Basic Information

Insect: Philonthus cognatus
Gene Symbol: -
Assembly: GCA_932526485.1
Location: CAKOBG010000203.1:196469-204646[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.00015 0.031 17.0 2.4 1 23 431 453 431 453 0.97

2 18 9.2e-05 0.019 17.7 1.8 1 20 459 478 459 481 0.94

3 18 0.00013 0.027 17.2 1.0 1 23 487 509 487 509 0.98

4 18 5.7e-06 0.0012 21.5 4.4 1 21 515 535 515 537 0.95

5 18 4.5e-05 0.0094 18.6 4.6 1 23 543 565 543 565 0.99

6 18 4.5e-05 0.0094 18.6 5.3 1 23 571 593 571 593 0.97

7 18 4.6e-07 9.5e-05 24.9 5.0 1 23 599 621 599 621 0.98

8 18 1.7e-07 3.5e-05 26.3 2.7 1 23 627 649 627 649 0.98

9 18 0.00012 0.026 17.3 6.7 1 23 655 677 655 677 0.97

10 18 2e-05 0.0042 19.7 5.5 1 23 683 705 683 705 0.97

11 18 5.9e-07 0.00012 24.6 2.4 1 23 711 733 711 733 0.98

12 18 1.1e-05 0.0023 20.5 7.9 1 23 739 761 739 761 0.98

13 18 4.8e-05 0.01 18.6 9.1 1 23 767 789 767 789 0.98

14 18 1.5e-05 0.0032 20.1 7.7 1 23 795 817 795 817 0.98

15 18 9.3e-05 0.019 17.6 7.6 1 23 823 845 823 845 0.97

16 18 0.00026 0.054 16.2 0.5 1 23 851 873 851 873 0.97

17 18 0.044 9.2 9.2 5.1 1 23 883 905 883 905 0.98

18 18 1.2e-06 0.00025 23.6 0.9 1 23 911 933 911 933 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.00015	0.031	17.0	2.4	1	23	431	453	431	453	0.97
2	18	9.2e-05	0.019	17.7	1.8	1	20	459	478	459	481	0.94
3	18	0.00013	0.027	17.2	1.0	1	23	487	509	487	509	0.98
4	18	5.7e-06	0.0012	21.5	4.4	1	21	515	535	515	537	0.95
5	18	4.5e-05	0.0094	18.6	4.6	1	23	543	565	543	565	0.99
6	18	4.5e-05	0.0094	18.6	5.3	1	23	571	593	571	593	0.97
7	18	4.6e-07	9.5e-05	24.9	5.0	1	23	599	621	599	621	0.98
8	18	1.7e-07	3.5e-05	26.3	2.7	1	23	627	649	627	649	0.98
9	18	0.00012	0.026	17.3	6.7	1	23	655	677	655	677	0.97
10	18	2e-05	0.0042	19.7	5.5	1	23	683	705	683	705	0.97
11	18	5.9e-07	0.00012	24.6	2.4	1	23	711	733	711	733	0.98
12	18	1.1e-05	0.0023	20.5	7.9	1	23	739	761	739	761	0.98
13	18	4.8e-05	0.01	18.6	9.1	1	23	767	789	767	789	0.98
14	18	1.5e-05	0.0032	20.1	7.7	1	23	795	817	795	817	0.98
15	18	9.3e-05	0.019	17.6	7.6	1	23	823	845	823	845	0.97
16	18	0.00026	0.054	16.2	0.5	1	23	851	873	851	873	0.97
17	18	0.044	9.2	9.2	5.1	1	23	883	905	883	905	0.98
18	18	1.2e-06	0.00025	23.6	0.9	1	23	911	933	911	933	0.96

