Basic Information

Gene Symbol
RREB1
Assembly
GCA_010416935.1
Location
QUOI01000004.1:10621432-10627934[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.033 2.6 8.4 0.3 1 23 47 69 47 69 0.96
2 16 0.00038 0.03 14.5 0.3 1 23 83 105 83 105 0.97
3 16 1.6e-06 0.00013 22.0 0.8 1 23 111 134 111 134 0.97
4 16 0.067 5.3 7.4 0.1 1 23 230 254 230 254 0.93
5 16 0.76 60 4.1 3.1 2 23 260 282 259 282 0.93
6 16 1.8 1.4e+02 2.9 2.6 1 20 338 357 338 359 0.85
7 16 0.39 31 5.0 0.2 1 23 474 496 474 496 0.96
8 16 2.2e-05 0.0017 18.4 0.3 1 23 505 527 505 527 0.98
9 16 0.00096 0.076 13.2 2.8 1 23 533 556 533 556 0.97
10 16 0.001 0.081 13.1 2.7 1 23 952 975 952 975 0.96
11 16 0.00013 0.01 16.0 0.1 2 23 1259 1280 1258 1280 0.97
12 16 6.4 5.1e+02 1.2 4.7 1 23 1286 1309 1286 1309 0.95
13 16 0.0032 0.25 11.6 2.2 1 23 1346 1370 1346 1370 0.97
14 16 0.8 63 4.0 6.9 1 23 1458 1481 1458 1481 0.96
15 16 0.016 1.3 9.4 0.3 2 23 1534 1555 1533 1555 0.92
16 16 0.013 1 9.7 5.1 1 23 1561 1583 1561 1583 0.98

Sequence Information

Coding Sequence
ATGATATTTGATTTGTATGaaaTGACTGTAAAAAGCGAGCCAGATCCAGAACAAGAACAGGAACACGAAGAGGAACAGGTTGAGATACAGGCGGATGCAGCATCTCCTACTTCtagtATCGATTTACCCGAAAATACACACCCGTGTCCAGCTTGTCCGTCAATACTTCCGACATCTCACGATCTGACGAATCATCTGCGCGAGCATAATTCACCAAGGAGTACAGATTACGGCGGAGAAGAGGATTACTGTTGTGCTATTTGCCAAAAAGTCTTGAGTTCGGCAAGTTCATTGGACCGTCATGTACTCGTACATTCGCGTGAAAGACCATTCAAGTGTAAATATTGTGACATAGCTTTCACAACCAATGGTAATATGAACAGACATGTTAAAAGTGCTCATCGCGGTGAAAGATCACCTCCGCAGAGTTACACCGAGTCAGAAAGTACGAGCAACGATTCGATAAACTCGTCTAGAAGGCAACCATTAGAAgaacacaacaacaacgaaaTATCGAAACGTACATCGCCAAATTTCTTGATTAGAGAAAGATTAGCTAAGAATTTAACGAACAAACGTAAATCCCCGTCGTTCACCAGGGAAGATGAAAATCCAAGAAAGCACAAGATTTTGTTGAACAATTCGAGGACAGAGATCAAACGTACGCCCACGGAGACGCAAAATTCTTACAATTGTCCGGTATGCAATAGGCAAGACTTCGCAACGAGCGGTCTCCTGGAAACACACTTGGAACAAAATCATCCCGAATTCACGATAAGGTGCGAACCATGTAACCTATCTTTCAAAAATCATCGAGTATTAAACTTACACCGATGCATGATACACTTTTCTGACTATCCCGTTGGAATCCCTGCGAGAAATTTACGTAATTCCGTAGTAGGATTCGACGATTTAACTTTTGTTGATTTTACATCGGCTAAATTTCCAACTATTGCTAGGGCTATGTGCGAGCAAGCTATGCACCGACCGGCATCCGGAGAAGGTACCAACTTCCAGTGCAGCAAATGTTCAAGAGCATTTCCTTGTTTCAAGTCAATGAAAGAACACCAAAATGAATGTGGTAAGTGTAGGTCAAATTTGCAATGTAGACCGATAGATATTGGGGAATCCCAGAGGGATTATTTTTTCGCGGGCCTTGAATTGCACAATAAAGCGGCATTGACCGAGGCCAAAGATGGAAAGGATTTAGCGGATATAGAAAGCATTTTGTCCGTTACATCGGGTCCAATTTTACAAAACTTTCCCCGTTCGGATGCTAGTACACctgagaataatattaaatttaattcgagCGTTGGTTCTTCTGGTTCATCAGGAACGATGTCGTCCGAATATCACGAGGAAGAGGCACAGGATTTATTTGCTGCCGAATTTAGGAAGATGAAATTAAAAGGAGAATTCCCTTGCCGATTGTGCACATCGATATTTCCTAATTTGAGGGCTTTGAAAGGACATAATCGTGCTCACATGGGCGTAGGACCAGGAGTTCCATATCCTTGCAACATGTGCCCTTATACTAGTACCGATAAGGCCACTCTTGTAAGGCATTTAAGATCTCACAACGGTGATCGGCCGTACGAGTGCTCGTTATGCAATTACGCTTTTACCACTAAAGCAAACTGCGAGAGGCACGTTAGAAATCGTCATGGCAAATTAACAAGGGAAGATATCAAAAGTGTTTTGATTTATCATCCGAATGAGGACTCGACGAATGATAACATCGGTAATTCGCCTAGAGTGACGAAAGACGAGGCGAGAAAAAGTTTGATCTATCCGAACGATAGAGAAGATTCgatgcaacaacaacaacagcaacgtTATCTGCCAATTCCGATTGACTCTAAAGGTGACATTAGAGTAATAGAAGAAGCTAAATTACCTAGCCCTGAATTAACTTCTTCTATTCGCAATATGATAGTTAATCATTGCGAAAGCAATGATACTTACGGGAGATCGAGCATACCAGGTTCCGGTCTTATTTCAAGAACCATGGAAGAAGCTACCACGTCTCAAGATCAAAGTGGTAGAGCTGATGATGATCTTGAATCAAGGTCATCCAATGAAAGCGTGCCTCTAGTCATTAATAACGAATCAGATATGCACCAAAGAATGCAAGCTAGTCCGattaatttgaagaaaatgtCTAACCCATCTAACACCGGAAATTCAAATCAGGATGGACCGTTGGATCTTAGCATGGACGTTCTAGATTTGAGCAAGAAGGCTAAGGAAAGAAACGGTGCTGGATCATTGAGATCTAACGAATATCCTAACAACGATCGTAGAGAATTTTACGATTCTACCAGTCAATTATTTCTCACTCAGGCTCTTTTGCAAGCAAGTCAAAATACTTCACCGGGTACTTCGCCTAGTACCTCCCAAGGAAATTCCCAGACAAATCCTTTACAAAATTTCTACGCCAATGCtcaaataatttatcgcaATTTGGGATCGATTTCTAACCGAGTAAATGCTGGAATTTTATCATCTTACATGTTCAATTCGCAATTTTTTGGACAAGACTTAAACATCAGTGACAGAATTCAAAAGGAATTCGCTAGGGGCTTGCAATTAACCAGCGGTGGTACTTTAGTTGATCCATcgggaaataataatttcccgGCATTTCCACAAGCCAACGATGCCCCGTCGCAAATGGTAACCGATCAAAATGATTATACCAGTTTGCTCGGTACGAAGATGACCAATAAGACTATATCACCTCGCGAAAAGATTGATAATTCGGCTTCAACGAATTCGGTTAAAATGATCATCAAGAATGGCGTATTAATGCCTAAACAAAAACAACGAAGATATCGTACCGAACGACCATTCTCTTGCGGACACTGTTCCGCTAAATTCACATTACGAAGTAACATGGAGAGACACATAAAACAACAGCATCCCGAATTTTGGAGTCAACGACCACGGGGTGGTCATTCAACTAGAGGTAGACCACCAGCAAATcatcaaaatataatgaaaaattctgGACAGTCAAACTCACAATCATCATCCCAATCTTATTCCAGTATACTCCCCAAAGCTGATCCATCTGCAACGACAGTAGAATCAACCGGTAGACATTCGATTTCAGAACAAGTGAAATATGCTATTCTGGCGCAACAATTGAAGGCTAACAAAATGGACGATAACGATACCGACGAAGAATTGATCATCGATGAAGATCCAGTTGATAAGGAGATGCAAGAATCTCAGGAACAAACTGAACAACGTTCGACGAGTTTGTTGAGAGGACAATTGGAAGGTAACGAATCTAACAAGGATATCGTCGTGAAggaagaaatattagaaagagATTCATCCGACGTATTTAATAACGAACAATCTAAGGAACATAACAATACCAATGAAAACGGCCAAAGTTCTGGTAACGAACATGCACTCGATGATAAAACGGAAGAGACTACTTTGGATGCTAATTCGAGACACGCATTCAAAATGGATAATTGCAATGATACCATTCAAGATAGACAAGAGGATAATACTGCTGATCTTGCTAGCGTATCGGAATTATTGGACAACGCTTCTCATCAGTATCAACACTTTCAACCGCAATATCTGAGCGACGAGGAAGGTTTAGTCGCGTCTACGAGCGATTTCAATAATTCCGGAAGCGAGGATAAATCTGACTCAGTTAATTCCGGAAATTCTAACAACGcttcttcgaaaaaaaagaagaaaaagaaaaagaagaagaaatcggCTTATTCTTTAGCACCCAACAGAGTAATGTGTCCCTATTGCGATCGTCCATTTCCATGGACGTCATCTCTCAGAAGACACATTCTTACACATACCGGACAAAAAccatttaaatgtatatactgTTCACTTTTGTTCACCACCAAATCTAATTGCGATAGACACCTATTGAGAAAGCACAAAACTAATCCGTACAAGATAAGAAGAGCTAGAAATTCGTCATCGCCTGACAGTCAAGTTGTCAATACgaataatacattttctatGCGAAATGTTCCCGAAAGGCCGTACAAATGTAATCAATGTCCGAGTTCAACGTTCTCAACGTTAGGAAACTTGAAGAAACATCGTTCGACCAAACACTcgcgtaaaaataaattgagatCCGTTTCGCCGTCAACCGAGACGCAAAATAGTCCACTACCATCATCTAAACAAAATGATCTTAGCGATTACGAGAGCCGATCCTCAAGCGTGTCAGAGAATACGGAACAACAACAGGTATCACCGTCCGAAactcaaaaacaaaattcaaataattctaacGCATCGTTATCCAATACCGAATTGTCGCGATCACGAAGAACTTCACCGAGATCATCACCCGGTCCTAACGATGTACCATTCAAGTGTCATCTTTGTGATTGCGGATTTGCCGATCGTCACGATTGTTTGGAACACATCAAGATCAATCATAATGAATCTTACGAGATGCTCGTAGCAAAGGGTGCTATGGATATGGATATTGACGGGCTGGAAGATCATCaagtaccaccaccaccacctcagCAACATCTTAGCGATggggaggaaagaaaaggccGATTTCCAGATTACAGTAATagaaaaGTAGTCTGCGCCTTTTGTATAAGAAGATTTTGGTCAGCTGAAGATCTTCGTCGTCATATGAGAACGCATACAGGGGAAAGGCCATTCTCGTGTGACATTTGTCTTCGTAGATTCACATTGAAACATAGCATGCTGCGTCATCGTAAAAAACACGAATCAGTCGATTCAACGATGTACGTTGGTACCAGCGGTGACGAAGAAAATTCACCTACTCAACCACCTACGATAACACCCCGTACACAAAAGCAACCACCAGTTTTAATGGCCACCAATATCAATAATTCGAGAATTCAAGATAGAATCTCGTTGTCTGTTGCAACCGGTGATGCCGCGCCAGGAGGTGGTTTTATGAGATACAACAGTTACGAAAAATTAACAACATTTGCCGGGAAACTTACCGCAAATAACGCTCAGCTtcataataatgcaataaataatgaattatccGAAAATACTGACAACGATTTGATCTCGAATCTTTTAGGAATACGCGACAAAAGTTTTATCGATAGAGTTCTTCAAGCATCACCCGACGATGCTGCTAAATTGTTAGGCGTACAACGTAGTCACGAATGA
