Pvar012814.1
Basic Information
- Insect
- Phortica variegata
- Gene Symbol
- Hr39
- Assembly
- GCA_001014415.1
- Location
- JXPM01007884.1:4220-8078[+]
Transcription Factor Domain
- TF Family
- SF-like
- Domain
- zf-C4|SF-like
- PFAM
- AnimalTFDB
- TF Group
- Zinc-Coordinating Group
- Description
- The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 5 2.3 1.3e+04 -4.9 1.7 139 163 26 50 20 62 0.53 2 5 0.19 1.1e+03 -1.3 1.3 82 153 208 282 137 303 0.61 3 5 3 1.8e+04 -8.1 14.0 34 158 268 418 257 453 0.41 4 5 1.6e-12 9.4e-09 35.1 6.0 1 137 520 679 520 692 0.62 5 5 7.7e-82 4.6e-78 263.4 0.3 183 408 683 899 677 899 0.94
Sequence Information
- Coding Sequence
- ATGTCCACAATTAAACCCGAGGTGATTAGTACCATTAGCGGTGGTAATGGCTTCCAGCTGCCGGTGAACATGAGCACGAGCACGAATACAGCATCagcaacgataacaacaacaaatacgcaACCGACGACGTCGACCACCACAATACGGAACAATATATCAGTGACGAACATTAAATGCGAAGTGGAAGACTTGGCATCGCCGAGTGGTAACATTGTGCCTGTGATAGCACGTACGCCCAGCTCGAATGGTGTGTCGTCTGGCAGTGGCATTGGTTGTGGCATACGCATACCGCTCTCAACGACTAGCATCAGCGATGGTATGACGGCAAAGGCCGATGATTCCGATTCTGAGGCCGAATTGACCAATATTGAGAATCTAAAGGTGACGCGTCGTGCGACGAGTAACGTTTGCGCCAACAGCAAAGATGCTACAGCGGATAGCCTAAATAAGAACGGGCCGCGTCCTATGTCTTGGGAGGGTGAACTCTCGGAGACAGAAACAATTGAAACGGAACAAATGGAAACGGACAGTTTATTGAGTAATGGCATACGGCATGGCATGCTTGGTGTAGCAGTGATCAAAAGTGAAGTTACCACTGGTGCCGTCAACACAACGTCGAGTGGGCAGCACTTGCAGCCAATAAAAACGGAACGGGAACACAATAGTGTTGGCATGTACACACCGACAGCGACACCAACACATAGCTATGGCAAACTGAAGCTGGCACCAACGCAAAGTGATCccattaatttgaaatatgaACCGAACCACAATGACGCTAACACTAACACAAATAGCACGATCAGTTCCACATCGGTGGCAGGTAGCATTAATTCGCCACTGTTGACGGTGCGTAATACTAAATGCAGCCAATTGCCATTGCCAGCAAATCCTAGTCCCGATTCCGCCATACATTCCGTCTACACGCACAGTTCGCCATCACAATCACCGCTCACATCGCGGCATGCACCGTATACACCATCATTGAGTCGCAATAACAGCGATGCATCGCACAGTTCATGTTACTCATACAGTTCCGAATTCAGTCCAACGCATTCGCCAATTCAGGCGCGTCATGCGCCACCCGCCGGTGCGCTCTATCCGGGCAGCTTTAATGGCGGTGCCCATCATCCGAATGTACTTTACCGGCCGCTTAATATTGAATCGGGCAATATCAATCATGAGGCACAAAATCTCAGCATGGATacgacgtcgtcatcatcaacgacaATGGCATCATGTACAGCACCGACTTCGTCCACCTTTGAGCCGGGTGGCAGTGGAGGGGCTTCCAGTTTGCCTGCCTCACCGGCTGGCATTTCACGGCAGCAGCTTATCAACTCGCCGTGTCCGATATGCGGTGATAAAATCTCTGGCTTCCACTATGGAATATTCTCGTGTGAATCGTGCAAAGGATTCTTTAAGCGCACCGTGCAGAATCGCAAGAattatgtttgtgtgcgtggCGGACCATGTCAGGTGAGCATTTCGACACGCAAAAAATGTCCAGCTTGTCGTTTCGAAAAATGTCTACAAAAAGGCATGAAACTCGAGGCCATCCGAGAGGATCGTACGCGTGGTGGTCGTTCCACCTATCAATGCTCCTACACGTTACCAAACTCGATGCTAAGTCCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTGTTAAGTCCCGAGCAGCAAGGCGCAGCGGTGGCTGCAGTAGCCGCTGCTGCCGCAtgtcaacaacatcagcagaaccaacaacaacagcagcagcaacgattGGACGCACTCAATGGCTATGCGCATTCTCCGCTAGCGGGGCAGGCAATAAAAGCCGAGCAGCAGGACTCATTGTCGTCATCACCAGCGACATATAATGGTGCTACCGCCTCACCGATCACAGCGGCCAACGTGCCCAACATACCCGCCTTGTTGCAGGAAATCATGGACGTCGAGCACCTGTGGCAATATAATGAAGCCGAATTGGCGCGTTTGAATCAACCTCAGACGGATACAGGCGCGAGTGCCGGTGCTTCGAATCCACAGATGACCAATCCACTGCTGGCCAGTGCTGGACTTGGTTCTCATGGCGAAAATGCCAATCCTGATCTTATAGCACATCTGTGTAAGGTTGCCGATCATCGTCTCTACAAGATTGTCAAATGGTGCAAAAGCCTGCCGTTGTTCAAGCACATTTCGATCGACGATCAAATCTGCCTGCTTATAAACTCGTGGTGTGAACTGTTGCTCTTCTCCTGCTGCTTTCGGTCTATTGATACGCCCGGCGAGATTAAAATGTCGCAAGGAAAAAAGATAACGCTCACTCAAGCCAAGTCACATGGACTGCAGaCCTGCATTGAACGAATGCTGAATCTGACAGATCATCTGAGACGTTTGCGCGTCGATCGCTATGAATATGTTGCAATGAAAGTGATTGTCCTACTGCAGTCAGATACTACAGAGCTGCAAGAGCCGGTCAAAGTGCGCGAGTGCCAGGAGAAGGCATTACAAAGCCTGCAGGCgtatacacacgcacattaTCCAGATTCGCCATCCAAGTTTGGTGAACTTTTGCTGCGCATACCTGATTTGCAGCGCACATGTCAATTGGGCAAAGAAATGTTGACCATCAAATCACGCGACGGAGGTGACTTCAACTTACTCATGGAACTGTTGCGCGGAGAGCATTGA
- Protein Sequence
- MSTIKPEVISTISGGNGFQLPVNMSTSTNTASATITTTNTQPTTSTTTIRNNISVTNIKCEVEDLASPSGNIVPVIARTPSSNGVSSGSGIGCGIRIPLSTTSISDGMTAKADDSDSEAELTNIENLKVTRRATSNVCANSKDATADSLNKNGPRPMSWEGELSETETIETEQMETDSLLSNGIRHGMLGVAVIKSEVTTGAVNTTSSGQHLQPIKTEREHNSVGMYTPTATPTHSYGKLKLAPTQSDPINLKYEPNHNDANTNTNSTISSTSVAGSINSPLLTVRNTKCSQLPLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQARHAPPAGALYPGSFNGGAHHPNVLYRPLNIESGNINHEAQNLSMDTTSSSSTTMASCTAPTSSTFEPGGSGGASSLPASPAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCQVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMLSPXXXXXXXXXXXXXXXXLLSPEQQGAAVAAVAAAAACQQHQQNQQQQQQQRLDALNGYAHSPLAGQAIKAEQQDSLSSSPATYNGATASPITAANVPNIPALLQEIMDVEHLWQYNEAELARLNQPQTDTGASAGASNPQMTNPLLASAGLGSHGENANPDLIAHLCKVADHRLYKIVKWCKSLPLFKHISIDDQICLLINSWCELLLFSCCFRSIDTPGEIKMSQGKKITLTQAKSHGLQTCIERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTTELQEPVKVRECQEKALQSLQAYTHAHYPDSPSKFGELLLRIPDLQRTCQLGKEMLTIKSRDGGDFNLLMELLRGEH
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01196042;
- 90% Identity
- iTF_01196042;
- 80% Identity
- iTF_01196042;