Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.46 9.3e+03 -0.7 0.3 23 46 67 90 62 98 0.80

2 9 0.012 2.4e+02 4.4 0.8 22 47 94 119 86 124 0.85

3 9 0.034 6.8e+02 2.9 0.2 21 44 121 144 119 149 0.90

4 9 0.00023 4.6 9.9 0.1 21 50 149 178 145 180 0.86

5 9 0.00013 2.6 10.6 0.1 21 52 177 208 175 210 0.87

6 9 0.074 1.5e+03 1.8 0.0 21 45 205 229 203 232 0.89

7 9 3e-05 0.6 12.7 0.2 21 50 233 262 229 264 0.87

8 9 0.0027 55 6.4 0.1 21 52 261 291 258 292 0.87

9 9 0.0038 76 5.9 0.1 21 43 288 310 285 315 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.46	9.3e+03	-0.7	0.3	23	46	67	90	62	98	0.80
2	9	0.012	2.4e+02	4.4	0.8	22	47	94	119	86	124	0.85
3	9	0.034	6.8e+02	2.9	0.2	21	44	121	144	119	149	0.90
4	9	0.00023	4.6	9.9	0.1	21	50	149	178	145	180	0.86
5	9	0.00013	2.6	10.6	0.1	21	52	177	208	175	210	0.87
6	9	0.074	1.5e+03	1.8	0.0	21	45	205	229	203	232	0.89
7	9	3e-05	0.6	12.7	0.2	21	50	233	262	229	264	0.87
8	9	0.0027	55	6.4	0.1	21	52	261	291	258	292	0.87
9	9	0.0038	76	5.9	0.1	21	43	288	310	285	315	0.90

Coding Sequence: ATGCTTATGTCCTCACGCTCGGCGGACCCATTACGCATGCATCCACTCTTCCACATCCACTTTTGTAGCGATTTTATGAATGGGTACACCTTATGGAACTCACGATCTACTAGGCATGGCGCTATACTAACCACACTAACTTTAAAATACAAAGACAATGCTTTTATAAGCGCGCGAGACAAGATCAACGCCGACAGCCGACCGCACAGATGTGACGAATGCGGCAAACGATTCCGTCAACAAAATCATCTCGCTCAGCACCAGCGAATCCACACCAACGACAGACCGTACGTGTGCCGCCTTTGTGGACGCTACTTTAGACAACAATCCACTCTGAACCAACACCTATTGATCCACACGGGCGAGAAGCCGTACGAGTGCGACTACTGCGAACGCACCTTTAGACAGCGCGCCATTTTGAACCAACATCTATTGACTCACACGGGCGAGAAGCCGTACGAGTGCGACTACTGCGAACGCACCTTTAGACAGCGCGCCAATTTGAACAAACATCTATTGATCCATAAGGGCGAGAAGCCGTACGAGTGCGACTACTGCAAACGCACCTTTAGACAGCGCGCCAATTTGAACAAACATCTATTGATCCACAAGGGCGAGAAGCCGTACGAGTGCGACAACTGCGAAGGCACCTTTAGACATCGGGCCAGTTTGAACAAACATCTATTGATCCACAAGGGCGAGAAGCCGTACGAGTGCGACTACTGCAAACGCACCTTTAGACAGCGCGCCAATTTGAACAGACATCTATTGATCCACAAGGGCGAGAAGCCGTACGAGTGCGACAACTGCGAACGCACCTTTAGACAGCGCACCAGTTTGAACAAACATCTACTGATCCATTCGAAGAAGCCGAACAATTGTCCGGAGTGCGGGAAACACTTTCGGCAGAAGTCGCAGCTCGATAAACACGCTCGAGCACATCAAAGTGATGTGTCCGAAGATGAATCATCTGAGGACAAAACCTAG
Protein Sequence: MLMSSRSADPLRMHPLFHIHFCSDFMNGYTLWNSRSTRHGAILTTLTLKYKDNAFISARDKINADSRPHRCDECGKRFRQQNHLAQHQRIHTNDRPYVCRLCGRYFRQQSTLNQHLLIHTGEKPYECDYCERTFRQRAILNQHLLTHTGEKPYECDYCERTFRQRANLNKHLLIHKGEKPYECDYCKRTFRQRANLNKHLLIHKGEKPYECDNCEGTFRHRASLNKHLLIHKGEKPYECDYCKRTFRQRANLNRHLLIHKGEKPYECDNCERTFRQRTSLNKHLLIHSKKPNNCPECGKHFRQKSQLDKHARAHQSDVSEDESSEDKT

Sequence clustering based on sequence similarity using MMseqs2