Basic Information

Insect: Pieris mannii
Gene Symbol: IBTK
Assembly: GCA_029001895.1
Location: CM054827.1:1128371-1142303[+]

Transcription Factor Domain

TF Family: BTB
Domain: zf-C2H2|ZBTB
PFAM: PF00651
TF Group: Zinc-Coordinating Group
Description: The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 1.3e-15 4.7e-13 49.9 0.0 6 79 535 606 530 613 0.88

2 3 4.2e-11 1.5e-08 35.4 0.0 9 106 728 829 722 833 0.82

3 3 2.9 1e+03 0.5 0.1 80 106 835 861 828 864 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	1.3e-15	4.7e-13	49.9	0.0	6	79	535	606	530	613	0.88
2	3	4.2e-11	1.5e-08	35.4	0.0	9	106	728	829	722	833	0.82
3	3	2.9	1e+03	0.5	0.1	80	106	835	861	828	864	0.88

Sequence Information

Coding Sequence: atgagtAAGGCACCTGAAGCTGATTGCACAATTAAGTGTAAGTCTAGAAGTCATGGCCAAATCATAACAAGTGCTATCACTAAGAGATCTACAAGTGACATATCTCTTGCAAGTTTTATTAGAGCCACTTGCAGCAATTTCACTAAGGCTTTTGATTTTGAGGGCCGCACAGCTCTGCATATGGCCGCATCAAGGGGCAGAAACAATCTTATGCAATGGCTTATAAATCATTCATCAGAAGCATTTGTTAATGCTAAAGACAGGGAGTCTGGATACACACCGCTACATAGAAGTATATTTTATGGACAAGTACATACTGCTGTTGCTTTGATGAAAATAGGAGTATACCCAGATATTTTAGACAAAGATGACTACAAAGCGTTAGAGCATGCAATGCTTGACCGACAATACATCTGTAAAGTTGGGAATGAAATGCCTGGTGATGTCTATGTATGGGGAAGCAACACTAACTATACATTGGGTACTGGATCGCAGCAGTCAAAAAATGTGCCTGATCTCCTTTCTTGCTTCAGTAGAAGTAATGAGAATGTTAAGCAAGTCTGCTTGGGTAAATTCCATAGTGTATGGCTATGCGCATCTGGATCCGTTTGGTGCGCCGGACAACCGGCACGTGCCGGTGGCTCTCCGGCTACGGCGCTGCGGCCCACGCTTTTGAGACTACCGGAGCCCTGTAAGGAGATAGCATTGACGCTGACGTCTACAGTGTTCTTGCTACAGAGTGGTGCGATGATCCAATACACCTTTAACAGttcagataatacaacatcaTCGTCGAAAGTGGGaacaacaaaatatcaaatctCTCATCCAATTGGAGTTTGTGCGGGACGGTCCCACGTTGTACTTTGGAACGCAAAGGGTGTGTACACATGGGGACAAAATATAGGACAGTTGGGACATCAGGATAAATTAGTGCCGACACCAAAAAAGGTAGCGATATCTATGAATAGTAAGGAGGAGACAAAGTTTGAACTTGTTGACGCATCGGATGCTGCGACGGTGGTGACAACCAGCCGTGGAGATGTTTATTTGCTGCATAAATATATCTGCAAGAAAATCGCTGTTAAgcAAATAAATCTTCACCAAGTGCGCGTGGAAGCGAAAGTTAGTGAGGCGGGGAGCTATTCTCGAGTCACGGTTCTTTTGCTTACAAATGTCGGACAGTTGATGATATGGCAGGACACAACAAATAAACTCAccagatgCGTGTTTGGCCTCAAtcaccaaataaaaataacacaaatgGCGCTAACGCACGACGCTTTATACTTCACGACTAAATATGGTGAAGCGTTCATCGGTTATATTTCTCGTAAAACTCCGTCAAAGAAAGAGGACACGACCATGAAGAGAGAGAAGGACGGCAAGTCGATTGTCAATAGTTTAGAAAGAGACGACTATACGTCTGTCAAGATCGTCAAGATACCAAACGTGCATAGAGCCACGGCGATATCTGTGGACTGCGAGGGACTTAATTTTGCCTGTATACAGAATAAACCAACATGCGGGCTTCTATCAGTTCCAGAACTTTCGCCATCTTGTCTATCCAAGCACATGGAATCTTTATTTGAGACAGCAGCCGATGATGACATCTTACACGATGTCACCTTTAAGgcTGGATCGAAACTTTTCCCCGCGCACATGTTCATTATAGCCTCAAGTAGTGaacttttatacaaattatatcaagAGGCAACACTGATTGATGAAAAACCtacaattacattagaaaatgTTCACCCTGAAGTATTTGAAAggatcttaaaatatatgtatacggGTTCATGTGATGTTGCCGAGTTGGGTCCGTGCAGTTTGAAGATAAGGAAGGAAGATTTGATTCCATATAAGAAAGAAAGAGAAGTCGATATTGATAATACAGAGGTCATTGaaaatccATCGGAAATGTCGGCTTTTGAAGTATACAAAGAGCAAGATAAGAGAAAGAATAACAAACGCCGACAGAAcaatacaaacatacaaacacaGAGGCTGTACTGTGATCCTGTTAAAATGGTCCAAGCGTCTGCTAAGAGGTTGCAAGTCATGGGCCTGCATAAACTTCTTGAGAAATACTActaCAAAAACGGTACAGTTTGCCTCCGAGACAGTGCTACATACACTAAAAACACAATGACATGGGACAGACAGACATATCCCGAATTAGTGGATACAAATGTGTGTTCAAAAGATGGTGTGCTTTTATCTGCGCATAAGTGTGTGTTAGCCGCTCGCTTGGAGTATTTTAGTGGAATGTTCCTGCATTCTTGGACTGAGAGCAAAATGTTATCAAAAGTAACTATACCAATAAATCATAGTATACTTCTCCCGGTTATAAACTTTCTTTATACAGACACATGTCCCGAAATAGATAGATCAGACAGCATTGACTTTATCTGCAGTATGCTTATTGTCGCTGACCAGCTTTTCATTGGTAGAATCCGTGAAATGTGTGAAGTTGCACTTGCCAACCTTGTGACATTAAAAAACTGTGCTGAACTTTGCCAATTTGCACACACCTATAACGCAACACAACTCAAACAGTACTGCATGGAGTATATTTCTTTGAACATAGCTAATATTCTTGAAAACCGGACTTTAGATCTTTTAGAAAACGAATTACTGGAGGATATAAGTAAATACTACTGCAAATTTAATCCTATTATGTCGTCAAGAATTATAACACCATTCTCAATTGCACCTACTGATGAAACAGTGGAGGAAATTGCTAAAAATTTCACCATAGATTTAGATTTCATTGATGAAGAATATATCAAAGATACAAGTATTGTTGAAGTGCCAACAAAAACAACCAAAAGAGCAAAgtctaaaaaaattgaatatacAGAGAATGAGAAAGCTAGAATGCGATATGAGTCTGTCAGTTCTATATCGTCTGATCTGAATGATTCGGGTGATATAACATTATCTTTAAAGGAAATTTCTAAAGAAAGTGACAAGTCAAACAGCAATTGGACTCAAGTGTTATCACCACAACAGAAACTGGTACAGGCTCGTTTGAAAGCAATATCTTCTGCAAGAGACATCATGAATGAAACCCCAACAAATTCATTCACAAAATTGACAAAGAACCCACCAGTTGACACACCAAGTACATCCCAAATATCAACATCCCCAAAAGAATCATTTATTGACCATACCCGGAGTtctcatacaaatttagttataaGCCATGTTGGTCCCAAATTGTCCCAAAAGCAAAGAAAGAAATTAGCATCAATGGACAACCAGACTCCGCAGACATTAGACAACTATCTAGTTAATAAGTTAACACTTGGATCACCCACGGATAAGCCAAAGAACCCTTGGAAAATTTGTGAAGCTCCAATTGCTAGCAGCAGCCCATGCAAACCTAAAAGTCTGGAATTTAATCAAATCCTTGCTGAtcagaaaaaacaaaaagatgATTCGTCACGGATTATGACTAAGTCTTTGACATTGACCCAGcttGAAGATAAAGCCATTGAAGAATTGGAGAGATTCTATAACATACATGAAGTAGATGATGAATATATAACTGTAAGGCGCATTGAGCTTCAGGTGTCTTCACCACAGTGGATCAACACTGCCCCAAAGTGA
Protein Sequence: MSKAPEADCTIKCKSRSHGQIITSAITKRSTSDISLASFIRATCSNFTKAFDFEGRTALHMAASRGRNNLMQWLINHSSEAFVNAKDRESGYTPLHRSIFYGQVHTAVALMKIGVYPDILDKDDYKALEHAMLDRQYICKVGNEMPGDVYVWGSNTNYTLGTGSQQSKNVPDLLSCFSRSNENVKQVCLGKFHSVWLCASGSVWCAGQPARAGGSPATALRPTLLRLPEPCKEIALTLTSTVFLLQSGAMIQYTFNSSDNTTSSSKVGTTKYQISHPIGVCAGRSHVVLWNAKGVYTWGQNIGQLGHQDKLVPTPKKVAISMNSKEETKFELVDASDAATVVTTSRGDVYLLHKYICKKIAVKQINLHQVRVEAKVSEAGSYSRVTVLLLTNVGQLMIWQDTTNKLTRCVFGLNHQIKITQMALTHDALYFTTKYGEAFIGYISRKTPSKKEDTTMKREKDGKSIVNSLERDDYTSVKIVKIPNVHRATAISVDCEGLNFACIQNKPTCGLLSVPELSPSCLSKHMESLFETAADDDILHDVTFKAGSKLFPAHMFIIASSSELLYKLYQEATLIDEKPTITLENVHPEVFERILKYMYTGSCDVAELGPCSLKIRKEDLIPYKKEREVDIDNTEVIENPSEMSAFEVYKEQDKRKNNKRRQNNTNIQTQRLYCDPVKMVQASAKRLQVMGLHKLLEKYYYKNGTVCLRDSATYTKNTMTWDRQTYPELVDTNVCSKDGVLLSAHKCVLAARLEYFSGMFLHSWTESKMLSKVTIPINHSILLPVINFLYTDTCPEIDRSDSIDFICSMLIVADQLFIGRIREMCEVALANLVTLKNCAELCQFAHTYNATQLKQYCMEYISLNIANILENRTLDLLENELLEDISKYYCKFNPIMSSRIITPFSIAPTDETVEEIAKNFTIDLDFIDEEYIKDTSIVEVPTKTTKRAKSKKIEYTENEKARMRYESVSSISSDLNDSGDITLSLKEISKESDKSNSNWTQVLSPQQKLVQARLKAISSARDIMNETPTNSFTKLTKNPPVDTPSTSQISTSPKESFIDHTRSSHTNLVISHVGPKLSQKQRKKLASMDNQTPQTLDNYLVNKLTLGSPTDKPKNPWKICEAPIASSSPCKPKSLEFNQILADQKKQKDDSSRIMTKSLTLTQLEDKAIEELERFYNIHEVDDEYITVRRIELQVSSPQWINTAPK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00878963;
90% Identity: iTF_01203362;
80% Identity: -