Parg008404.1
Basic Information
- Insect
- Phlebotomus argentipes
- Gene Symbol
- Aef1
- Assembly
- GCA_947086385.1
- Location
- CAMTYR010000037.1:11745703-11746164[+]
Transcription Factor Domain
- TF Family
- zf-GAGA
- Domain
- zf-GAGA domain
- PFAM
- PF09237
- TF Group
- Zinc-Coordinating Group
- Description
- Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 0.0012 3 7.5 0.1 21 46 19 44 5 46 0.91 2 4 9.5e-05 0.24 11.1 0.1 21 50 47 76 45 78 0.87 3 4 0.0016 4 7.1 0.1 21 51 75 105 72 106 0.88 4 4 0.00018 0.46 10.1 0.1 21 45 103 127 100 133 0.90
Sequence Information
- Coding Sequence
- ATGaaacgatcaatgtcacgagcactcacgcgcgtgattaagcttcacgggggcgccgagaagcccttccactgtcagatctgcgataagcagttccggcagctctccacactgatgaatcacatgaagatccacaccggcgagaagccgttcaagtgtcaggtgtgccagaagaacttccgccagtctagcactctcacgaatcacgtaaagattcacacgggcgaaaagcctttcgcctgcacgtactgcgaaaagcagttccggcaactgtcgacgctcacgaaccacctcaagatccacacgggcgagaagcccttcgagtgtgccgtgtgcaagaagcaatttcggcagtccagcacgctaaacaaccacattcgcgttcacgtgggcgaaaaAGTCATCGTCATTAAGAATGAACTCGACAGTCTCTATTGCACAGAGGTGAGTAATCTTTGTTAA
- Protein Sequence
- MKRSMSRALTRVIKLHGGAEKPFHCQICDKQFRQLSTLMNHMKIHTGEKPFKCQVCQKNFRQSSTLTNHVKIHTGEKPFACTYCEKQFRQLSTLTNHLKIHTGEKPFECAVCKKQFRQSSTLNNHIRVHVGEKVIVIKNELDSLYCTEVSNLC
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01192300;
- 90% Identity
- iTF_01191499; iTF_01192122; iTF_01192300;
- 80% Identity
- iTF_01191499;