Pign102337.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Platerodrilus igneus
Gene Symbol
NEDP1
Assembly
GCA_036346225.1
Location
JARFIW010001103.1:3807929-3810723[+]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 6.7e-10 3.9e-06 29.8 0.4 20 73 7 57 3 59 0.90

Sequence Information

Coding Sequence
ATGGAAAAGAGAGGAAGTTGTCCGAAAAACGGTGCTAATAAAGGCAAAATTGACATCTACATAACATCTCCAAAAGGGAAAATTTTCAGATCACAGAAAGAGCTAAAAATTTATCTTCAAGAAAAAAAGTTTCCATACAAAATTGAAGATTTTAGATTTTCTACAAAAAACGATATTATAAGCCCAATTGTAACTGACCCAGCAGTATATAACTATACAATTACTGCTATTTCAGATATGAACAAATTAGAAGAGGATATATCCAATCatacaaataaatcccaaactTTACATAGAACCATTCATACACAAACTGAAAACGATTATGATAGGATGATGATCACAAATGAACTTTTGGGCAGGAATTGGCTATCTGATATGACTATACAAAAGTATTTTGATCTATTAAATAATCATTTTCTTTCATCAAGATCGTGCTTGATCATAAATCCCCTAATATGTCATGCAGTAAAATGCATAGATGACTTTTTTCATTTTCTCGACCCATTAGAAATTaaaacaaagaacatcttattaatgCCGGTGAATGATTCACGATCACTTGATTCTCCAAGTGGTTCTCACTGGAGCCTTTTGGTATATAGCAAACTAGCTAACACCTTCTACTATTATGATTGTTTGAAGGGAAATCAGAATCTTACATCTGCAGAATCAGTGGCCAATAAAATGTCACTATACTTAACTGGTATCACCAAACCTAAATTTCGTCTTATAGAAGCCAACATCAATGAACTATCGAAAGAGCTTCTTTACTCCTTAGTTTTTGAAACCACCACAGAAACAAGAAGCTCTTTAAAAACCTCTAACAGCATTCATAATGATGAACACTTCTTGATACAAACTGATTCAAATTCAAATGGAAGCCTAAAGACAGATGATAGTTTGAATATTAAgagaaatgaattaattaataaccCAAGAGCTACGGTACAAGGGCATCAACAACAACATAAGTCATCAACGGCAGTAGCAAATGACTGTACCGGAGAAATGAACATCATCAACAACAAAGAGAATAACAAAGATTCTAACAATGTAAAAAACAAAACCAGAATATTACTCCTGGCTGATAACCATGGACGAGGTTGTTTTGATAAACTACAATCCCTATCTAATAACAATACTCAGATTCAGTGTATTTTTAAACCAGGCGCTACCTATGAAAAGATTATTGAACACATTGGACCTAAAATAAAAGACTTCACCAATAATGATTATGTAGCAACAATAGGAGGTTCTAATAATACTATACAAGGAAAATCACTTGATAAAGTACTATTTTCTGAAATGCTTAAGGCATTAAAAGATACAAATGCCATATTTATTACTGCGCCATACTGGTATGGTCGCCCATACTTAAACCAATATTTATATCGTTTTAACTCGGAACTAATGAATGGACTACGCAATACTAAACATAAATTCATTGATATAAATACAATAGTGTTTCCAAGAAATTTTACTCATTATGGGTTTTATCTGAATAAAACTGGCAAATATAAACTATGCAAAGCCATTGCTGATGCAGCAAAAGCAGGCGAAAAAATGTATCAAGGTACTGGTAGCagcaatttaattgaaattaaatgcaCTCCTGGGAACATGAATATTAATCCATTGAATTCACATGTAGATAAGAACAATCTCATTGAAAGTAGGAACTCCATAGAAACACAAGCTATTCCAAATCGTCCCAGATCCAAGGTGATAAGCTCTAATCCAAAAGTCAACGAACAAACTCAGATTGGGACTCTAAGGGTGCTATTAATTAATATTCAGTCCATTAGGTGTAAAACGGATAACTTACATATTTTATGTAAAACTTTATGTTTCCCGGACATATTACTAATAACTGAGCATTGGCTTATTCCAGACGAAGTAGTATATATAAAGAACTGCTCAATAATATCTACATTTCAACATTCACGCTTAACGCATGGATCACTTATAATGTGTAAGAATAAAACTCTTTATCAAGCCATTCATACATTTGACTTCCTGCTTGCCGAACAACAATTTGAATTTACTGTTGCATTCAGAGAAGATGCACATCTTTTTATTATTTGCATATATCGATCACCAGGACAGCTGCAATCTAACATAAACGTCTTCTTAAAAAATCTAGAACTATTACTTGATAATCTTCCAAAGAAGAGTAAAATACTCCTAGCCGGAGATTTTAATATAGATTACTCTAGAGTCTCTGCAACAAAAACTCGTTTAGAAAATTTACTACTATCTTTTGATTTGCAAATGCATGTAAAAGATTTCACTCGGTACAAAAATGGCGGTAGATCTATTATTGATTATATATGTACCAATCTTGGCAATGATACAGTTACTTCACGGGTTATTGATGGGCTAGCTGATCACCAGGCGGTAGTGGCTAACTTGCTTCTGTCAGTAAGGAAAAATCATAGTAAATCTAGAACAAAAGTTGGCAgattattttcaaagcaaaacttTAAGAGATTTAATGAAGCATGCTGCAAAGCCGACTGGAAAAGATGTTTGTTACAAGAAACATTTAATgataaatttaactttttttag
Protein Sequence
MEKRGSCPKNGANKGKIDIYITSPKGKIFRSQKELKIYLQEKKFPYKIEDFRFSTKNDIISPIVTDPAVYNYTITAISDMNKLEEDISNHTNKSQTLHRTIHTQTENDYDRMMITNELLGRNWLSDMTIQKYFDLLNNHFLSSRSCLIINPLICHAVKCIDDFFHFLDPLEIKTKNILLMPVNDSRSLDSPSGSHWSLLVYSKLANTFYYYDCLKGNQNLTSAESVANKMSLYLTGITKPKFRLIEANINELSKELLYSLVFETTTETRSSLKTSNSIHNDEHFLIQTDSNSNGSLKTDDSLNIKRNELINNPRATVQGHQQQHKSSTAVANDCTGEMNIINNKENNKDSNNVKNKTRILLLADNHGRGCFDKLQSLSNNNTQIQCIFKPGATYEKIIEHIGPKIKDFTNNDYVATIGGSNNTIQGKSLDKVLFSEMLKALKDTNAIFITAPYWYGRPYLNQYLYRFNSELMNGLRNTKHKFIDINTIVFPRNFTHYGFYLNKTGKYKLCKAIADAAKAGEKMYQGTGSSNLIEIKCTPGNMNINPLNSHVDKNNLIESRNSIETQAIPNRPRSKVISSNPKVNEQTQIGTLRVLLINIQSIRCKTDNLHILCKTLCFPDILLITEHWLIPDEVVYIKNCSIISTFQHSRLTHGSLIMCKNKTLYQAIHTFDFLLAEQQFEFTVAFREDAHLFIICIYRSPGQLQSNINVFLKNLELLLDNLPKKSKILLAGDFNIDYSRVSATKTRLENLLLSFDLQMHVKDFTRYKNGGRSIIDYICTNLGNDTVTSRVIDGLADHQAVVANLLLSVRKNHSKSRTKVGRLFSKQNFKRFNEACCKADWKRCLLQETFNDKFNFF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-