Pmel005678.1
Basic Information
- Insect
- Phyto melanocephala
- Gene Symbol
- ibtk
- Assembly
- GCA_941918875.1
- Location
- CALNXE010000539.1:97708-105940[-]
Transcription Factor Domain
- TF Family
- BTB
- Domain
- zf-C2H2|ZBTB
- PFAM
- PF00651
- TF Group
- Zinc-Coordinating Group
- Description
- The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 4.5 1.9e+03 -0.3 0.0 25 73 248 305 234 313 0.71 2 4 6.3e-11 2.6e-08 34.6 0.5 7 106 562 656 556 660 0.82 3 4 1.1e-16 4.6e-14 53.1 1.0 8 106 700 803 693 807 0.82 4 4 3 1.3e+03 0.2 0.0 77 109 808 838 792 839 0.81
Sequence Information
- Coding Sequence
- ATGTTTAATCCAAAAAATTATGAATACGATTGTACGCGCAAATGCCGTTTGAGTGCCCATGGTAATGCTATAACGTCTGCTTTGACCAAACGCTCCATTGATAATGAAAAATTAGCTGCATATGTGTCTAAGATTTGTTGTAATTATGCCGATATTTTAGATGATTTGGGACGATCGGCCGTACATGTCGCTGCTTCAGTAGATCGTTATGATATCCTAGAGTGGTTACTAAACCAGGGCTCCATTATAAGTGGCCGTGATTTTGAGTCTGGCAACAGTCCTCTGCATCGTGCTATATTTTATGGCTGCATTGACTGTGCCGTCCTACTGCTGCGTTATGGCGCCAGCTTAGATATTTTAAACGAAGATACCCGTTCTCCTTTGCAGCAAGTATGTCGCCTAAGCGATTATCCCACCAAGCACAAAGTAAATTCTAGCAATGAACTTTTAGTCTGGGGTTCCAATAAAAACTACAATTTGGGCGTTAATAATGACCAGGGCACAGAAAACTTACCACAAATGCTGGATTACTTTCGTAAGGAACAAATCTCCATACAATCTGTAGCTTTGGGCGCCTATCACAGTTTGTTTTTGGATAAGAAATCCAATTTGTATGCAGTGGGTCACGGCAAAGGTGGACGTCTGGGTACCGGTAATGAGAATAGCTTAAGCACACCCAAGAAAGTCAAGATACAATTGAAAAATTCTGATGAGGAAATTATTTGTATTAGTGCTTCGCGTAAACATTCATTGGTCTTAACCAATTATTCATTGGTTTTTGCATGTGGCCTTAATGAAAATCAACAGTTAGGCATTCGTGATGCTGGAGAAAAGTGTCTAAATTTTAAAGAAGTTTCAACTTTAAGAAACTGTAATGTGGAGAATCTACAAAAAGTTTTGGCCAGTGATTATCATTCGTTGGCCTATTCGGAACAGTGTCTTTATGTTTGGGGCACAAATCTGGGTCAGATGGGTATTGACGCAAATACAAAAACTGTGCAGATACCTAAATTGATGAAATTACCACCAAAAACTTTAATACAATTTGTTTACGCTAACAACACCGCCACTGCAGTTTTAACCAAGGATAATACCATAATATTATATTATAATTATAAAATGAAATCCATTAAAGCACCAAATTATGAGACTCTAAAGAGTATAGCTGTTATAGAGGGTGATAATGCCAAATCGGAAAAGGGTTCTGCAAGTGCTTTAAAATTGTTGATATTAACACAAACTAATGTGGTATTCCTATGGTATCATTTAACACAAAATTTTTATAGATGCTCATTCGCTGGCATTCGCTTAAGCCAAATTGACAAAGTTTTGTACAAAGGAAATCAGGTATTAATTCTCTCCCAAGGAGACATATATAAAGGCAAATGTCAGCAGGTTTCACTGCCGCCACATTACAACAATGAATTGTCTAGAAGTACTGGAAAAACTTTAACTAGCATTTGGTCACGCAGTGATAATCGTTCAGCAGAAATGGCTAAGGATTTTATGATACGCATTGAGCTACAGCGTATAATACAAATTGATCGCGCTACAGATGTTTTCTGTGATGGTGACTTTGCCTCCTTTGCTGTTCTACAGGAATCTCATGTTAAATACTTTAAATTGCCTGCCCTTAATCCCGTCGAGTATACATTTAAAAAACTTTATAATGATGTGTGTGAATTTGACGCCATACATGATGTAGTTTTTTATGTAGATTGCGATAAATTTCCTGCCCATAAATTTATAGTTCAAGCACGTGCACCTGGTTTAAGAGAATTTATTGCATCAAAAGATGAGAAGGAAGTGCATTTGAATTTTCAGCTTTTAACTGGAAAAATGTTTGAACTAATATTGAAGTTTATTTATTCAAACTATTTGCCTAATGAACAAGATCTTGATGATGTACAAAGTAGCTTACATACCGATAGTCCTGATGAGCTGAAGGATGTTTGTAAAATATTTTTGAATTTTGTCGAACAATTTCGTATTTCAAATTTGGCGAATTATTTAAAATACTACTTGCAGCAATCGCCTTTTTACTTGCCCCACATGGTAGATAAATCTAAATATCGCTTTAATCGCTTAAAACACACTGACTATCCACAATTTTATGATGTTCGAATTCTATGTGAAAATGACATAGTAATACCAGCCCATAAGTGCGTGTTAGTGGCACGTTTGGAATATTTTGAAATGATGTTTACACACACTTGGGCGGAGCAGACAACTATTAATCTATCCTCTGTTCCTATTGAATATATGCAGGCTATCATTGAGTTCCTATATAGTTCAGATGTTGAGCATTTTCGTAAACAACAATATCGTGAAACTTTTCTCTACAATATGATCGTGTTCTGTGATCAATTCTTTATTGAACGCCTAAGGAAGGTATGTGAAATTTTGCTATTGGACAAAATATCTATTAGGAAATGTGGTGATATGTTGGATTTTGCCTGTATGTATAATTGTGAGCTAATGAAAAGGGGTTGTTTGGATTTTATTTGCCAAAACTTAGCTAGGATTTTACTGCAAAAGACGTTGTACAATTGTGAGCCAGAATCTTTAAAATGTATCAATCAAAATTATCGCCAAATGTTTAAGCAAGTCTTTGATTATCGTATAATAACACCTGATTCTGAGGCTATTGATGATGACTGCTTGTGTAGTTTTGTGGAGGACTTTAGGGTGGACCTAAACTATCGTATGGATGAGGAGGAGCAACTACATTATAGAACGGCCCAAAAAACCAAAGCTAAAGAAAATAAAAGTAAATTATCTGCCAGACAATATGAAAGAGACGCTATTAGTTTGATGATGGAAACATTAAATGTGTCAGACAATACAGAAAGGTTACGTAGAGATTCGGAAAAATCAAAGGTCGTTGAAGAAGCCAAAGAAATGGCTAATAAGCTACAAAATGAAGCAAAGTCATGGATGAAGGTGATGGATAAGAAAGAAAATAGAAGAAAAACATCATTAGAGCCGGTATTAAAGGTCAATGAAATTATGAAACAAGAACAACCACCAACACCCAGTTATGTTAGTTTAAACAAGACGAAAGACACCTTGGCAGTAGCGGTAAAACTAAAAACTCCTGAAAAGAATATAAATAAATCGCTCTCGACTAGCCCAGCCTCTAAGCTATACAATATCAGTTTAGCTGAACTAACTACACCACCCAGAGAAAAACTTTCACAAAAACAACGCAAACGTCTAACATCAGAAAATTCAATTTTACAAAATTCTGAGCGAGCGCTATCAGATTTAGTTGAATATAAACCAGATACTGTGCCACAAACACCTAATGCTTGGGGTGTTGTCCCACAGTCTCCCACTTCTAACATGGATTCTGATACATTATATTCACCACCTACTGGCAGTTGGCTAGATCCATCATCATTTGCTAATAAGATGCGATCAAATACTAAAAACTCAAACACTTTGCCCTCTACCACGAATGCCAACAACAGCTTTAGCCAGATTTTGGCTGAAGAAAAACGCCAACGTGAATACTACGAACGTACTAAACACAAGTCTCTGGTCCTGACACAAATTGAAGAACAAGCTATGGCAGAACTGAAGCAATTCTATAATGTGGATAATGTTACTGATGAAATTATAACAATAGAAAGGAAATCCATACAACCCACaattaattttgccgtttggcaaagaaattaa
- Protein Sequence
- MFNPKNYEYDCTRKCRLSAHGNAITSALTKRSIDNEKLAAYVSKICCNYADILDDLGRSAVHVAASVDRYDILEWLLNQGSIISGRDFESGNSPLHRAIFYGCIDCAVLLLRYGASLDILNEDTRSPLQQVCRLSDYPTKHKVNSSNELLVWGSNKNYNLGVNNDQGTENLPQMLDYFRKEQISIQSVALGAYHSLFLDKKSNLYAVGHGKGGRLGTGNENSLSTPKKVKIQLKNSDEEIICISASRKHSLVLTNYSLVFACGLNENQQLGIRDAGEKCLNFKEVSTLRNCNVENLQKVLASDYHSLAYSEQCLYVWGTNLGQMGIDANTKTVQIPKLMKLPPKTLIQFVYANNTATAVLTKDNTIILYYNYKMKSIKAPNYETLKSIAVIEGDNAKSEKGSASALKLLILTQTNVVFLWYHLTQNFYRCSFAGIRLSQIDKVLYKGNQVLILSQGDIYKGKCQQVSLPPHYNNELSRSTGKTLTSIWSRSDNRSAEMAKDFMIRIELQRIIQIDRATDVFCDGDFASFAVLQESHVKYFKLPALNPVEYTFKKLYNDVCEFDAIHDVVFYVDCDKFPAHKFIVQARAPGLREFIASKDEKEVHLNFQLLTGKMFELILKFIYSNYLPNEQDLDDVQSSLHTDSPDELKDVCKIFLNFVEQFRISNLANYLKYYLQQSPFYLPHMVDKSKYRFNRLKHTDYPQFYDVRILCENDIVIPAHKCVLVARLEYFEMMFTHTWAEQTTINLSSVPIEYMQAIIEFLYSSDVEHFRKQQYRETFLYNMIVFCDQFFIERLRKVCEILLLDKISIRKCGDMLDFACMYNCELMKRGCLDFICQNLARILLQKTLYNCEPESLKCINQNYRQMFKQVFDYRIITPDSEAIDDDCLCSFVEDFRVDLNYRMDEEEQLHYRTAQKTKAKENKSKLSARQYERDAISLMMETLNVSDNTERLRRDSEKSKVVEEAKEMANKLQNEAKSWMKVMDKKENRRKTSLEPVLKVNEIMKQEQPPTPSYVSLNKTKDTLAVAVKLKTPEKNINKSLSTSPASKLYNISLAELTTPPREKLSQKQRKRLTSENSILQNSERALSDLVEYKPDTVPQTPNAWGVVPQSPTSNMDSDTLYSPPTGSWLDPSSFANKMRSNTKNSNTLPSTTNANNSFSQILAEEKRQREYYERTKHKSLVLTQIEEQAMAELKQFYNVDNVTDEIITIERKSIQPTINFAVWQRN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01194498;
- 90% Identity
- -
- 80% Identity
- -