Pcyl007425.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Platypus cylindrus
Gene Symbol
Baz2b
Assembly
GCA_949748235.1
Location
OX456489.1:9300204-9316408[+]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 2.2e-14 5.5e-11 41.9 0.0 5 73 775 844 772 848 0.90
2 2 2.6 6.5e+03 -3.2 0.0 51 72 1798 1818 1794 1819 0.89

Sequence Information

Coding Sequence
ATGGACAAAGAAAATGGTAAAGTCAACGAAGGTACATCTGGAGCCAGTAGTAAACTTCAAGATCAAACATCATCAATATTGGATGCAGCTAATTTATTTGGAgCTTATTGGCCACGAAGTGATGCAGCAACTAATCTATTTGGAAGCAGTTTCGGTTTATCACCACATGCCGCTGCAGCTGCTTTACCATTTGGAATTCTaccaacagcagcagcaggaggAACTACAGCAGCAGTTACTAGTCAATCATCATCAGGACGTAATAGCGGTGGAGGAGGAGGAAGCTcaacaccatcatcatcatcagcaggAGGTTTATCACATAATTTATCAACAATATCATCTTCATCAAACGCACAATCTGCTGGATCAACATCATCCGCATCGGCCACATCCTCATCATcggctgctgttgctgctgcagCAGCTGCAGCTGCTTATAGTAATGCAGCTTATTCGAATACATTATCAGTGGCTGCCAGTCAAGCTGCAAGTCTTGGAATGCCAGCAGCAAGTGCAGCATGGTGGTCGATGGCATCCCATTTAGCCGCCCAAGAATATATACAACGTTTACAAGCAACAACGGGTCTAAATTTTCCATTGGGTGCTGCTGCCGATCCATATGGCACATTGGCATTGGCAAATTTAACAGCACTCGGTGCTGGTGGTGTTGGTCTTGGTGGCGGTGGTGCTAGTGGTGCCGGTAGTGGACATCACAAATCGAAAAATTCATCATCGAAAAACTCTTCACGTAGTAATTGTAAAGATAAATCTGGAACGAATAGACGGAATGATAGTAgcgatcatcatcatcatcaccatcaacAGCAACAGCATCATCATTACAATCAACATAAAACTAATTCGTCCGCATCGTCTGTTAATTACAATAAATCCTCATCAACTAATTCACTGAAATATTCATCAGCATCCGGTCTAACAATCCAACCGACAATGAAATTGCCACCATCATCAAacaataataatagacagaaaaataatagcaataacagCAGCAGTAACAGTGTTGCCAATAGTTCGAGTGGTGTTGTGAATTCGTCAATATCATCGTCAATATTTTCCAATCCACTTAGTTTGGCCAGTACAAATACGAATAGTATACATCAATCAGATAAATATCTGGGTACTATTTCAATACCGATGAATAATAGCCATAGTAGTACTACATCAACAACATCagcaactaataataattctggAATTGTTAATAGTTACAGCAACAGTAATTCACCACAATTACCACAAAGTATTTTAagTGATCCTAATTCAATTTTGGGTGGTGTTAGGTTGCCGCCTGACACCGAAATCATCAAATATACATCGTCGATTGTTGGCCCGAAAATTCCTGGTACAACAAACCGTGGACGAAAGAAGACAATATCATTGGATCCACCACCATCTGACGAAGACATGTTGGCTGGTATTCCATTATCGGATCGTGTTGAAGTAATCAAATTACCAACAACCAATGGAAGTATAAATGAAACATCATCGACTAGTGAAGCACCACTTAATCTATCCCTTAAATCGAATTGGTCTTCCATCAGTGggaatagcaataataataatattaatcaaaataataatggcTCATCAACGCATTTAAATTCATTGAGCAATATGAGTGTTAATATTGGAACTGAACGTATTGGAACAACTGATCGCATATCTCGTCGTAAACCTGGTCCAAGACCACGTCGTGTAGTTCCAATGGAAtgtacaacaacaacaacgccAGCTGCTCCTGCTCAACCACCAATTTTAAATATCCCATTTAATCAATTCAATTTCACAACTGGATTGGATTCACCACGACCGCCAAGTCGTAGTGAGGGTTCCGATGGTGGCAGTTCAACGTCATCAACATCGGCTATTGGTGGTAGTGGCGGTGGTAGTGGTAGTGGTACACTGAATCATAGTAATAAGGAGGGTCGTCCAAGGAATTTAGGTCGGGGCGTTAGTAAACCGAAAAAGAATACAGTTGCATCATTGTTGGCACAAAGTAGAGCGTTAGGAATTAAACCAGTTCCAATGTTGGATCCATCAAATACGTCAACAATGAATCAACAGATGCAATTGTTACGTTCAAATATAATGGATGCTCAACGTTATATATCGGAAGTTGGTGGTGATGAGAAAgcgttaaataaatttctacaAGAGAAATTTAAAGGGCCACTGAGTGATGGTAGTACAGTAGATGCATCCGATTCAGATAATTTTACTGATTCGAATCATACTGATTCAGAACTTGAGACTGAACAAGTACCTTTGATGAAAAGGCCAAAACATTACGATGAACGATTGTTACGTGTGCCATTAGAAAAAGGTTGGAGAAGAGAAACTTTAATACGAGGCGTAACGAAAACTGGTGGAATTAAGGGGGATGTAACGTATTCAGCACCCGaatcaacaaataaatttaagcaAATGTCAGATGTCACACAGTATTTAGAATATCAAAAAAATCTAGAATtatcaaaagaaaattttacgtttagtTGTCGAGCAATTATCGGTGATTATCTACAGCCCATACCTCCAGAGATGCAGACTGATGGTactgaatatatttttttgactGAAGAGGATGTTACTAAGAGACTGGACGAATTAAAAGCAGCAATGCGTACAAGTATACCAGTTGAACAACGAATTGAAATGGCGAAAAAGCAGCAAGCTGCCCGTGCCGCAGCCCGTTTGGATCGCGAACAACAACGATTAAATAAGGAATTGGAAAGGAATGAACGACAAGAGGCGGCTAGACGTGAAAAAGAAGCAAGAACACAACAAATGTTGGAGGCTAAAAGAAAACGCCAGGAGGagttagaaaaacaaaaacaagaaGAACAACAAAGAAAGCAGCAGgAAAGGGAATTGAAACGACAACAAGCGGCCATGTTGAAAGAACAAATTTACATACAGGAGGTCAATAAACAACGAGAAATGCTCTACACTGTTGAGTTGGAAAAAGAACGTCGAAGACAACATTTGGCATTAATAAAAGCAATGGAAAATCGTCGTAAACTCGAAGAAAAGGAACGTCGAAAACAACAATTACTAGCCGAAAAACAGGCGAATCGTGAAAAGAAACTAGAACAACGTAAAGTtgatttagaaattttagCTGAATTACGTAAACCGTGTGAAGATTTAGAATTGAATCAAAATGATTTACCAGAATATGAACGAATACCTGGTGTGAAATTGTGTGGTAAAGCATTTGCCGATACGTTAATGGTATTTGAGTTTTTGCATAATTTTGGTGAAGTACTTGGTTTCGATATGGAGTCATTACCAACATTGGAGTCATTACAACAAGCATTAATGCCAAATGAACATACATATGAAGCGGAAGAGGAATTATTCTCAGTAATGACACATTTATTAGTTTGTGCAATAGAAGATCCTGGCATACCGAATCCAGCACGTCATACAACAATTTTAGGTCAAAGTCTACGACAGGCCGATATAACACATACGAATTTATCAGAAATTttacgtatttatttatatgcaaATGCAACGGGTGAAGTGAAAGCATTAACTGGTGTACATTTCGAAAGGGATCGTGAGAAACGTGTGGCCGATCATCATCAGACCGATGATGAAATGCAACAAACACTAAATGGAAAAAATGCAcattattatgaattattaCATGAGAATCCAACATATAAAATGTCAGATTTATTACGCGATAAACCATTTATCGCATTAACGCCAACTGATAAAGCGGCCATTCTAGCATTTATCTGTAACGAATTGTTACAAAATAAAACCGTACTTAGACAAATTGAAAACTCTTTGGAAAATATGATTCAACATAAAAGAGACAAATGGTTGTTGGATCAAAAAATTCGTAAATTACGTGTTGTgcataatagaaaaatacgTAATGAGGCCGCATTAGAGAAATGCCATATGATTAAATGTAATAATGATAGTGGTGTAGATGATGCTGTCAGTGCTGCTGGTGGAAGTGGtcatggtggtggtggtgctagCTTGGATTCACCACATACCTCTCATAAAGATGATTTACTTGATGACGATGTTGTCGATCATGAAATGAGTGACAATGAAAGTGTCGGAACACAAccggaagaagaagaagatgctCGACTGTCTGCCGAGGaattagcaaaaaaattagaaaaattcaCTCAAACATCGGAAAATCATTTACAtacaattaatttatcaatgtCACAATTACGAGCAGTTACATATGGTGAAGATCGATATTTTCGTCGATATTGGTCTTTACCGAAATCGGGTGGTATATTTGTTGAAGCAATGGAATCCGCTGAACCTGAAGAATACGAAGAACAATTGAAAAACGATCAAAATCACACGACAGCGATTGAGGATggcagtggtggtggtggtggtggtggtattaAGAATTTGaacgaattaaataatgttgtagaaaatgttgatgatgatcattCAACTGATAAGGAAGTAAGTAATATCGTTGGGAAATCGATGGACGTTGatcatgatgatgacgataaaGAATCTCAAAATCATAATGATAATCTAAATCAATTTATCGATAATAATGAACATCGGAAAACACCAAATCGAATGATTACTGATGCcgatgctgatgatgatgacgatgaaaGCAATGTGCAATCAGTGCAAATAGAAAATGCTGCAGCTGTAAGTGGAACattaaaagaattgaaaaaaactATTGATTCAATATTACCGGAAGAACAAAAAGTGAAACAAGAACAAATGGAAATTGATGAAACAATGGATAAAAATCAATTCGAAATTAATGATGTTACTGCTAGTGCTGGTGACGCTGGCGTTATCCCATCgaataagaaatttaatttatttgaaaaattaggTCAATGTATGGAAAGAGAGAATCGTAGCGAAGATGATTTAAAAGCGGATGTCAAAGCGGAAATAAAAgaagatttaaaaaatgaaattttaaatgaattaaaaaaagttaaatgcGATTGTGTGAAATCCGACACAGAAGATAACGACGAATTGAAATGGTTCAGTATACTGAATAAGGATGGTATTACATGCAATGAAATTCATTTAACCACCGGTAATAAATGGGAAAATGGTAATGTCGGTGCATGTATTAAAGATATAACTGAATTAAAGATTCCAATATTTCCACCACCACTAATAACAAATAGTAGTAATACTGGTACTACTACAGTCAGCTGTACTACTTCTGTTGGTACTATTAGTCATGGTGGCCATAATGTCTGCGGTTCAACAAGTGCCTCATCATCATCTACGACCTCATCAACAATTATGAATCTACATCATAATTGCGAAAGTCCAGCACCACTACAAATGACGTCAGAGGAAAGTGTTCAGTTGGAATACATTAAAAAACACGGTATGCCATCGGTAACAGTGAAATCCGTACCATTTGATAAACGTCACGGATGGTGGCGCATTAAACGGCTAGATCAATTACGAGAAATTTTAGATCGTTTCCATTTACGTGGCGTTCGAGAGAAGGAATTGAAACGAAGTTTTATCATTACAATGCAACAAATGTATAACAAAGGGAAATTGGTAATTGAATATGGTGTACCGGAACTAATTAGTTTAGGTGGTAATGAACATcaccagcagcagcaacagcaagACGAAAGAACAGAAGAAGCAATGGATGTGGATAACAGTGGTGCTGGTTGTGAAGAAGACGAGAGAGAAACGGGAGCTGgtgaaacaaatgaaaaagTCGATGTGGATCGTGACTATGCGGCATCATCTGTAGCAGACGGTCAAGAAAAGAAAGATGATTTCCCATTACCAGATCAACCAGGATCGTGGAGTCAAAGTATTGCGCATCGTGTTGATATGTTCTTATTGgaacagGTTGAGGCACTAGAAGATAAAGTGGCAAATGCTAGTATGCAGGTGAAAGGCTGGAAAGTACCAGAACGTGATATTGAAGATATTCCATATGGGCATGTTGTAAATTTAGTTAAGAGTAAATTAAGTTCGCTGGAAGTGAATATTGAAAGGAGATATTTGAAACCACCACTTGGTGTCAATACTGGTACTCCACAATCTGTTTCTACAACTTCTAACCAGCAATTGTCAGTATCATCATCAACTTCTATACCTTCAACGCCATCATCAACCTCAACTTCACCATCACCGTCAATACAGCAACAACACGATGACATACCAAAAGGTTTAGCTAATTGGCGTGAAGCAGTGAATCGGGCAGCAACATCAGCTCAATTGGCAATGTGTTTGTACTCATTGGAATCGTCGATTGCGTGGGACAAAAGCATTATGAAAGCTGTGAGCGAACAAGCAGAATTTAGCATTCAGAACGCCCGCAAATATAACAGCAAGCTCACTAACTGCCAGTTTTGTCATAGTGGTGATAATGAAGATAAATTATTACTATGTGATAGTTGTGATCGTGGTTATCACACATATTGTTTTAAGCcaaaaatggaaaacattCCGGATGGTGACTGGTATTGCCATGAATGTTTAAATAAAGCAACTGGTGAACGTAATTGTATTGTATGTGGTCGAAAAATATCAACAACATCCACAAGACTATTAGTATGTGAAATATGCCCACGTGCTTATCATACTGATTGTATTCAGCCTCAATTACATAAAGTTCCTCGTGGTAAATGGTATTGTACAAATTGTATATCGAAGAAACCTCAGAAGAAAGCgaataagaaaaaagagaaGTCGAAAGATGGCAGTGGTTGTGGTGAAGCGTCCAGAGAATCAAATACAGCCACAGTAGAACAATCTCCTGTCAGTCCTGCAGCCTCTCATAGTTCAGCTGCAACAAGTGATGATGCCCCAGCATTAACATCATCATTATCTTCAACAGCAGCACCGACAGCAACTATGAACTGCAGCCAAAGTAGTGATCAATCAAATTCCAGTATTACATTAAATGCATCAGGATCTCCGTCCACCAGCATTATCATCAGTAGTCCCAGCACAATCACTGCAATCGTTAACACCCCCACCACCACAATAACTCCTTCGGCTgccacatcatcatcatcaacatcatccTCGTCATCATCTTCATCGGCGATGGCTACTACGACCACTCCAAACTATGCcccaaaaaaggaaaaatccaataaaaaattaatgaaggaATTGGCTCCGTGTCGTATTATACTGGAAGATCTGGAATGTCACGATGATGCATGGCCATTTCTATTGCCAGTGAACACTAAACAATTTCcgacatataaaaaaattataaaaattccTATGGATTTGTCAACTATTAAGAAACGATTACATGATTTGGTaTACAAATCGAAAGAAGAATTTTGTTCAGATGTTCgacaaatatttaataactGTGAAACATTTAATGAAGACGATAGTCCAGTAGGTAAAGCTGGACATTGTATGCGACAATTCTTCGAAGCCAGATGGAATGAACTTTGTTGTACTTCTCATAGTTGA
Protein Sequence
MDKENGKVNEGTSGASSKLQDQTSSILDAANLFGAYWPRSDAATNLFGSSFGLSPHAAAAALPFGILPTAAAGGTTAAVTSQSSSGRNSGGGGGSSTPSSSSAGGLSHNLSTISSSSNAQSAGSTSSASATSSSSAAVAAAAAAAAYSNAAYSNTLSVAASQAASLGMPAASAAWWSMASHLAAQEYIQRLQATTGLNFPLGAAADPYGTLALANLTALGAGGVGLGGGGASGAGSGHHKSKNSSSKNSSRSNCKDKSGTNRRNDSSDHHHHHHQQQQHHHYNQHKTNSSASSVNYNKSSSTNSLKYSSASGLTIQPTMKLPPSSNNNNRQKNNSNNSSSNSVANSSSGVVNSSISSSIFSNPLSLASTNTNSIHQSDKYLGTISIPMNNSHSSTTSTTSATNNNSGIVNSYSNSNSPQLPQSILSDPNSILGGVRLPPDTEIIKYTSSIVGPKIPGTTNRGRKKTISLDPPPSDEDMLAGIPLSDRVEVIKLPTTNGSINETSSTSEAPLNLSLKSNWSSISGNSNNNNINQNNNGSSTHLNSLSNMSVNIGTERIGTTDRISRRKPGPRPRRVVPMECTTTTTPAAPAQPPILNIPFNQFNFTTGLDSPRPPSRSEGSDGGSSTSSTSAIGGSGGGSGSGTLNHSNKEGRPRNLGRGVSKPKKNTVASLLAQSRALGIKPVPMLDPSNTSTMNQQMQLLRSNIMDAQRYISEVGGDEKALNKFLQEKFKGPLSDGSTVDASDSDNFTDSNHTDSELETEQVPLMKRPKHYDERLLRVPLEKGWRRETLIRGVTKTGGIKGDVTYSAPESTNKFKQMSDVTQYLEYQKNLELSKENFTFSCRAIIGDYLQPIPPEMQTDGTEYIFLTEEDVTKRLDELKAAMRTSIPVEQRIEMAKKQQAARAAARLDREQQRLNKELERNERQEAARREKEARTQQMLEAKRKRQEELEKQKQEEQQRKQQERELKRQQAAMLKEQIYIQEVNKQREMLYTVELEKERRRQHLALIKAMENRRKLEEKERRKQQLLAEKQANREKKLEQRKVDLEILAELRKPCEDLELNQNDLPEYERIPGVKLCGKAFADTLMVFEFLHNFGEVLGFDMESLPTLESLQQALMPNEHTYEAEEELFSVMTHLLVCAIEDPGIPNPARHTTILGQSLRQADITHTNLSEILRIYLYANATGEVKALTGVHFERDREKRVADHHQTDDEMQQTLNGKNAHYYELLHENPTYKMSDLLRDKPFIALTPTDKAAILAFICNELLQNKTVLRQIENSLENMIQHKRDKWLLDQKIRKLRVVHNRKIRNEAALEKCHMIKCNNDSGVDDAVSAAGGSGHGGGGASLDSPHTSHKDDLLDDDVVDHEMSDNESVGTQPEEEEDARLSAEELAKKLEKFTQTSENHLHTINLSMSQLRAVTYGEDRYFRRYWSLPKSGGIFVEAMESAEPEEYEEQLKNDQNHTTAIEDGSGGGGGGGIKNLNELNNVVENVDDDHSTDKEVSNIVGKSMDVDHDDDDKESQNHNDNLNQFIDNNEHRKTPNRMITDADADDDDDESNVQSVQIENAAAVSGTLKELKKTIDSILPEEQKVKQEQMEIDETMDKNQFEINDVTASAGDAGVIPSNKKFNLFEKLGQCMERENRSEDDLKADVKAEIKEDLKNEILNELKKVKCDCVKSDTEDNDELKWFSILNKDGITCNEIHLTTGNKWENGNVGACIKDITELKIPIFPPPLITNSSNTGTTTVSCTTSVGTISHGGHNVCGSTSASSSSTTSSTIMNLHHNCESPAPLQMTSEESVQLEYIKKHGMPSVTVKSVPFDKRHGWWRIKRLDQLREILDRFHLRGVREKELKRSFIITMQQMYNKGKLVIEYGVPELISLGGNEHHQQQQQQDERTEEAMDVDNSGAGCEEDERETGAGETNEKVDVDRDYAASSVADGQEKKDDFPLPDQPGSWSQSIAHRVDMFLLEQVEALEDKVANASMQVKGWKVPERDIEDIPYGHVVNLVKSKLSSLEVNIERRYLKPPLGVNTGTPQSVSTTSNQQLSVSSSTSIPSTPSSTSTSPSPSIQQQHDDIPKGLANWREAVNRAATSAQLAMCLYSLESSIAWDKSIMKAVSEQAEFSIQNARKYNSKLTNCQFCHSGDNEDKLLLCDSCDRGYHTYCFKPKMENIPDGDWYCHECLNKATGERNCIVCGRKISTTSTRLLVCEICPRAYHTDCIQPQLHKVPRGKWYCTNCISKKPQKKANKKKEKSKDGSGCGEASRESNTATVEQSPVSPAASHSSAATSDDAPALTSSLSSTAAPTATMNCSQSSDQSNSSITLNASGSPSTSIIISSPSTITAIVNTPTTTITPSAATSSSSTSSSSSSSSAMATTTTPNYAPKKEKSNKKLMKELAPCRIILEDLECHDDAWPFLLPVNTKQFPTYKKIIKIPMDLSTIKKRLHDLVYKSKEEFCSDVRQIFNNCETFNEDDSPVGKAGHCMRQFFEARWNELCCTSHS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-