Pnap002299.1
Basic Information
- Insect
- Pieris napi
- Gene Symbol
- IBTK
- Assembly
- GCA_905475465.1
- Location
- FR997694.1:13852020-13866450[-]
Transcription Factor Domain
- TF Family
- BTB
- Domain
- zf-C2H2|ZBTB
- PFAM
- PF00651
- TF Group
- Zinc-Coordinating Group
- Description
- The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 1.1e-14 4.3e-12 46.6 0.1 6 79 535 606 530 613 0.88 2 4 7.3 2.9e+03 -1.1 0.0 84 108 678 702 670 704 0.81 3 4 5.2e-11 2.1e-08 34.7 0.0 9 106 728 829 722 833 0.81 4 4 2.4 9.5e+02 0.4 0.1 80 106 835 861 830 864 0.88
Sequence Information
- Coding Sequence
- ATGAGTAAGGCACCTGAAGCTGATTGCACAATTAAGTGTAAGTCTAGAAGTCACGGCCAGATCATAACAAGTGCTATCACTAAGAGATCTACAAGTGATGTATCTCTTGCAAGTTTTATTAGAGCAACTTGCAACAATTTCACTAAGGCGTTTGATTTTGAGGGCCGCACAGCTCTACATATGGCTGCGTCAAGAGGTAGAAACAATCTTATGCAATGGCTTATAAATCATTCATCAGAAGCATTTGTGAATGCTAAAGACAGGGAGTCTGGGTACACACCACTACATAGAAGTATATTTTATGGACAAGTACATACGGCTGTTGCGTTGATGAAAATAGGAGTATACCCAGATATTTTAGACAAAGATGACTACAAAGCCTTAGAGCATGCAATGCTTGACCGACAATACATCTGTAAAGTTGGGAATGAAATGCCTGGTGATGTCTATGTATGGGGAAGCAACACTAACTATACATTGGGTACTGGATCGCAGCAGTCAAAAAATTTGCCAGATCTCCTTTCTTGCTTCAGTAGGAGTAATGAGAATGTTAAGCAAGTCTGCTTAGGCAAATTCCATAGTGTATGGCTATGCGCATCTGGGTCCGTTTGGTGCGCCGGGCAACCGGCACGTGCCGGTGGCTCTGCGGCTACGGCGCTTCGCCCCACGCTATTGAGACTACCGGAGCCCTGTAAGGAGATAGCGTTGACGCTGACGTCTACAGTGTTCTTGCTGCAGAGTGGTCAGATGATCCAATACACCTTCAACAGTTCAGATAATACAACATCAACGTCGAAAGTGGGAACAACAAAATATCAAATTTCTCATCCAATTGGAGTTTGTGCGGGCCGGTCCCACGTTGTACTTTGGAACGCAAAGGGTGTGTACACATGGGGACAAAATGTGGGACAGTTGGGACATCAGGATAAATTTGTGCCGACACCAAAAAAGGTAGCGATATCTATGAATAGTAAAGAGGAGACAAAGTTTGAACTTGTTGACGCGTCGGATGCTGCGACGGTGGTCACAACCAGCCGTGGAGATGTTTATTTGCTGCATAAGTATATTTGCAAGAAAATCGCTGTAAAGCAAATAAATCTTCACCAAGTGCGCGTGGAAGCGAAAGTGACCGAGGCGGGGAGCTATTCTCGAGTTACGGTTCTTTTGCTTACAAATGTCGGGCAGTTGATGATATGGCAGGACACAATAAATAAACTGACGAGGTGCGTGTTTGGCCTCAATCACCAAATAAAAATAACACAAATGGCACTAACACACGATGCTTTATACTTCACAACTAAATATGGTGAAGCGTTCATTGGTTACATTTCTCGTAAAACTCCGTCAAAGAAAGAAGACACGCCCTTGAAGAGGGAGAAGGACGGCAAATCGATTGTCAATAGTTTAGAAAGAGACGACTACACTTCTGTCAAGATCGTCAAGATACCAAACGTGCATAGAGCTACGGCGATATCTGTGGACTGCGAGGGACTTAATTTTGCCTGTATACAGAATAAACCAACTTGCGGGCTACTATCAGTACCAGAACTTTCGCCATCTTGTCTCTCCAAGCACATGGAATCTTTATTTGAGACAGCAGCCGATGATGACATCTTACACGATGTCACGTTCAAGGTTGGTTCGAAACTTTTCCCCGCACACATGTTCATTATAGCCTCAAGTAGTGAACTTTTATACAAATTATATCAAGAGGCAACACTGATTGATGAAAAACCTATAATTGTATTAGAAAATGTTCACCCTGAAGTATTTGAAAGGATCGTAAAATATATGTATACGGGTTCATGTGATGTTGCCGAGTTGGGTCCGTGCAGTTTGAAGATAAGGAAGGAAGATTTGATTCCATATAAGAAAGAAAGAGAAGTCGATATTGATAATACAGAGGTCATTGAAAATCCATCGGAAATATCGGCTTTTGAGGTATACAAAGAGCAAGATAAGAGGAAAAATAACAAACGCCGACAGAATAATACAAACATACAAACACAGAGGCTGTACTGTGATCCTGTCAAAATGGTCCAAGCGTCTGCTAAGAGGTTACAAGTCATGGGCCTCCATAAACTTCTTGAGAAGTTCTACTACAAAAACGGTACAGTATGCCTCCGAGACAGTGCGACATACACTAAAAATACGGTGACATGGGACAGACAGACATACCCCGAATTAGTGGATACAAATGTGTGCTCAAAAGATGGTGTACTTTTATCTGCGCATAAGTGTGTGTTAGCCGCTCGCCTGGAGTATTTCAGTGGAATGTTCCTGCATTCTTGGACTGAGAGCAAAATGTTATCAAAAGTATCTATACCAATAAATCACAGCATACTTCTCCCGGTTATAAACTTTCTTTACACAGACACATGTCCCGAAATAGATAGATCGGACAGCATTGACTTCATTTGCAGTATGCTTATTGTCGCTGACCAGCTTTTCATTGGTAGAATTCGTGAAATGTGTGAAGTTGCACTTGCCAACCTTGTGACTTTAAAAAACTGTGCTGAACTATGCCAATTTGCACACACCTATAATGCAACACAACTCAAACAATACTGCATGGAGTATATATCACTGAACATAGCTAATATTCTTGAAAACCGGACTTTAGATCTTTTAGAAGACGAATTACTGGAGGATATAAGTAAATACTACTGCAAATTCAATCCTATAATGTCATCAAGAATTATAACACCATTCTCAATTGCACCTACCGATGAAACGGTGGAGGAAATAGCTAAAAATTTCTCCATAGATTTAAATTTCATTGATGAAGAGTATATCAAAGATACAAGTATTGTTGAAGTACCAACAAAAACAAGCAAAAGAGCAAAGTCCAAAAAAATTGAATATACAGAGAATGAGAAAGCTAGAATGAGATATGAATCTGTCAGTTCTGTATCATCTGATCTTAATGATTCGGGTGATATAACATTATCTCTAAAGGAAATTTCTAAAGAAAGTGATAAGTCAAACAGCAATTGGACACAAGTGTTATCACCACAACAGAAACTAGTACAGGCTCGTTTGAAAGCAATAACTTCTGCGAGAGACATCATGAATGAAACCCCAACAAATTCATTCACAAAATTGACTAAGAACGCACCAGTTGACACACCAAGTACATCCCAAATATTAACATCCCCAAAGGAATCATTTATTGACCATAGCCGGAGTTCTCATACGAATTTAGTTATAAGCCATGTTGGTCCAAAATTGTCCCAAAAGCAAAGAAAGAAATTGGCATCCATGGACAACCAGACTCTGCAGACCTTAGACAACTATCTAGTTAATAAGTTAACGATTGGATCGCCCCCTGATAAGCCAAAAAATCCTTGGAAAATTTGTGAAGCTCCAATTGCTAGCAGCAGCCCATGCAAACCTAAAAGTCTGGAATTTAATCAAATCCTTGCTGATCAGAAAAAACAAAAGGATGATTCTTCACGGATTATGACTAAATCTTTGACATTAACGCAGCTTGAAGATAAAGCCATTGAAGAATTAGAGAGATTTTATAACATACATGAAGTAGATGATGAATATATAACTGTAAGGCGCATTGAGCTTCAGGTGTCTTCACCACAGTGGATCAACACTGCCCCAAAGTGA
- Protein Sequence
- MSKAPEADCTIKCKSRSHGQIITSAITKRSTSDVSLASFIRATCNNFTKAFDFEGRTALHMAASRGRNNLMQWLINHSSEAFVNAKDRESGYTPLHRSIFYGQVHTAVALMKIGVYPDILDKDDYKALEHAMLDRQYICKVGNEMPGDVYVWGSNTNYTLGTGSQQSKNLPDLLSCFSRSNENVKQVCLGKFHSVWLCASGSVWCAGQPARAGGSAATALRPTLLRLPEPCKEIALTLTSTVFLLQSGQMIQYTFNSSDNTTSTSKVGTTKYQISHPIGVCAGRSHVVLWNAKGVYTWGQNVGQLGHQDKFVPTPKKVAISMNSKEETKFELVDASDAATVVTTSRGDVYLLHKYICKKIAVKQINLHQVRVEAKVTEAGSYSRVTVLLLTNVGQLMIWQDTINKLTRCVFGLNHQIKITQMALTHDALYFTTKYGEAFIGYISRKTPSKKEDTPLKREKDGKSIVNSLERDDYTSVKIVKIPNVHRATAISVDCEGLNFACIQNKPTCGLLSVPELSPSCLSKHMESLFETAADDDILHDVTFKVGSKLFPAHMFIIASSSELLYKLYQEATLIDEKPIIVLENVHPEVFERIVKYMYTGSCDVAELGPCSLKIRKEDLIPYKKEREVDIDNTEVIENPSEISAFEVYKEQDKRKNNKRRQNNTNIQTQRLYCDPVKMVQASAKRLQVMGLHKLLEKFYYKNGTVCLRDSATYTKNTVTWDRQTYPELVDTNVCSKDGVLLSAHKCVLAARLEYFSGMFLHSWTESKMLSKVSIPINHSILLPVINFLYTDTCPEIDRSDSIDFICSMLIVADQLFIGRIREMCEVALANLVTLKNCAELCQFAHTYNATQLKQYCMEYISLNIANILENRTLDLLEDELLEDISKYYCKFNPIMSSRIITPFSIAPTDETVEEIAKNFSIDLNFIDEEYIKDTSIVEVPTKTSKRAKSKKIEYTENEKARMRYESVSSVSSDLNDSGDITLSLKEISKESDKSNSNWTQVLSPQQKLVQARLKAITSARDIMNETPTNSFTKLTKNAPVDTPSTSQILTSPKESFIDHSRSSHTNLVISHVGPKLSQKQRKKLASMDNQTLQTLDNYLVNKLTIGSPPDKPKNPWKICEAPIASSSPCKPKSLEFNQILADQKKQKDDSSRIMTKSLTLTQLEDKAIEELERFYNIHEVDDEYITVRRIELQVSSPQWINTAPK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00878963;
- 90% Identity
- iTF_01203362;
- 80% Identity
- -