Parg008830.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Phlebotomus argentipes
Gene Symbol
Hr39
Assembly
GCA_947086385.1
Location
CAMTYR010000037.1:15042039-15044610[+]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 0.032 2e+02 0.6 1.5 32 119 197 250 117 338 0.57
2 4 6.5e-08 0.00041 19.4 0.0 1 27 408 434 408 442 0.88
3 4 0.0055 34 3.1 0.0 97 138 465 507 433 517 0.71
4 4 2.3e-77 1.5e-73 248.1 0.3 183 408 503 718 488 718 0.94

Sequence Information

Coding Sequence
ATGGCAAGTGCCGGAGAGTGCGGAAAAGGGTCCAACATCAGTGTGACCAACATCAATTGCGATCAGGGTGGAATGCAGACGCCTGCCATTGAGGCCACAGTGCAGGGTAACGGATCTGGAGGGGCTCTTGCAGCTCGCGCCACGACGCCGAATCACTTCTACGGCGGCAGCGGCAGCATTAGGATCTCCGTGCCGAAAATGGAGGAGTCCGATGAGTCGGACAGTGAACTGCTGACGATCGAGGAGAGCGCCAAGGTGAACATGAGGACGAAGGGCGACGGAACGGCTGCCAAAACCGCTCCGCGGCCCATGTCATGGGAGGGTGAGTTGTCTGAACATGAAGACGTTATGGATGTGGACAATGTGGCGAGCAATGGGACCGCGATTGCCGCGACGTTCGGCGATCCGGTGATAAAGGTGGAGCAGCGCGATATGGATGCGAAGGAAGAGAAAGTGACAGATGAGGCGATTTCCCTGATAGCTAAGGCCTCCAGTGAGTCGAGCAACGTCCCAGTGGATGCCACCGGAAAGCACTTCATGCAGAACGACGTGGTGAACTTGAAAGTGGAGTCCAACATGCCGGAGTACAATTCATCCGTGCAGGCGCCACTACTTGTGCGCTCCAAGACAACTCTCCTGCCAGCCAATCCGAGCCCAGACTCTGCAATCCACTCCGTCTACACGCACAGCTCGCCGAGTCAGTCGCCGCTCACGTCCCGCCACAACATTTACACACCCTCGCTGAGCCGGAACAACAGCGATGCCTCGCACAGCAGCTGCTACTCGTACAGTTCGGAGTTCAGCCCCACGCACTCCCCAATTCAGGGACGCCACAGCATGTACGGCGCCATAAATGGCTCTCCTCTGCACCACAGCGTCCTGTACAGGCCTACAGTGTATCCAGTGGATGCGGAGTCTCCCGCCGCAAGGGCGTGCTTTGACGACTCGGCAGCGCTCGAGGGAGAGGCTCTGCCGTCGGCGGGCATCTCCAGACAACAGCTCATCAACAGCCCgtgcccgatttgcggagacaagatctcgggcttccactatggcatcttctcatgcgagtcgtgcaaaggattcttcaagagaaccgtccagaataggaagaactacgtttgcgtccgaggatctgcgtgtccggtgaccattgccacgaggaaaaagtgtccggcatgccgctttgagaagtgccttcaacgtgggatgaagctcgaagCAATTCGTGAGGACAGAACCCGCGGAGGTAGATCGACGTATCAGTGCTCATTCACGTTGCCTGGATCAATGCTGTCGCCCTCTGTGATGTCAGAGTCGTCGGGATGCCATCAGAACTATCGCATGACTGTGCCGCCGATGAAGGTTGAGGTGGGCGAGAGTGCGGGCGGCTCCAAGCCACGCATTCCGACGCTTCTCCAGGAGATTATGGATGTTGAGCATCTCTGGCAGTACAACGAATCGGAGCTGCTGAGACTCAACCAACCGGCGCCGCCGGTGACGAATGGGACACAGGCAACGAATCCTCTGCTGGCCAGCGCTGGACTATCGCAAGGGGACAATTCCAATCCAGACTTAATCGCAAATCTGTGCAATATTGCCGATCATCGGCTCTACAAGATTGTCAAGTGGTGCAAGAGTTTACCGCTCTTCAAGACCATCTCGATTGACGATCAAATTTGTCTCCTGATTAACTCGTGGTGTGAACTTCTGCTCTTCTCCTGCTGCTTCCGATCCATTTCCACACCCGGAGAGATTCGAATATCCCAGGGAAAGTCTATAACATTGGCTCAGTCGCGATCTAGTGGATTGCAAGCTTGTGTGGAGAGAATGCTCAATTTGACTGATCACTTGAGACGCCTTCGCGTCGATCGCTATGAATATGTTGCGATGAAAGTAATTGTATTGCTTCAATCAGACACTTCGGAGTTGAAGGAACCAGAAAAGGTGCGCACAAGTCAGGAGAAGGCTTTGCAGGCACTTCAAGCTTACACTTTGGCTCACTATCCAGAATCACCTGCCAAATTCGGAGAGTTGCTTCTGCGAATTCCTGAGTTGCAACGAACTTGCCAGGTCGGTAAAGAGATGCTGACGATCAAGTCAAAGGAAGGAGACGAATTTGATCTGCTTATGGAGCTCCTGAGAGGTGAACATTGA
Protein Sequence
MASAGECGKGSNISVTNINCDQGGMQTPAIEATVQGNGSGGALAARATTPNHFYGGSGSIRISVPKMEESDESDSELLTIEESAKVNMRTKGDGTAAKTAPRPMSWEGELSEHEDVMDVDNVASNGTAIAATFGDPVIKVEQRDMDAKEEKVTDEAISLIAKASSESSNVPVDATGKHFMQNDVVNLKVESNMPEYNSSVQAPLLVRSKTTLLPANPSPDSAIHSVYTHSSPSQSPLTSRHNIYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQGRHSMYGAINGSPLHHSVLYRPTVYPVDAESPAARACFDDSAALEGEALPSAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGSACPVTIATRKKCPACRFEKCLQRGMKLEAIREDRTRGGRSTYQCSFTLPGSMLSPSVMSESSGCHQNYRMTVPPMKVEVGESAGGSKPRIPTLLQEIMDVEHLWQYNESELLRLNQPAPPVTNGTQATNPLLASAGLSQGDNSNPDLIANLCNIADHRLYKIVKWCKSLPLFKTISIDDQICLLINSWCELLLFSCCFRSISTPGEIRISQGKSITLAQSRSSGLQACVERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTSELKEPEKVRTSQEKALQALQAYTLAHYPESPAKFGELLLRIPELQRTCQVGKEMLTIKSKEGDEFDLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01191234;
90% Identity
iTF_01191234;
80% Identity
iTF_01191234;