Basic Information

Insect: Plagodis dolabraria
Gene Symbol: topi
Assembly: GCA_963854805.1
Location: OY978448.1:10366787-10381514[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 23 0.0085 1.4 11.2 0.5 3 23 208 229 207 229 0.90

2 23 2.1 3.5e+02 3.7 1.5 3 23 572 594 571 594 0.84

3 23 0.035 5.8 9.3 0.6 1 21 599 619 599 620 0.96

4 23 5.5 9.1e+02 2.4 0.2 1 23 661 684 661 684 0.89

5 23 0.003 0.5 12.7 1.0 3 22 695 714 695 714 0.96

6 23 0.099 16 7.9 0.7 3 23 765 786 763 786 0.94

7 23 0.014 2.3 10.5 0.3 1 23 792 815 792 815 0.95

8 23 0.11 18 7.7 0.0 1 23 841 864 841 864 0.90

9 23 0.0048 0.8 12.0 3.5 1 23 869 891 869 891 0.97

10 23 0.0074 1.2 11.4 0.1 1 23 897 920 897 920 0.95

11 23 0.0015 0.25 13.6 1.5 1 23 933 955 933 955 0.97

12 23 0.00016 0.026 16.7 1.8 1 23 1004 1027 1004 1027 0.97

13 23 0.0042 0.69 12.2 1.7 1 23 1089 1112 1089 1112 0.96

14 23 0.0018 0.29 13.4 1.5 2 23 1135 1157 1134 1157 0.95

15 23 0.076 13 8.2 0.1 2 23 1163 1185 1162 1185 0.93

16 23 0.0087 1.4 11.2 0.2 1 21 1230 1250 1230 1251 0.95

17 23 0.0011 0.18 14.1 0.6 1 23 1261 1283 1261 1283 0.93

18 23 9.8e-05 0.016 17.3 0.3 2 23 1372 1394 1372 1394 0.93

19 23 6.7e-07 0.00011 24.2 1.3 3 23 1401 1421 1400 1421 0.98

20 23 0.0001 0.017 17.3 0.2 1 23 1439 1461 1439 1462 0.96

21 23 0.18 30 7.0 0.0 1 23 1483 1505 1483 1505 0.98

22 23 0.024 4 9.8 0.6 1 23 1511 1534 1511 1534 0.95

23 23 0.00022 0.037 16.2 0.4 1 23 1542 1565 1542 1565 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	23	0.0085	1.4	11.2	0.5	3	23	208	229	207	229	0.90
2	23	2.1	3.5e+02	3.7	1.5	3	23	572	594	571	594	0.84
3	23	0.035	5.8	9.3	0.6	1	21	599	619	599	620	0.96
4	23	5.5	9.1e+02	2.4	0.2	1	23	661	684	661	684	0.89
5	23	0.003	0.5	12.7	1.0	3	22	695	714	695	714	0.96
6	23	0.099	16	7.9	0.7	3	23	765	786	763	786	0.94
7	23	0.014	2.3	10.5	0.3	1	23	792	815	792	815	0.95
8	23	0.11	18	7.7	0.0	1	23	841	864	841	864	0.90
9	23	0.0048	0.8	12.0	3.5	1	23	869	891	869	891	0.97
10	23	0.0074	1.2	11.4	0.1	1	23	897	920	897	920	0.95
11	23	0.0015	0.25	13.6	1.5	1	23	933	955	933	955	0.97
12	23	0.00016	0.026	16.7	1.8	1	23	1004	1027	1004	1027	0.97
13	23	0.0042	0.69	12.2	1.7	1	23	1089	1112	1089	1112	0.96
14	23	0.0018	0.29	13.4	1.5	2	23	1135	1157	1134	1157	0.95
15	23	0.076	13	8.2	0.1	2	23	1163	1185	1162	1185	0.93
16	23	0.0087	1.4	11.2	0.2	1	21	1230	1250	1230	1251	0.95
17	23	0.0011	0.18	14.1	0.6	1	23	1261	1283	1261	1283	0.93
18	23	9.8e-05	0.016	17.3	0.3	2	23	1372	1394	1372	1394	0.93
19	23	6.7e-07	0.00011	24.2	1.3	3	23	1401	1421	1400	1421	0.98
20	23	0.0001	0.017	17.3	0.2	1	23	1439	1461	1439	1462	0.96
21	23	0.18	30	7.0	0.0	1	23	1483	1505	1483	1505	0.98
22	23	0.024	4	9.8	0.6	1	23	1511	1534	1511	1534	0.95
23	23	0.00022	0.037	16.2	0.4	1	23	1542	1565	1542	1565	0.96

