Basic Information

Insect: Polia nebulosa
Gene Symbol: ZFHX3
Assembly: GCA_951329385.1
Location: OX589599.1:20030455-20039589[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.033 5.7 9.4 4.9 1 23 84 107 84 107 0.95

2 15 0.15 26 7.4 0.0 1 23 114 137 114 137 0.95

3 15 0.0032 0.54 12.6 2.5 2 22 192 212 192 215 0.91

4 15 0.27 47 6.5 0.6 1 23 227 252 227 252 0.94

5 15 0.013 2.2 10.7 1.3 1 23 270 292 270 292 0.97

6 15 0.0033 0.57 12.6 0.3 2 23 299 321 298 321 0.94

7 15 0.0007 0.12 14.7 3.9 1 23 427 451 427 451 0.92

8 15 0.011 2 10.9 0.7 1 22 471 492 471 495 0.89

9 15 0.0011 0.2 14.0 0.2 1 23 542 566 542 566 0.93

10 15 0.47 80 5.8 0.1 3 21 641 659 639 660 0.92

11 15 0.84 1.4e+02 5.0 3.5 2 19 750 767 749 772 0.91

12 15 3e-05 0.0051 19.0 2.9 1 23 1279 1301 1279 1301 0.99

13 15 0.00078 0.13 14.6 0.3 1 23 1386 1408 1386 1408 0.98

14 15 0.0073 1.3 11.5 0.4 2 23 1546 1568 1545 1568 0.97

15 15 0.33 56 6.3 1.6 2 22 1798 1818 1798 1821 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.033	5.7	9.4	4.9	1	23	84	107	84	107	0.95
2	15	0.15	26	7.4	0.0	1	23	114	137	114	137	0.95
3	15	0.0032	0.54	12.6	2.5	2	22	192	212	192	215	0.91
4	15	0.27	47	6.5	0.6	1	23	227	252	227	252	0.94
5	15	0.013	2.2	10.7	1.3	1	23	270	292	270	292	0.97
6	15	0.0033	0.57	12.6	0.3	2	23	299	321	298	321	0.94
7	15	0.0007	0.12	14.7	3.9	1	23	427	451	427	451	0.92
8	15	0.011	2	10.9	0.7	1	22	471	492	471	495	0.89
9	15	0.0011	0.2	14.0	0.2	1	23	542	566	542	566	0.93
10	15	0.47	80	5.8	0.1	3	21	641	659	639	660	0.92
11	15	0.84	1.4e+02	5.0	3.5	2	19	750	767	749	772	0.91
12	15	3e-05	0.0051	19.0	2.9	1	23	1279	1301	1279	1301	0.99
13	15	0.00078	0.13	14.6	0.3	1	23	1386	1408	1386	1408	0.98
14	15	0.0073	1.3	11.5	0.4	2	23	1546	1568	1545	1568	0.97
15	15	0.33	56	6.3	1.6	2	22	1798	1818	1798	1821	0.88

