Parg012423.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Plebejus argus
Gene Symbol
IBTK
Assembly
GCA_905404155.1
Location
FR989946.1:9212142-9225696[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 2.5e-16 9.9e-14 51.9 0.0 8 79 546 614 539 622 0.89
2 3 8.7e-11 3.4e-08 34.0 0.0 9 105 726 826 720 831 0.76
3 3 2.9 1.1e+03 0.2 0.2 79 106 832 859 828 862 0.88

Sequence Information

Coding Sequence
ATGAGTAAGATAGAAGTGGATTGCACAAAGAAATGCAACTCTCGCCTTCATGGCCAGGCGTTGACAAGTGCCATTACCAAGAGATCTGTCAGTGATGAGTCGCTCGCAAGCTTCATCAAAAGCACCTGTGCCAATTTTGCTAAAGCTTTTGATTTTGAGGGTCGTACTGCTCTGCATATGACTGCATCACGAGGTAGAAATGGGCTAATGCAATGGCTTATACGTCACTCCTCTGACGCTTTTATCAATGCACGCGACCGGGAGTCAGGGTACACTCCATTGCACAGAAGTATATTTTATGGGCAAATTCACTCTGCTGTCGCTTTGATGAAACTAGGAGTAAACACCGATATAGTAGACAAGGATGACTACAAGGCGCTAGAACATGCTATGCTGGATAAACATTACATGTGGAAAGCTGACGGACCGCAGCCGTGTGATGCGTACGTCTGGGGGAGCAACTCCAACTATACTCTAGGCACGGGCTCCCATCAGCCTCGACAGATACCTGAGTTGCTGAGCTGCTTTAGTCGCACCAATGCGAATGTTAAACAGGTGTGCCTCGGCAAATTCCACAGTATCTGGGTGTGCGACGGGGACGTATACTGTGCTGGTCAACCTGCACGCGCGGGCGGGCCGCACGCCACCGCCCTCCGGCCCATACTGCTGCGTCTGACGGAGCCCTGCGCCGAAGTCGCCATTACCCTGACGTCCACGGTGTTCCTGATGCAGAGTGGCGCAGTCCTCCAATACTCCCTCAATAACACGGACACAGTATCATCCACCAAGAACCCCACCACAATTAAGTTGCCGTCCGTCAAGCCGCTGATCAAGCTATCGTGCCCGCTCGGCGTGCGTACGGGACGCTCGCACGCGGTCGTGTGGAACGAACGAGCTATATACACGTGGGGACAAAATATGGGACAGTTGGGACATCAGCTGGAAGAGAAAATTGTCCCTGGGCCTAAGAGGGTGGCGATATCACTAAACATCAAGGAGGAAGCGACCATCCAACTGGTGGACGCGTGCGACGCCGCCACAGTGCTGACCACCAGCCGCGGCGACGTGTACCTGCTGCACAAGTACCTCGTCAAGAAGATCGCCGTCAAACAAATAAACATACGCCAAGTGTGTGTAGAGGGTAAAGTGAGTGAGCAGGGCGCGTACTCTCGCGTCACCGTGCTGCTGCTGACCAACGTGGGACAGCTCATGATATGGCAGGACACCACGCAGCGGCTTACTAGATGCGTCTTCGGCCTAAACCACCAAGTCGACGTAACACACGTCGCTCTAACTCACGACGCACTTTACTTCACGACAAAATACGGTGAGGCGTTCATTGGTCACATATCCCGCAAGACCACGCCCCCCGCGCCGCAGCCAATCAGGAAAGAGAGGGAGAGAGACAACAAATCGGCCCTAGTCAAGTTTTTAGAGAAGGACGACTGTACTTCTGTGCGCATCACCAAGATACCGAATGTACACCGTGCCACTGCGATTGTAGTTGATGGCGAGGGGTTGAATTTTGCGTGTTTGCAGATGAAGCCGACCTGCGGTCTGACGTCACTCCCGGATTTATCACCGTCGAGTCTCGCGAAGCACATGGCAACGCTGATGGAGACAGCCGTCGACGATGATATACTGCACGATGTTGTGTTCCAGGTCGGAACCAAACTATTCCCGGCGCACATATTCATCGTAGCGTCAAGCAGTGAATACCTATACAAGTTATACCAGGATGCACGGACGGACGGCAAGACAACAGTCGTATTAGATAACGTGCACCCAGATGTATTTGAGAGGATTCTCAGATATATGTATACGGGTACTTGTGATGTAGCCGAGTTGGGCCCGTGCGGACTCAAGATAAGAAAGGAAGATCTGAGTGACTTGAAAAAGAAAGAGAAGGAAGATGATGAGACGGAGTTTATAGAGAACGCATCCGAGATATCCGCATTCGAGGTGTACAAGCGGGACAAGCGCCGGCGGGCCCCGCCGCCGACCGCTCGCACGCTGGACGCGGTCAAGTGCGTACAGGCCGCCGCCAAGCGTCTACACGTGATGTCGCTGCACAAGCTGCTAGACAAGTTCTATTACCGAGACGGCATAGTATACGTCAAGGAGAGTGCCACATACACCAAGACCCCGCTGACATGGAACCGAGAGAGTTACCCGGAGCTGGTCGACACGAATGTGTGCTCAAAGGACGGTGTTCTGATACCAGCGCATAAGTGTGTGTTGGCGGCCAGGCTGGAGTATTTCCATGGCATGTTCATACATTCCTGGACTGAGAGCAAAATATTATCAACAGTTACTCTGCCTGTAAACCACGGTATTCTGCTGCCCGTAATCGATTTTCTCTACACCGATAAATGCCCAGAAGTCGAAACATCAGATAGCATCGACTTCATATGCAGCATGCTTATTGTATCCGATCAGTTGTTTATATGTCGACTGCGAGAAATGTGTGAGATTGCTCTAGCTAACTTGATTACATTGAAAAACTGCACAGAGTTGTGCCAATTTGCACACACATACAACGCTACACAGCTTAAACAATGCTGCATGGAATTCATAGCTCTAAACATAAACAATATCCTTGAAAACCGATCTTTGGACTTACTAGAAGAGGTTTTACTGGAAGACATATCAAAATATTATTGCAAATTCAATCCAATAATGTCTTCGAGAGTTATCACTCCATTTTTCAACTCTCCTTCAGATGATGTGATTGACGAACATGTTAAAATGTGTCCGGTAGATCTAGATTATGTTGATGAAGAATTTAAGAAAGACATAAATATTGGTGAAAAAGAAATTAGTAAAAAGAAGAAGCAAAAGAAAATTGAGTATACTGAAAGTGAAAAGGCAAGAATGAGGTATGAATCAGTAAGTTCTGTTACATCTTTAGATTTATCTAATGATACTTCTGGAGATGTGACTCTATCTCTCAGTTCCATATCTACTGAGGAAAAAGATAAGACAAAAGGAAAAGATACAGAGAAATGGACAAAGATCCCGACGCAACAGCAGAAGCAGCAGAAAGTTGTACAAGCTCGGTTAAAAGCTATCTCATCCGCTAAAGAAATAATGAATGAAACACCCACGAATTCATTTACAAAACTCGTCAAGAATAACTCTAACAGTGCCATATCTGAACCCGTAACCCCCACTAGTTCCAACATGGCCTCCCCAAAAGATACTAAGGCCTGGGGCCAGGGAAATCTCATAATCAATCATGTAGGTCCAAAGTTATCGCAGAAACAAAGAAAGAAATTGGCGTCAGAAAATGAGAATCCCGCAATCACTTTGGACGATTATTTAGCTGATAAACTAACTATAGGCAGCCCACCTGACAAACCCAAAAACCCCTGGAAGATCTGTGAGCCTCCCGTTGCAAGCAGTAGCCCAAATAAATCGAAATCTATTGAATTCAATAAAATACTTGCTGACCAGAAAAAGCAGAAGGATGACTTCTCTAGAATAATGACAAAACCTCTTGCACTTACTCAGCTTGAAGACAAAGCCATAGAAGAATTGGAGAGATTCTATAATATACATGAAATTGATGATGAGCTGATCAGCGTGAGAAGAATTGAGCTGCAGGTGTCTTCACCACAATGGATCAACACTGCCTCAAAGTGA
Protein Sequence
MSKIEVDCTKKCNSRLHGQALTSAITKRSVSDESLASFIKSTCANFAKAFDFEGRTALHMTASRGRNGLMQWLIRHSSDAFINARDRESGYTPLHRSIFYGQIHSAVALMKLGVNTDIVDKDDYKALEHAMLDKHYMWKADGPQPCDAYVWGSNSNYTLGTGSHQPRQIPELLSCFSRTNANVKQVCLGKFHSIWVCDGDVYCAGQPARAGGPHATALRPILLRLTEPCAEVAITLTSTVFLMQSGAVLQYSLNNTDTVSSTKNPTTIKLPSVKPLIKLSCPLGVRTGRSHAVVWNERAIYTWGQNMGQLGHQLEEKIVPGPKRVAISLNIKEEATIQLVDACDAATVLTTSRGDVYLLHKYLVKKIAVKQINIRQVCVEGKVSEQGAYSRVTVLLLTNVGQLMIWQDTTQRLTRCVFGLNHQVDVTHVALTHDALYFTTKYGEAFIGHISRKTTPPAPQPIRKERERDNKSALVKFLEKDDCTSVRITKIPNVHRATAIVVDGEGLNFACLQMKPTCGLTSLPDLSPSSLAKHMATLMETAVDDDILHDVVFQVGTKLFPAHIFIVASSSEYLYKLYQDARTDGKTTVVLDNVHPDVFERILRYMYTGTCDVAELGPCGLKIRKEDLSDLKKKEKEDDETEFIENASEISAFEVYKRDKRRRAPPPTARTLDAVKCVQAAAKRLHVMSLHKLLDKFYYRDGIVYVKESATYTKTPLTWNRESYPELVDTNVCSKDGVLIPAHKCVLAARLEYFHGMFIHSWTESKILSTVTLPVNHGILLPVIDFLYTDKCPEVETSDSIDFICSMLIVSDQLFICRLREMCEIALANLITLKNCTELCQFAHTYNATQLKQCCMEFIALNINNILENRSLDLLEEVLLEDISKYYCKFNPIMSSRVITPFFNSPSDDVIDEHVKMCPVDLDYVDEEFKKDINIGEKEISKKKKQKKIEYTESEKARMRYESVSSVTSLDLSNDTSGDVTLSLSSISTEEKDKTKGKDTEKWTKIPTQQQKQQKVVQARLKAISSAKEIMNETPTNSFTKLVKNNSNSAISEPVTPTSSNMASPKDTKAWGQGNLIINHVGPKLSQKQRKKLASENENPAITLDDYLADKLTIGSPPDKPKNPWKICEPPVASSSPNKSKSIEFNKILADQKKQKDDFSRIMTKPLALTQLEDKAIEELERFYNIHEIDDELISVRRIELQVSSPQWINTASK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01178756;
90% Identity
iTF_01248322;
80% Identity
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