Sequence Information

Coding Sequence: ATGAGTGTGAACTATGATCGTGTTTGTAGACTGTGCTTGTCATCTCGAGGCGAATTACTGCCGATTTTCCCTACCACCAGTTCGGATGACTCTGAGTCCCCCGTCCTCGTTTCAAAAATCAAGGATTGCGTGTCGGTGCAGATAAACCAAAATGACGAACTGCCGACGAATGTCTGCAGAAAATGCATGGATAATGTCAATAACTGGCATATATTCAAGACTGTATGTGAAAAGACACAAAACAAACTACAGTCTCTGATTAAAAAGGATGGCAGCCTACTAGAAGAGGTAAAAATAAAGAGTGAACCATTGTCTGATGAAGCATATGATGATGGAGTGCTTATTGATGGCTCGTACCCAGTCATTGAGaatACCACCTCAGCAAGCAAGCTGCAGCCAGAAGGACCTCCTATCCTGGCTTCATTGGGACTCACACCACGGAGTGATAAGGGGGTGGAGAGCGAGAATAATGAAGACGAGTACTACGAGGAAGAAATGAAGCATCAGGTTCCTGAACAGATGAAAGTTCCAAATATGCCCGAAGTCTCCATCACCGTAATGAGACCGACTGGTGAGACCCTACACTCCCGTCAAGGCATTCAGCAGCTTGCCTCCAAGGACTGTCTTATCTGCGGACGCTCTTACAGATATTCCCATAATGCCCGCAGGCATGAACTAGCAGCACACAGCTTCGACCGCTACACCAACAAAGTGACGAACAAGTCCAATCACTCAATTATGCAACCTAAACTCAGGCCCAACCCGTTCAATCCAAAAGCCAGGCTTATGCCTAATCATATCAGCCATAAATTACAACTCATGCCCAAAAATCCCGCCAAAATGCTACAGAAATCCACCCCACCGAAACCAATACCCATAAAAGCTTCTAAAACGCAACAAAATAACTTACCATACCCTTTACGCATTAAAGCGCTCAAAGACTTACAGATAAAGAAGAAAGAGCCACAGATTTTGAAGACTTTGCTCACTGCTAAGCCGGAAGTATTAGTTTCGGAACCTGAGATAATGAACTCGGGACCAGAAAGTCCGGAAACCTTGATATCAGAGCCGGAAATTGCGTCATTCCAGGTAGAAGCTATTCTCTCGGAGCCTAATGAATATGATCAAAATCAAGAAGATGGTGAAATGGAACAccatagtcaaagtcaaaattacgATACTGTGGACATGGAATCAGATCACGAGATTGAAATCGCTCGTCAACAGGAAAACGAAGGAGACAATTTGGAAAACATCAAAAATGAAAATGGGCACCTTGAAGAAAACCATGTCGATAACGATGAAAAGCAGATCGAGAGTGACAATGATGTTGAGCTGGATAACGGCGACAGTCAGGGATTGATGGAGATTGATGATGCTCCAGAAGCTCACGTCGGTGAAGACGAAGGTAAAGAAGAGGAAACTAATCTAGAAGGCGAAATTGACGAGCAGGAGGTCAATCCTGAAGCTGATGACAATGATGAGGAGGAATTAATTCTGCCAACTCCCGTAGTTGAATTGAACGAAATGCAAAACAATTCGTGTAGTGAGCTGAATGATGAAGACGAAGAATTAGACGAAACGGCCGATATCAGCGAAACCACAGAGCAAGATCCAAAAGTCCTCGATCCTGACAAAACATATGTCACCAAAGTACAAAGAGATTTTATCGTCAAGTATCGCAACGTCATACAACAAATCAATACCAAACGTTGTCTCTGCTGCGATAAGACATACCCACGCAGGAAAGCAGTTGTTCAGCATTTACAGAAAAATGGACACAAGGTGCCTAAGCACACCTGTTACAACTGCGTGATTACGTTTACTCATATCGGCGCACTCCTAAGCCATATGAGACAGAACGCCTGTACGGATCTTTGGAAAATTATATATGACGAAAACGGTATTTCTGATGACATGGTTTTGGAAGATGAGCCTAAAAATAAGATTCAACCTAAAGATATTTTCAACGCCCGATCTTACGCGTGCCGTCTTTGTCCGGCTAAGTTCCAATTAAAGCAGTCTATAATGAAACACGTATTGGATGTGCATGAAGACGGCCAGTCTGCAGTGCCACTCGGCTGCGTTCACTGCCGTGCGAGCTTCAAAGACAGAACTTTGCTCAAGAAACACATTCGCGTCGGTGAATGCACAGTTTACATCCATTGCGATTTGTGTTCTGATCAATTTTCTAACATGCAAGACTTCAGCGAACACGCCTTATCAGCACACGCTGACCACTTCGAGAAGGCAGGCAACCAAAACAAATGTATCGACGGCCGGGCAACAGACTGCTCGATTTGCGGCAAGAAAAACAGTAACTACTTGAATCTAGTTAAACATTTGAAATTTGTTCACAATGAAGATAGACCTCATTACTGTCAAAATTGTGACGCTAAGTTCGAACTAGCTGCCGACCTTAACAATCATATTTATGTGGAGCATTCAAATCAAGCGTTGGGTTTGCAGCCTCAGGAGCCTAATATGTCCCTTGTGAAAGAAGAAGCCGAGGAGTATCACTACTCGTGCACAGAATGTAACGCCATATTCGAAACTGTCGACGCTTGGACGGACCATCAAGTTGCGGAACACAATCAAGTCGCCCATCATTGCGACCAATGCGACAAAAAGTTTTTGCGACCTTCTGAACTCGCTGAACACAAAAATACCCACTTGAGAGTTAAGTTCTATCCTTGCAGTGTATGCCCGAATTCATACAGTACACCTCAGAAGCTGTCTGATCATGTGCAGCAAGTCCACCCCGGAGCGGGCAATAATACCAGTGCAGAGACAGAATTTTTCTGCGATATATGCATCCGTTCATTCAAAAGTCGTCAGGCGTTTTCAAATCACATGCGCATCCACGCTAAAGTGCCGTCTACGAACAGAAAACCAGGTGAACCTAAAGGATTCGATCCGCGTATTATCGGAAAACCAATTAAACAATTTACCATAGTTCAACCTGGCTTTCTCAACTTCAAGCCAAATGCAAATGTTCCTAACGCGCCTTACTCATGTGATATTTGTGGTAAAGGCTTCATGCATAAGAAGAATATATGGAAACATAAGAAAGTCCTGCATGCGGATATCGTAAATGATAGGAACGATAGTGAGGATAACACTATGCATGCCTCTACAGAAGATGACGATTACAATCCTGATGAAAATGGAGCACTATCCACACCACAATTTGACAGCTTCAACTTCTCTAACTTTACGAGTAACAGCACACCAATAAAGTCTGAGGCTCAGTCGGATATGCCATATTCATGCGAATTGTGCTTCAAGCGATTCCCGCTTAGAACTAGTTTGTGGAAGCATAAACGTGCTAAACACGGTATCGTGAACCCTGGTGGCGGGGGCAATGAGACACACGCGACGCCGGGAGAGAGTGGCAGATCTAGCTGCACAATTTGTAAAATCACTTTTGCGGACAAGAAATCATATTATCGTCATAGGAAGAACGTTCACAAAACTGCTACACAGATGTGTAAGATTTGCGGAAAACCGCTCAATTCTACTTTGGAGCTGTATGAACATCTGAAAGCTGCACACGCTCGAGAATTGCTGGGCTACAACGCTAACCAAGGCTCGATTAAAACTCAACCAGACACTTCTCAAGATCTTGATGTTGACTATGATAACGAGCCGGAGCCGGCAGATCCTGGCCTGGACTATCAAGCCCGGTACCCGTGCGATACATGCGGCAAGCAGTTTGTGGGTCTGCTGGCGTTACAGAACCATCAATGTATAAATCAGATTACTTCGCAACCGCAGACTTTCGACTGTGAAATTTGCCACAAAAGTTACACTTCAATCGCCGCCTTGAAAAGTCATCGTGGTTGGCATTTGCGCTCTCCCGACGGTAAAGCCGCTGCCAACAACAGCGGTCTTTGGATGCCTCAGCACAAAGTGACGAGTAAAGTCAGCAAGCACGAGATCGTTGACGCGGTTCAGTTGGCTCGGGTCTCGCATTCGACTCCCACCGCTGCCTTCACTGCCAAAAGGAGATTACCGCCGGAGGTGGAAGTGACTGTCGTCAATCCAAATAAGAAGCTGCGCTCCGATGACTCCGTCGAAATGGATCAAAGCAACGACGCATTAGAAGGGAGATACTGCACAATTTGCGACAAAGAGTTCACTAAACGTGCCGCTTATCAGCGTCACATGGATGAGGTCCATCAGCCAAACTCTGTGTTTTGTCCGGTATGTGACAGGAGTTTCACGAGGAAATCGACGCTTCTCGTGCATATGAAGAAGCATTACGAAAGCGGGGAGGGTACGTCCGCCGCTGGGCAAGTAGAAGACGATGGTTACCCGTGTGAAGTGTGCGGTGCGGTCTTTGATACAGAGAAGTCATTGAGGGGTCATATGGCGAGGCATCACGCGAATGATTCGGGGGAATCAGAGGACGAGGGCAATGCGCCTGCTGCTCCGCCAGGCGAGTTCACTTGCGGACAGTGTGGAGACGGCGTGGCCAGTCCTCGTGATTTGCTGGCCCACCGTTCGATGCACGCAACTCCCACAAAATTCTTCTGCAACATTTGCAAAGTATATTTCGCTCGTGCGCTAGACCTATCGTCGCACACGCGTGCTCGTCATTCCGACAACGAAAAAGTGTTCTTCCCCTGTGCCATGTGTGACCGCTTCTATATGAACAAGAAGAGTTTACAAAGACATATTGAGATGGCACATTGA
Protein Sequence: MSVNYDRVCRLCLSSRGELLPIFPTTSSDDSESPVLVSKIKDCVSVQINQNDELPTNVCRKCMDNVNNWHIFKTVCEKTQNKLQSLIKKDGSLLEEVKIKSEPLSDEAYDDGVLIDGSYPVIENTTSASKLQPEGPPILASLGLTPRSDKGVESENNEDEYYEEEMKHQVPEQMKVPNMPEVSITVMRPTGETLHSRQGIQQLASKDCLICGRSYRYSHNARRHELAAHSFDRYTNKVTNKSNHSIMQPKLRPNPFNPKARLMPNHISHKLQLMPKNPAKMLQKSTPPKPIPIKASKTQQNNLPYPLRIKALKDLQIKKKEPQILKTLLTAKPEVLVSEPEIMNSGPESPETLISEPEIASFQVEAILSEPNEYDQNQEDGEMEHHSQSQNYDTVDMESDHEIEIARQQENEGDNLENIKNENGHLEENHVDNDEKQIESDNDVELDNGDSQGLMEIDDAPEAHVGEDEGKEEETNLEGEIDEQEVNPEADDNDEEELILPTPVVELNEMQNNSCSELNDEDEELDETADISETTEQDPKVLDPDKTYVTKVQRDFIVKYRNVIQQINTKRCLCCDKTYPRRKAVVQHLQKNGHKVPKHTCYNCVITFTHIGALLSHMRQNACTDLWKIIYDENGISDDMVLEDEPKNKIQPKDIFNARSYACRLCPAKFQLKQSIMKHVLDVHEDGQSAVPLGCVHCRASFKDRTLLKKHIRVGECTVYIHCDLCSDQFSNMQDFSEHALSAHADHFEKAGNQNKCIDGRATDCSICGKKNSNYLNLVKHLKFVHNEDRPHYCQNCDAKFELAADLNNHIYVEHSNQALGLQPQEPNMSLVKEEAEEYHYSCTECNAIFETVDAWTDHQVAEHNQVAHHCDQCDKKFLRPSELAEHKNTHLRVKFYPCSVCPNSYSTPQKLSDHVQQVHPGAGNNTSAETEFFCDICIRSFKSRQAFSNHMRIHAKVPSTNRKPGEPKGFDPRIIGKPIKQFTIVQPGFLNFKPNANVPNAPYSCDICGKGFMHKKNIWKHKKVLHADIVNDRNDSEDNTMHASTEDDDYNPDENGALSTPQFDSFNFSNFTSNSTPIKSEAQSDMPYSCELCFKRFPLRTSLWKHKRAKHGIVNPGGGGNETHATPGESGRSSCTICKITFADKKSYYRHRKNVHKTATQMCKICGKPLNSTLELYEHLKAAHARELLGYNANQGSIKTQPDTSQDLDVDYDNEPEPADPGLDYQARYPCDTCGKQFVGLLALQNHQCINQITSQPQTFDCEICHKSYTSIAALKSHRGWHLRSPDGKAAANNSGLWMPQHKVTSKVSKHEIVDAVQLARVSHSTPTAAFTAKRRLPPEVEVTVVNPNKKLRSDDSVEMDQSNDALEGRYCTICDKEFTKRAAYQRHMDEVHQPNSVFCPVCDRSFTRKSTLLVHMKKHYESGEGTSAAGQVEDDGYPCEVCGAVFDTEKSLRGHMARHHANDSGESEDEGNAPAAPPGEFTCGQCGDGVASPRDLLAHRSMHATPTKFFCNICKVYFARALDLSSHTRARHSDNEKVFFPCAMCDRFYMNKKSLQRHIEMAH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01209555;
90% Identity: iTF_01209555;
80% Identity: -