Sequence Information

Coding Sequence: ATGTGGTGTTTCCTTAGAAAAGACCCTTTGTCCATTGACAAAAAGCGTCAGAGATCGCGTTTATGCAGACAAGacACTAAGGAGCCTATCGACCAGAAGCCTGAGCTAACTCAGGAGCAAAAGATGATGAGATTTTTGGAACAACATCAGCAGCAacagcagcaacaacaacaacaacaacaacacgtGCAACAACAATCACAGCAAGGTCCAAGTGAGAGGGAGGAGGAGCGCGAGACCCCGGGACCACACACGTGTCCTTATTGTAACTTTAGTTGCTCGAATGAGTCGCGCCTACACGCACATGTCTCCTCCGTACATGGCGATCCCTCGCGACATTTCATTTGTCCTCTGTGCCAAGATGGCTTCAAGGAACGACCAGCCCTCGAACGACACGTCATGCAAATCCATTCCGTTAACTCTGAAGGACTACAGAGATTATTATTACTTGTTGACCAAAGCCATTGGCTGAACGGTGGAGCCCAATCTCAGAGAGACGAATCTCGGCAAGGTGATGATGAACGGGAGATTTCCTCGCCGCGATCAGAGGGCAGTGCTGATGGAGAAACAGAAAGATGCTCAACATGCAACCGCACTTTCAGAAACGTCGATGAGTTGTGTCAACATCAGAATGAGTCTGGCCATCTAGAACTGAAACAAACACCTCAAGGCCCAGGGTATGTCTGCTGGAAGAAAGGATGCAATCGATATTTTGATGCTGCTCATGCGCTACAAAATCATTTTAGAGAAGCGCACGCACGTAACTCCATTGCGAACATGTCAGTGTCTGAGAAACATGTCTACAAGTACCGGTGTAATCAATGTAGTCTAGCATTCAAGACGATTGAAAAACTACAGCTGCATTCACAATACCACGTTATCAGAGACGCCACTAAGTGTGTGCTGTGTGGAAGAAGCTTTAGATCAGTGTTGGCCCTTCAAAAGCACGTTGAGTCGTCCCATCCTGAATTATCTGAAGAAGAGCTAAGTGCATTCAAACGAAGCTTAGCATCGAACCCTTTACTACAAGCTGCCCAGGGCACAGCTCTAGATGCTGCAACTGCAGAGCTCCTACGCAAGGAAGCTCTAAGAACTCCTGACGATGACCTAGCAGATATGGAAGATAGAGATTCTAGCGCAACAGTCGCTGACGAGTCCGGTCATAATGACGCTGAAAACTCAGATGACTCAATTATTTACAAAGATCAACAATTCTTGGAAGATTACTTAAATTCACAAACAATGGCAGAAGACTCATATAATGACCCCAATAGAAAGTACAAATGTCATCGATGCAAGGTAGCATTTACACGCCAATCGTACTTGACATCACATAACAAAACACTTCTCCACAGAAAAGGTGAAAAACTAACTTACCCTATGGAAAAGTACCTTGACCCAAACAGACCGTTCAAATGTGACGTATGCAAAGAATCTTTTACGCAAAAGAACATTTTGTTAGTACACTACAATAGCGTGAGCCATTTACATAAATTGAAGCGAGCTATGCAAGAACAacagaataataataaccctCCCGTGTCGCCTGGGGCAGGCTCTGCGCCCTCTAATTTGACACTCACTCCCAAGAGTACATCGAGTGAGGAGGATGATCGCAAACGGTACAAATGTAACATTTGTAAAGTTGCGTACACCCAAGGAAGCACGCTTGACATTCACATGAGGTCAGTTCTACATCAAACACGCGCGGGCAAGTTGCAAGAGCTCGCCGCGGCCGGCCACGTGGACTTGTCAAGGCCCTTGGTAGAACAGCCGGATCGGACCGACCCCGCCAAAATCTTACAAGACGTGTTGTCGCCGAAAAATACATCCCCTTCATCTACAAGCAGTGGGGGCCCGCGTTCATCGCCCCCTGCGCGCCCAGGTAGTCCGCGATCCCCGCGCACAGGTAATACTGCGTGCGAGCGCTGTCACGGGTCATTTTCAACTGGGGAGCTACTCGAAGCACATCGAGCGACATCATGCCCGTTTGGCGATGCGCGCGCGCACTCGCCGCTAGGTGAGGCTGAAACAGCTGCTCTTGACGAGATGGTGGCCAAGGGCCACACGCCCAAACGCAATTCACAAATGTATAAGCAACTGTTAGAAACTTTCGGTTTCGATCTTGTCATGCAATACAATGAAAATCAGCGCAGAAAAATGCAAGAAGAACGGGAGATGGCGCGCGTACCTAGTCCGCCGCCACCGCCTCCTGAAGAGAAGCCCCCGGATGGTGAAAGTAAATCAACGTGTCAACATTGCAATAAAGAGTTTTCTAGTGTGTTCGTTCTTAAAACTCATTGTGAGGAAGTGCATAAAGACAAAGTACCGCTGGAATTTCTGGAGCAGTTCGCTGAACAGTTCAAATCGGAGTATGAGAGGAAGTCTGGTGCGCCGAACTCACCTCGCGCGGCTTCTCCTGCGCCGCAGGGTGAAAGGTCACCGTCTCCACGTATTGATAACAATGGAAACTTCAGTGAAAATGGGAACGCACAGGGAGATGCGCAAAATGGTGCGTTACTAGCGCAAATGCAAGACATGCAGGCAGCTTTGAACATGATCCAACTGCAGCAGCAGCTGGGGCAACTGCACCCGATGGTAGCTCAAATGCTTACGTTAGGTCTTCCTCTCGGTCTAAACGTAGGCGCACTGGCAGCGATGAACCTCCAACCGCCTCTGGTTCCGCTGATGCTGCCGCCTCCTCCATTCGACACTATGCCCTTCGCTCACGATGCTCAAATGAAACAACAGCAATTATTACAGCAGCAACAGCAGGCTAACGCTGCAGCTGGTCAAAAGAGAGCTCGTACTCGCATCACTGACGAGCAATTGAAGATTTTGCGAGCGCACTTTGACATTAACAACTCGCCCAGCGACGAGGCTATCGCGAAAATGGCCCAACAGTCTGGACTTGCTACAAAGGTAATAAAACATTGGTTCAGGAACACTCTTTTCAAGGAGCGTCAGCGGAATAAGGATTCACCGTACAACTTCAATAATCCACCTTCCACGACACTGAACCTCGAAGAGTATGAAAAGACCGGTGAAGCTAAAGTGACTACTTTGGATTCATCAGCAAGTTCAGATGAAGGCAAGCCACCGCCTGAAAAAAAGGCAAAAATCGAGGACGCCATGATAATACCACAGGAAGTAAAGTCAGAGCCTAATGATGAGCCATCCATGGAAGAGAAATACAACTCGTACGATGATCGCCACCAGGAAGATAAAAGCTTTATCTTTCCTCAAGCGCCGTCACAAAGTCCAGCACCTATAATACATACAAATGACCACCATCACCAAAACAAATCGCGACCGCAAACTCCAACGCATATGTCGCTGAACTCATTGATCCAGTCTCAGTTAGATTCAATTCCGGCTACGAGTATACCACAGCCGCCACATCCGTCGATGCTACCACCAAAAATCAATCCTAACTTCACGTCCCCAAACTCCGCGCCCCCGAACGTCCTACCTTTGACCCCGAATCGCAGCCTCAGTCCTGGCAGGGGACCGGCCGATTTCGGACTTTCCGGGGGCAATTCGAACGGATCCAACAGCTCAACGGGGTCTTCTGGCAAACGCGCCAACAGAACTAGGTTCACCGACTATCAAATAAAAGTATTACaagagttttttgaaaacaatGCCTATCCCAAAGATGATGATCTCGAATATTTATCGAAGTTACTGGGATTGAGTCCGAGAGTAATAGTGGTGTGGTTTCAAAATGCGCGCCAGAAAGCTAGAAAAGTCTATGAAAACCAGCCAGCAGCAGATCCACCTGCAAGCGCCACTGACGAAGCTAATAGATTTCAACGCACTCCAGGTCTTAATTATCAGTGCAAAAAGTGCCAATTAGTATTCCAAAGGTACTATGAACTTATAAGACATCAGAAGACTCATTGTTTTAAAGAAGAAGATGCTAAAAGATCAGCACAAGCACAGGCGGCAGCTGCTCAGGTAGCTGCCACATTGAGTAGTGAGGACTCCAACTCGAGCAATGTTGAGCACCACCCTCCACACGTACCGGTCTCGCCCGCCCCACCCCGCACACCCACTCCTGCGGCGCCCAGCTACCCAGTGTCTCCGGCACCACCAACGCCTTTAACACCCGTCACTCCACTATCACACGCACGTGAAGAAAAAGATGGAAATTTTCAATGTGATAAATGCAACCTAGTCTTCCCTCGGTTTGACTTATGGCGGGAACATCAACTTGTTCACATAATGAATCCAAATTTATTCCCCACATACCCGCCGGATTCCCCTTTTGGGATCCTTCAGCAGCACGCGCAGCTGCAACAGCTAAATGCGTCCCTTGGGAGTGATGAGGCTCGCCATCCTTTAGTGGCGGCCCTTAATCAACAAGTAGCTAAGAGGAAATTCGATGAATATGAAGAAGTGGAAACTGGTGAGCAGCCAAAAGACAAACGCTTACGAACTACTATTCTACCGGAACAACTGGATTACCTCTACCAAAAATACCAAATCGAATCTAACCCGTCACGGAAGATGCTTGAAAACATAGCACGTGAAGTTGgactaaaaaaaagagtggtacAAGTTTGGTTTCAAAATACACGAGCACGTGAGAGGAAAGGACAGTTTCGTGCGCATGCACAAGTGATAAATAAACGATGTCCGTTTTGTCCAGCTTTGTTCAAGGTGAAGAGCGCATTAGAAAGTCATTTGAGCACTAAACACGCAGATCAGTGTGCAAGAGGAGAAATCAACGTAGACGCGCTGCCCGACGAAGAATTAAGTACAGAATCAACACCGAGTTTTGGCTCCCAACAAAGTGACCGGCAGCAAAATTTTTCGCAAGCGGGGGCTCCCATGTTGCCCCCTATTTTTCCACCTTTTCACTCAGACATGGAGAAGTTTATCAAGCAGTACAGTGAGGAGTCAATGAAACGATATGTAAGTGAATTACAAGCGCATGCCGCAGCCCAACAGAACGGTGGCGGAAACAATGAAGGATCTGAGCGACGCCCAGAACATGGAAAATCGGAGATACCTTTAGATCTCAGCAAACCAGTTGATCTGTCACGACCCGGGTCGGACGCCGACGAGCGTTCTGACACAGCTTCTGAGACTATGGAGTTCTACGAGGAAGATGAGCCCACCTCGCCACTACCGGGCCAACAGCAGTCGGCGCGACCTCCTGGCAAACGATACCGAACGCAAATGTCATCCTTGCAAGTGAAGATAATGAAATCGTTATTCGGCGACTATAAAACTCCTACTATGGCCGAGTGCGAGGCGCTCGGGCGGGAAATCGGGCTGCCCAAACGCGTGGTGCAAGTTTGGTTCCAAAACGCACGTGCCAAAGAGAAGAAGGCGCGCCTGGCCGCCGGACTCATGGAGGTGTCCGACGCGCCGCCGCCGGAGGAGTGTCGAGTTTGTGACTTCAAGTACAGTCATAAGTATTCGGTGCAGGACCACGTGTTCACGCGCGGCCACATCGCGGCCGTGCGTGCGCGCCTCGAAagcggcgcgggcggcggcgAGGACAGCACGCTCGCCCTCATGCAGATGGCGGCGCGCCTCGAGAGCGGCATGGGCGGCGACCTGCACAGCGCCTTCCTGCGACCGCAGCTCGCCGGAAACGGTGAGTGCACGACTTGA
