Parg002182.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Phlebotomus argentipes
Gene Symbol
-
Assembly
GCA_947086385.1
Location
CAMTYR010000041.1:9048768-9052099[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 7e-06 0.00027 20.7 1.8 1 23 143 165 143 165 0.97
2 18 2.7e-05 0.001 18.9 0.3 1 23 171 193 171 193 0.98
3 18 3.6e-05 0.0014 18.5 2.2 1 23 199 221 199 221 0.98
4 18 9.1e-07 3.6e-05 23.5 2.0 1 23 227 249 227 249 0.97
5 18 0.00024 0.0095 15.9 4.8 1 23 255 277 255 277 0.98
6 18 6.1e-05 0.0024 17.7 5.7 1 23 283 305 283 305 0.97
7 18 5.5e-07 2.2e-05 24.2 4.9 1 23 311 333 311 333 0.98
8 18 8.5e-08 3.3e-06 26.7 2.7 1 23 339 361 339 361 0.98
9 18 6.3e-05 0.0024 17.7 6.7 1 23 367 389 367 389 0.97
10 18 8.4e-05 0.0033 17.3 6.5 1 23 395 417 395 417 0.98
11 18 1.3e-06 5e-05 23.0 4.3 1 23 423 445 423 445 0.98
12 18 5.6e-06 0.00022 21.0 7.6 1 23 451 473 451 473 0.98
13 18 8.4e-05 0.0033 17.3 6.8 1 23 479 501 479 501 0.98
14 18 1.5e-05 0.00057 19.7 7.7 1 23 507 529 507 529 0.98
15 18 4.8e-05 0.0019 18.1 6.3 1 23 535 558 535 558 0.95
16 18 5.4e-05 0.0021 17.9 0.4 1 23 564 586 564 586 0.97
17 18 0.007 0.27 11.3 3.9 1 23 596 618 596 618 0.98
18 18 8.3e-05 0.0032 17.3 1.3 1 23 624 647 624 647 0.96

Sequence Information

Coding Sequence
ATGGACTTCCGGGCTCCGGATGGATCACTACTGAAAATATCTAGTGGATTTCCTGAACCTGACATAGGAAAAGCATTAGGAGTTGAAATGTATAAGGTAAATATCGAGGATCTCAGTCAATTTTTGTCATATCATGAGGTGTTCGGGAAGCTACCCAACGAGGCTGCGCCCACGGCTTCGGGCATCAACATCGCCACGACGGCGGGAACCCTCAACATTGTCAGCAGTAGCAACAATGCAATGCAGCCGCCGCCGCATCCGCCAGTGCCCAACCTCCCTGGCGAGCCGCCGTCCGTCAGCTCGGCCCCGCCGGCCATCGTGACGTCCGTGCCGCCGGTGGACACGAAGATGGAGCCGCCTAGCGTGCTGAACTCCGATCCGTCGCTACCCAACTCGGGCGAGAGTCCAGTGATCGTGCCGCTgtcgcattcgtgcgacatttgcggcaagatgttccccttccgttaccagttgattgtgcacaggcgctaccacaacgagcgcaagccattcacgtgccaggtgtgcggccagggcttctccaacacggcggacctctcgcgccacggaaagtcccacattggcggccccatgttcatgtgcacagtgtgctttcacgtgttcgcgaacgacagcagtctggagcgtcacatgaagcgtcactccacggacaagccattcgcgtgcacaatctgccagaagacgttcgcgcgcaaggagcacctggacaatcacatcaggagtcacacgggtgagacgccgttccggtgtcagtactgtgcgaagaacttcacgcggaaggagcacatggtgaatcacgagaggaagcatacaggggagacgccgcaccgatgtgatatatgcaagaagtcgttcacgcggaaggagcactacgtgaatcactacatgtggcacacgggcgagacgccgcatcagtgccaggtgtgcgggaagaagtacacgcgcaaggagcacctggccaatcacatgcgatcgcacacgaacgagacccccttcaggtgtgagatctgcggcaagagcttcacgcggaaggagcactttaccaatcacatcatgtggcacactggcgagacgcctcatcgctgcgacttctgctcgaagacgttcacgcgaaaggagcacctactgaatcacgtgcgccagcatacgggcgaatcgccgcacaggtgtacgtactgcatgaagtccttcacgaggaaggagcacctcgtcaatcacatcagacaacacactggcgagacgcccttcaagtgcacctactgtacgaaagccttcacgagaaaggatcatctGGTAAATCACGTGAGGCAAcatacgggtgaatctccgcacaagtgctcctactgctccaagagtttcacgaggaaagagcacttgacgaatcatgtGCGCCAacataccggagaatcgcctcatcgctgtacgttttgtatgaagtctttcacgaggaaagaacatctgactaatcacattcgaatacacacgggagactcgccgcatcgatgtgaattctgccagaagacttttacgcgaaaggaacatcttacgaatcacttgagacaacattccagcgaaaatccccattgttgcaatgtgtgcaataaaccgttcaccagaaaggagcacttgattaatcatataagTCGATCTCACACTGGTGAGAGACCCTTTGCATGCAATGAGTGCGGAAAATCGTTTCCACTGAAGGGAAATTTGCTCTTTCATCAGCGTAGTCACAACAAGGGAGCGGCAGCTGAACGCCCATTTCGCTGTGATTTATGCCCTAAGGATTTTATTTGCAAAGGTCATTTGGTGTCACATCGGAGATCTCATTCGGACGAGAAGCCATACGTCTGTATTCACTGCGGGAAGTCATTTGTTGAGAAGGGCAATATGCTGAGGCACATCAAGAAGAACCATCCGCAGGCCGCGCCGGTTGTTCTGGAGCCTCAAGTGATCATATCGCATCAAAAGGCCACGCTGCTGTCGCCCCAGATAAACGCGGCGAGGCCCATCTGTAGCACAACGGAGACGGTGAGCGCACTTCCTGTGACTTCGACGATAACGTCTCACATCCTCCAGCATACGAACTCACAGACTGCACTGAGGTTGCTGCAGAGCAGCGAGCCACCGCCGCCTCCGCCACCCATTCCTGTTCATCCGCCGGAGAATTCGGTGGCGCTGCAAGTGAATGTTCACAATCACAATCCAGTGAATGCTCCTCCGCCGCCACATCCGCAGCTGAAGCCTTAG
Protein Sequence
MDFRAPDGSLLKISSGFPEPDIGKALGVEMYKVNIEDLSQFLSYHEVFGKLPNEAAPTASGINIATTAGTLNIVSSSNNAMQPPPHPPVPNLPGEPPSVSSAPPAIVTSVPPVDTKMEPPSVLNSDPSLPNSGESPVIVPLSHSCDICGKMFPFRYQLIVHRRYHNERKPFTCQVCGQGFSNTADLSRHGKSHIGGPMFMCTVCFHVFANDSSLERHMKRHSTDKPFACTICQKTFARKEHLDNHIRSHTGETPFRCQYCAKNFTRKEHMVNHERKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGETPHQCQVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFTRKEHFTNHIMWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCTYCMKSFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHLVNHVRQHTGESPHKCSYCSKSFTRKEHLTNHVRQHTGESPHRCTFCMKSFTRKEHLTNHIRIHTGDSPHRCEFCQKTFTRKEHLTNHLRQHSSENPHCCNVCNKPFTRKEHLINHISRSHTGERPFACNECGKSFPLKGNLLFHQRSHNKGAAAERPFRCDLCPKDFICKGHLVSHRRSHSDEKPYVCIHCGKSFVEKGNMLRHIKKNHPQAAPVVLEPQVIISHQKATLLSPQINAARPICSTTETVSALPVTSTITSHILQHTNSQTALRLLQSSEPPPPPPPIPVHPPENSVALQVNVHNHNPVNAPPPPHPQLKP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01192011;
90% Identity
iTF_01191360;
80% Identity
iTF_01191360;