Basic Information

Insect: Phortica okadai
Gene Symbol: ftz-f1
Assembly: GCA_034638295.1
Location: CM067852.1:4708754-4722522[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.24 5.4e+03 -3.2 14.1 44 93 110 158 102 187 0.47

2 3 5.9e-20 1.4e-15 58.0 0.8 1 76 351 427 351 456 0.68

3 3 1.1e-72 2.6e-68 231.7 1.2 157 408 523 767 496 769 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.24	5.4e+03	-3.2	14.1	44	93	110	158	102	187	0.47
2	3	5.9e-20	1.4e-15	58.0	0.8	1	76	351	427	351	456	0.68
3	3	1.1e-72	2.6e-68	231.7	1.2	157	408	523	767	496	769	0.91

Sequence Information

Coding Sequence: ATGTTATTAGAAATGGAGCAACAACAGGGGACAGTATCCTTTATATCATCGCTCAATATGTCCCCATTTTCGATGCAATTAGATCAACAGCCCTCAAGTCCCGCGCTTGCAACAAATCAACAgagcggcggtggcggcggcggcggcaatgCAAATAAtcccaacagcaacaacaataataataataacagtagcaacaacaatgataatgATACAAATGCATTGAGCAATTCTGATACAGATTATGGCTCATATACATTACAATTGACAGGCGGCAGCAATAGTGGTCAGGGGGGCGGCGCCACTGGCGGTGCTGGTTCGAATagtcaacatcatcagcagcaacaacaacaacagcatcatcatcaccaacatcaacagcaacaacaacaaaaccaccaacaacactatcaacagcaacaacaacaacagcagcaacaacaacaaaatattgccaacaattcaaatttttcatattcgTACATTTATAACTTCGACTCACAGTACATATTTCCGACAGGCTATCAGGATACCACCTCATCGCATTCCCAGCAgagcggcggcggtggtggcagcGGCACCGGTGGCAGcgctggtggtggtggtggtctTAATAGTGCCTCACTACTCAATGGCGTTGCCGGTGGCGGTTCGGCTGGCAATTCAGCCGGTGGTTATATGTCTTTGTTACCGCCATCAGCCAGTTCGAGTGGCGGCCATTTGAGTGGCGTCGGTGGTGGTAATGGTGGCGCTGGCATTGCTGGCGGTGGCCCCGGTGGCACAAGTGCCTCGGCTGGCGTCTCCGGTGAATCAATTGATTTCAAGCATCTCTTCGAGGAGTTGTGTCCCGTGTGCGGTGACAAGGTCAGCGGCTATCATTACGGCCTGTTGACGTGCGAGTCCTGCAAGGGCTTCTTCAAGCGTACAGTACAAAACAAGAAGGTCTACACATGCGTCGCCGAACGTTCGTGTCACATCGATAAAACGCAACGTAAACGTTGCCCGTATTGCAGATTCCAAAAATGTTTGGAAGTCGGCATGAAATTGGAAGCTGTGAGAGCGGATCGCATGCGTGGCGGTCGCAACAAATTCGGACCGATGTATAAACGCGATCGGGCGCGGAAACTGCAAGTGATGCGGCAACGTCAATTGGCATTGCAAGCGTTACGCACCTCGATGGGCTCGACGGACATGAAGTCGACGCCGTTATCGCCGGGCTATCAACAAGCATATCCAAACATGAATATTAAGCAAGAAATTCAAATACCTCAGGTATCCTCACTCACACAATCGCCCGATTCATCGCCTAGTCCCATTGCGATCGCGCTGGGTCAGGTGAATGCCAATTCCGGTGGCGTGATAGCGACGCCAATGAATGGCAACAATGGCTCTGCCGGTGGCGGCaatggcggcggcagcagtggcggtggtggcggtagcggcggcggcagcaacaaTAGCGGTGACATCATCAATCGTGGCAGCAACAGTTGCCATGATGCTGGCACAGGATCTCTGCAGAATACGGCCGAATCGAAATTGtgTTTCGATTCGGGCACGCATCCATCAAGCACCGCCGACTCACTCATCGAGCCACTGAGGGTATCGCCAATGATACGGGAATTTGTGCAGTCGATTGATGATCGAGAATGGCAGACGCAACTTTTTGCGCTCTTGCAGAAGCAAACGTACAATCAGGTTGAGGTTGATCTCTTTGAGTTAATGTGCAAAGTACTCGATCAGAATTTGTTTTCACAAGTTGATTGGGCAAGGAATACGGTCTTCTTTAAGGATTTGAAGGTCGACGATCAAATGAAATTGCTGCAGCACTCATGGTCCGACATGCTTGTACTTGATCATCTGCATCATCGAATACATAACGGTTTGCCCGATGAGACGCAACTCAATAATGGACAAGTCTTTGATCTATTGAGTTTGGGACTATTGGGCGTGCCGCAATTGGGTGACTTCTTTAATGAGTTGCAAAACAAATTGCAGGATTTGAAGTTCGATATGGGCGACTATGTGTGTATGAAATTCCTAATTTTGTTAAATCCAGATGTGCGCGGCATCATTAACAAAAAGACAGTCTTAGAGGGTCATGAGAATGTGCAGGCAGCGCTGCTGGACTACACGCTCACCTGTTATCCATCTGTGACGGACAAGTTCAGACGCCTGCTGAACATACTGCCGGATATACATGCGATGGCGGCACGCGGCGAGGAGCATCTTTATTCAAAGCATTGCGCCGGCAGCGCGCCAACGCAAACGTTACTCATGGAAATGTTGCATGCCAAAAGGAAAGTGTAA
Protein Sequence: MLLEMEQQQGTVSFISSLNMSPFSMQLDQQPSSPALATNQQSGGGGGGGNANNPNSNNNNNNNSSNNNDNDTNALSNSDTDYGSYTLQLTGGSNSGQGGGATGGAGSNSQHHQQQQQQQHHHHQHQQQQQQNHQQHYQQQQQQQQQQQQNIANNSNFSYSYIYNFDSQYIFPTGYQDTTSSHSQQSGGGGGSGTGGSAGGGGGLNSASLLNGVAGGGSAGNSAGGYMSLLPPSASSSGGHLSGVGGGNGGAGIAGGGPGGTSASAGVSGESIDFKHLFEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNKKVYTCVAERSCHIDKTQRKRCPYCRFQKCLEVGMKLEAVRADRMRGGRNKFGPMYKRDRARKLQVMRQRQLALQALRTSMGSTDMKSTPLSPGYQQAYPNMNIKQEIQIPQVSSLTQSPDSSPSPIAIALGQVNANSGGVIATPMNGNNGSAGGGNGGGSSGGGGGSGGGSNNSGDIINRGSNSCHDAGTGSLQNTAESKLCFDSGTHPSSTADSLIEPLRVSPMIREFVQSIDDREWQTQLFALLQKQTYNQVEVDLFELMCKVLDQNLFSQVDWARNTVFFKDLKVDDQMKLLQHSWSDMLVLDHLHHRIHNGLPDETQLNNGQVFDLLSLGLLGVPQLGDFFNELQNKLQDLKFDMGDYVCMKFLILLNPDVRGIINKKTVLEGHENVQAALLDYTLTCYPSVTDKFRRLLNILPDIHAMAARGEEHLYSKHCAGSAPTQTLLMEMLHAKRKV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01363997;
90% Identity: iTF_01195329;
80% Identity: iTF_01195329;