Protein Sequence: MWCFLRKDPLSIDKKRQRSRLCRQDTKEPIDQKPELTQEQKMMRFLEQHQQQQQQQQQQQQHVQQQSQQGPSEREEERETPGPHTCPYCNFSCSNESRLHAHVSSVHGDPSRHFICPLCQDGFKERPALERHVMQIHSVNSEGLQRLLLLVDQSHWLNGGAQSQRDESRQGDDEREISSPRSEGSADGETERCSTCNRTFRNVDELCQHQNESGHLELKQTPQGPGYVCWKKGCNRYFDAAHALQNHFREAHARNSIANMSVSEKHVYKYRCNQCSLAFKTIEKLQLHSQYHVIRDATKCVLCGRSFRSVLALQKHVESSHPELSEEELSAFKRSLASNPLLQAAQGTALDAATAELLRKEALRTPDDDLADMEDRDSSATVADESGHNDAENSDDSIIYKDQQFLEDYLNSQTMAEDSYNDPNRKYKCHRCKVAFTRQSYLTSHNKTLLHRKGEKLTYPMEKYLDPNRPFKCDVCKESFTQKNILLVHYNSVSHLHKLKRAMQEQQNNNNPPVSPGAGSAPSNLTLTPKSTSSEEDDRKRYKCNICKVAYTQGSTLDIHMRSVLHQTRAGKLQELAAAGHVDLSRPLVEQPDRTDPAKILQDVLSPKNTSPSSTSSGGPRSSPPARPGSPRSPRTGNTACERCHGSFSTGELLEAHRATSCPFGDARAHSPLGEAETAALDEMVAKGHTPKRNSQMYKQLLETFGFDLVMQYNENQRRKMQEEREMARVPSPPPPPPEEKPPDGESKSTCQHCNKEFSSVFVLKTHCEEVHKDKVPLEFLEQFAEQFKSEYERKSGAPNSPRAASPAPQGERSPSPRIDNNGNFSENGNAQGDAQNGALLAQMQDMQAALNMIQLQQQLGQLHPMVAQMLTLGLPLGLNVGALAAMNLQPPLVPLMLPPPPFDTMPFAHDAQMKQQQLLQQQQQANAAAGQKRARTRITDEQLKILRAHFDINNSPSDEAIAKMAQQSGLATKVIKHWFRNTLFKERQRNKDSPYNFNNPPSTTLNLEEYEKTGEAKVTTLDSSASSDEGKPPPEKKAKIEDAMIIPQEVKSEPNDEPSMEEKYNSYDDRHQEDKSFIFPQAPSQSPAPIIHTNDHHHQNKSRPQTPTHMSLNSLIQSQLDSIPATSIPQPPHPSMLPPKINPNFTSPNSAPPNVLPLTPNRSLSPGRGPADFGLSGGNSNGSNSSTGSSGKRANRTRFTDYQIKVLQEFFENNAYPKDDDLEYLSKLLGLSPRVIVVWFQNARQKARKVYENQPAADPPASATDEANRFQRTPGLNYQCKKCQLVFQRYYELIRHQKTHCFKEEDAKRSAQAQAAAAQVAATLSSEDSNSSNVEHHPPHVPVSPAPPRTPTPAAPSYPVSPAPPTPLTPVTPLSHAREEKDGNFQCDKCNLVFPRFDLWREHQLVHIMNPNLFPTYPPDSPFGILQQHAQLQQLNASLGSDEARHPLVAALNQQVAKRKFDEYEEVETGEQPKDKRLRTTILPEQLDYLYQKYQIESNPSRKMLENIAREVGLKKRVVQVWFQNTRARERKGQFRAHAQVINKRCPFCPALFKVKSALESHLSTKHADQCARGEINVDALPDEELSTESTPSFGSQQSDRQQNFSQAGAPMLPPIFPPFHSDMEKFIKQYSEESMKRYVSELQAHAAAQQNGGGNNEGSERRPEHGKSEIPLDLSKPVDLSRPGSDADERSDTASETMEFYEEDEPTSPLPGQQQSARPPGKRYRTQMSSLQVKIMKSLFGDYKTPTMAECEALGREIGLPKRVVQVWFQNARAKEKKARLAAGLMEVSDAPPPEECRVCDFKYSHKYSVQDHVFTRGHIAAVRARLESGAGGGEDSTLALMQMAARLESGMGGDLHSAFLRPQLAGNGECTT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01230332;
90% Identity: iTF_01230332; iTF_00236930; iTF_00236472; iTF_00710855; iTF_00711231; iTF_00786253; iTF_00785838;
80% Identity: iTF_01230332;