Basic Information

Insect: Phlebotomus argentipes
Gene Symbol: Prdm14
Assembly: GCA_947086385.1
Location: CAMTYR010000037.1:3477536-3481339[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 24 0.2 7.8 6.7 0.2 7 23 41 58 41 58 0.92

2 24 7e-05 0.0027 17.6 0.7 1 23 64 86 64 86 0.96

3 24 0.00015 0.0059 16.5 0.5 3 23 93 114 92 114 0.96

4 24 0.0035 0.14 12.2 4.2 2 23 126 146 125 146 0.97

5 24 3.5e-05 0.0014 18.5 1.8 1 23 153 175 153 175 0.99

6 24 0.026 1 9.5 3.5 1 21 181 201 181 203 0.92

7 24 0.0042 0.16 12.0 5.6 2 23 212 233 211 234 0.95

8 24 0.00025 0.0096 15.8 0.4 2 23 246 267 246 267 0.97

9 24 0.00023 0.0092 15.9 0.4 1 23 273 296 273 296 0.96

10 24 0.0068 0.26 11.3 0.1 2 23 386 408 386 408 0.96

11 24 0.0002 0.0077 16.1 0.2 2 23 421 443 420 443 0.96

12 24 0.018 0.72 9.9 0.0 2 23 476 497 475 497 0.96

13 24 0.66 26 5.1 0.6 2 23 506 528 505 528 0.94

14 24 2.8e-05 0.0011 18.8 2.2 1 23 585 607 585 607 0.99

15 24 6.2e-05 0.0024 17.7 2.1 1 23 613 635 613 635 0.98

16 24 0.014 0.54 10.3 0.2 3 23 642 663 641 663 0.93

17 24 0.0031 0.12 12.4 2.6 2 23 675 696 675 696 0.97

18 24 0.00094 0.037 14.0 0.3 1 23 702 725 702 725 0.95

19 24 3.2e-06 0.00012 21.8 4.0 1 23 735 757 735 757 0.97

20 24 0.00086 0.033 14.1 0.9 1 23 763 785 763 785 0.97

21 24 0.0036 0.14 12.2 5.9 2 23 794 816 793 816 0.96

22 24 1.1 42 4.4 0.2 1 23 828 850 828 850 0.96

23 24 0.0014 0.053 13.5 0.5 2 23 855 877 854 877 0.91

24 24 7e-05 0.0027 17.6 0.2 1 21 891 911 891 912 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	24	0.2	7.8	6.7	0.2	7	23	41	58	41	58	0.92
2	24	7e-05	0.0027	17.6	0.7	1	23	64	86	64	86	0.96
3	24	0.00015	0.0059	16.5	0.5	3	23	93	114	92	114	0.96
4	24	0.0035	0.14	12.2	4.2	2	23	126	146	125	146	0.97
5	24	3.5e-05	0.0014	18.5	1.8	1	23	153	175	153	175	0.99
6	24	0.026	1	9.5	3.5	1	21	181	201	181	203	0.92
7	24	0.0042	0.16	12.0	5.6	2	23	212	233	211	234	0.95
8	24	0.00025	0.0096	15.8	0.4	2	23	246	267	246	267	0.97
9	24	0.00023	0.0092	15.9	0.4	1	23	273	296	273	296	0.96
10	24	0.0068	0.26	11.3	0.1	2	23	386	408	386	408	0.96
11	24	0.0002	0.0077	16.1	0.2	2	23	421	443	420	443	0.96
12	24	0.018	0.72	9.9	0.0	2	23	476	497	475	497	0.96
13	24	0.66	26	5.1	0.6	2	23	506	528	505	528	0.94
14	24	2.8e-05	0.0011	18.8	2.2	1	23	585	607	585	607	0.99
15	24	6.2e-05	0.0024	17.7	2.1	1	23	613	635	613	635	0.98
16	24	0.014	0.54	10.3	0.2	3	23	642	663	641	663	0.93
17	24	0.0031	0.12	12.4	2.6	2	23	675	696	675	696	0.97
18	24	0.00094	0.037	14.0	0.3	1	23	702	725	702	725	0.95
19	24	3.2e-06	0.00012	21.8	4.0	1	23	735	757	735	757	0.97
20	24	0.00086	0.033	14.1	0.9	1	23	763	785	763	785	0.97
21	24	0.0036	0.14	12.2	5.9	2	23	794	816	793	816	0.96
22	24	1.1	42	4.4	0.2	1	23	828	850	828	850	0.96
23	24	0.0014	0.053	13.5	0.5	2	23	855	877	854	877	0.91
24	24	7e-05	0.0027	17.6	0.2	1	21	891	911	891	912	0.93

