Basic Information

Insect: Plagodis pulveraria
Gene Symbol: topi
Assembly: GCA_963890685.1
Location: OY982957.1:10902441-10917812[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 23 0.0079 1.3 11.2 0.5 3 23 210 231 209 231 0.90

2 23 2 3.3e+02 3.7 1.5 3 23 575 597 574 597 0.84

3 23 0.053 8.8 8.6 0.6 1 21 602 622 602 623 0.96

4 23 5 8.4e+02 2.4 0.2 1 23 664 687 664 687 0.89

5 23 0.0028 0.46 12.7 1.0 3 22 698 717 698 717 0.96

6 23 0.092 15 7.9 0.7 3 23 768 789 766 789 0.94

7 23 0.013 2.2 10.5 0.3 1 23 795 818 795 818 0.95

8 23 0.1 17 7.7 0.0 1 23 844 867 844 867 0.90

9 23 0.0044 0.74 12.0 3.5 1 23 872 894 872 894 0.97

10 23 0.0068 1.1 11.4 0.1 1 23 900 923 900 923 0.95

11 23 0.0014 0.23 13.6 1.5 1 23 936 958 936 958 0.97

12 23 0.00014 0.024 16.7 1.8 1 23 1007 1030 1007 1030 0.97

13 23 0.0039 0.64 12.2 1.7 1 23 1092 1115 1092 1115 0.96

14 23 0.0016 0.27 13.4 1.5 2 23 1140 1162 1139 1162 0.95

15 23 0.2 34 6.8 0.1 2 23 1168 1190 1167 1190 0.93

16 23 0.008 1.3 11.2 0.2 1 21 1235 1255 1235 1256 0.95

17 23 0.00099 0.17 14.1 0.6 1 23 1266 1288 1266 1288 0.93

18 23 9.1e-05 0.015 17.3 0.3 2 23 1377 1399 1377 1399 0.93

19 23 6.2e-07 0.0001 24.1 1.3 3 23 1406 1426 1405 1426 0.98

20 23 9.2e-05 0.015 17.3 0.2 1 23 1444 1466 1444 1467 0.96

21 23 0.17 28 7.0 0.0 1 23 1488 1510 1488 1510 0.98

22 23 0.022 3.7 9.8 0.6 1 23 1516 1539 1516 1539 0.95

23 23 0.00021 0.034 16.2 0.4 1 23 1547 1570 1547 1570 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	23	0.0079	1.3	11.2	0.5	3	23	210	231	209	231	0.90
2	23	2	3.3e+02	3.7	1.5	3	23	575	597	574	597	0.84
3	23	0.053	8.8	8.6	0.6	1	21	602	622	602	623	0.96
4	23	5	8.4e+02	2.4	0.2	1	23	664	687	664	687	0.89
5	23	0.0028	0.46	12.7	1.0	3	22	698	717	698	717	0.96
6	23	0.092	15	7.9	0.7	3	23	768	789	766	789	0.94
7	23	0.013	2.2	10.5	0.3	1	23	795	818	795	818	0.95
8	23	0.1	17	7.7	0.0	1	23	844	867	844	867	0.90
9	23	0.0044	0.74	12.0	3.5	1	23	872	894	872	894	0.97
10	23	0.0068	1.1	11.4	0.1	1	23	900	923	900	923	0.95
11	23	0.0014	0.23	13.6	1.5	1	23	936	958	936	958	0.97
12	23	0.00014	0.024	16.7	1.8	1	23	1007	1030	1007	1030	0.97
13	23	0.0039	0.64	12.2	1.7	1	23	1092	1115	1092	1115	0.96
14	23	0.0016	0.27	13.4	1.5	2	23	1140	1162	1139	1162	0.95
15	23	0.2	34	6.8	0.1	2	23	1168	1190	1167	1190	0.93
16	23	0.008	1.3	11.2	0.2	1	21	1235	1255	1235	1256	0.95
17	23	0.00099	0.17	14.1	0.6	1	23	1266	1288	1266	1288	0.93
18	23	9.1e-05	0.015	17.3	0.3	2	23	1377	1399	1377	1399	0.93
19	23	6.2e-07	0.0001	24.1	1.3	3	23	1406	1426	1405	1426	0.98
20	23	9.2e-05	0.015	17.3	0.2	1	23	1444	1466	1444	1467	0.96
21	23	0.17	28	7.0	0.0	1	23	1488	1510	1488	1510	0.98
22	23	0.022	3.7	9.8	0.6	1	23	1516	1539	1516	1539	0.95
23	23	0.00021	0.034	16.2	0.4	1	23	1547	1570	1547	1570	0.96

