Basic Information

Insect: Polistes dominula
Gene Symbol: Epn2
Assembly: GCA_001465965.1
Location: NW:290960-304533[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 3e-05 0.0018 17.8 1.4 2 23 371 392 370 392 0.97

2 11 0.035 2.1 8.1 5.1 1 23 400 423 400 424 0.96

3 11 0.0008 0.048 13.3 2.8 1 23 470 492 470 492 0.97

4 11 1.8e-06 0.00011 21.6 2.0 2 23 553 574 553 574 0.98

5 11 0.00012 0.0072 15.8 2.3 1 23 579 602 579 602 0.95

6 11 2.4e-05 0.0014 18.1 0.4 1 23 641 663 641 663 0.98

7 11 1.1e-06 6.8e-05 22.2 0.9 1 23 673 695 673 695 0.96

8 11 2.3e-06 0.00014 21.2 0.9 1 23 701 723 701 723 0.99

9 11 6.8e-06 0.00041 19.8 0.3 1 23 729 751 729 751 0.98

10 11 0.00012 0.0073 15.8 4.6 1 23 757 779 757 779 0.98

11 11 0.0006 0.036 13.7 0.3 1 21 785 805 785 806 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	3e-05	0.0018	17.8	1.4	2	23	371	392	370	392	0.97
2	11	0.035	2.1	8.1	5.1	1	23	400	423	400	424	0.96
3	11	0.0008	0.048	13.3	2.8	1	23	470	492	470	492	0.97
4	11	1.8e-06	0.00011	21.6	2.0	2	23	553	574	553	574	0.98
5	11	0.00012	0.0072	15.8	2.3	1	23	579	602	579	602	0.95
6	11	2.4e-05	0.0014	18.1	0.4	1	23	641	663	641	663	0.98
7	11	1.1e-06	6.8e-05	22.2	0.9	1	23	673	695	673	695	0.96
8	11	2.3e-06	0.00014	21.2	0.9	1	23	701	723	701	723	0.99
9	11	6.8e-06	0.00041	19.8	0.3	1	23	729	751	729	751	0.98
10	11	0.00012	0.0073	15.8	4.6	1	23	757	779	757	779	0.98
11	11	0.0006	0.036	13.7	0.3	1	21	785	805	785	806	0.94

