Basic Information

Gene Symbol
-
Assembly
GCA_963082735.1
Location
OY720432.1:76888614-76921344[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 19 4.2e-05 0.01 17.9 2.1 1 23 432 454 432 454 0.96
2 19 1.1e-05 0.0027 19.7 0.4 1 23 460 482 460 482 0.97
3 19 2.1e-05 0.0052 18.8 0.5 1 23 488 510 488 510 0.98
4 19 1.8e-05 0.0044 19.0 3.1 1 23 516 538 516 538 0.97
5 19 4.1e-05 0.01 17.9 4.7 1 23 544 566 544 566 0.99
6 19 7.4e-05 0.018 17.1 5.7 1 23 572 594 572 594 0.97
7 19 2.1e-07 5.1e-05 25.1 4.3 1 23 600 622 600 622 0.98
8 19 1.3e-07 3.2e-05 25.8 2.4 1 23 628 650 628 650 0.97
9 19 0.00017 0.043 15.9 5.7 1 23 656 678 656 678 0.97
10 19 2.2e-05 0.0054 18.8 6.5 1 23 684 706 684 706 0.98
11 19 3.7e-06 0.00092 21.2 4.5 1 23 712 734 712 734 0.98
12 19 8.6e-06 0.0021 20.0 8.1 1 23 740 762 740 762 0.98
13 19 2.1e-06 0.00052 22.0 7.9 1 23 768 790 768 790 0.98
14 19 7.8e-07 0.00019 23.3 7.7 1 23 796 818 796 818 0.98
15 19 0.00024 0.061 15.5 9.5 1 23 824 847 824 847 0.95
16 19 0.00021 0.051 15.7 0.5 1 23 853 875 853 875 0.97
17 19 3 7.5e+02 2.6 1.8 1 10 885 894 885 900 0.92
18 19 2.2 5.5e+02 3.0 1.6 11 23 904 916 901 916 0.92
19 19 7.6e-06 0.0019 20.2 1.7 1 23 922 945 922 945 0.96