Sequence Information

Coding Sequence: ATGAGTGTGAACTATGATCGTGTTTGTAGACTGTGCTTGTCATCTCGAGGCGAATTACTGCCGATTTTCCCTACCACCAGTTCGGATGACTCTGAGTCCCCCGTCCTCGTCTCAAAAATCAAGGATTGCGTATCGGTGCAGATAAACGAAAATGATGAACTGCCGACGAATGTCTGCAGGAAATGCATGGACAATGTCAATAACTGGCATATATTCAAGACTGTATGTGAAAAGACTCAAAACAAACTACAGTCTCTGATTAAAAAGGATGGCAGCCTACTAGAAGAGGTAAAAATAAAGAGTGAACCATTGTCTGATGAAGCATATGATGATGGAGTGGTTATTGATGGCTCGTACCCAGTCATTGAGAATACCACCTCAGCAAGCAAGCTGCAGCCAGAAGGACCTCCTATCCTGGCTTCATTGGGACTCACACCACGGAGTGATAAGGGGGTGGAGAGCGAGAATAATGAAGACGAGGACTACGAGGAAGAAATGAACGAGCAGCATCAGGCTCCTGAACCGATGAAAGTTCCAAATATGCCTGAGGTCTCCATCACCGTAATGAGGCCGACTGGTGAGACCCTACACTCCCGTCAAGGCATTCAGCAGCTTGCCTCCAAGGACTGTCTTATCTGCGGACGCTCTTACAGATACTCCCACAATGCCCGCAGGCATGAACTAGCAGCACACAGCTTCGACCGCTACACCAACAAAGTTACAAACAAGAAATCTAATCACTCAATTATGCAACCTAAACTCAGGCCCAACCCGTTCAATCCCAAAGCTAGGCTTATGCCCAATCCTATCAGCCATAAACTACAACTCATGCCCAAAAATCCCGCCAAAATGCTACAGAAATCTACCCCACCGAAACCAATACCCATTAAAACTTCTAAAACGCAACAAAATAACTTACCATACCCTTTACGCATTAAGGCGCTCAAAGACttacaaataaagaaaaaagaaccaCAGATTTTGAAGACTTTGCTCACTGCTAAGCCGGAAGTATTAGTTTCGGAACCGGAGATAATGAACTCGGGACCAGAAAGTCCGGAAACCTTAATATCCGAACCGGAAATCGCGTCATTCCAGGTAGAAGCCATTCTATCGGAGCCTACTGATTATGATCAAAATCAAGAAGATGGTGAAATGGAACaccatagtcaaaatcaaaattacgATACTGTGGACATGGAATCAGATCACGAGATTGAAATCGCCCGTCAACAGGAAAACGAAGGAGACAATTTGGAAAATATCGAAAATGAAAATGAGCACCTTGAAGAAAACCATATCGATAACGATGAAAAGCAGGTCGAGAGTGACAATGATGTTGAGCTGGATAACGGCGACAGTCAGGGACTGATGGAGATTGATGATGCTCAAGAAGTTCACGTCGGTGAAGATGAAGGCAAGGAAGAGGAAACTAATCTAGAAGGCGAAAATGACGAACAAGAGATCAATCCTGAAGCTGATGACCATGACGAAGCGGAATCAATTCTGCCAACTCCCATAGTTGAATTGAACGAAATGCAAAACAATTCGTGTAGCGAGCTAAATGACGAAGACGAAGAATTAGACGAAACTGCCGATATCAGCGAAACCATAGAACAAGATCCAAAAGTCCTCGATCCTGACAAAACATACGTCACCAAAGCCCAAAGAGATTTTATCGTCAAGTTTCGCAATGTCATACAACAAATCAACACCAAACGTTGTCTCTGCTGCGATAAGACATACCCACGCAGGAAGGCCGTTGTTCAGCATTTACAGAAAAATGGACACAAGGTGCCCAAGCATACCTGCTACAACTGCGTGGTTACGTTTACTCATATCGGCGCTCTCCTTAGCCATATGAGACAGAACGCTTGTACGGATCTTTGGAAAATTATCTATGACGAAAATGGTATTTCTGATGACATGGTTTTGGAAGATGAGCCTAAAAACAAGGTTCAACCTAAAGATATTTTCAACGCCCGATCTTACGCGTGCCGACTTTGTCCGGCTAAGTTCCAGTTAAAGCAGTCCATAATGAAACACGTATTGGATGTGCATGAAGACGGCCAGTCTGCAGTGCCACTCGGCTGCGTTCACTGCCGTGCGAGCTTCAAAGACAGAACATTGCTCAAGAAACACATTCGCGTCGGTGAATGCACAGTTTACATACATTGCGATTTGTGTTCTGATCAATTTTCTAACATGCAGGACTTCAGCGAACACGCCTTATCAGCACACGCTGACCACTTCGAGACAGCAGGCAACCAAAACAAATGTATCGATGGCCGGGCAACAGACTGCTCTATTTGCGGCAAGAAAAACAGTAACTACTTGAATCTAGTGAAACATTTGAAATTTGTTCACAATGAAGATAGACCTCATTACTGTCAAAATTGTGACGCTAAGTTCGAACTAGCTGCTGACCTTAACAATCATATTTATGTGGAGCATTCAAATCAAGCGTTAGGTTTGCAGCCTCAGGAGCCCGATATGTCCCTTGTGAAAGAAGAAGCCGAGGAGTATCACTACTCGTGCACAGAATGTAACGCCATATTCGAAACTGTCGACGCATGGACGGACCATCAAGTTGCGGAACACAACCAAGTCGCCCATCATTGCGACCAGTGCGACAAAAAGTTCTTGCGACCTTCTGAACTCGCTGAACACAAAAATACCCACTTGAGAGTTAAGTTCTATCCTTGCAGTGTATGCCCGAATTCATACAGCACCCCTCAAAAGCTGTCTGACCATGTGCAGCAAGTCCACCCCGGAGCGGGCAATAATGCCAACGCAGAGACAGAATTTTTCTGCGATATATGCATCCGTTCATTCAAAAGTCGTCAGGCGTTTTCAAATCACATGCGTATACACGCTAAAGTGCCGACTACGAACAGAAAACCAGGTGAACCTAAAGGATTCGATCCGCGCATTATCGGAAAACCAATCAAACAATTTACCATAGTTCAACCTGGCTTTCTCAACTTCAAGCCAAATGCTAACGTTCCTAATGCGCCTTACTCATGTGATATTTGTGGTAAAGGCTTCATGCATAAGAAGAATATATGGAAACATAAGAAAGTCCTGCATGCGGATATCGTAAATGATAGGAACGACAGCGAAGATAACACTATGCATGCCTCTACAGAAGATGACGATTACAATCCTGATGAAAATGGAGCACTCTCCACGCCGCAATTCGACAGCTTCAACTTCTCTAACTTCTCCAGCAACAGCACACCACAAAAGTCTCAGGTTCAGGCGGATATGCCATATTCATGCGAATTGTGCTTCAAGCGATTCCCGCTTAGAACTAGTTTGTGGAAGCATAAACGCGCTAAACATGGTATCGTGAACCCTGGTGGCGGCGGCGGCAACAATGATACACAAACGACGCCAGGAGAGAGTGGCAGATCTAGTTGCACAATTTGTAAAATCACATTTGCGGACAAGAAATCATATTATCGTCATAGGAAGAATGTTCACAAAACTGCTACACAGATGTGTAAGCTTTGCGGGAAGCCGCTCAATTCTACTTTGGAGCTCTATGAACATCTCAAAGCTGCACACGCTCGAGAATTGCTGGGCTATAATGCCAACCAAGGCTCGAACAAAACTCAACCAGACACTTCTCAAGATCTTGATGTTGACTATGATAACGAGCCGGAGCCGGCAGATCCTGGCCTGGACTATCAAGCCCGGTACCCGTGCGATACATGCGGCAAGCAGTTTGTGGGTCTGCTGGCGTTACAGAACCATCAGTGTATAAATCAGATTACTTCGCAACCGCAGACTTTCGACTGCGAAATTTGCCACAAAAGTTACACATCAATTGCTGCCTTGAAAAGTCATCGTGGTTGGCACTTGCGCTCTCCCGACGGTAAAGCCGCTGCCAACAACAGCGGTCTTTGGATGCCTCAGCACAAAGTGACGAGTAAAGTCAGCAAGCACGAGATCGTTGACGCGGTTCAGTTGGCTCGGGTCTCGCATTCGTCTCCCGCCGCTGCCGTCACTGCCAAAAGGAGATTACCGCCGGAGGTCGAAGTGACTGTCGTCAATCCGAATAAAAAGATGCGCTCCGATGACTCCGTCGAAATGGATCAAAGCAACGACGCGTTAGAAGGGAGGTACTGCACAATTTGCGACAAAGAGTTTACTAAACGCGCCGCTTATCAGCGTCACATGGATGAGGTGCATCAGCCAAACTCTGTGTTTTGTCCGGTATGTGACAGGAGTTTCACGAGGAAATCGACACTTCTCGTGCATATGAAGAAGCATTACGAAAGTGGGGAGGGTACGTCCGCCACTGGGCATGTGGAAGACGAGGGTTACCCGTGTGAAGTGTGCGGTGCGGTCTTTGATACGGAGAAGTCTTTGAGGGGTCATATGGCGAGGCATCACGCTGATGATTCGGGGGAATCTGAGGACGAAGGCAATGCGCCTGCTGCTCCGCCAGGCGAATTCACTTGTGGACAGTGTGGAGATGGCGTGGCCAGTCCTCGAGATTTGCTCGCCCACCGTTCGATGCACGCAACTCCCACCAAATTCTTCTGCAACATCTGCAAAGTATACTTCGCTCGAGCGTTAGACCTCTCGTCGCACACGCGCGCACGCCATTCCGACAAcgaaaaagttttcttcccctGTGCCATGTGTGACCGCTTCTATATGAACAAGAAGAGTTTACAAAGACATATTGAAATGGCACATTGA
Protein Sequence: MSVNYDRVCRLCLSSRGELLPIFPTTSSDDSESPVLVSKIKDCVSVQINENDELPTNVCRKCMDNVNNWHIFKTVCEKTQNKLQSLIKKDGSLLEEVKIKSEPLSDEAYDDGVVIDGSYPVIENTTSASKLQPEGPPILASLGLTPRSDKGVESENNEDEDYEEEMNEQHQAPEPMKVPNMPEVSITVMRPTGETLHSRQGIQQLASKDCLICGRSYRYSHNARRHELAAHSFDRYTNKVTNKKSNHSIMQPKLRPNPFNPKARLMPNPISHKLQLMPKNPAKMLQKSTPPKPIPIKTSKTQQNNLPYPLRIKALKDLQIKKKEPQILKTLLTAKPEVLVSEPEIMNSGPESPETLISEPEIASFQVEAILSEPTDYDQNQEDGEMEHHSQNQNYDTVDMESDHEIEIARQQENEGDNLENIENENEHLEENHIDNDEKQVESDNDVELDNGDSQGLMEIDDAQEVHVGEDEGKEEETNLEGENDEQEINPEADDHDEAESILPTPIVELNEMQNNSCSELNDEDEELDETADISETIEQDPKVLDPDKTYVTKAQRDFIVKFRNVIQQINTKRCLCCDKTYPRRKAVVQHLQKNGHKVPKHTCYNCVVTFTHIGALLSHMRQNACTDLWKIIYDENGISDDMVLEDEPKNKVQPKDIFNARSYACRLCPAKFQLKQSIMKHVLDVHEDGQSAVPLGCVHCRASFKDRTLLKKHIRVGECTVYIHCDLCSDQFSNMQDFSEHALSAHADHFETAGNQNKCIDGRATDCSICGKKNSNYLNLVKHLKFVHNEDRPHYCQNCDAKFELAADLNNHIYVEHSNQALGLQPQEPDMSLVKEEAEEYHYSCTECNAIFETVDAWTDHQVAEHNQVAHHCDQCDKKFLRPSELAEHKNTHLRVKFYPCSVCPNSYSTPQKLSDHVQQVHPGAGNNANAETEFFCDICIRSFKSRQAFSNHMRIHAKVPTTNRKPGEPKGFDPRIIGKPIKQFTIVQPGFLNFKPNANVPNAPYSCDICGKGFMHKKNIWKHKKVLHADIVNDRNDSEDNTMHASTEDDDYNPDENGALSTPQFDSFNFSNFSSNSTPQKSQVQADMPYSCELCFKRFPLRTSLWKHKRAKHGIVNPGGGGGNNDTQTTPGESGRSSCTICKITFADKKSYYRHRKNVHKTATQMCKLCGKPLNSTLELYEHLKAAHARELLGYNANQGSNKTQPDTSQDLDVDYDNEPEPADPGLDYQARYPCDTCGKQFVGLLALQNHQCINQITSQPQTFDCEICHKSYTSIAALKSHRGWHLRSPDGKAAANNSGLWMPQHKVTSKVSKHEIVDAVQLARVSHSSPAAAVTAKRRLPPEVEVTVVNPNKKMRSDDSVEMDQSNDALEGRYCTICDKEFTKRAAYQRHMDEVHQPNSVFCPVCDRSFTRKSTLLVHMKKHYESGEGTSATGHVEDEGYPCEVCGAVFDTEKSLRGHMARHHADDSGESEDEGNAPAAPPGEFTCGQCGDGVASPRDLLAHRSMHATPTKFFCNICKVYFARALDLSSHTRARHSDNEKVFFPCAMCDRFYMNKKSLQRHIEMAH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01208517;
90% Identity: iTF_01208517;
80% Identity: -