Basic Information

Insect: Eurema mandarina
Gene Symbol: ZFHX3
Assembly: GCA_018238005.1
Location: DWAJ01001854.1:12755-19832[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.042 3.7 8.8 5.2 1 23 82 105 82 105 0.95

2 15 0.01 0.9 10.7 0.0 1 23 112 135 112 135 0.95

3 15 0.0058 0.51 11.5 4.1 2 22 190 210 190 213 0.91

4 15 0.47 41 5.5 0.7 1 23 225 250 225 250 0.92

5 15 0.0095 0.83 10.8 1.3 1 23 268 290 268 290 0.97

6 15 0.0014 0.12 13.5 0.3 2 23 297 319 296 319 0.96

7 15 0.00022 0.02 16.0 3.1 1 23 425 449 425 449 0.92

8 15 0.0092 0.8 10.9 0.7 1 22 469 490 469 493 0.89

9 15 0.00092 0.08 14.0 0.2 1 23 540 564 540 564 0.93

10 15 1.4 1.2e+02 4.0 0.1 3 21 639 657 638 658 0.90

11 15 0.67 59 5.0 3.5 2 19 748 765 747 770 0.91

12 15 2.4e-05 0.0021 19.0 2.9 1 23 1275 1297 1275 1297 0.99

13 15 0.00062 0.054 14.6 0.3 1 23 1383 1405 1383 1405 0.98

14 15 0.0058 0.51 11.5 0.4 2 23 1543 1565 1542 1565 0.97

15 15 0.19 16 6.8 1.4 2 22 1793 1813 1792 1816 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.042	3.7	8.8	5.2	1	23	82	105	82	105	0.95
2	15	0.01	0.9	10.7	0.0	1	23	112	135	112	135	0.95
3	15	0.0058	0.51	11.5	4.1	2	22	190	210	190	213	0.91
4	15	0.47	41	5.5	0.7	1	23	225	250	225	250	0.92
5	15	0.0095	0.83	10.8	1.3	1	23	268	290	268	290	0.97
6	15	0.0014	0.12	13.5	0.3	2	23	297	319	296	319	0.96
7	15	0.00022	0.02	16.0	3.1	1	23	425	449	425	449	0.92
8	15	0.0092	0.8	10.9	0.7	1	22	469	490	469	493	0.89
9	15	0.00092	0.08	14.0	0.2	1	23	540	564	540	564	0.93
10	15	1.4	1.2e+02	4.0	0.1	3	21	639	657	638	658	0.90
11	15	0.67	59	5.0	3.5	2	19	748	765	747	770	0.91
12	15	2.4e-05	0.0021	19.0	2.9	1	23	1275	1297	1275	1297	0.99
13	15	0.00062	0.054	14.6	0.3	1	23	1383	1405	1383	1405	0.98
14	15	0.0058	0.51	11.5	0.4	2	23	1543	1565	1542	1565	0.97
15	15	0.19	16	6.8	1.4	2	22	1793	1813	1792	1816	0.88

