Basic Information

Gene Symbol
-
Assembly
GCA_001465965.1
Location
NW:81571-86656[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 19 1 61 3.5 6.2 2 23 287 309 286 309 0.96
2 19 0.0035 0.21 11.2 3.7 1 23 372 394 372 394 0.98
3 19 0.072 4.3 7.1 0.5 1 23 443 465 443 465 0.98
4 19 0.0012 0.071 12.7 0.4 1 21 521 541 521 542 0.93
5 19 1.6 95 2.9 3.9 1 23 554 577 554 577 0.84
6 19 0.00093 0.056 13.1 2.5 1 23 582 604 582 604 0.97
7 19 9.3e-05 0.0056 16.2 0.4 1 23 648 670 648 670 0.97
8 19 0.0005 0.03 13.9 0.1 1 23 676 698 676 698 0.97
9 19 2.7e-06 0.00016 21.1 0.5 3 23 745 766 744 766 0.96
10 19 0.012 0.69 9.6 3.5 1 23 773 796 773 796 0.94
11 19 3.2e-05 0.0019 17.7 0.5 2 23 803 825 802 825 0.96
12 19 0.0069 0.41 10.3 0.1 2 23 833 854 832 854 0.94
13 19 0.0074 0.44 10.2 0.1 1 20 917 936 917 936 0.97
14 19 0.002 0.12 12.0 0.3 2 23 956 977 955 977 0.95
15 19 9.3e-05 0.0056 16.2 3.9 1 23 991 1013 991 1013 0.95
16 19 1.9e-05 0.0011 18.4 1.9 1 23 1031 1054 1031 1054 0.95
17 19 0.0082 0.49 10.1 1.8 2 23 1103 1125 1102 1125 0.94
18 19 0.0072 0.43 10.3 0.9 2 22 1152 1172 1151 1174 0.88
19 19 3.6 2.1e+02 1.8 2.2 2 23 1263 1285 1263 1285 0.92

Sequence Information

Coding Sequence
ATGCCGTCAACGATGGACGACGTTGAGCTGTTGAACGTTGATAATGTGTGCAGATTGTGTTTAACTGTGGACGAACCAAAATCTTCGATATTTCAAACGGAAGATTCACCTACTGCTGTACCATTAGTTACTAAAATACAAGCATGTCTATCACTTcagATATTGACTACAGATAAAGTATCCACATTGATATGCTCTTCTTGTATAAATAATGTGAATCAATGGTATAATTACAAAGAAGCTTGTTTTCATTCTCAAGATAAATTACAGAAATGGTTGGAAACTCATCCGCAGACGACAAATCCAGtggttgtaaatataaaagaagagcCTGTAGATATAGATTATTGCGaagataacaataaaatgtatGATTCCAACAGTGAATCAAACACTcatGTAACAACAAATCATGTAAAATCTGTGGGAGGAAAATTTGATTCGAAAATTGAAACGTCACGatcaggaggaggaggaggaggaggaggagtacaAATTGACAAGACATTTGATttagataaagataagaaagaattgAAATCTTCACAAtcgtcttcttcatcatcatcgaaGAATGAAGTCAACAACAAGGAAGAAGAATGCAAATTAGATAAACAATTTGACAGtgtattgattaaaaatgaacCAGAGGATGATGAAGATACTGATTGTACGATAGAAATAGATTCGGTCAGTGGTaccgaattattattaaatccaaTGGCAATTGCTAGCAAAGAGGAAAGAATAATGGAAGCTGATTCAACACAAAAATCAAATGCAACTACACCGAATagtagaaaaaagatgaaacgtGGTCCTCATACACATTTTCGTGGTACACGCGCGTATAAACAAAAGTGTAAACATTGTCAGATATTTCTACATTCTAAACAATCATATGTAAAACACATGGAAAGATTTCACAGTGAAGattgtgaaaataaagaagatttaattaaattgacgggggtggcggcggcggcggcggcggcggcatCTTCTGCCGATGAAGAAGAATTGATCGAAGATGTCGAAGAAGAATTGACGAGTATGGAAAATGATGCACCATTGACCGAAgtacaacaaaatataatcagccaattgaaaacattttccTGTTACGAGTGTCAACAGACTTTCAATGATAGAAAACATACACTTATTCATATTCGTCAACACATGCCAGATTTAAGACCATACACTTGTATCGCATGTTTAACACAATTTCGCGATAGATCTATGTACAAATTACATTGCAGTGCGTCATTCGAATGTGCTATGAAAATTGCATTGGTCATACCCAAGGAAGGAAACGAAAAGTATTTCACTTGTAACATGTGTTTAAGACCTATgccaaatagaaaagaattattgagTCATTTGTCTAAACATTCAGATAAACAATATGAAGAAATGATGTCACCAACGAGATCACCACCAAAATTACAACCTATGGCACCATTGTTAagtccaaaaaaagaaattttaccaAAATCACCGTCTCAAATGAGTAAAGTCATTGTTGGGCCTTACAAAAATGGTGATCCAGCTCATAATCATCCATGTAATTTGTGTGGTATGATTTACAGATACAAGCCTAATTTGTTAAGACATCATCTCATTTGCATCAGGTTATCACCGGAAGTAAGGACTTGTTACAGGTGTGTACATTGTGGTATGACATTtttggtatttaaaaaatttcataatcaTATTACTCTCGatcataagaaaaaagaattcgtTTGTTTCGATTGTAACGCCAAGTTCAAATCACCGAGTGATTACCTGACGCATCACGATAAACATCGAAAAATGGCCGCCAATCAAAATAAGGAGGTAACTGGTAATCAGATAATGTCACCACACCGTGGACAGAGTCCTTTAAAATCGTGGAGCGATAATGAGGAAGCAAGACGTAGCATTGATGGTCAACGATACGTTTGTAATCTATGCGGTCAAGATTTTACATCGAGAGCCAAATTGGCGTCGCATAAGAATCTACATCTTAAAGTGAAAATTTATTCATGTGTCATTTGTCGCAGTATGTTTAGCAGTGCTGGTGCTTTAGAAATTCATATGAAAGATCATGGCATTGAAGATCCACAAGAAAGAAGTGCCAACAGTTCTTGCGTTGAATATGATCGATTAGATAATAGACCACAAGATGTTGTTGTTGACACTGTTAACACGAGTACTGTCTCAGATACTGGTGATcgtgaaaatatatgtaacatatGTGGAAAGATATTCTCCAATTATCCTAATTTGAGAAgacattttagaaatattcataACGATGAAAAATCACGTTACACTTGTATACGTTGTTCGGTAccatttaaaacaaaagagcATTATGAGCATCATATGAAAATTGAACACAAAACAAAAGTCATGTTGATGTGTAGCCAATGTCCTAAGACATTTAGTTTCAAAGCTAATTTGGATCTACATTATAGGAGTGCTCATGGTGATAAACCTGGTAATCAAGAATGCGATATATGTGGTAAAGTCTTTTTGGAAGAAGCGTCCTTGAAGATTCATCGAAGTTGGCACAATCGAGCTAATTCACGTTTCTACACTCGATCATTTTTAACCAATGAGATCAAGCCAACGGTAACACCAATTTCTCCTACCgaaatgaatgataataatttagttgGTGGTTCGTCGCCTGTACGTCCAGCTAGGGCAAGAAAATCATTTCCAAATCCACCGCCTACAAAGCCACTAAACAACGATTACCAATGTCAGGTATGTGACAGTAAATTCGAAGATGTAGTCGAGTTGAGGAAACATTTGTGGGATGTTCATTGTGCTCGTAATAAACCAGAAAAAAGTTTCTCAGTTGATGAACTTCAATGTCAGTTATGTACCAATATTTTTCCAGATCAAAAAAGTCTAAAGTTACATATGGATTGGCACAAAGCCAATCCAATATTGAGCGATATACAAAAGCAAAGTTTCCTTTGCGAGATATGTAACAAACATTACAGCTCGAAGAAAGCATTGACGAAACATAGAAAACTTCACAAAGCAAATACTACGATTAAATTTCAATCGCTTAGTAGAAAGAGTGCACAATATCTCTGTAACATCTGTCGAAAGATCTTCAGCAGTAATCAATCATTGCAACGACATAGAATGTCTTTTCACAATGATTTACAATCTCCTAGGTCTCAATCATTTAGTAGCAGACGAGTGTCCAACGatgaatacaaatataaaaaaatagacgttgaaataagagaaaacacTTCAAAAGTGTTCACATCAAATGTCAGTAGTAAGAAACCAGTAACGTGTCATTCATGTAAAAAAACATTCCCAGATATGAGTGTTTTATACAAACACAAACAATTGATTCATAAACCGAGATTAACGAAAATGGCCGGTAAAACTCCAATAAAAGAATGTATTCCAGTACAAAATGCTGACGGTAGACTATCCTGCAATATATGCGATAAACAATTTTGGTCAATGTCAAATTTGAAACAACACTTTACTGCGAAACATAGAAATCATACAAAAAGTCGTTGTACAACAGCTAGCTGTAATCCGTCATATTCGACTATATCGCAGTCAATAAAAACTGAACCTTCGCCACACAAAGCAACGATTATCTGTTGTAAACTTTGCAACCGTCACGTTTGGAGTAGAGAAGAGATAGCCATACATATACTATCTGTACATGGTACACCATATGAACCAGATAACAACACTAATTTTCATAGGGAAACTGATCTTACCACTTACGTTGTTGAAGGAGCAGTTAATGCAACTTGTCCTTGTTGTAATATCAAGTATCCTAATAATAGAGCCATGAAGATTCATTACTTTAAATTTCACGAAGCTTCGGACtaa
Protein Sequence
MPSTMDDVELLNVDNVCRLCLTVDEPKSSIFQTEDSPTAVPLVTKIQACLSLQILTTDKVSTLICSSCINNVNQWYNYKEACFHSQDKLQKWLETHPQTTNPVVVNIKEEPVDIDYCEDNNKMYDSNSESNTHVTTNHVKSVGGKFDSKIETSRSGGGGGGGGVQIDKTFDLDKDKKELKSSQSSSSSSSKNEVNNKEEECKLDKQFDSVLIKNEPEDDEDTDCTIEIDSVSGTELLLNPMAIASKEERIMEADSTQKSNATTPNSRKKMKRGPHTHFRGTRAYKQKCKHCQIFLHSKQSYVKHMERFHSEDCENKEDLIKLTGVAAAAAAAASSADEEELIEDVEEELTSMENDAPLTEVQQNIISQLKTFSCYECQQTFNDRKHTLIHIRQHMPDLRPYTCIACLTQFRDRSMYKLHCSASFECAMKIALVIPKEGNEKYFTCNMCLRPMPNRKELLSHLSKHSDKQYEEMMSPTRSPPKLQPMAPLLSPKKEILPKSPSQMSKVIVGPYKNGDPAHNHPCNLCGMIYRYKPNLLRHHLICIRLSPEVRTCYRCVHCGMTFLVFKKFHNHITLDHKKKEFVCFDCNAKFKSPSDYLTHHDKHRKMAANQNKEVTGNQIMSPHRGQSPLKSWSDNEEARRSIDGQRYVCNLCGQDFTSRAKLASHKNLHLKVKIYSCVICRSMFSSAGALEIHMKDHGIEDPQERSANSSCVEYDRLDNRPQDVVVDTVNTSTVSDTGDRENICNICGKIFSNYPNLRRHFRNIHNDEKSRYTCIRCSVPFKTKEHYEHHMKIEHKTKVMLMCSQCPKTFSFKANLDLHYRSAHGDKPGNQECDICGKVFLEEASLKIHRSWHNRANSRFYTRSFLTNEIKPTVTPISPTEMNDNNLVGGSSPVRPARARKSFPNPPPTKPLNNDYQCQVCDSKFEDVVELRKHLWDVHCARNKPEKSFSVDELQCQLCTNIFPDQKSLKLHMDWHKANPILSDIQKQSFLCEICNKHYSSKKALTKHRKLHKANTTIKFQSLSRKSAQYLCNICRKIFSSNQSLQRHRMSFHNDLQSPRSQSFSSRRVSNDEYKYKKIDVEIRENTSKVFTSNVSSKKPVTCHSCKKTFPDMSVLYKHKQLIHKPRLTKMAGKTPIKECIPVQNADGRLSCNICDKQFWSMSNLKQHFTAKHRNHTKSRCTTASCNPSYSTISQSIKTEPSPHKATIICCKLCNRHVWSREEIAIHILSVHGTPYEPDNNTNFHRETDLTTYVVEGAVNATCPCCNIKYPNNRAMKIHYFKFHEASD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01233839;
90% Identity
-
80% Identity
-