Pneb042616.1
Basic Information
- Insect
- Polia nebulosa
- Gene Symbol
- LZTR1
- Assembly
- GCA_951329385.1
- Location
- OX589606.1:8709661-8734080[-]
Transcription Factor Domain
- TF Family
- BTB
- Domain
- zf-C2H2|ZBTB
- PFAM
- PF00651
- TF Group
- Zinc-Coordinating Group
- Description
- The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 2e-07 0.00019 23.4 0.0 54 109 55 121 44 122 0.87 2 4 8.8 8.2e+03 -1.2 0.0 78 107 122 151 118 153 0.82 3 4 2.1e-17 2e-14 55.6 0.0 9 97 218 306 213 321 0.85 4 4 0.52 4.8e+02 2.8 0.0 77 107 320 350 309 353 0.81
Sequence Information
- Coding Sequence
- ATGCAACACAGATGGAAAAACGCTTGGCAGATTGCTTTACAGTCTCTctcatttattttcttgtttcaAAGGGAAGCTCGAGATGAATTAACAAAACGCATCGCCGCCGGCGAGGAGGAAGCTTCCGAAGTGTGCTCGTACAAGACACCGCCCCAACTGTGCGTGTTGCTGCCTGAAGCGACGCCCGAGTCGTTCAACATGGTGCTCAACTACATATACACCGACAGAATAGACCCCACTGAGAAAGACGAGGACCCGGCGTCCCCGGCCACCGTGCTGCTGGTGATGGCGGTGCTGCGCCTCGCTCTCCGCCTCAACATCCCACGCTTACGTGGCCTGTGCGCGCGCTTCCTGCGAGCCAACCTCTGCTACGGCAACGTGCTGCAAGCGTTGCACGCCGCCCACCACGCCAACCTCACGTGcatcaaggagtactgcttGAGATTTGTGGTAAAAGACTATAACTTCACACCGATAGTGATGTCGAAAGAGTTCGAGGAGATGGAACAAAGTTTGATGGTGGAGGTGATCCGTCGACGGCAGCAGCCGCCGCCCAAGCAAACCAACGCGGTGGTACAGCAGGAGTACGATGAAGAGATCATTGgAACCACTCTGGAGCAGGACATGTGCGTGCTGCTGGGCGGCGGCGCGGAGCTGTCGGACGTGCGCCTGCGCGTGGGCGCGGCACAGCGGCCGGCGCACCGCTCGGTGCTGGCGGCGCGCGCGGCCTACTTCGAGGCCATGTTCCGCTCCTTCTCGCCGCACGACAACATCGTCAATATACAAATCTGCGACACGGTGCCGTCGGAGGAGGCGTTCGACTCGCTGCTGCGGTACATCTACTACGGTGACACCAACATGCCAACGGAAGACTCGCTGTATTTGTTCCAAGCGCCGATATACTATGGTTTCACAAATAACCGGCTTCAAGTATTCTGCAAGCACAACTTGCAGAGCAACGTGTCCCCGGAGAACGTGCTCGCTATCCTGCAAGCCGCGGACCGCATGCGCGCCACGGACATCAAGGAGTACGCGCTCAAGATGATCGTGCATCACTTCGGCCTTGTCGCGAGGCAAGACGCCATCAAGAACTTGGCGCAACCACTCCTGGTGGACATCATCTGGGCCTTAGCTGAGGAGCCCCACTTCGACTCGCCTCTCCCGGTGCAGCCGAGGTCATTGCCctcgtcatcatcagctgacACGCTCACAGAGGACCCTGAGTACTCTCGACATAGATGTGGGAAGTCGTAG
- Protein Sequence
- MQHRWKNAWQIALQSLSFIFLFQREARDELTKRIAAGEEEASEVCSYKTPPQLCVLLPEATPESFNMVLNYIYTDRIDPTEKDEDPASPATVLLVMAVLRLALRLNIPRLRGLCARFLRANLCYGNVLQALHAAHHANLTCIKEYCLRFVVKDYNFTPIVMSKEFEEMEQSLMVEVIRRRQQPPPKQTNAVVQQEYDEEIIGTTLEQDMCVLLGGGAELSDVRLRVGAAQRPAHRSVLAARAAYFEAMFRSFSPHDNIVNIQICDTVPSEEAFDSLLRYIYYGDTNMPTEDSLYLFQAPIYYGFTNNRLQVFCKHNLQSNVSPENVLAILQAADRMRATDIKEYALKMIVHHFGLVARQDAIKNLAQPLLVDIIWALAEEPHFDSPLPVQPRSLPSSSSADTLTEDPEYSRHRCGKS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00041912; iTF_01085538; iTF_01440239; iTF_00835716;
- 90% Identity
- iTF_01085538;
- 80% Identity
- -