Sequence Information

Coding Sequence: ATGATTGTTTGCCCGTCCTGTATCTCCTTTGTGTGCGAAATTACAATATACTTGTTACATACTAAGGAGCCTATTGATCAGAAACCGGAATTGACTCAAGAACAAAAGATGTTGCGATTTTTGGAACAACACCAACAACAGCAGCAACAACAGCATCAACAGCAACAGCAACAACAGCATCAACAACTTACACAACCGATACAACAAAGCGAAGAGAAAGATGAAGAAGAAGTTTCTGGATCGCATACGTGTCCgtattgcaattttacttgTGATAATGAAAGTAAACTTCACGCTCATGTCAGTTCAATGCACGCTGACACCGCGCGTCACTTTATTTGTCCTTTATGCCAGGATGCGTTCAAGGATAGACCTGCTCTCGAACGCCACGTGATGCAAATTCATTCTGTGAACTCCGAAGGTTTGCAGCGCCTGCTATTGTTAGTTGACCAGAGCCATTGGTTGAACGGTGGTGCGCAGGCGCAACGTGAGGAATCGAGACAAGGTGATGAAGACCGCGAGATATCTTCGCCGCGCTCGGAAGGCAGCGCTGATGGAGAGACAGAGAGGTGCTCGACCTGCAACAGAACCTTCCGCAATGTCGATGAACTGTGTCATCATCAAAATGAATCAGGACATTTAGAACTGAAACAAACACCTCAAGGTCCTGGTTACGTGTGCTGGAAGAAGGGATGCAACCGTTATTTTGAAGCAGCCCATGCTCTTCAAAATCATTTCAAAGAAGCCCACGCCCGCAACTCGATCGCCAACATGTCGGTATCTGAGAAgcatgtttataaatatcgcTGTAATCAATGCAGTCTCGCTTTCAAAACTGTTGAGAAGTTACAGTTACATTCACAATATCATGTTATTCGCGATGCAACAAAATGTGTCCTGTGTGGACGCAGCTTTAGATCGATACTGGCTTTACAGAAACATGTTGAAACTTCACATCCTGAATTGTCTGAAGATGAACTATCTGCTTTTAAGCGAAGTTTAGCTTCTAaccctttattacaatcggGCCAAGGAACCGCTCTCGATCCGGCCGCGGCTGATTTATTGCGAAAAGAGGCATTGAGAACGCCTGATGATGATTTAGGTGAAATGGAAGACAGAGATTCCAGCGCCACCGCTGCTGACGAGTCCGGTCACAACGACGCTGAAAATTCAGACGACTCAATAATATACAAAGACCAACAATTCCTAGAAGATTATTTGAATTCACAAGCTATGGCTGAAGATTCTTATAATGATCCTaacagaaaatacaaatgtcatCGCTGCAAAGTTGCATTTACAAGACAGTCTTATCTAACAGCTCATAACAAGACGCTTTTACATAGAAAAGGCGAAAAACTAACTTATCCTATGGAAAAATATCTAGATCCGAACAGACCGTTTAAATGTGACGTATGCAAAgaatctttcacgcaaaagaATATCTTATTGGTACATTACAATAGTGTAAGTCATTTACACAAATTGAAGCGCGCTATGCAAgaacaacaaaacaataacaatccTCCCGTGTCGCCGGGAGCAggtacagcgccatctaattTGACTCTAACACCTAAAAGTACATCGAGTGAAGAGGACGACCGCAAACGATATAAATGCAACATATGTAAAGTAGCCTATACGCAAGGCAGCACGTTAGATATTCATATGCGATCAGTTTTGCATCAAACACGTGCCGGCAAGTTGCAAGAGCTAGCTGCGGCGGGCCACGTTGACTTGACGCGGCCTTTAGTAGAGCAGCCAGATAGAAACGACCCCGCTAAAATTTTACAAGACGTATTGTCGCCAAAAAATACATCCCCTTCGTCTACGAGTAGCGGGGGGCCGCGATCTTCGCCCCCCGCTCGCCCAGGTAGCCCCCGGTCCCCACGGACAGGTAGTGCCTCGTGCGAACGATGCCACGCGTCATTCCCGACTGGGGAGCTACTCGACGCACATCGCGCTACTCTATGTCCGTTTGGCGATGCGCGGGCGCACTCGCCGCTTGGTGACGCAGAAGCAGCCGCTCTCGACGAGATGGTAGCGAAGGGCAACCCGCCCAAACGGAACTCACAAATGTATAAGCAACTATTAGAGACGTTCGGTTTCGATCTCGTGATGCAGTACAACGAGAATCAGCGCCGCAAGCTGCAGGAAGAACGTGAGATGGCGCGCGCCCCGAGCCCGCCGCCTCCGCCACCGGAGGAAAAGCCTCCGGATAGTGAAACGAAGAGCACGTGCCAGCATTGTAATAAAGAGTTTTCTAGTGTGTTCGTTCTTAAGACTCATTGTGAAGAAGTGCATAAAGACAAAGTTCCGCTCGAATTTTTGGAACAGTTCGCGGAGCAATTCAAATCTGAATATGAGAGGAAGTCTGGTGCGCCGAACTCGCCGCGTGCCGCGTCGCCCGCTCCTCAGGGTGACCGCTCGCCATCGCCCCGCGGTGACAGTAACAGCAACTTCAATGAGAATGCCAATGGATCTGGTGAGGCGCAAGCCGGAGCGTTGCTCGCTGCACAAGTGCAAGAAATGCAAGCGGCGCTTAATATGTTGCAATTACAGCAACAGCTGGGTCAACTGCATCCTATGGTTGCTCAAATGCTATCCCTTGGACTGCCTCTTGGATTGAATGTGGGAGCGCTGGCCGCTATGAACCTGCAACCTCCACTGGTACCGCTCATGCTGCCGCCGCCACCGTTCGATGCGATGCCTTTCGCTCATGACGCACAATTAAAGCAACAACAACTCATCCAGCAACAACAACAGGCGAACGCCGCAGCTGGACAGAAAAGAGCTCGTACGCGTATTACTGACGagcaattgaaaattttacgaTCTCATTTTGACATTAATAACTCGCCGAGTGATGAAGCAATTGCGAAAATGGCTAAACAATCTGGCCTAGCTACAAAGGTCATCAAACATTGGTTCCGAAATACACTGTTTAAGGAACGCCAACGAAACAAAGATTCACCTTACAACTTTAATAACCCACCATCGACGACACTCAACCTTGAGGAGTATGAAAAGACCGGGGAAGCTAAAGTGACACCTTTAGATTCATCAGCGAGCTCCGATGAGGGCAAACCACCGCCtgaaaaaaaagcaaaaactgAAGAAATGTCAATGACCCCACAACAAGAGGTCAAATCTGAACCCAATGAAGAACCTACAATGGAGGAAAAATACAATTCTTACGACGACCGACATCAAGAGgacaaaagttttatttttcctcaAGTTCCATCCCAGAGTCCTGCATTGAGCAGCTCAGATCTGCACCAGAGCATATCTCGTCCTCAAACACCAACGCATCTGTCATTGAATTCCTTAATACAATCTCAATTGGATTCAATACCAGCTACTAGCATACCTCAACCACCACATCCATCTATGCTACCACCGAAATTAAATCCTAATTTCACGTCCCCAAACTCCGCGCCCCCGAACGTCCTACCTTTGACCCCAAATCGCAGCCTCAGTCCTGGCAGGGGACCGGCCGATTTCGGACTTTCCGGGGGCAACTCGAATGGATCCAACAGCTCGGGGTCTTCTGGCAAACGCGCCAACAGAACTAGATTTACTGATTACCAGATCAAAGTATTGCAAGAGTTTTTTGAAAACAATGCCTACCCAAAGGATGACGATCTAGAATATCTTTCTAAATTATTGGGACTTAGCCCAAGAGTCATTGTAGTTTGGTTTCAAAACGCTAGACAGAAAGCAAGAAAAGTATACGAGAATCAACCAGCAGCAGATCCACCAGCAGGATCAATGGATGACGCGAATAGATTTCAACGAACACCAGGTTTAAACTACCAATGTAAAAAATGCCAATTAGTATTTCAACGGTATTACGAGTTGATAAGACATCAGAAGACTCATTGTTTTAAGGAGGAGGATGCGAAACGATCAGCGCAGGCACAAGCGGCAGCTGCGCAAGTTGCTGCTACATTGAGCAGCGAAGACTCAAACTCCAGCACCGTAGAACACCACGTTCCGCATGTGCCAGTGTCACCGGCACCACCTCGTACTCCCACACCTGCCGCCCAGAACTATCCCGTCTCTCCGGCTCCTCCTACTCCACATACACCAATCACACCTCTTTCCCATACACCTAGAGAGGAGAAGGATGGAAATTTTCAATGTGATAAATGCAATCTAGTTTTTCCCCGATTCGACTTATGGCGAGAACATCAACTTGTTCATATAATGAACCCAAATTTATTTCCCACCTACCCCCCAGATTCCCCTTTTGGGATCTTACAACAACATGCTCAATTACAACAACTAAACGCTTCTCTGTCGAATGAAGAAGCTCGGCATCCATTAGTGGCAGCCTTGAACCAGCAAGTCGCCAAAAGGAAATTTGATGAATTTGAAGAAGCAGATACGGGTGAACAGCCAAAAGACAAAAGATTAAGAACTACAATTTTACCCGAACAATTGGACTACTTATATCAAAAGTACCAAATTGAATCTAATCCATCAAGAAAAATGCTTGAGAATATTGCTCGGGAggttggattaaaaaaaagagttgTTCAAGTTTGGTTTCAAAACACGAGAGCTCGTGAAAGAAAGGGTCAATTTCGTGCACACGCACAAGTCATAAACAAACGTTGCCCCTTTTGCCCAGCTTTATTCAAAGTTAAAAGCGCACTAGAAAGCCACTTGAGTACAAAACATGCCGATCAGTGTGCTAGAGGAGAGATCAATGTGGATGCTCTACCCGATGAAGAGTTAAGTACAGAATCAACACCTAGCTTTGGATCCCAACAAAGTGACAGACAGCAAAATTTTTCCCAGGCGGGGGCTCCCATGTTGCCCCCTATTTTTCCGCCGTTTCACTCAGACATGGAGAAATTTATCAAACAGTATAGTGAAGAGTCAATGAAGCGCTACGTTACCGAGCTTCAGGCTCACGCTGCTGCACAACAAAATGGCAGTGGCAATGAATCATCTGAGAGACGACCTGAACATGGAAAATCTGAAATACCCTTAGATCTCAGCAAACCTGTAGACTTATCGCGACCGGGATCTGATGCCGACGAAAGATCAGATACAGCATCTGAAACCATGGAGTTTTACGAGGACGACGATCCAACATCCCCATTAACGGGTCACCCTAATCAAAGGCAACCTGGCAAACGTTTCCGCACTCAGATGTCTTCGATACAAGTGAAGATAATGAAAGCTTTGTTTAGCGACTACAAAACGCCAACTATGGCGGAATGCGAAGCGCTCGGGCGAGAAATTGGACTACCGAAGCGAGTGGTACAAGTGTGGTTCCAAAACGCTCGTGCCAAAGAGAAGAAGGCGAGACTGGCGGCTGGTCTACCGGAGGTGTCAGACGCGCAACCTCCGGACGAGTGTCGTGTCTGTGACTTCAAGTACAGTCACAAATATTCAGTGCAAGATCACGTCTTCACGCGGGGTCATATAGGTGCGGTGCGTGCCCGTCTCGAGAACAGCGCGGGCGCCGGCGACGACGGCACGCTAGCGCTAATGCAGATGGCAGCACGTCTGGAGAGCGGGCTTGGCACTGAGCTGCACAACGCCTTCCTCAGACCTCAGCTCGCGGGCAACGGTGAGTGTACTTGA
