Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.0034 4.9 7.3 0.1 20 44 89 113 82 118 0.87

2 7 0.0019 2.7 8.1 0.3 21 46 118 143 115 149 0.87

3 7 0.0064 9.2 6.4 0.1 21 44 146 169 143 174 0.90

4 7 0.08 1.1e+02 2.9 0.1 21 44 174 197 171 206 0.85

5 7 0.049 71 3.6 0.2 22 44 203 225 200 229 0.90

6 7 0.006 8.5 6.5 0.1 21 44 230 253 226 257 0.90

7 7 0.043 62 3.8 0.1 21 49 258 286 255 290 0.85

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.0034	4.9	7.3	0.1	20	44	89	113	82	118	0.87
2	7	0.0019	2.7	8.1	0.3	21	46	118	143	115	149	0.87
3	7	0.0064	9.2	6.4	0.1	21	44	146	169	143	174	0.90
4	7	0.08	1.1e+02	2.9	0.1	21	44	174	197	171	206	0.85
5	7	0.049	71	3.6	0.2	22	44	203	225	200	229	0.90
6	7	0.006	8.5	6.5	0.1	21	44	230	253	226	257	0.90
7	7	0.043	62	3.8	0.1	21	49	258	286	255	290	0.85

Coding Sequence: ATGGACACGTTCTCATGGAAAGAAGAGGATGATTTCCATTTGGCTATACTGCAAGCAATGAGGGTACCGGTGTATAAAAATGAATGGTGTAATCCTGAGGAAATGTTGGAAACTTCATACAATGAAGTTCAAGTCGAACCAGTTGAAAGTCATTTTGTTGCTGAAATACATGAAGATCGAGATCGAGACAAAGATGAACATGATGAAGACAAACGTCaaagttttaatgaaaatgataaattgCATCAGCACGAATCTACTCAAGTTGGAGAAAAACCGTATGAATGCCAAATATGTCAAAAGAAATTTACTCAAAGCAGCACCTTGAAGTCGCATATTCTAACTCATACTGGAGAAAAACCGTATGAATGCCAAATATGCCAAAAGAAATTTCGTCAAAATCCCCATTTGCAACAACATATGCAAACTCATACTGGAGAAAAACCGTATGAATGCCAAATCTGTCAAAAGAAATTTAGTCAAAGCAGCACATTGAAGTCGCATATTCTAACTCATACTGGAGAGAAACCGTATGAATGCCAAATATGTCAAAAGAAATTTAGTCATAGCAGCACCTTGAAGTTGCATATTCTAACTCATACTGGAGATAAACCGTATGAATGCCAAATATGTCAAATGAAATTTCGTCGAGATCAACATTTGCAACAACATATGCCAACTCATACTGGAGAAAAACCGTATGAATGCCAAATATGTCAAAAGAAATTTAGTCAAAGCAGCAGCTTGAAGTCGCATATTCTAACTCATACTGGAGAAAAACCGTATGAATGCCAAATATGCCAAAAGAAATTTACTCGAAACAGTACCTTGAAGAACCATATGAAAAACAACCACCCTGGTAAGGATGCGAGCAGTTCATTAGATAATGAACGTAGATCCGTTGAAATGGAAATGTTTCCATACATGAAGatgtattttctttaa
Protein Sequence: MDTFSWKEEDDFHLAILQAMRVPVYKNEWCNPEEMLETSYNEVQVEPVESHFVAEIHEDRDRDKDEHDEDKRQSFNENDKLHQHESTQVGEKPYECQICQKKFTQSSTLKSHILTHTGEKPYECQICQKKFRQNPHLQQHMQTHTGEKPYECQICQKKFSQSSTLKSHILTHTGEKPYECQICQKKFSHSSTLKLHILTHTGDKPYECQICQMKFRRDQHLQQHMPTHTGEKPYECQICQKKFSQSSSLKSHILTHTGEKPYECQICQKKFTRNSTLKNHMKNNHPGKDASSSLDNERRSVEMEMFPYMKMYFL

Sequence clustering based on sequence similarity using MMseqs2