Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 4e-05 0.76 11.0 0.0 21 44 67 90 61 96 0.91

2 5 6.5e-05 1.2 10.3 0.0 24 48 98 122 91 126 0.85

3 5 0.0013 24 6.2 0.1 21 52 123 154 119 156 0.86

4 5 0.092 1.7e+03 0.2 0.1 26 47 188 209 173 214 0.87

5 5 0.013 2.4e+02 3.0 0.0 27 45 220 238 216 242 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	4e-05	0.76	11.0	0.0	21	44	67	90	61	96	0.91
2	5	6.5e-05	1.2	10.3	0.0	24	48	98	122	91	126	0.85
3	5	0.0013	24	6.2	0.1	21	52	123	154	119	156	0.86
4	5	0.092	1.7e+03	0.2	0.1	26	47	188	209	173	214	0.87
5	5	0.013	2.4e+02	3.0	0.0	27	45	220	238	216	242	0.89

Coding Sequence: ATGAAAGACCCAAAATACCACCAAATATCAAACAAACCATCACGACAATACTCTCAATTACCAAAGCGCAAAAGCAGTCGTAGAAAACCGCAAAACCGACCTGCGCCCGCTTACGTTGAAAAGTATTTCCAATGCGATTACTGCGACAAAAGTTTCGCACATTTAtccaatctgaaaattcacgtgCGGATACACACCGGAGAAAAGCCGTACAAGTGCGACATTTGCCAAAAAACCTTCCGTCAAAAGGGAAACATGAAGTATCACTTACTATCCCACGCCAATGTAACGCCGTACGAATGCGAAGTTTGCGGGAAAACTTTCCGGCAATCCcgcgatttcaaaaatcatatgCGGATTCACACAGGGGAAAAACCGTATACTTGCGATCTTTGCAACATGGATTTTCGAACGTTGAGTAGTTTGAGATATCACTCGAAGAAACACGAGATTAAGAAACCGAAATTCCGCTCGCCTGTTCGCAACAATCATAAATTTCGCTCGCCTGTTCGCAacaatcagaaattttgctCGCCTGTTCGTTATGAGGGAAGACAGTACGAGTGCGATGTTTGCGAGAACAGTTTTACGCGGGCATGTTCTTTGAAACATCACCTCCAGTTGCACATGAAGAATGGTGGGAAAAGACTGTATGAATGCGATGTTTGCAAATCGACTTTTTCGATGTtcaggaatttgaagaaacaTGTCGGCGTGCATAATAAGGAGAATGGGTTGAATTGCGATGTTTGCGGAGAGAATTTTACGACACTGAAAGAAATTGAGCCGCATACGCATTATGTGAAAATGGATGATATCGTTATGGAAGAAAAATTGGGAGGTTTTATGATTGAAAagggAGATCTCCACTCGGCAAGGGATACAATTGAGAACATCAAAGTGGAAGAGGTCGAAATCGAGTGCGAAGATGGCCAACTGGTAATTTGTATGAAGATAACACACTTCTGCATATGA
Protein Sequence: MKDPKYHQISNKPSRQYSQLPKRKSSRRKPQNRPAPAYVEKYFQCDYCDKSFAHLSNLKIHVRIHTGEKPYKCDICQKTFRQKGNMKYHLLSHANVTPYECEVCGKTFRQSRDFKNHMRIHTGEKPYTCDLCNMDFRTLSSLRYHSKKHEIKKPKFRSPVRNNHKFRSPVRNNQKFCSPVRYEGRQYECDVCENSFTRACSLKHHLQLHMKNGGKRLYECDVCKSTFSMFRNLKKHVGVHNKENGLNCDVCGENFTTLKEIEPHTHYVKMDDIVMEEKLGGFMIEKGDLHSARDTIENIKVEEVEIECEDGQLVICMKITHFCI

Sequence clustering based on sequence similarity using MMseqs2