Sequence Information

Coding Sequence: ATGGGCAAAAAGTTGGTGGAGAGAGGCAGTATTCTGTTCCCGATTTTTTTGAGAAATTTCGAAATCTACTTCCCAATCTTGACGTTGATGATAGCTGTTGTCGATGTACTCTTCGGCGTGCTGTACAAGTCTTTCGTGACACTGGAAGTGTTGAATGTGCAGAGGCCTCCGACTTCCACGAGCGCCGCATCCGCCACCGATCTGCGAGTGAACACCACGGCGCTGAACGCGGTTACCCTGAGCAGCGTCGCAAAGTACTGGGTTCTGACAAATTTACTCCCCGGGCCCATACCTCAAGTGTCCGTTTACGGGCTGCCTGGAACAGCTAGACCATCCGACGAATCACAAGGAAAAGCCCCACAGGATTCGATGTCAGTCCCACAGCACGGGGGTTTGATACCCTCCGAGAACCTCATACTCTCACACAACTCTCAAATCCCACCTGTCTCGATGCCATCAAATATATCGATACCGACGTCTAGTAGCATGCACATCGACTCGCAGCAACAACAACAAAACAACCATCACCAACAACAGCAACAACAACAAAACGAGAACCAAAATCAATCGATGTTATCGCAACAACAACAGCAGCAGCAACAAAACCATTTGCAGCAACAACAAAATCAACAGAATCAAAACATGGTCCAAGTGCAAGTTCAGGATAATCTGGTTTCGGTGATCGAGGATAACAACAAGGATCAATTAAGAGCGCAGTTGCACATGAATAACGAGAACCAGCATCAGCAGCACCAGACGTTGACGGTGCAGCAGTTGCAGCATCTGCAAGTGCAGCAGGTGTTGGACAATGTGGTGCGGATAGAGAACAGCGAGCAGCAGCAGAACAGCGGAGAGAACAACATGGGTGAGGGCATGCAGATCAAAGATGAGAAGGTCTTGCAGAACTGCACCAAGTTGTTGAGCGCGCAGTTCGGGTTGCAGGATGTTAAAGCAAATTTGATGGACGTCAGGATCGTTGACGGAAACATCGCTAAAATTTCAACAGGCATGCAAGATCAAGAACTAGCAAAGACGATAGGAGTCGAGATGGTGCAGAACATGTACAAGGTGAACGTGGACGATCTTAACCAGCTGCTGGCATACCACGAAGTGTTCGGCAAGCTACAGGGAGAGATAACCACTGGAACGGGGAATTTGGTGCAAACGACCAACGCCGGGGGGGTCAACTTGCAGGGAAATAATTTAGCGGTGGTTCCGAAGGTTTTGGAGAACGAGAGTGAAGCGTCCACTAGCGGGATGAGCAGTCCTCCCCCTATGATAGCGGGTACTCATGTAtgtgatctctgtggaaaaatgtttcaattccgctaccaactaatcgttcaccgtcgataccacacggagcggaaaccgttcacctgccaggtgtgcggcaaggcgttcacgaacgcaacagaactaagccgtcacggcaagtgccacttaggcggcagcatgtttacctgcaccgtctgcttccacgtgtttgcaaacgcagccagcttggagaggcacgcgaagcgccactcgacggacaagccatacacgtgtacgatctgcggcaagtcgttcgcgcggaaggagcacctggagaaccacaccaggtgtcacacgggggagacgccgtacaggtgtcagtactgtgccaagacttttacgaggaaggagcacatggtgaaccacgtcaggaagcacacgggggagacgccgcacaggtgcgatatttgtaagaagtcgttcacgaggaaggagcattttatgaatcacgtgatgtggcatacaggcgaaacaccgcatcagtgtacgatatgtgggaagaagtatactagaaaggagcatcttgctaatcatatgaggtcgcatacgAATGATACTCCTTTTAGgtgtgaaatatgtggtaaatcgttcacgaggaaggaacatttcacgaaccacataatgtggcacacgggagagacgccgcaccgctgcgacttctgctcgaagaccttcacccgcaaagagcacctgctgaaccacgtacggcagcacacaggcgagtcaccacaccgctgcgcctattgctccaagtcgttcacccgtaaagagcacctgataaaccacgtgcggcagcacacaggcgagaccccgttccgctgcgactactgcccgaaggcgttcacccgcaaggaccacctcgtgaaccatgtcaggcagcacactggagagtccccacataaatgcacgtactgtacgaagagctttacgaggaaggagcatttaacgaatcatgtgaggcagcatacgggcgagtcgccccatcgatgccatttctgctcgaagagcttcacgaggaaggagcacttaacgaaccacgtgcggatacacacaggcgagtcaccgcaccggtgcgagttctgcaataagaccttcacaaggaaggagcacctgacgaaccacttgcggcagcacacgggagaaacgccgcactgctgcacgctgtgttcgaaaccgttcacgaggaaggagcatctggtgaaccacatgcgctcgcacacaggtgagagaccgttcacatgcactgagtgcgggaagagcttcccgctcaagggaaatctgctgtttcacgcacgatcgcacaacaagggagccaacgccgagcggccgttccggtgcgacctctgtgacaaggacttcatgtgcaaggggcatctggtgtcgcaccggaggtcgcacagcggggagaagcctcacgcctgcccggactgcgggaagACGTTCGTTGAAAAGGGAAACATGTTACGGCATTTACGGAAACACGGTACAGGCACCCTGTCCGGTCCTGCCCTTCCAGGAATCCCTGCCGTCAATCCTGGCCAGCCGACCTCATCGTCAGCAGCTCCTCAGACCAGCAGCGTCAACGTGCAATTACCACCGCAGGTCTCACAAGCAGCATCGATTGCCAGCCCGGCCATGAACATGCACCCCCCACCCACGCACCCCATCGTCGTACCCACAGCCAACGGCAATGTCCTCGCCACATATTAA
Protein Sequence: MGKKLVERGSILFPIFLRNFEIYFPILTLMIAVVDVLFGVLYKSFVTLEVLNVQRPPTSTSAASATDLRVNTTALNAVTLSSVAKYWVLTNLLPGPIPQVSVYGLPGTARPSDESQGKAPQDSMSVPQHGGLIPSENLILSHNSQIPPVSMPSNISIPTSSSMHIDSQQQQQNNHHQQQQQQQNENQNQSMLSQQQQQQQQNHLQQQQNQQNQNMVQVQVQDNLVSVIEDNNKDQLRAQLHMNNENQHQQHQTLTVQQLQHLQVQQVLDNVVRIENSEQQQNSGENNMGEGMQIKDEKVLQNCTKLLSAQFGLQDVKANLMDVRIVDGNIAKISTGMQDQELAKTIGVEMVQNMYKVNVDDLNQLLAYHEVFGKLQGEITTGTGNLVQTTNAGGVNLQGNNLAVVPKVLENESEASTSGMSSPPPMIAGTHVCDLCGKMFQFRYQLIVHRRYHTERKPFTCQVCGKAFTNATELSRHGKCHLGGSMFTCTVCFHVFANAASLERHAKRHSTDKPYTCTICGKSFARKEHLENHTRCHTGETPYRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHFMNHVMWHTGETPHQCTICGKKYTRKEHLANHMRSHTNDTPFRCEICGKSFTRKEHFTNHIMWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCAYCSKSFTRKEHLINHVRQHTGETPFRCDYCPKAFTRKDHLVNHVRQHTGESPHKCTYCTKSFTRKEHLTNHVRQHTGESPHRCHFCSKSFTRKEHLTNHVRIHTGESPHRCEFCNKTFTRKEHLTNHLRQHTGETPHCCTLCSKPFTRKEHLVNHMRSHTGERPFTCTECGKSFPLKGNLLFHARSHNKGANAERPFRCDLCDKDFMCKGHLVSHRRSHSGEKPHACPDCGKTFVEKGNMLRHLRKHGTGTLSGPALPGIPAVNPGQPTSSSAAPQTSSVNVQLPPQVSQAASIASPAMNMHPPPTHPIVVPTANGNVLATY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01096809;
90% Identity: iTF_01186416;
80% Identity: -