Basic Information

Gene Symbol
Gzf1
Assembly
GCA_905332375.1
Location
CAJOBZ010000006.1:920278-927444[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.00054 0.033 14.5 0.5 2 23 71 92 70 92 0.97
2 12 0.017 1 9.9 0.7 2 23 99 121 98 121 0.95
3 12 0.082 5 7.7 0.2 2 23 129 151 128 151 0.93
4 12 0.0002 0.012 15.9 2.0 1 23 157 179 157 179 0.96
5 12 4e-06 0.00025 21.2 6.0 1 20 185 204 185 207 0.96
6 12 0.00098 0.06 13.7 0.9 1 22 213 234 213 234 0.97
7 12 0.036 2.2 8.8 1.3 3 19 252 268 251 273 0.92
8 12 5.1e-06 0.00032 20.9 1.4 1 23 594 616 594 616 0.97
9 12 6.6e-05 0.004 17.4 2.0 1 23 623 646 623 646 0.92
10 12 0.039 2.4 8.7 1.8 1 23 654 677 654 677 0.96
11 12 0.00016 0.0098 16.2 1.6 1 23 683 707 683 707 0.97
12 12 7.6e-05 0.0047 17.2 2.4 1 22 713 734 713 734 0.96

Sequence Information

Coding Sequence
aTGGAGtctaatatatctttttatagTTTACCAtttatagaTTCGGAAAATTCAGAATCGGGTTTATTTAGAAGAGGAAACGAATGTAATTTCGATATTCATAATCCACTCTCTTCGAGCGGCGCCTTGTTAGGAGGCGACGATGTCCTTGCACAATTTCTCACAGACGGTCCCCTCGAAGAACCCGATCTTAACGGCCCGACGACCTTGGTCtgtgaaatttgtaaaaagaAGTTCGACAATGCTAAGAAATATTATGGCCATTTACGAGTTCATTCCAAAGATAATTTGTGGGTTTGTGATAAATGTCCGAATCagaaattttcaattaaacaGAACCTTATGAAACATTATCTAACACATAAACCATTAGCTAGAGTATGGAAATGTCCACAATGTTCTATGGTTTTTGAAGCGCTTTGGCGTTTACAACAACATCttttttctaaacatttaaaCTACAGaccCCATAAATGTGATGTGTGTGATAAATCATTTCTCAAGGCCTCTGATTTGAAAAAACACAAAGACATTCATGATGgtttaaatagattttcttGCACCATATgtcataaaaaattcaaagataAATCAAATTTGAATCGTCACATGGTTTGTCATACTAAGGAGAAAAAATACCGTTGTTTGGGTTGTCAGAATAGATACTCTCAgctGGCTACATTAAAACGACATCAAAAAACATGTACTCAATTTGTAGACACAGCCAAAGACAAAACTACTAGAAAAAACTATTGTCGAGAATGTGGTATGTCTTTTCAGTATAAGAGTGCATTGTTGGAGCACTGTGTTAGACAACACACAGAAAGTGGAACagatacaaaacaaaatactgatggaaataaaattgttgaaaatattGTTGATGATATACTATCAGTTGAAGATGATTACATGACTATGTCGACAAACCatgatatattaaatacttttaataataatacaagttATACAAATGTTACTCCAGATGATAATTTGatgcaaatagaatttttaaaggaaatgaATCAACTACATTCCTTAGATGACGAGTTCCTTTATAATGATCTAGATTTTGACAGCTTACAAAATAGCCAAATCTTTAATATGAACACTAATGATATAGATTACAGTGGCAATGGAGAAATATTTGACTATACAATAGGTAGCAAGAGTATGGATCAAGATTTAATGAATGCTCTTGCAAGAAATGATAATTTACCCGaagatttgtttaatttaaacacgTTTCCTGATAGACCAGTCTTACCTCCCACTTTGCCTGATGAGTGTGCTACTATTTTCGAAAGCGATGTTGATTTAGAAGCGAGTACAAATTTAGCCGCAAATTTAAATCAGCTTATTGGGGAAAATACAGTGCAGTATATTTCTACTGAAGATGATGATACATTTATCATAAGCCTAAACAGTGAAATCGATGCCGAGAAATTACAAGATATGCTAAATATTGACGTTGAACTAGTCAATAGTGaagaaaaaatagaaatgGGTTTGTTAAAGAACGATTATGTAGTTAAACAAGAAAATAATCTTATGAATAACATTGTACCAGTCATAATTAAGGTAGAGCAAGACAACATAAACAACACAACAGGGACAAGTGagagtaatattaaaaaatataaaaatgctttaaataacaacatagttttaattaaaatagaagaGCAAGATAAAACCCGTAAAGTGGAATTCGATAaagagaatttaaatattaaagaaagtaCAGAGAAGtcatgtaataataaaaagccaGTGGAGTTCATTTGCAAGActtgtaataaagtttttaacaaAAAGGATAATTATAAATCTCACATAGCAATTCATAACCCGTCCCTTCGTCGCCATCGCTGTGACGTATGCGGCGTTCGCTTTAGTTATCGTTCAACACTTAATAAACATCACGCGGCCGCCCATCAGCCGCGAACTTTACCGGATCACACGTGCCCGCACTGCCCGTCACATTATCCCGCTGCATGGatgTTAAAACAACACATAGAGCGATCCCACGAGGGTATAACACGTTTCGAGTGCGACGCAGAAGGTTGCGGGAAGCGGTTCTTTAAGAAGTGCGATCTCGTGGTGCATCAACGgtaTCACACGGGCGAGCGACCATTTTCGTGCGACATATGCAAGCAGCGTTTTCCACACGTATCACATCTTAAAAGACATGAACGCACCGTCGACTGCACTAAGAGGTCAAATGCGTTTTTCCAAAAATCTCATCTTCCAACCAGTTTGGATGTCGTCACTTAG
Protein Sequence
MESNISFYSLPFIDSENSESGLFRRGNECNFDIHNPLSSSGALLGGDDVLAQFLTDGPLEEPDLNGPTTLVCEICKKKFDNAKKYYGHLRVHSKDNLWVCDKCPNQKFSIKQNLMKHYLTHKPLARVWKCPQCSMVFEALWRLQQHLFSKHLNYRPHKCDVCDKSFLKASDLKKHKDIHDGLNRFSCTICHKKFKDKSNLNRHMVCHTKEKKYRCLGCQNRYSQLATLKRHQKTCTQFVDTAKDKTTRKNYCRECGMSFQYKSALLEHCVRQHTESGTDTKQNTDGNKIVENIVDDILSVEDDYMTMSTNHDILNTFNNNTSYTNVTPDDNLMQIEFLKEMNQLHSLDDEFLYNDLDFDSLQNSQIFNMNTNDIDYSGNGEIFDYTIGSKSMDQDLMNALARNDNLPEDLFNLNTFPDRPVLPPTLPDECATIFESDVDLEASTNLAANLNQLIGENTVQYISTEDDDTFIISLNSEIDAEKLQDMLNIDVELVNSEEKIEMGLLKNDYVVKQENNLMNNIVPVIIKVEQDNINNTTGTSESNIKKYKNALNNNIVLIKIEEQDKTRKVEFDKENLNIKESTEKSCNNKKPVEFICKTCNKVFNKKDNYKSHIAIHNPSLRRHRCDVCGVRFSYRSTLNKHHAAAHQPRTLPDHTCPHCPSHYPAAWMLKQHIERSHEGITRFECDAEGCGKRFFKKCDLVVHQRYHTGERPFSCDICKQRFPHVSHLKRHERTVDCTKRSNAFFQKSHLPTSLDVVT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01205956;
90% Identity
iTF_01206794;
80% Identity
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