Palb016975.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Philonicus albiceps
Gene Symbol
BTBD3
Assembly
GCA_963969385.1
Location
OZ017774.1:3271578-3274243[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 1.1e-24 4.6e-22 79.1 0.0 5 106 22 125 20 129 0.92
2 3 0.99 4.3e+02 1.9 0.1 81 109 132 160 127 161 0.84
3 3 1.2 5e+02 1.7 0.0 69 102 370 403 359 408 0.91

Sequence Information

Coding Sequence
ATGGAAGGCTCAATAGATTGGCAGAATGTTTGCCGTGATTTGAAGTCACGCGGCCTGTACCTTCTCGAGACGGAAAAATGGGCAGACTGTAGATTTCTTGTGGGCACCGAGCCCAACCAGCAGGTGCTCTCCGGGCACAAGTTAATCCTTGCAATGGCATCGCCGGTATTCGAGCGAATGTTCTACGGAAATGTCCCGGAGAAGACTGATCCCATCCAGATTCCGGATGTCCAACCGGACGCCTTCAGGGCAATGATGGAATACATCTACTCGGATAAGATTAACATTAGCTCCTTCGACAAGGCTTGTGAGCTGTGCTACGTGGCCAAGAAGTACCTCCTTCCTCACGTCGTGGAGCAGTGCACAAAGTACTTGTGGTCGGATCTTAGCCCCAAAAATGCGTGCCGCGCTTACGAGTTTGCCAAGCTGTTTGAGGAGCCCCAGCTAATGCAGCGGTGTATCCAGataatttgTACTAAAACACGAGAAGTTCTTGCTGATCCCACATTCATGGAAATTGAACTTACaactcttttaattattttcgacCAAGATCAGCTAAATATCGACTCTGAGTTGGATCTTTTCAACGCTTTAAACAAGTACGCCTATGAGCGGGGATACATTTCGAAAAAGTGTGATTCCACTCCGGAATCGCATGAAGCATCCATGGAGCCACAACTTGATGTCGAGAGTATGCAGGAGGCGAGTACTAGCCGAGAAACTAAGGAGCACTCCCCAGGTGAAGGTACATCAAATTGTGACGAAAGTCAAGATACAGAGGAGAAGTATTTAGACGATTTGCTAATTAAAGAGgctgttaaaaaaattcgctTCTTAACTTTAACTCCGCAACAATTTGCTGAAGGTCCAGCTCGCTCAAGGCTTCTGACACAAACAGAAgccctaaatattttaataaacatatcGAGTCCATCGATAAACGATTGCCCAATGCCTGAAGGTTTTTGCAGTAGcagaaataaaaggaattgttTCGCCCGGTGCGAGGAGCAGGGTCCTTCGGGAAGTTTTTCTAAGCACAACGATAACGTTCCATTGGAGTATGGATTCTCTCCGCCAACTCCTCCGGTAGTTTTAAGCGTTAGCTACAGCTATCAACATCCGATTCAGATCCCGGAACCAGACATATCCAATGCCATGGAGACGAGGAAGTTCTACTGTGTTCGGACAATTCGCCAGCAGATCGACTACAGGAATACTAGCGTTACAGATTGTGGTCTAACTTTCCACACGAATGCGAACATCTTAATTACAGGTGTCCAAGTACCGACTCAGGTCCTTTGTGGTGAACTTATGAACTCAGCTGGTTTTACTGAAAgatattcagaaattttatacgCTCACTTGTTGGACGCTCAAGGGTCAAGATTGACCTACACTCATTGCACGTCGCGAGTGCGATACGACTCTTTGCTCGAGATCTCTTTTGATCGTCCTGTATTTATAATCCGAAATAAGATTTATAAGATCGGAGTGGTTTTTAATAAGGTCGGCTGGTACCCAATGTACACTTGCTACGCGGAGGTGACTTGTGACAATGTTCACTTTACATTCAATGTGGGTGCCCCGCATGATTCTCTTCGTGACGGCCTCATTAGAGCGATTGTCTTTACTCATCCGTATGCAGCTCCAGGTCCGCATAGTAATGCTATGGTAGAAATGTAA
Protein Sequence
MEGSIDWQNVCRDLKSRGLYLLETEKWADCRFLVGTEPNQQVLSGHKLILAMASPVFERMFYGNVPEKTDPIQIPDVQPDAFRAMMEYIYSDKINISSFDKACELCYVAKKYLLPHVVEQCTKYLWSDLSPKNACRAYEFAKLFEEPQLMQRCIQIICTKTREVLADPTFMEIELTTLLIIFDQDQLNIDSELDLFNALNKYAYERGYISKKCDSTPESHEASMEPQLDVESMQEASTSRETKEHSPGEGTSNCDESQDTEEKYLDDLLIKEAVKKIRFLTLTPQQFAEGPARSRLLTQTEALNILINISSPSINDCPMPEGFCSSRNKRNCFARCEEQGPSGSFSKHNDNVPLEYGFSPPTPPVVLSVSYSYQHPIQIPEPDISNAMETRKFYCVRTIRQQIDYRNTSVTDCGLTFHTNANILITGVQVPTQVLCGELMNSAGFTERYSEILYAHLLDAQGSRLTYTHCTSRVRYDSLLEISFDRPVFIIRNKIYKIGVVFNKVGWYPMYTCYAEVTCDNVHFTFNVGAPHDSLRDGLIRAIVFTHPYAAPGPHSNAMVEM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00455088;
90% Identity
iTF_00936675; iTF_00717905; iTF_01461276; iTF_00937406; iTF_00628480; iTF_00628483; iTF_00628479; iTF_01256501; iTF_01049785;
80% Identity
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