Basic Information

Insect: Polia nebulosa
Gene Symbol: Ctcfl
Assembly: GCA_951329385.1
Location: OX589587.1:4299626-4317510[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.012 2.1 10.8 5.7 1 23 180 202 180 202 0.98

2 11 7.3e-05 0.012 17.8 1.5 1 23 208 230 208 230 0.98

3 11 8.4e-05 0.014 17.6 1.7 1 23 236 259 236 259 0.96

4 11 0.035 6.1 9.3 3.3 1 21 265 285 265 287 0.95

5 11 0.00013 0.021 17.1 2.7 1 23 293 315 293 315 0.99

6 11 4.2e-05 0.0072 18.5 3.1 1 23 321 343 321 343 0.98

7 11 0.0062 1.1 11.7 0.5 1 23 351 374 351 374 0.96

8 11 0.026 4.4 9.8 4.5 2 23 381 402 380 402 0.96

9 11 2.7e-05 0.0046 19.2 2.6 1 23 408 430 408 430 0.98

10 11 1.6e-05 0.0027 19.9 1.8 1 23 436 459 436 459 0.93

11 11 0.00017 0.029 16.7 6.5 1 23 473 495 473 495 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.012	2.1	10.8	5.7	1	23	180	202	180	202	0.98
2	11	7.3e-05	0.012	17.8	1.5	1	23	208	230	208	230	0.98
3	11	8.4e-05	0.014	17.6	1.7	1	23	236	259	236	259	0.96
4	11	0.035	6.1	9.3	3.3	1	21	265	285	265	287	0.95
5	11	0.00013	0.021	17.1	2.7	1	23	293	315	293	315	0.99
6	11	4.2e-05	0.0072	18.5	3.1	1	23	321	343	321	343	0.98
7	11	0.0062	1.1	11.7	0.5	1	23	351	374	351	374	0.96
8	11	0.026	4.4	9.8	4.5	2	23	381	402	380	402	0.96
9	11	2.7e-05	0.0046	19.2	2.6	1	23	408	430	408	430	0.98
10	11	1.6e-05	0.0027	19.9	1.8	1	23	436	459	436	459	0.93
11	11	0.00017	0.029	16.7	6.5	1	23	473	495	473	495	0.96