Sequence Information

Coding Sequence: ATGGAAATAAAAATTGAGAAAGAGGATCCCGATTACTCATATCAGCCTGAGACATTGTTTGTGAACTGCGATAATGTGAAGGAAAACTATGCGCTTCAGGACATTAAAGAAGAGCCTGTCGACGAGAGCTTTAAGATTGCGTCTCAACTGAAGAAGCATTTGAGCACTACTCACGCCACTGAGAGGAGTTTTGAGTGTGCCTATTGCTCGAAGACGTTCAAGGGAAAGGGAAATCTTCTTGAGCATATCACGTTTCATCTGGAAAAGCCTCGGCCGTGTCCGATTTGCAACAAGATTCTGAAGAATTCTCGTGCAGTGAAGAAACACATGAGAAATCAACACAGAGGCAGTGAAATTGCACTGCGAAAGCCAGTTTCTTGTCACATCTGTGGCAAGATCTACTCAAGTGATCACTATCATCGACACTTGGCGACTCATGTGAAGATTGAGCGGAGTTTTAAGTGTGAAATCTGCCATCGAGAGTTCGGCAAAAGCTGGTTGCTCAAGGATCACATGAGCACTCACAGTGCAGAGAAGCCATTTGCTTGCGATGTCTGCAGTAAGACATTCAGGACGAAAGTAATCCTCACTCGGCATAAAAAGTGTCACGTTCCTCTCACCGAACCGCCCAAGAAATGTCTCTATTGCTCCAAAACTTACAGGCAACATTCCAGTTTCGATCAACACATGATTATTCACCACAGAGGACTTCCTAAGAGATCAAATAAAATTCCCGTTTGCACAGTTTGCAATACGAAATTCAAGAATCTAAAAGAATTGATCGATCACGTGAAGATTCATAAACTGGAGAAACGCTTCGAGTGTGCAACTTGTGGTGCGAAATTTGTCTACAAATCCAAATTGAAATATCATATTGATATGATTCACTTGAATCGAGAGAATGAGACGAAAGAGGAACAAAAGAAATTCACTGTGGTAAACATAAGGAAAGTGAAAGTCTTGACAAGGAGTGAGATTGTTAATATAATTAAGGAAGAACCACCTGATCCTGAGCCACAAGATAACAATGATCAGGGCGGAAGCTCAACTGTGGAGAAGACAATTAAGACGGAGGATTGCGAAAGAAGAGTTGAGAAGAAAGATTGTCTTCGGGCGCTGCTTAGGCGGATTCGGAGTTACTTGGAGAAACCTCGATCGTGTCCAATTTGTCAGGTGGTCGCGAGGAACTCTCGGAGTCTCGAGGATCACGTGAGGATTCGACACAAGGAATGCAGCGCAGCGGGGAAGGAGAGTCAGCTGGAGTGTGCAGAATGTGGCATGAGATTTGAGGAAAAAGATCTGGTGAAGAGACACATGAAGAGGATTCATTTGAAGTCGAAGGGCCGCAGGGAGAAGATATCGAGCAACAACTACTTGACCAATCTGAAGAAGACTCTGCAGAGACAGAGTTCCAAGACGCCGCTAGTGTGCCAAATTTGCCGGGAGGAATTTGCCTACGTCAATTCCCTCGCGGTTCACATCGAGAGTCACGAGTCGCTGGACGACAGAAGGATCGTCTGTCCCTTCTGCTCGTGCATTGTGGGCCAGAATTTCACTTTGCGCCAGCATGTGGCGAAATATCACCCGAAATTTGTGTCCAGCAAGAATTCCGCCCCGAAGACAATGAATATGAATTTCGTGTTTGAGAGAATGGCATTCTTCTGCAACTTGTGCGGATGGATTTCCACCTGCCAATACTtccacgatcgacacatggcgagacacagtaagccggcgaaggcgcgcaaggtttacgagtgcgaaacgtgccactggaagtatgacagaagagacaagctgaggatacacatgttaacgcacggcacggagaagccctatgtctgcgatgtctgcaacaaggcattcCATTCGAGCTTCCTGCTGAAGCGTCACAAATTGATTCACAATCCTGAGCCCCGAAATTGTCTCTATTGCAAGAAGATCTTCAACACTGGCTATGGATTGCAGATGCACCTGGCGAATGTCCACAGAGGTCTGCCTAGGAAGGGTGGTTCCGATGCTTCGTGCACAATTTGCAAGAAACACTTTCAGAGCATGACAGAATTGATGGCGCACACGAAGATACACAAGTTCCAACAGTGCTTCATATGCGCATTGTGTGGCGTAAAAGTACGCAAGAAATATGCTCTGCAGCGACACATGGAGAATTTCCATATGCATAAGAAGGATTCTGAGGACAAGCACAAGTGCGATGTTTGCCAGAAGACCTTCAACTACAAATACAATCTGCAGAGACATTTGCAAGCGCACAGCAAAACCAAACCGTTTCCCTGCAAAGTGTGCAACAGAAAGTTCAAGTTCATCGATTCGGTGAAGAGTCACATGGAGGAGCATGAAGTGTTGAAGGGAAGTGCCAAGAAGTGCTTCTACTGCACGAAGTGTTACGACGACAAGAGCACAATGCGGAAGCACGTGAGACTGAAGCATCCTGGATTGCCGCTCAACACCGCCGGACCGCCGTTCAGGTGTGCAATTTGCCGCGAAGACTATCTGACGATGAACGATCTGAAGGAGCACGTGAAGGAACACAGGAAATTCCTCACGTGCGGCATTTGCAAGCAGACCTTCAAGGCCAGATACAACCTGAAACTCCACGTTGGCTCTCAACACAGAGACTCCAATTTGCCGAAAGTGATTCTGGAGAAATGCTTCGAGTGTTCAATTTGTGGGAAGAAATTCGACCGAAGGTATCCATTGAAGGTGCACGCAATGAAGTGCGTGGCGAAGAGACGACAATCAGAGAGACTGAAGAAGCGCAAGAAGAGATGA
Protein Sequence: MEIKIEKEDPDYSYQPETLFVNCDNVKENYALQDIKEEPVDESFKIASQLKKHLSTTHATERSFECAYCSKTFKGKGNLLEHITFHLEKPRPCPICNKILKNSRAVKKHMRNQHRGSEIALRKPVSCHICGKIYSSDHYHRHLATHVKIERSFKCEICHREFGKSWLLKDHMSTHSAEKPFACDVCSKTFRTKVILTRHKKCHVPLTEPPKKCLYCSKTYRQHSSFDQHMIIHHRGLPKRSNKIPVCTVCNTKFKNLKELIDHVKIHKLEKRFECATCGAKFVYKSKLKYHIDMIHLNRENETKEEQKKFTVVNIRKVKVLTRSEIVNIIKEEPPDPEPQDNNDQGGSSTVEKTIKTEDCERRVEKKDCLRALLRRIRSYLEKPRSCPICQVVARNSRSLEDHVRIRHKECSAAGKESQLECAECGMRFEEKDLVKRHMKRIHLKSKGRREKISSNNYLTNLKKTLQRQSSKTPLVCQICREEFAYVNSLAVHIESHESLDDRRIVCPFCSCIVGQNFTLRQHVAKYHPKFVSSKNSAPKTMNMNFVFERMAFFCNLCGWISTCQYFHDRHMARHSKPAKARKVYECETCHWKYDRRDKLRIHMLTHGTEKPYVCDVCNKAFHSSFLLKRHKLIHNPEPRNCLYCKKIFNTGYGLQMHLANVHRGLPRKGGSDASCTICKKHFQSMTELMAHTKIHKFQQCFICALCGVKVRKKYALQRHMENFHMHKKDSEDKHKCDVCQKTFNYKYNLQRHLQAHSKTKPFPCKVCNRKFKFIDSVKSHMEEHEVLKGSAKKCFYCTKCYDDKSTMRKHVRLKHPGLPLNTAGPPFRCAICREDYLTMNDLKEHVKEHRKFLTCGICKQTFKARYNLKLHVGSQHRDSNLPKVILEKCFECSICGKKFDRRYPLKVHAMKCVAKRRQSERLKKRKKR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01191674;
90% Identity: iTF_01191674;
80% Identity: iTF_01191674;