Protein Sequence
MIFDLYEMTVKSEPDPEQEQEHEEEQVEIQADAASPTSSIDLPENTHPCPACPSILPTSHDLTNHLREHNSPRSTDYGGEEDYCCAICQKVLSSASSLDRHVLVHSRERPFKCKYCDIAFTTNGNMNRHVKSAHRGERSPPQSYTESESTSNDSINSSRRQPLEEHNNNEISKRTSPNFLIRERLAKNLTNKRKSPSFTREDENPRKHKILLNNSRTEIKRTPTETQNSYNCPVCNRQDFATSGLLETHLEQNHPEFTIRCEPCNLSFKNHRVLNLHRCMIHFSDYPVGIPARNLRNSVVGFDDLTFVDFTSAKFPTIARAMCEQAMHRPASGEGTNFQCSKCSRAFPCFKSMKEHQNECGKCRSNLQCRPIDIGESQRDYFFAGLELHNKAALTEAKDGKDLADIESILSVTSGPILQNFPRSDASTPENNIKFNSSVGSSGSSGTMSSEYHEEEAQDLFAAEFRKMKLKGEFPCRLCTSIFPNLRALKGHNRAHMGVGPGVPYPCNMCPYTSTDKATLVRHLRSHNGDRPYECSLCNYAFTTKANCERHVRNRHGKLTREDIKSVLIYHPNEDSTNDNIGNSPRVTKDEARKSLIYPNDREDSMQQQQQQRYLPIPIDSKGDIRVIEEAKLPSPELTSSIRNMIVNHCESNDTYGRSSIPGSGLISRTMEEATTSQDQSGRADDDLESRSSNESVPLVINNESDMHQRMQASPINLKKMSNPSNTGNSNQDGPLDLSMDVLDLSKKAKERNGAGSLRSNEYPNNDRREFYDSTSQLFLTQALLQASQNTSPGTSPSTSQGNSQTNPLQNFYANAQIIYRNLGSISNRVNAGILSSYMFNSQFFGQDLNISDRIQKEFARGLQLTSGGTLVDPSGNNNFPAFPQANDAPSQMVTDQNDYTSLLGTKMTNKTISPREKIDNSASTNSVKMIIKNGVLMPKQKQRRYRTERPFSCGHCSAKFTLRSNMERHIKQQHPEFWSQRPRGGHSTRGRPPANHQNIMKNSGQSNSQSSSQSYSSILPKADPSATTVESTGRHSISEQVKYAILAQQLKANKMDDNDTDEELIIDEDPVDKEMQESQEQTEQRSTSLLRGQLEGNESNKDIVVKEEILERDSSDVFNNEQSKEHNNTNENGQSSGNEHALDDKTEETTLDANSRHAFKMDNCNDTIQDRQEDNTADLASVSELLDNASHQYQHFQPQYLSDEEGLVASTSDFNNSGSEDKSDSVNSGNSNNASSKKKKKKKKKKKSAYSLAPNRVMCPYCDRPFPWTSSLRRHILTHTGQKPFKCIYCSLLFTTKSNCDRHLLRKHKTNPYKIRRARNSSSPDSQVVNTNNTFSMRNVPERPYKCNQCPSSTFSTLGNLKKHRSTKHSRKNKLRSVSPSTETQNSPLPSSKQNDLSDYESRSSSVSENTEQQQVSPSETQKQNSNNSNASLSNTELSRSRRTSPRSSPGPNDVPFKCHLCDCGFADRHDCLEHIKINHNESYEMLVAKGAMDMDIDGLEDHQVPPPPPQQHLSDGEERKGRFPDYSNRKVVCAFCIRRFWSAEDLRRHMRTHTGERPFSCDICLRRFTLKHSMLRHRKKHESVDSTMYVGTSGDEENSPTQPPTITPRTQKQPPVLMATNINNSRIQDRISLSVATGDAAPGGGFMRYNSYEKLTTFAGKLTANNAQLHNNAINNELSENTDNDLISNLLGIRDKSFIDRVLQASPDDAAKLLGVQRSHE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01512393;
90% Identity
iTF_01233874;
80% Identity
-