Basic Information

Insect: Phortica variegata
Gene Symbol: e(y)2
Assembly: GCA_001014415.1
Location: JXPM01018158.1:3000-5732[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.016 1.3 9.6 0.2 3 23 285 306 283 306 0.96

2 10 7.4 6.1e+02 1.2 1.1 6 23 315 332 315 332 0.95

3 10 0.0049 0.41 11.2 5.2 1 23 338 361 338 361 0.94

4 10 5.1e-05 0.0043 17.4 1.9 1 23 367 389 367 389 0.98

5 10 1.1e-06 8.8e-05 22.7 4.9 2 23 398 420 398 420 0.97

6 10 0.00038 0.031 14.7 1.9 3 23 429 450 427 451 0.94

7 10 0.17 14 6.4 0.2 2 23 460 481 459 481 0.94

8 10 0.35 29 5.4 4.8 1 23 490 512 490 513 0.95

9 10 1.3e-06 0.00011 22.5 0.8 1 23 517 539 517 539 0.99

10 10 0.0081 0.68 10.5 5.1 3 23 547 568 545 568 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.016	1.3	9.6	0.2	3	23	285	306	283	306	0.96
2	10	7.4	6.1e+02	1.2	1.1	6	23	315	332	315	332	0.95
3	10	0.0049	0.41	11.2	5.2	1	23	338	361	338	361	0.94
4	10	5.1e-05	0.0043	17.4	1.9	1	23	367	389	367	389	0.98
5	10	1.1e-06	8.8e-05	22.7	4.9	2	23	398	420	398	420	0.97
6	10	0.00038	0.031	14.7	1.9	3	23	429	450	427	451	0.94
7	10	0.17	14	6.4	0.2	2	23	460	481	459	481	0.94
8	10	0.35	29	5.4	4.8	1	23	490	512	490	513	0.95
9	10	1.3e-06	0.00011	22.5	0.8	1	23	517	539	517	539	0.99
10	10	0.0081	0.68	10.5	5.1	3	23	547	568	545	568	0.96

