Basic Information

Insect: Phlebotomus papatasi
Gene Symbol: Hr39
Assembly: GCA_000262795.1
Location: Scaffold449:51068-62634[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.015 83 1.7 0.8 68 194 92 214 61 221 0.58

2 5 0.85 4.7e+03 -4.1 7.4 34 170 209 350 202 354 0.55

3 5 7.3e-08 0.0004 19.2 0.0 1 27 420 446 420 457 0.88

4 5 0.0048 26 3.3 0.0 78 132 464 517 443 527 0.69

5 5 2.9e-77 1.6e-73 247.8 0.3 185 406 524 735 518 738 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.015	83	1.7	0.8	68	194	92	214	61	221	0.58
2	5	0.85	4.7e+03	-4.1	7.4	34	170	209	350	202	354	0.55
3	5	7.3e-08	0.0004	19.2	0.0	1	27	420	446	420	457	0.88
4	5	0.0048	26	3.3	0.0	78	132	464	517	443	527	0.69
5	5	2.9e-77	1.6e-73	247.8	0.3	185	406	524	735	518	738	0.95

Sequence Information

Coding Sequence: ATGGCAAGTACTAGCGAAAGTGGACGGGCTTCAAATATAAGTGTCACAAGCATTAACTGTGAACAAGATGACATCCAACAAAGTGCTCTTGAGGTTGCGACAGCGAATCAGGGAAATATTTCAGGAAGTGTACTGACAACAAGAGCCACTACCCCAAACCATTTTTACGGTGGTGGTGGAAGTATTCGGATTTCTGTACCCAAAATGGAAGAGTCTGATGAGTCTGATAATGAATTGCTAACAATTGAGGAGAGTGCTAAAGTGAATATGAGGAGCAAAAGTGAAAGCAATAATTCCAAGACTGCCCCCAGGCCAATGTCGTGGGAAGGTGAACTATCCGAGCATGAGGATGTAATGGATGTGGATAATGTGACTGGCAATGGGGATGGGTCAAAATTAGCTGAATATCCAGGAATTGATAAATTTAATCATCCAGTTATAAAAGTAGAGCAGCGAGATTTGGAAACTAAAGAGGAAAAGGCACCAGAAGAAGCAATTTCTCTCACAGCTAAAGTCTCTAATGAGACCACTAATGCAACTGCGATAGATTCTACTTCAAAGCACATAATTCAAAATGATGTGGTTAATTTGAAAGTGGAATCTAATTTACCAGAATTCAATTCATCTGTGCAGGCACCTCTTTTAGTGCGTTCAAAAACTACCCTTTTACCTGCAAATCCCAGTCCTGACTCAGCAATACACTCAGTGTACACACATAGCTCTCCAAGCCAATCACCTCTTACGTCGCGACATAATATATATACACCTTCCTTGAGTCGCAATAACAGTGATGCTTCACACAGTAGTTGCTATTCTTATAGTTCAGAATTCAGCCCAACACACTCCCCCATTCAAGGACGTCATAGCATGTATGGTAGCGTAGCTCTCAATGGTTCACCTTTGCATCATTCTGTGCTCTATAGACCAACAGTATATTCCGTTGATGCGGAATCTACAGCAAATAGGGCATGTTTTGATGATTCCACGACACTGGAGAGTGAGACATTACCATCAGCCGGAATATCAAGGCAACAGCTCATCAATAGTCCTTGTCCCATTTGTGGTGACAAGATCTCTGGATTCCACTACGGAATTTTTTCCTGTGAATCATGCAAGGGTTTCTTTAAGCGAACCGTTCAGAATAGGAAAAATTATGTTTGTGTCCGAGGATCAGCATGTCCAGTTACAATTGCGACGAGAAAAAAGTGTCCAGCGTGTCGATTTGAGAAGTGCCTTCAGCGCGGCATGAAACTTGAAGCAATTCGGGAAGACAGAACACGTGGTGGTAGATCCACATATCAATGTTCGTTTACACTTCCGGGTTCTATGCTTTCGCCATCCGTAATATCATCATCGGATTCTTCGGGATGTCATCAAAACTACCGGATGAACGTGCCACCACTGAAAGTTGAATCATGCGAGAGTGGCCCAATGAGTGGTTCTAAGCCACGTATACCATCACTTTTACAGGAAATTATGGATGTAGAATATCTTTGGCAGTACAACGAATCTGAACTGCTAAGACTTAACCAGCCAGCAGCAGTGACTGGTAGTGTACCGAATGGAACACAAGCAACGAATCCTCTGCTCGCTAGTGCTGGATTATCACAATCGGACAACTCAAATCCCGATTTAATCGCAAATTTATGCAATATAGCCGACCACAGGCTCTACAAGATTGTAAAATGGTGCAAGAGTCTTCCCTTGTTCAAAAACATTTCGATCGATGATCAAATTTGTCTCCTAATTAATTCATGGTGCGAATTGCTTCTGTTTTCGTGTTGCTTCCGGTCTATTTCGACTCCAGGCGAGATTCGAATATCACAAGGGAAATCTGTAACCTTGGCTCAGTCACGATCTAGTGGACTTCAGGCATGTGTTGAAAGAATGTTGAATTTGACTGATCATTTGAGGCGCCTTCGTGTTGATCGCTATGAATATGTGGCAATGAAAGTCATAGTTTTACTGCAATCAGACACATCAGAATTGAAGGAACCTGAAAAAGTGCGCACAAGTCAAGAGAAAGCCCTTCAGGCACTTCAGGCTTACACATTAGCTCATTATCCTGAATCACCTGCTAAATTTGGAGAGCTTTTGCTACGAATTCCTGAATTGCAACGGACTTGCCAGGTCGGTAAGGAAATGTTAACAATAAAATCAAAGGATGGTGATGAATTTGATCTACTTATGGAGTTATTGCGAGGATCCTTTTCGTGA
Protein Sequence: MASTSESGRASNISVTSINCEQDDIQQSALEVATANQGNISGSVLTTRATTPNHFYGGGGSIRISVPKMEESDESDNELLTIEESAKVNMRSKSESNNSKTAPRPMSWEGELSEHEDVMDVDNVTGNGDGSKLAEYPGIDKFNHPVIKVEQRDLETKEEKAPEEAISLTAKVSNETTNATAIDSTSKHIIQNDVVNLKVESNLPEFNSSVQAPLLVRSKTTLLPANPSPDSAIHSVYTHSSPSQSPLTSRHNIYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQGRHSMYGSVALNGSPLHHSVLYRPTVYSVDAESTANRACFDDSTTLESETLPSAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGSACPVTIATRKKCPACRFEKCLQRGMKLEAIREDRTRGGRSTYQCSFTLPGSMLSPSVISSSDSSGCHQNYRMNVPPLKVESCESGPMSGSKPRIPSLLQEIMDVEYLWQYNESELLRLNQPAAVTGSVPNGTQATNPLLASAGLSQSDNSNPDLIANLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSISTPGEIRISQGKSVTLAQSRSSGLQACVERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTSELKEPEKVRTSQEKALQALQAYTLAHYPESPAKFGELLLRIPELQRTCQVGKEMLTIKSKDGDEFDLLMELLRGSFS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01191234;
90% Identity: iTF_01191953;
80% Identity: iTF_01191953;