Protein Sequence: MIVCPSCISFVCEITIYLLHTKEPIDQKPELTQEQKMLRFLEQHQQQQQQQHQQQQQQQHQQLTQPIQQSEEKDEEEVSGSHTCPYCNFTCDNESKLHAHVSSMHADTARHFICPLCQDAFKDRPALERHVMQIHSVNSEGLQRLLLLVDQSHWLNGGAQAQREESRQGDEDREISSPRSEGSADGETERCSTCNRTFRNVDELCHHQNESGHLELKQTPQGPGYVCWKKGCNRYFEAAHALQNHFKEAHARNSIANMSVSEKHVYKYRCNQCSLAFKTVEKLQLHSQYHVIRDATKCVLCGRSFRSILALQKHVETSHPELSEDELSAFKRSLASNPLLQSGQGTALDPAAADLLRKEALRTPDDDLGEMEDRDSSATAADESGHNDAENSDDSIIYKDQQFLEDYLNSQAMAEDSYNDPNRKYKCHRCKVAFTRQSYLTAHNKTLLHRKGEKLTYPMEKYLDPNRPFKCDVCKESFTQKNILLVHYNSVSHLHKLKRAMQEQQNNNNPPVSPGAGTAPSNLTLTPKSTSSEEDDRKRYKCNICKVAYTQGSTLDIHMRSVLHQTRAGKLQELAAAGHVDLTRPLVEQPDRNDPAKILQDVLSPKNTSPSSTSSGGPRSSPPARPGSPRSPRTGSASCERCHASFPTGELLDAHRATLCPFGDARAHSPLGDAEAAALDEMVAKGNPPKRNSQMYKQLLETFGFDLVMQYNENQRRKLQEEREMARAPSPPPPPPEEKPPDSETKSTCQHCNKEFSSVFVLKTHCEEVHKDKVPLEFLEQFAEQFKSEYERKSGAPNSPRAASPAPQGDRSPSPRGDSNSNFNENANGSGEAQAGALLAAQVQEMQAALNMLQLQQQLGQLHPMVAQMLSLGLPLGLNVGALAAMNLQPPLVPLMLPPPPFDAMPFAHDAQLKQQQLIQQQQQANAAAGQKRARTRITDEQLKILRSHFDINNSPSDEAIAKMAKQSGLATKVIKHWFRNTLFKERQRNKDSPYNFNNPPSTTLNLEEYEKTGEAKVTPLDSSASSDEGKPPPEKKAKTEEMSMTPQQEVKSEPNEEPTMEEKYNSYDDRHQEDKSFIFPQVPSQSPALSSSDLHQSISRPQTPTHLSLNSLIQSQLDSIPATSIPQPPHPSMLPPKLNPNFTSPNSAPPNVLPLTPNRSLSPGRGPADFGLSGGNSNGSNSSGSSGKRANRTRFTDYQIKVLQEFFENNAYPKDDDLEYLSKLLGLSPRVIVVWFQNARQKARKVYENQPAADPPAGSMDDANRFQRTPGLNYQCKKCQLVFQRYYELIRHQKTHCFKEEDAKRSAQAQAAAAQVAATLSSEDSNSSTVEHHVPHVPVSPAPPRTPTPAAQNYPVSPAPPTPHTPITPLSHTPREEKDGNFQCDKCNLVFPRFDLWREHQLVHIMNPNLFPTYPPDSPFGILQQHAQLQQLNASLSNEEARHPLVAALNQQVAKRKFDEFEEADTGEQPKDKRLRTTILPEQLDYLYQKYQIESNPSRKMLENIAREVGLKKRVVQVWFQNTRARERKGQFRAHAQVINKRCPFCPALFKVKSALESHLSTKHADQCARGEINVDALPDEELSTESTPSFGSQQSDRQQNFSQAGAPMLPPIFPPFHSDMEKFIKQYSEESMKRYVTELQAHAAAQQNGSGNESSERRPEHGKSEIPLDLSKPVDLSRPGSDADERSDTASETMEFYEDDDPTSPLTGHPNQRQPGKRFRTQMSSIQVKIMKALFSDYKTPTMAECEALGREIGLPKRVVQVWFQNARAKEKKARLAAGLPEVSDAQPPDECRVCDFKYSHKYSVQDHVFTRGHIGAVRARLENSAGAGDDGTLALMQMAARLESGLGTELHNAFLRPQLAGNGECT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01230332;
90% Identity: iTF_01230946;
80% Identity: iTF_00710855;