Sequence Information

Coding Sequence: atgttaaaaaattgcTCAATAACAGCATTTGTTTCATGCTTCGATGTATACGATTTGAAACTTCAAGTTAGTAATTTGTGTTTCATTGTATATCGaactttatttcttattaacgaATGGTGCTGGACAAGGATTTTACGCCGCAGCAGTGTTTTGTTCGAAGAAATGGAATTGTCAGATGATGGGAgagatattaaaaactttgaaGACGCACGAATTAATGTAAACGAAGATTGTCGTATCTGTTTACAAAAGTCCAACGAAGTATGTCAACTGTTTCCAAACAGCAAaggtttttctcaaaaactaaTGGCAATTGCTGGTGTGCAGgtaGAAGAAGGAGATGGATTGCCATCGGTAATATGTTTCGATTGTTCTCAACTTCTTGACATATCCTACAATTTTCAAAGTCAAATACAAAAGACAGATACAAAATTACGTGAAATATTGAAACTTGGATCATGTACAACAAAAGAtactaaaaatgaattaaaagttGAAGATCATTTTTCTGATATCATAGCAGATGCgatattacaaagaaaaattacaaataatcttGACAATGATAATAAAGATGGTGAGGATGATCATAGTGGTAATAATGAGTGCAGTAGTAATATCCATGAGTCATCTATAGAAATTGatgtaaaaaattttactAATAATGAACATGACTTCTCTTccgaaataattaatgataatatagaTTCCAATGACAAGTGCAATTCTGTAATTGaactagaaaataaacaagaactATACAAAGTTGtagaagatataaaattacCTAAAAATTGTGAAAACATTACAGATAAGTTAAATAGTGTAACATGTCATACATCTAATTTAATAACAGAAATAACATgtattaaagaagaaatatcttGTGAAGAAACTGTATCAGAAAGTAATAAATCCATCGACCAAAGTACTGTAAGACAAGAACAAATAttccaacttgaaagaaaaaatgaattagaaaaGTTAAACTATAATACGCTTATGAAAAGTTCatccaaaattattaatattcaagaagaaagaaaatctacCTATAATTGTAGTGATGATGAGGAAAAACCTTTAATAAGCAGAACTACAAGACAAAAATGTACGCAATGCGTTAAATCTTTTAGTACACGTTTAGCTTTACAAAGACACATGACAGTACATAAACATAAAGCAGAATTACgttatgtttgttatatatgtgataaacaattttcaagtattactaaattaaaatgtCACATTAATAGTAGACATCATGATGtacgttttaataataagaaaaaagagagagaaaatagtgACAATAAGGATGTACATTTAAAAGCAAGGGATcttgataataattgtaataattctaTGGATAATACTaaaacggaaaaaaaaaattataaatttatatgtaaagtTTGTTCCAAACAATTTACATATCAAAAATCTTTTTTGACACACGCTAAAAGTCATCCAGAATACAATCCTGaagatttaaatgatttttctagTGAAACTGGTACCCAGTTGaatgaaatcaaaaataaatctgtacaaaaacaaaatgaatcaGACGATGGAAATAATGACGATATTGATGACATTGATAACGATGATgacaatgataatgataatttacCTATGGAAAGTCCTCAGTGTACACAATGTGGAAAATTATTTGCAACTAAAAGAAATCTTAAAAGGCATATTTCTACTCACAGTGGTTTAAAACACAATTGCTCGACTTGTGGAAAAGTCTTTTCaagaatagataaattaaaagaccACGAACAATCAAAGCATAAggaatatgaattatttggaAACTCTGAAGAAGAGAATGAAGCTGACAcagataatgaaaataaagttaatgATGGTTCTAATGAACGAAAAAAGGGTAGGCATAATAGACCACATAAATGCGCTCTCTGTCCAAAAGCATTTGCTCAACAGCAATCTTTAGCTAATCATATAGAAAGACATAAACGTACTAAAGATAGTCAAAAGCGATTTTTATGCGAAGTTTGTAGCAAATGTTTTGCACAAAGTGGTTCACTGGTTGCACATATGCGTACTCATACTGGCATTAAACCATATGTATGTAATGTCTGCGGTAGAGCTTTCACTAAAAGCACATATCTACAATTACATTCAAGAACTCATAGTGGAGAAAAGCCTTATATTTGTCAATATTGTAGTAAAGCATTTGCACGTGCCAATACTTTAGCCAGGCATATAACGATGCATACGGGAGAAGCTAAGTATCACTGCCAGATTTGTACTAAGTCTTTCAGACGATTAACGTCTTTAAatgaacacacatacacgcatacgGGTCAAAGACCATATGCATGTAAAATATGTACAAAAAGATATAACAATGCTGGTTCTTTGTATGCGCATACAAAGAAATGTAAAGCTCAGCAATTGACTAATAACTCTACAACAACTTATACTGTTGCAATGGATAATACATTACAACAAAGTAGTGGGCCCACATCACaggttttaatttattcccaaagaaaattattagagGATGCTACTGTTGGTCAAATAACACCAACTCCGCAATACATGATTGCTAATGTACATAATCAAAAAGCCTtatctacaaatattatgCAACCATTTACGGTTGAGGATTCAAATAAAGGAAGCAGTTTTATAACGGAACagtctaatttaattatcctATCAATTTTAGGGTTTTATTCTGATTTGGAGATATTGGgagttttctatatttctggACAACACGTAGTTTCATCAACACCAGCGGCGAAACTTGACATGCCAACAATGGCTATGCAAAAGaTGAGAAGACAAGGCCAGGATGTTATGCAAATGAACTTAGCAGGTATTAGACGAGATATTGTAAACCTTGCTCATAATTATAGCAGTGCACAGAAAGCCGTAAGAAAAGCTACCAGTAATGATCCTTGGGGTCCAAGTAGTACTCTTATGGCAGAAATAGCTGATTTGACATATAATGTTGTGGCCTTTACTGAAATTATGCAAATGTTATGGAAAAGACTTAATGATCATGGTAAAAATTGGAGACATGTTTACAAAGCTTTGGTACTTTTAGAGTACCTTATCAAAACTGGTACAGAAAAAGTTGCACAACAATgtaaggaaaatatttttgccattcaaacattgaaagatTTCCAACATATGGAAGGACATAAAGATCAAGGTATTAATGTACGAGAGAAAGCGAAACAATTGGTGGCCTTATTAAAAGAtgatgaaagattaaaaaatgaaagagctAGAGCATTGAAGGCCAAAGAGAGATTTGCTCAAACAGTTAGTGGTTTTGGAAGTGATGGTTTAGATACAATGTCACCTGTAAGCAGCGATTTTCAAGATTGGGAGCCTTGCAATTTGACCGAATCAGCATCACGACCTGAATTAGAAGCAGCTAGACCGCAAACAGTAGGCGAAGAAGAACTACAACTGCAACTAGCACTTGCTATGTCAAGAGAAGAAGCAGAACAAGAGGAACAACGACGGCGAAGTGATGACGTTCGACTACAATTAGCACTTAGTCAAAGCCAGCAGGACTTcaaAGCACCACAAACTGAAAAGCAAAGTCATATGCTTGATTTACTGGATGTAAATCTAGGCGAAGCAAGCAGCTCTTCTGCGCAGAATGATCCTTGGAGTATTCCAGTTACAGCTCCACCTCCAAGACCTCAgTCCTTGGATTTGTCTCAATTTCGTAAATGTAAGacTCAAAATGATCCTTGGAGTATACCAACAACAAGCAATAATTCACCTGCGATAGATCCATGGGCTCCTGTCACATCTCAAAAGCAGGCTGTTATTAATGATCCATGGAAAGCACCTACTCCATCTCCATCAGCAATAGTTACTCCTCGTTCGGCAGATCCTTGGTCGCCAGCACCAACTGCTAATGAACTTGAGGCATCCAAAAttgaagTTCGCcaggataaaataatatcttcatCTCCAACCTTCAATAATCCAACTTTAAcagaaaatattagttttacgGCGCAATCACCACAAAACATCGGTTTTAATTTACCAAATCCTACAAATGTTGCCTTTGGTACTATGAGCAACGGCTTTAAGGATCCTGGCTCTACTTTTAGCAATTTTCCTTCTCAAACTCATGGCAGTTCGGCTACAAGTCCATTGAGCGAGCTTGATGAATTTGATGTGATCAGTCAGAGGAACAAACTTGGAAGTGGTTCACAAACTACAAACAAtgggACTACATTATCTTCAGATCCATTTGATTTAGGTGGTATTGGTGAATCTTTACCTCAGAGCACTGGTGCAATTAAGAAAACACCACAATCTTTTCTTGGTGAAAATTCTGCTCTTGTAAACTTGGATAATCTTGTCAGCACTTCTACAATTAAAACAGTTACTCCAACACCAACAGTGCCCGTATCATATTCAGCGAATCCATTTGCGACAACAACAGCACCATCTCATGCTCCAACTAACCAGATTCGACAGGACCCTTGGGCTGTAAATACTAATGCTAAAGCTAATCCATTTTTATCGTAG
Protein Sequence: MLKNCSITAFVSCFDVYDLKLQVSNLCFIVYRTLFLINEWCWTRILRRSSVLFEEMELSDDGRDIKNFEDARINVNEDCRICLQKSNEVCQLFPNSKGFSQKLMAIAGVQVEEGDGLPSVICFDCSQLLDISYNFQSQIQKTDTKLREILKLGSCTTKDTKNELKVEDHFSDIIADAILQRKITNNLDNDNKDGEDDHSGNNECSSNIHESSIEIDVKNFTNNEHDFSSEIINDNIDSNDKCNSVIELENKQELYKVVEDIKLPKNCENITDKLNSVTCHTSNLITEITCIKEEISCEETVSESNKSIDQSTVRQEQIFQLERKNELEKLNYNTLMKSSSKIINIQEERKSTYNCSDDEEKPLISRTTRQKCTQCVKSFSTRLALQRHMTVHKHKAELRYVCYICDKQFSSITKLKCHINSRHHDVRFNNKKKERENSDNKDVHLKARDLDNNCNNSMDNTKTEKKNYKFICKVCSKQFTYQKSFLTHAKSHPEYNPEDLNDFSSETGTQLNEIKNKSVQKQNESDDGNNDDIDDIDNDDDNDNDNLPMESPQCTQCGKLFATKRNLKRHISTHSGLKHNCSTCGKVFSRIDKLKDHEQSKHKEYELFGNSEEENEADTDNENKVNDGSNERKKGRHNRPHKCALCPKAFAQQQSLANHIERHKRTKDSQKRFLCEVCSKCFAQSGSLVAHMRTHTGIKPYVCNVCGRAFTKSTYLQLHSRTHSGEKPYICQYCSKAFARANTLARHITMHTGEAKYHCQICTKSFRRLTSLNEHTYTHTGQRPYACKICTKRYNNAGSLYAHTKKCKAQQLTNNSTTTYTVAMDNTLQQSSGPTSQVLIYSQRKLLEDATVGQITPTPQYMIANVHNQKALSTNIMQPFTVEDSNKGSSFITEQSNLIILSILGFYSDLEILGVFYISGQHVVSSTPAAKLDMPTMAMQKMRRQGQDVMQMNLAGIRRDIVNLAHNYSSAQKAVRKATSNDPWGPSSTLMAEIADLTYNVVAFTEIMQMLWKRLNDHGKNWRHVYKALVLLEYLIKTGTEKVAQQCKENIFAIQTLKDFQHMEGHKDQGINVREKAKQLVALLKDDERLKNERARALKAKERFAQTVSGFGSDGLDTMSPVSSDFQDWEPCNLTESASRPELEAARPQTVGEEELQLQLALAMSREEAEQEEQRRRSDDVRLQLALSQSQQDFKAPQTEKQSHMLDLLDVNLGEASSSSAQNDPWSIPVTAPPPRPQSLDLSQFRKCKTQNDPWSIPTTSNNSPAIDPWAPVTSQKQAVINDPWKAPTPSPSAIVTPRSADPWSPAPTANELEASKIEVRQDKIISSSPTFNNPTLTENISFTAQSPQNIGFNLPNPTNVAFGTMSNGFKDPGSTFSNFPSQTHGSSATSPLSELDEFDVISQRNKLGSGSQTTNNGTTLSSDPFDLGGIGESLPQSTGAIKKTPQSFLGENSALVNLDNLVSTSTIKTVTPTPTVPVSYSANPFATTTAPSHAPTNQIRQDPWAVNTNAKANPFLS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01234503;
90% Identity: iTF_01234503;
80% Identity: -