Ppap004455.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Phlebotomus papatasi
Gene Symbol
-
Assembly
GCA_000262795.1
Location
Scaffold4:183215-210681[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 6.2e-06 0.00024 20.7 1.8 1 23 145 167 145 167 0.97
2 18 2.4e-05 0.00093 18.9 0.3 1 23 173 195 173 195 0.98
3 18 3.2e-05 0.0013 18.4 2.2 1 23 201 223 201 223 0.98
4 18 8.1e-07 3.2e-05 23.5 2.0 1 23 229 251 229 251 0.97
5 18 0.00022 0.0084 15.8 4.8 1 23 257 279 257 279 0.98
6 18 5.5e-05 0.0021 17.7 5.7 1 23 285 307 285 307 0.97
7 18 4.9e-07 1.9e-05 24.2 4.9 1 23 313 335 313 335 0.98
8 18 7.6e-08 2.9e-06 26.7 2.7 1 23 341 363 341 363 0.98
9 18 5.6e-05 0.0022 17.7 6.7 1 23 369 391 369 391 0.97
10 18 7.4e-05 0.0029 17.3 6.5 1 23 397 419 397 419 0.98
11 18 1.1e-06 4.4e-05 23.0 4.3 1 23 425 447 425 447 0.98
12 18 4.7e-06 0.00018 21.1 7.7 1 23 453 475 453 475 0.98
13 18 7.4e-05 0.0029 17.3 6.8 1 23 481 503 481 503 0.98
14 18 1.3e-05 0.00051 19.7 7.7 1 23 509 531 509 531 0.98
15 18 4.3e-05 0.0017 18.1 6.3 1 23 537 560 537 560 0.95
16 18 4.8e-05 0.0019 17.9 0.4 1 23 566 588 566 588 0.97
17 18 0.0062 0.24 11.3 3.9 1 23 598 620 598 620 0.98
18 18 7.4e-05 0.0029 17.3 1.3 1 23 626 649 626 649 0.96

Sequence Information

Coding Sequence
ATGGACTTCCGAGCTCCGGATGGATCAATATTGAAGATATCTAGTGGATTTCCTGAACCTGACATTGGTAAAGCTTTAGGAGTTGAAATGTATAAGGTAAATATCGAGGATCTCAGTCAATTTCTGTCATATCATGAGGTGTTCGGGAAGTTACCCAATGAGGCTGCACCAACAGCTTCGGGTATCAATATCGCCACCACGGCTGGAACCCTCAACATTGTTAGTAGTAGCAACAATGCAATGCAACCACCGCCACATCCACCTGTGGCCAATATTCCTGGAGACTCAGGACCACCATCTGTAAGTTCAGCACAACCGGCTATTGTGACATCAGTGCCGCCGGTGGATACCAAAATGGAGCCACCGAGTGTCCTGAATTCAGATCCCTCATTGCCCAATTCGGGGGAGAGTCCGGTCATTGTTCCGCTGTCGCATTCATGTGACATCTGCGGGAAGATGTTCCCCTTCCGTTACCAGCTCATTGTGCACAGACGCTATCACAATGAACGCAAACCATTTACGTGCCAGGTATGCGGACAGGGATTTTCCAACACGGCAGACCTGTCACGTCACGGAAAATCCCATATTGGTGGGCCAATGTTTATGTGCACGGTGTGTTTTCATGTGTTTGCAAATGATAGTAGCCTTGAGCGTCATATGAAGCGCCATGCGACAGATAAGCCATTTGCATGTACAATATGTCAAAAGACATTTGCTCGGAAGGAGCACTTGGATAATCATATAAGGAGTCACACAGGTGAAACACCATTTCGTTGCCAATACTGTGCGAAGAATTTCACACGAAAGGAGCACATGGTGAATCATGAGAGAAAGCATACAGGTGAAACACCGCATCGTTGTGATATATGCAAAAAATCATTTACGCGCAAGGAGCACTATGTGAATCACTATATGTGGCATACGGGTGAGACTCCGCATCAGTGCCAAGTGTGCGGGAAGAAGTACACGAGAAAGGAACATTTGGCCAATCATATGAGATCACATACAAATGAGACACCATTCAGGTGTGAGATATGTGGTAAATCGTTCACGAGAAAGGAACATTTTACCAATCACATTATGTGGCATACTGGTGAGACACCTCATCGTTGTGACTTCTGTTCCAAGACATTTACGCGCAAGGAACATCTTTTGAATCATGTGCGTCAGCATACAGGTGAATCACCACACAGGTGCACCTACTGCATGAAATCCTTCACGAGGAAGGAGCACCTTGTCAATCACATTAGACAACACACCGGAGAAACTCCATTTAAGTGCACCTACTGTACGAAGGCATTCACGAGAAAGGATCATCTGGTAAATCACGTGAGACAACATACGGGTGAATCTCCACACAAGTGCACCTACTGTTCCAAGAGCTTCACAAGAAAGGAACATTTGACAAATCATGTGCGTCAACATACTGGAGAATCACCCCATCGTTGTACATTTTGTATGAAGTCTTTCACGAGAAAGGAGCATTTGACTAATCACATTCGAATACATACGGGAGATTCTCCGCATCGATGTGAATTCTGCCAGAAGACTTTTACACGAAAGGAACATCTTACGAATCACTTGAGACAACATTCCAGCGAGAATCCTCATTGTTGCAATGTGTGCAATAAACCATTCACCAGGAAGGAACACTTGATTAATCATATAAGTCGATCCCATACTGGAGAACGGCCCTTTGCATGCAATGAATGCGGAAAATCGTTTCCACTGAAGGGAAATTTGCTTTTTCATCAGCGTAGTCACAACAAGGGTGCGGCTGCTGAGCGCCCTTTTCGCTGTGATTTATGCCCTAAGGATTTTATTTGCAAAGGTCATTTGGTGTCACATCGGAGATCTCATTCAGACGAAAAGCCATATGTCTGTATTCACTGTGGAAAGTCATTTGTGGAGAAGGGCAATATGCTGAGACACATTAAGAAGAATCATCCTCAAGCGGCACCAGTTGTTCTGGAGCCTCAAGTGATCATATCTCATCAAAAGGCCACCTTGCTGTCGCCACAGATAGCTACATCGAGGCCAATTTGTAGCACAACGGAGACAGTAAGTGCCCTACCTGTGACATCGACGATAACGTCCCATATCCTTCAGCATACAAATTCACAGACTGCATTGAGATTGTTGCAGAGCAGTGAACCACCACCTCCACCACCACCGCCAATTCCCGTCCATTCGCCGGAGAATTCGGTGGGGTTGCAGGTTAATGTTCACAATCACAATGCCGTCAATGCGCCGCCGCCACCGCATCAGCAGCTGAAGCCCTAG
Protein Sequence
MDFRAPDGSILKISSGFPEPDIGKALGVEMYKVNIEDLSQFLSYHEVFGKLPNEAAPTASGINIATTAGTLNIVSSSNNAMQPPPHPPVANIPGDSGPPSVSSAQPAIVTSVPPVDTKMEPPSVLNSDPSLPNSGESPVIVPLSHSCDICGKMFPFRYQLIVHRRYHNERKPFTCQVCGQGFSNTADLSRHGKSHIGGPMFMCTVCFHVFANDSSLERHMKRHATDKPFACTICQKTFARKEHLDNHIRSHTGETPFRCQYCAKNFTRKEHMVNHERKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGETPHQCQVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFTRKEHFTNHIMWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCTYCMKSFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHLVNHVRQHTGESPHKCTYCSKSFTRKEHLTNHVRQHTGESPHRCTFCMKSFTRKEHLTNHIRIHTGDSPHRCEFCQKTFTRKEHLTNHLRQHSSENPHCCNVCNKPFTRKEHLINHISRSHTGERPFACNECGKSFPLKGNLLFHQRSHNKGAAAERPFRCDLCPKDFICKGHLVSHRRSHSDEKPYVCIHCGKSFVEKGNMLRHIKKNHPQAAPVVLEPQVIISHQKATLLSPQIATSRPICSTTETVSALPVTSTITSHILQHTNSQTALRLLQSSEPPPPPPPPIPVHSPENSVGLQVNVHNHNAVNAPPPPHQQLKP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01192011;
90% Identity
iTF_01191360;
80% Identity
iTF_01192011;