Basic Information

Gene Symbol
-
Assembly
GCA_941918875.1
Location
CALNXE010001733.1:100650-102197[+]

Transcription Factor Domain

TF Family
zf-LITAF-like
Domain
zf-LITAF-like domain
PFAM
PF10601
TF Group
Zinc-Coordinating Group
Description
Members of this family display a conserved zinc ribbon structure [3] with the motif C-XX-C- separated from the more C-terminal HX-C(P)X-C-X4-G-R motif by a variable region of usually 25-30 (hydrophobic) residues. Although it belongs to one of the zinc finger's fold groups (zinc ribbon), this particular domain was first identified in LPS-induced tumour necrosis alpha factor (LITAF) which is produced in mammalian cells after being challenged with lipopolysaccharide (LPS)[2]. The hydrophobic region probably inserts into the membrane rather than traversing it. Such an insertion brings together the N- and C-terminal C-XX-C motifs to form a compact Zn2+-binding structure [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 6e-12 1.9e-08 35.0 11.6 2 68 57 126 56 128 0.82
2 3 3.5e-05 0.11 13.3 0.9 1 23 156 178 156 184 0.88
3 3 2.6e-05 0.081 13.7 0.6 52 70 181 199 177 199 0.87

Sequence Information

Coding Sequence
ATGGCAACAACAACAACAACCAATGAACAAAAGCCAGCTAATGTAGAGGTGGTCATTGACAAAAAGGCCCAAAAGGCAGGCGAAAAAATGCTGCGTGCCCAAAGGGAACAAGAGATTTACAATAACTTTGCCACACCCCTAGTGGGCACTTACTTAAATTTAACCCAAGAACCGGCATTCATTAAATGTCCCAGTTGTGGCATAGAGGAAATGAGCGAAGTGGTTGAAGAACTGAAATGGTGGGCAACGGAAATTAATCGTTTTCTAGGATGTTTATTTGTAACTTTATGCTGTTGCTTTTGTCTGGATTATAGTCTGCCCTGTACATCTAGTGATCGTAATCATTATTGCAAAAATTGTGGCTGCTATTTCGGGCGGGCCATGAGAATTCCGCCACTAACGAAAATCAAAATGCCCATCATGCAGAGCGAAACTTTACCACCACCTGTGTATTTTGCTGTTGGTCCTCAGCCCCATGAGGTTTCCTGTCCCTTCTGTAAACAATACAGCAAAACGATTATGAAACGCTCCATATTGCGCTGTTCATTGCGCCGCCACTATTGCTCCCAGTGTGGTGAATATTTGGGCTCCTATAGACGTCCTCAATTGTAG
Protein Sequence
MATTTTTNEQKPANVEVVIDKKAQKAGEKMLRAQREQEIYNNFATPLVGTYLNLTQEPAFIKCPSCGIEEMSEVVEELKWWATEINRFLGCLFVTLCCCFCLDYSLPCTSSDRNHYCKNCGCYFGRAMRIPPLTKIKMPIMQSETLPPPVYFAVGPQPHEVSCPFCKQYSKTIMKRSILRCSLRRHYCSQCGEYLGSYRRPQL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00900215;
90% Identity
-
80% Identity
-