Sequence Information

Coding Sequence
ATGAATTCGGATCATACAACAGCTCCTGGCGAGTCGTCATCAAACCCGAATGACTCTCAACAAAGTCGGCATTCGCCGCAGCAGgctcagcaacaacaacaacaacagcagcagcagcagcaacaccatcaacatcaacaacagcaacagcagcagcagcaacaacagcagcagcagcagcagcagcaactcgCTCACCAGCGACATCCACAACAATTGAACGAACTTGGAAAATATTGGGTTGTTACCAATCTATTTCAGGGTCCAGGTCAGCCGCCATACAATATTGGTGTAACACCAACAACCTCAGCAGTTCCTACACTACCGCCTCCAATATCATCTCATTCAAGCGCCTCAGCAACAAAATCAGGAAACTCTAAGCAACAACAGCAAGATCAACTAGCACCCAACTCGCACACACAATCACCAGCACACATAGTATCATCGGTCGGTGCAACATCTTTACAAATACCCAATCCAATGATAACAAATACATCGATGAATCAGCAACAGCTTCCGAATGGCACCATTATTGCAGCACCACGTCATCCGGATTCTTTACACGTCCATGGAACGATGTCCTCCGACGATAATCGACACGTCTCACACGGTATGCAAGACATAAAGGAGGAGAAACCTTTCGCAAATGGCAAACAGAATAATCACATGGCTCATGTTAATCCAGCATCTTCCGTTTCGTCGAAAATGAATTCTGGCAGTGGTGGCAACAATGTGCAATCTGTCGAACCAGGTGGTGGCAGTGGTGGTGGACAACAAATGGTTAACAAATTGCAAACGGGCGGTGGTCCAACTGGAACCGTTGGTGGCGGTGGCGGAGGAAATGAACAACAAGAGTTGGTAAGCGGTAAACCGCCACACGGCGTTGAAATGTACAAAGTCAATATTGAAGATTTGAGTCAATTTCTATCATATCACGAGGTCTTTGGCAAGATCCATGGCGAAGTAATAAATCAACAGCAAATATCATCGCACACGGTAACGCATCCTACTACGAATGTATCAACCTCAAATGCTGGTGGCAATACCTCTGTGAGTGGTACTGTTACTGGTTCACTACCTCCACCCCCGCCACCGTCGACTAATGGCAATTCGATAGTGTCAACCAACAGCCTTACCAGTTCCGGGACTGGTGCACAAGCAGTTCCGCCACCAGGTGGTGGGCCCACTGTTCCCGGTGATCTGATACTGCCTAAAATGGAGAATCAAGGGATGGGTGTAGATCAGAATACCCCTCTGTTGGCACCCGATGGAACGCCCATAATGGGTGGTACGCATATCTGTGACATTTGCGGCAAAATGTTCCAATTTCGCTATCAACTAATTGTTCATCGTCGCTATCATAGTGAACGTAAGCCATTCAATTGCCAAGTATGCGGACAGGGATTTACAACGTCGCAAGATCTCACCCGTCACGGTAAGATCCATATTGGTGGGCCAATGTTCACGTGTGTCATTTGCTTCAATGTGTTTGCCAACAACGCCAGCCTGGAGCGGCATATGAAACGTCATTCAACCGACAAGCCATTCGCGTGCACCATATGCCAGAAGACATTTGCCCGCAAAGAGCACTTGGACAACCATTTTCGCAGTCATACGGGCGAGACGCCATTCCGTTGTCAGTATTGTGCGAAAACGTTTACGCGAAAGGAACACATGGTGAATCATGTGCGCAAGCATACCGGAGAGACGCCGCATCGTTGCGATATTTGTAAGAAATCTTTTACGCGGAAAGAGCACTATGTAAACCATTACATGTGGCATACAGGTCAGACACCGCACCAGTGCGATATATGTGGGAAGAAGTACACACGGAAGGAGCACCTAGCCAATCATATGCGGTCCCATACGAACGATACGCCATTCAGATGTGAGATATGTGGCAAAAGTTTCAGCCGAAAGGAACACTTTACCAATCACATCTTATGGCATACAGGAGAAACCCCTCATCGCTGTGATTTCTGTGCGAAGACGTTCACCAGGAAGGAGCACCTATTGAATCATGTCCGCCAACATACGGGTGAGTCACCACATCGCTGCACCTATTGCTTGAAGACCTTCACTCGTAAGGAACACCTAGTGAATCACATTCGTCAACACACAGGCGAGACCCCCTTCAAGTGCACCTACTGTACCAAGGCGTTTACTCGAAAGGATCATATGGTTAATCACATCCGTCAACACACTGGAGAGTCACCGCATAAATGCACCTACTGCACGAAAACCTTCACGAGGAAAGAACATCTGACCAATCATGTGCGCCAACATACGGGTGAGTCGCCTCATCGTTGCACCTACtgcaaaaaaacatttacacgCAAGGAACACCTAACGAATCACATCCGGTTGCATACAGGCGATTCGCCCCACAAATGCGAATACTGCCAAAAGACGTTCACACGCAAGGAGCACTTGAACAACCACATGCGACAACACTCGAGTGACAACCCACACTGTTGTAATGTGTGCAACAAGCCGTTCACACGCAAGGAGCATTTGATCAATCATATGTCGCGCTGTCACACTGGGGATCGACCGTTTGCATGTGAGACATGCGGCAAAAGTTTCCCACTGAAAGGCAATTTACTCTTCCATCAACGCAGTCACACCAAGGGTCAAGAGTGTGAGCGTCCATTTTCGTGTGAAAAATGTCCCAAGAACTTCATATGCAAAGATCCTTTGCATATTGCATCGTCCTCAGGTCATCTGGTATCGCATATGCGTTCGCATTCAGGTGAGAAACCACATGCGTGCACTATGTGTAGTAAGGCATTTGTAGAGAGAGGGAATCTCAAGCGTCACATGAAAATGAATCATCCAGATGCAGTTATGCCGCCACCTCCGACACCGATTCCGGGTATTTTAACGCAAATCAAACAGGAGATCAATCCGATAATAAttCCTCATCAACCTCCAACTATGCACACAATACAGCAAATCACTTCAACTGCAGGCAGCTCAAGTGCAAATAACCCTGGGAATCCAGCCCTTCTGGCGCCCGGTCTTGTACCAATGGTAACGTCTACTATAACTTCACATATTAGTCAAAAGCAGCAATCccatcaacagcaacagcagcagcaacaccaacatcaacagcaattgcagcagcaacaacagctattACAGTTATCCATTCAACAGGCAGCTCAGCACCAGCAGGCTGAACATcgacagcaacagcaacaacaacagcagcaacaacatcagcagcaacaacaaagccatcaacaacaccaacagcagcaacaacaacagcagcaacaacaagctCAACAACAATCACAACATCAACAGCCACAACCGCCACCAGTGCCGATAGCTCTCATTGGAGCGGATCCCTCAGCGATAGCACGCGCTGCTATGCAATTACAACATTTGCCAACGAATGTCGAACAGCATCCAGTCGTATATTAA
Protein Sequence
MNSDHTTAPGESSSNPNDSQQSRHSPQQAQQQQQQQQQQQQHHQHQQQQQQQQQQQQQQQQQQLAHQRHPQQLNELGKYWVVTNLFQGPGQPPYNIGVTPTTSAVPTLPPPISSHSSASATKSGNSKQQQQDQLAPNSHTQSPAHIVSSVGATSLQIPNPMITNTSMNQQQLPNGTIIAAPRHPDSLHVHGTMSSDDNRHVSHGMQDIKEEKPFANGKQNNHMAHVNPASSVSSKMNSGSGGNNVQSVEPGGGSGGGQQMVNKLQTGGGPTGTVGGGGGGNEQQELVSGKPPHGVEMYKVNIEDLSQFLSYHEVFGKIHGEVINQQQISSHTVTHPTTNVSTSNAGGNTSVSGTVTGSLPPPPPPSTNGNSIVSTNSLTSSGTGAQAVPPPGGGPTVPGDLILPKMENQGMGVDQNTPLLAPDGTPIMGGTHICDICGKMFQFRYQLIVHRRYHSERKPFNCQVCGQGFTTSQDLTRHGKIHIGGPMFTCVICFNVFANNASLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDICGKKYTRKEHLANHMRSHTNDTPFRCEICGKSFSRKEHFTNHILWHTGETPHRCDFCAKTFTRKEHLLNHVRQHTGESPHRCTYCLKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHIRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGESPHRCTYCKKTFTRKEHLTNHIRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFACETCGKSFPLKGNLLFHQRSHTKGQECERPFSCEKCPKNFICKDPLHIASSSGHLVSHMRSHSGEKPHACTMCSKAFVERGNLKRHMKMNHPDAVMPPPPTPIPGILTQIKQEINPIIIPHQPPTMHTIQQITSTAGSSSANNPGNPALLAPGLVPMVTSTITSHISQKQQSHQQQQQQQHQHQQQLQQQQQLLQLSIQQAAQHQQAEHRQQQQQQQQQQHQQQQQSHQQHQQQQQQQQQQQAQQQSQHQQPQPPPVPIALIGADPSAIARAAMQLQHLPTNVEQHPVVY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00426545;
90% Identity
iTF_00991990;
80% Identity
-