTAAAGTGGTGCAAGAGTTTACCCTTATTTAAGAACATATCGattgaCGATCAAATTTGCCTACTTATCAACTCGTGGTGTGAACTTTTACTTTTCTCCTGCTGCTATCGTTCTATCGATACACCGGGAGaaattaaaatgtctttggGTAAAACAATAACACTTCCACAGGCTAAACTTACTGGTTTTCAGCCCTGCATTGAACGAATGCTGAATCTGACAGATCATTTAAGACGTTTACGTGTTGATCGTTATGAGTATGTTGCTATGAAAGTCATTGTGCTGCTGCAATCAGacacTTCGGAATTACAAGAACCCGTTAAGGTTAGAGAGTGCCAGGAGAAGGCTTTGCAAAGTTTACAGGCGTACACATTGGCCCGCTATCCCGATTGTCCATCGAAATTTGGTGAATTATTGCTGCGCATACCCGATCTACAGCGAACGTGCCAgttgGGCAAAGAAATGCTGTCTATTAAATCCCGTGACGGtggtgattttaatttattaatggaACTTTTAAGAGGAGAACATTGA
Protein Sequence: MSTIKTENVAGTSVVTTTTTGGTSFQFPINMSNSAGGGLGNASAGITTTTCTTTTTRNNVSVTNIKCEVDEGGNSSSSTNGNIVSVGFYNGSRGISGTSVITAGHGIRIPVTKAEDSDSETELTNIENLKVTRRVASSSSSTNNHHNGPRPMSWEGELSENEDTREAELMDTDTSMSNGGLQEPSNAVAVIKSEATTTTPSTTGVGATLIKTDAEQLMLDVHHAAAAGCIYHPKLKLAPTQSDPINLKYEPPDHSALVNSPLMVRQKSTTALPHLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQGRHPAPHGVYGSFNGATANSIQHSALLYRPMMGSAPSAQSAKLDAAAGEVQNLSMDASSSSASFTMTSDSSGLPASPAAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCAVSITTRKKCPACRFDKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSIMSPLLSPEQQQQQNPTQNLIAGQQHSQLQHQLQQRLNPPLQSPHQSNGYGSQNSNSSTATTSTIKTEQTDPYSKNLPSAHSPSLNGLNSSSRSHSHIANNTSSCSSASLNSVHHNSIPQLLQEIMDVEHLWQYTDAELARLNQPLTSSPSSASLNSNSTDSSAAANQMTNPLLASAGLSSSTNPDLIAHLCKVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCYRSIDTPGEIKMSLGKTITLPQAKLTGFQPCIERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTSELQEPVKVRECQEKALQSLQAYTLARYPDCPSKFGELLLRIPDLQRTCQLGKEMLSIKSRDGGDFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01259264;
90% Identity: iTF_00045401;
80% Identity: iTF_01237737;