Sequence Information

Coding Sequence: ATGCCACCACCAGATAAAAAGGAGAAGAGCAAGCAAGCGCTCATCCAAACTTATTTGAACCAAGGTGCTGTCATTGCAGtTAACACCGCAACAGACGAGAAATGTTTGCCAACCGGATTGGTTGAATATTTCGTTGACGAAGATGGAAAGTACTACTACCAGTCAGCGGTTGAAGGACAGACCTTGGTCATGGAAAACTCTGAAGACAATGAGCAAACTGAGGAGGCTGCTGAATCCTCGGATGTAATAATGAATGATCAAGAAGAAACGTACCAGACGGTCACCTTTCTCCCTAATACTGAGTCCAATGGGGAAGTGAGCTACGTACTAGTGGTTCAGGACGAGTCCAAGGGGGTGGTCAATATTGATCTCAAGGTGGACCAGTCCGAGGCAGAGGACAAAGGCAACGATGACGTGTATAACTTTGACGACGAGGAAGGCGGCGAGGAGGAggaggaagaagaagaggagCCGGCCGCCGACGGCACCAAGGCCAAGGGCGCGCTGAAGCCGCGCACCAAGCACACGCGCACGCACTTCAACTGCAACTTCTGCAGCTACACTAGTCACCGCCGATACCTTCTTCTGCGCCACATGAAGTCTCACTCGGAGGACCGGCCGCACAAGTGCACTGTGTGCGAACGCGGCTTCAAGACCATGGCTTCCCTGCAGAACCACGTCAACATGCACAACGGTGTCAAGCCACACGTCTGCAAGTACTGCAACAGCCCCTTCACTACTTCGGGCGAGTTGGTACGCCACGTGCGCTACAAGCATACGCACGAGAAGCCGCACAAATGCACGGAGTGTGACTACGCTTCCGTCGAGCTGTCGAAACTTCGGCGCCACGTTCGCTGTCACACCGGCGAGAGACCCTACCAGTGCCCGCACTGCACGTACGCGTCACCAGACACTTTCAAGCTGAAGCGCCACTTGCGGACGCACACCGGCGAGAAGCCGTACAAGTGCGAGAGCTGCAACATGTGCTTCACGCAGTCCAATTCGCTGAAGGCGCATCGACTGATCCACAACGTATCGGAGAAGCCGGTATACGCTTGTGAGCTGTGCCCGGCCAAGTGCGGCCGCAAGACGGACCTGCGCATCCATGTACAGAAGTTGCACACTTCTGACAAGCCGCTCAAGTGTCGCCGCTGTGGAAAGACTTTCCCGGACCGCTACTCCTGCAAGGTCCACAATAAGACGCACGAGGGCGAGAAGTGCTTCAAGTGCGACGTGTGCCCCTATGCGTCCACCACACAGCGTCACCTCAAGACGCACATGCTCAAACATACCGACGAGAAGCCTTTCCTCTGCGACATGTGTGATCAGTCATTCAGGCAAAAGCAATTGCTGCGTCGTCACCAAAACTTATATCACAACCCGAACTACGTTCCAAAGCCGCCAAAGGAGAAGACCCACTGCTGCCACGAATGCCAACGCATGTTCGCGCACAAGGGCAATCTGATCCGCCACCTGGCCGTGCACGACCCGGAATCTGGCCACCACGAGCGCGCGCTGGCGCTCAAGATCGGACGCCAGAGGAAGGTGCAGTTCATCGATGGAAAGCCAACTAGGGATCTTCGCGTGGTGGATTCCGCCGACCCCGAGCACTTGATGAAGCTGGGTCTCACCAACAAAGAGTTGAAGCGGGGCGAGCTCGTCACCGTAGCCGACGGGAACGGCCAGCAGTACGTGGTGCTCGAGGTTATTCAGCTCGAGGACGGCACCGAGCAGCAGGTGGCCGTCGTGGCACCCGGAGAATTCATGGACGTAGATGAGCCTGCTTATTCAACAGAAGAAGATGAAgaggaggaagaagaagaagaggagGACGAAGAAGAAGAGGGTGAGGACAGGAGTTTCGTAGTCAAGGCGCCCATGGTCTCTCAGAGCATCAAACTCGAGAAGGAGGTCGACACATGCTTCGGATTCGATGAGGAGGACGAGGATCCCGACGATGTTAATTATACTGATAAAGTAGTGTTGCGCTTAGTTTAG
Protein Sequence: MPPPDKKEKSKQALIQTYLNQGAVIAVNTATDEKCLPTGLVEYFVDEDGKYYYQSAVEGQTLVMENSEDNEQTEEAAESSDVIMNDQEETYQTVTFLPNTESNGEVSYVLVVQDESKGVVNIDLKVDQSEAEDKGNDDVYNFDDEEGGEEEEEEEEEPAADGTKAKGALKPRTKHTRTHFNCNFCSYTSHRRYLLLRHMKSHSEDRPHKCTVCERGFKTMASLQNHVNMHNGVKPHVCKYCNSPFTTSGELVRHVRYKHTHEKPHKCTECDYASVELSKLRRHVRCHTGERPYQCPHCTYASPDTFKLKRHLRTHTGEKPYKCESCNMCFTQSNSLKAHRLIHNVSEKPVYACELCPAKCGRKTDLRIHVQKLHTSDKPLKCRRCGKTFPDRYSCKVHNKTHEGEKCFKCDVCPYASTTQRHLKTHMLKHTDEKPFLCDMCDQSFRQKQLLRRHQNLYHNPNYVPKPPKEKTHCCHECQRMFAHKGNLIRHLAVHDPESGHHERALALKIGRQRKVQFIDGKPTRDLRVVDSADPEHLMKLGLTNKELKRGELVTVADGNGQQYVVLEVIQLEDGTEQQVAVVAPGEFMDVDEPAYSTEEDEEEEEEEEEDEEEEGEDRSFVVKAPMVSQSIKLEKEVDTCFGFDEEDEDPDDVNYTDKVVLRLV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00177438;
90% Identity: iTF_01026640;
80% Identity: -