Sequence Information

Coding Sequence: ATGATATGCCGTTTGTGTTTTATAGATCTTAAAGATTCTATAGACATATTCATTACGAGCGTTAATAGCAATAATCACGAAGTGGtacttttaattaagaaatatttacttatagaGTTAAAGCCGGGTGATCCAGTATCctcaaaaatatgcaaaacttgTTGGTCCACATTGAGAGATTTTCATGAGTTCTATCGGATGGTTACCGAGAAACAACAAGCAATACAGCTGAAGACCGAAGCAACAGAATGGATCGAGGCTTGGCAAGCGCCTGAATTGCAATTGATCGAAATACCTAAAGAAGCTATACTTGAAGAGTGTGACACACTAGGCGATGTCAAGGATGAGACGCTTTGTGAGCCAATAATCGATGCAAATCTACATGGTTATAACAACGAATGCCACGAAGCAACAGACACCAATACAATTGATGAGAACAATGACAAGGCATCTGATTGTGCAAGCGACGACACAAcgtcaataacaaaaaattgcgaAGATGTAACGTTAAAAGCTAAGAAATGTTTAGCCAAAAAGCGGCTAGATGCGCCAGCTTCAAAGACAACGAAAAGTCGCCGACAAAACACAAAGGGATCAACTTCGAAagtaaagacaacaaaatcattagCATCACCACCTTTGACGCGAAAGTTGCGTATGCGTTTACGTGTCATCAATGCAGAAACAATACCAACTGCAACAGCTGAAGAGACGCCGGCCAAACGCAAAGTGGGGAGGCCGCGTTTAAAATCAGTGCAGACACCAACGGCCGAATCACGTGCAAAATTTGATAGCCGCATGCGTATCAGCACAGATTTAGACAAGTACatcaatgaaaatgtaaagCTTGACTGTGCCGTTTGTAAGGTGCCACTTAAGGATTTTGGTGAGCTTAAGCGGCATTTTCGAACTGAACACAATTGCGTTGGCTACGCGATGTGTTGTAATAATCGCTACAGGAAACGATCGCTATACGTCGATCATCTGTGTTGGCACAAGGACCCAGAATACTTTTATTGTGATCAGTGTAAGAAAACATTTGTGAGTCGCAACTGTCTCCGTTTGCATAATTTGCGCTATCACACCGAAGAGATGACACATGAATGCAAACTGTGCCCAAAACGTTTCGCCAAAGGTTTTATGCTTACACAGCACATGCGTGTGCATCTTGCAGATCGTGAACGCACTGAACAATGCAAACACTGTGATAAGACCTTTCGAACGCCACACGAACTGCGTGCCCATGTGCGTCGCATGCATGACGAGTCTAATGCGCCAATTATTTGTGATATTTGTGGTGCTAACTTTCGtacgaaacaaaattttcacgTACATAAACGTGCCGTCCATCATGAGGGGCCGCAATTGCCCGAGGTGCAGTGTCCAGTCTGTGCGCGTTGGCTGCGTGATGAGAACAGTTTGCGCAAACACATGTACTTTCATCGTGAATCGGATCAGCCAGGTGCCTACAAGTGTAATGAATGTGGAGCTGTTAAGTCTTCACGTCATAAACTGACCTTTCACATACGCTATCATCACTCAAAGCGTTACAAGTGCACGCTGTGCGAAAAGGAGTTCAAACAATCAGTTACTTTAACTGAGCACATGGCCACACATACTGGTGTGGATTTGTATGGCTGTCCGTTTTGTGAGCGTACGTTTAAGTCGCACGCAAACATGCACaaccacaaaaagaaaatgcaccCAGATCAGTGGGTGCGTAAGTATTCCGTACCTAGTCGACCCACCGAAGAGATTGAATCGGGAAATGCATGTGATTCTACACAAAATCCGAACATGGAAATGACCAAAACAGTGTGCGATGCGCCTTGTGcatcaaattttaattcagACTCACTGCCCTTTTCGGATACAATGACAGTCTCGAATACCGTCGATCAGTACACCATTCTAACAGGCGACCGTGTAAAAATCAAGGATTTACTTTGCAATCGTTTAGTGGAGTGCGGGTGGCGCGATGAGGTGCGTCAACTATGTCGCAGTGCACTTGCCGAGAAAGGTAGCGGTACGTCAACAAACATGACGCCGGATCAACTCATTGCCGAGGTGACGCCACAAGCACGAGCATTAGTACCAGATGCCGTCAAAAAAGAACTACTCATGAAAATCAAGACAATTCTCACCGAGAAAATAGCCGAAGAAGAGGTGCAACAACGACAGGAGGGTGACGACGATTAG
Protein Sequence: MICRLCFIDLKDSIDIFITSVNSNNHEVVLLIKKYLLIELKPGDPVSSKICKTCWSTLRDFHEFYRMVTEKQQAIQLKTEATEWIEAWQAPELQLIEIPKEAILEECDTLGDVKDETLCEPIIDANLHGYNNECHEATDTNTIDENNDKASDCASDDTTSITKNCEDVTLKAKKCLAKKRLDAPASKTTKSRRQNTKGSTSKVKTTKSLASPPLTRKLRMRLRVINAETIPTATAEETPAKRKVGRPRLKSVQTPTAESRAKFDSRMRISTDLDKYINENVKLDCAVCKVPLKDFGELKRHFRTEHNCVGYAMCCNNRYRKRSLYVDHLCWHKDPEYFYCDQCKKTFVSRNCLRLHNLRYHTEEMTHECKLCPKRFAKGFMLTQHMRVHLADRERTEQCKHCDKTFRTPHELRAHVRRMHDESNAPIICDICGANFRTKQNFHVHKRAVHHEGPQLPEVQCPVCARWLRDENSLRKHMYFHRESDQPGAYKCNECGAVKSSRHKLTFHIRYHHSKRYKCTLCEKEFKQSVTLTEHMATHTGVDLYGCPFCERTFKSHANMHNHKKKMHPDQWVRKYSVPSRPTEEIESGNACDSTQNPNMEMTKTVCDAPCASNFNSDSLPFSDTMTVSNTVDQYTILTGDRVKIKDLLCNRLVECGWRDEVRQLCRSALAEKGSGTSTNMTPDQLIAEVTPQARALVPDAVKKELLMKIKTILTEKIAEEEVQQRQEGDDD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01195554;
90% Identity: iTF_01195554;
80% Identity: -