Pgno001448.1
Basic Information
- Insect
- Pheosia gnoma
- Gene Symbol
- ZFX
- Assembly
- GCA_905404115.1
- Location
- FR989904.1:1337868-1345736[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 2.1 1.2e+02 3.5 0.4 2 23 6 27 5 27 0.96 2 13 1.5 87 3.9 0.1 1 23 1027 1050 1027 1050 0.92 3 13 1.6e-05 0.00091 19.6 1.7 2 23 1150 1171 1149 1171 0.97 4 13 0.00058 0.034 14.7 2.3 1 23 1177 1199 1177 1199 0.98 5 13 0.0075 0.43 11.2 2.5 2 23 1206 1227 1205 1228 0.95 6 13 1.2 71 4.2 1.0 5 23 1241 1259 1240 1259 0.96 7 13 0.018 1 10.0 1.1 3 23 1266 1287 1265 1287 0.96 8 13 0.02 1.1 9.8 0.1 2 23 1304 1324 1303 1324 0.96 9 13 0.00016 0.0092 16.4 2.7 1 20 1330 1349 1330 1352 0.91 10 13 0.00018 0.01 16.3 0.2 1 23 1360 1382 1360 1382 0.98 11 13 0.0053 0.3 11.7 7.2 1 23 1388 1410 1388 1410 0.98 12 13 6.2e-06 0.00035 20.9 1.3 1 23 1416 1440 1416 1440 0.98 13 13 0.00097 0.056 14.0 5.1 1 23 1446 1468 1446 1469 0.95
Sequence Information
- Coding Sequence
- ATGGATCAGCTCGTGCAGTGCCCCGTGTGCACGCTATTCCTCCACAATGGGATGACCCTTGAGTCACATCTAGATACCCATCCCAAAGACCAAGTGATTAAGGCACTGTGCAGTCTGACAACCAAGGGATCCAACTATGGAAGCAGGACTTCCACGCCCCTCCATTCGGAGAGATCGTACAGGAGCAGGTCACGGACACCTGCTACCGAGGATAGTGGGCGATGGAATGGTTCCCATCGCAGCACAGAACCGGATCGCTACTGGCGTCGAACACCAAGTAGGACTCCTAAGACAAATCCTATTTCAAGTGTATCAAGAAATAGCACTCCTGATATCAGAATAAATGAAATGAACTTTGAAAGTGGTTCCATAAACAGCGCAGGGACGCACACTCCATTTGTGATGAAGGCTGATAAAATCCAGCAAACCTACCAGCCCCCACCAGTAACAGATTTTGATCCGCAATATGTGTACTACCCGGATCAGCAGGAGGACAGGGAGATCAAGTATTCCCGGAGTGCCGAATACAATGCAATGGACAGCACTAACAATGTGTTCACATATAACATGCCAACCATAGGGACCGGTGTGAAGTTGTTACCAGCAGTGCCCAGAAGGACTAATGATATTGTTAAAATTTTGCCAAAACAAAACAATATACTACTGAAAACTAACATGGGTGGGGTGCAATACATAAGCCCTGCAGTAAAACCCATGCATGTTGTTGTGCCTACAGCCCCAACATTCCTTCAAAAGAATGTCCAGAACAATATGATTGTGACAAGTAACATACCAAATGCACAGGTTCAGATTGAGACAAAATCAATTGCTCCTTCTTTAACAACCAATTTGAACCAGATGACCTCGAACACATTTACTCCAGGAACCACAGTTGTCACACAGAACTCACAAATTATCTACCGCGAGATGGTTCATAATATAGACGGTAAGCCCTTTATAACTAGCATGCCGACTGTACTTAGTGGTCATGACAATGTTACTAATGTTGCTCAAGCCAGTTCCATGTACCAAAATGTGATGGTTGTGGACCAATTTGGCAATACTTCATGTATGTACACAACACCTCAACAGATTCTTCCTAAATCTTGTACCACATCAATATACAATAACAATGGGCCACTTGTTCCTGGTATCCATATGGAAAAACCTGTTGCAAACTTGAATGATCCCAAAACTCTTATAATTGAAGTAGGTCCTATGTTGCCAGCACATGACCATGCTTCCAGTTCCTCCTGTGAAGCATCTGTCTCCAGCATTCGACAGGCAGAAACTAGTACGACTGAGAAGCTTGAGAGACCTACAAATGAGGTTGAAATGAGAAATGACACACCTGGTGCTAGTAAAGGTTTAAAGATCCTCAGTAACATTAAAGTAGAAGTTCCTGTGCAACATCACAAGAACATGGTGAATACCATCATGGATTTAACCGGGCCTAGTGAGACAGATTATTCTGTACGTCCAGCATCACCTGATAAGATTTTGCCTGACCTAGATGATAATAATCAAACAGAGTCTGAGAAGATTCTGCCTGATTATGATGATAAAACCCAAATGATGGCCAATCCTGAGAGAATCCTGCCTGACATTGATGATAACAATCAGATTATAATGGATGAGTCCACGCAGCCCTCTATGTCGAGCGCCGATAGCATAGTTTCCCACTCATTTTCTGTGATAAAAAATGTTGGTAATCCTCCTTCTTATAAAGACTTGAGCAAGAACTCTGATAGTAAAATGGACGCTGATTTCTCTGACAGCTGCCCCGTTCCCGATTTAATATGTAATGAGAAACCATCCGTATCGCCGTGCAGTGAGTTATCAGAGAACGGCGACAACTCAACCGATCGTACCTCAATCTCGCCTAAACCAGAGTGTAGCCAAATAAGTAGTAGTGTAAATGTTGCACAGAAGAAAACTCAAAGTCCTCAAAGACCGTACAGACACAACACATTAAGACTGAACAATATTTTTGTGAAGAAGCACAAGAAAGTGTTGCAAATAAAGAATGCCAAACCCTTTCCTGTAAGTAGTACATGTGAAAATGAGATGGAACCGATGCCATCATCGTCGACCTGCAGATCGCCCGAAAATTTTACTATGAATAAAATACATTACATAGACAAGGTTGAAAAAGAGATAGGCAATGTATTGCACACTATATCTGTGGAGGTGATCAAGGAGAATGATGATAACAATGACTTCGATGCTGACACAGAGGAACAGTCGATGGATATTGAACCGGTAGCACCGTCGAGTATAAGTCATTCCAATGAGTTTTCATCAAACGACATGGTGCGTGTGAAAGAAGAGATAAATACGAGCAACGAAGGAGGGTTCAGCAACCAGGGCCGCGTGCTCACGCGCCTCGAAACATTGCGTCCGATCAATGTTATAACGTACGGAAACATACCGACGGAGGATTTCGATGACGAATCAAATGACAGGGAGTTATTAGACCTCGAAGCGGCATCTAAAAACAAGCAGTTCGTTACAATGATGAACGAGAATTACTTCGGGGACAATATTTACGCGGATTACTTCACACCCGATCGGGTGGAGTCGTTTAATGCGCGCGAGTCGGCGGGGTACAAGGAGCCTCCTAAAGATGGCATGTACAACATTTGGGGTGAACCATCTCAGATGCAGAAAGAGAATGAGTTCGTACTCCCGAACTTTATACACGAGAGCTATAAGATAGCCGAGAGTGCTACAGGGGAGTATTCGGAGATGGGTTCTAGGGAGGGAGCGGGGGAAAGGAATGTTGACGGGTGTGAGAGGGACAGTAAAGTGGATGTGTTGAGTGAGAGTAGGAGCGAGAGTGAGGCTCCGCTGAACATCTGTGCGGATGAGCGGATGCCGCCGCGCGGGGAGCTCAGTGGACAGGAGAGTAATGGCGATATGGAGTCTCCTTGGACTGGGATGTACAGCGAGATGGCGCCGACGGAGCCGTACGATCTGATCGCGCGCGAGAGCTGGGTCTCGGACGGGTCGGATTTGGACGCCACCGAGAAGAGGGATACACTGGAGGAGGAGCTCCAGTTCGCCAAGTCCCGGCTGTACACGTGCGCGCAGTGCCGCGCGAAGCTGCCCTCTATGAAGGAGCTGCGCGCGCACAAGGCGCTGGCGCACGCGCTCCCCGCCGCCAGCGCCACCTACAGCCGCCTCGTCACCGCCAGGACCATCAAGAAAGAGGAGAGGCACGACAAGATTACCCTAACCAATAACCTCCTAACATTGGACACCAAAGAATCAATAACATCGACAATACTTGAAGTGTACGAAACCATAGACGAGTCGAAGCCCAAGATCGAGGGTCTCATCAAACAGGAGCCGAAGCGGCGGCGGAGGGATTACGTGTGTCCCACATGCAAGGTGGACCAGCTGAACGACCTCGCGTTCCACGAACACTTGAAGATACATCCACTGGAGTGCCTCACGTGCGGAAAGTGCTTCTTCCGAAGGGCCAATTTGGCGCTGCATATAAAGACGCATTTAGGAATTAGAAATTACAAATGCGACGTGTGCGAGAAGCGGTTCATGACGCGCCAGAAGCTGGCGGAGCACCACAACGTGCACACGGGCCGCGCGCCCGTCAAGTGCACCGTGTGCGACGACACCTTCCGCCGCTACTCCAACATGGTGCAGCACAGGGACCGGCACCACCTGCAGAAGCGCGCCAAGGTGCGCGACTTCGTGTGCCAGTGCGGCGGCGTGTTCCACTCGCGCGCCAAGCTGCTGTGGCACCGCGAGACGCACGACGACAAGCCCAAGGCGTGCCTCTACTGCAGCGACAAGTTCGTGCACGCCGCCTCGCTCACGCGCCACGTGCGCCGCTCGCACAACGAGTACTTCCTCTCCGACCGGCTCAAGGGCAAGGCGGAGAACGTGCCTTGCCCCGTCTGTAAGCAGGTATACCTGAGAACGAACCTGCGCGCCCACCTCCAGATACACAGCGGGCAGCGCCCCTTCCACTGCGTCATATGCAACAAGTCGTTCACAACCAAATGGAACCTGAAACTCCACCGGTGGACCCACATGAGCCGCTCCGCGAAGCCCTTCAAGTGCACACTGTGCAAGGGCGCCTTCATCCGCCAATCGGAGTACATCGCACACATGAACGCCCACAAGTCCGTCAGACCGTACACCTGCAACTACTGCGGCTGCCAGTTCATAAGGAAATACAACTGCCAGCGGCACGTCCGCGAGCACGAGATGGCGAAGAAGTACGTGTGCAAAGTACCCGAGTGTGGTAAGTCGTTCCATCGTAGCTATTATCTGTCCGAGCACATGAAGGTGCACAGCGGGGCGCGGCCGTTCTCATGTAACATATGCGGGAAGACTTCGAGCAATAAGTCGAACCATAATAAGCATGTTAAGATACATCACGCGCGGGAGCCCGTCGCTACCGAAGCGTAA
- Protein Sequence
- MDQLVQCPVCTLFLHNGMTLESHLDTHPKDQVIKALCSLTTKGSNYGSRTSTPLHSERSYRSRSRTPATEDSGRWNGSHRSTEPDRYWRRTPSRTPKTNPISSVSRNSTPDIRINEMNFESGSINSAGTHTPFVMKADKIQQTYQPPPVTDFDPQYVYYPDQQEDREIKYSRSAEYNAMDSTNNVFTYNMPTIGTGVKLLPAVPRRTNDIVKILPKQNNILLKTNMGGVQYISPAVKPMHVVVPTAPTFLQKNVQNNMIVTSNIPNAQVQIETKSIAPSLTTNLNQMTSNTFTPGTTVVTQNSQIIYREMVHNIDGKPFITSMPTVLSGHDNVTNVAQASSMYQNVMVVDQFGNTSCMYTTPQQILPKSCTTSIYNNNGPLVPGIHMEKPVANLNDPKTLIIEVGPMLPAHDHASSSSCEASVSSIRQAETSTTEKLERPTNEVEMRNDTPGASKGLKILSNIKVEVPVQHHKNMVNTIMDLTGPSETDYSVRPASPDKILPDLDDNNQTESEKILPDYDDKTQMMANPERILPDIDDNNQIIMDESTQPSMSSADSIVSHSFSVIKNVGNPPSYKDLSKNSDSKMDADFSDSCPVPDLICNEKPSVSPCSELSENGDNSTDRTSISPKPECSQISSSVNVAQKKTQSPQRPYRHNTLRLNNIFVKKHKKVLQIKNAKPFPVSSTCENEMEPMPSSSTCRSPENFTMNKIHYIDKVEKEIGNVLHTISVEVIKENDDNNDFDADTEEQSMDIEPVAPSSISHSNEFSSNDMVRVKEEINTSNEGGFSNQGRVLTRLETLRPINVITYGNIPTEDFDDESNDRELLDLEAASKNKQFVTMMNENYFGDNIYADYFTPDRVESFNARESAGYKEPPKDGMYNIWGEPSQMQKENEFVLPNFIHESYKIAESATGEYSEMGSREGAGERNVDGCERDSKVDVLSESRSESEAPLNICADERMPPRGELSGQESNGDMESPWTGMYSEMAPTEPYDLIARESWVSDGSDLDATEKRDTLEEELQFAKSRLYTCAQCRAKLPSMKELRAHKALAHALPAASATYSRLVTARTIKKEERHDKITLTNNLLTLDTKESITSTILEVYETIDESKPKIEGLIKQEPKRRRRDYVCPTCKVDQLNDLAFHEHLKIHPLECLTCGKCFFRRANLALHIKTHLGIRNYKCDVCEKRFMTRQKLAEHHNVHTGRAPVKCTVCDDTFRRYSNMVQHRDRHHLQKRAKVRDFVCQCGGVFHSRAKLLWHRETHDDKPKACLYCSDKFVHAASLTRHVRRSHNEYFLSDRLKGKAENVPCPVCKQVYLRTNLRAHLQIHSGQRPFHCVICNKSFTTKWNLKLHRWTHMSRSAKPFKCTLCKGAFIRQSEYIAHMNAHKSVRPYTCNYCGCQFIRKYNCQRHVREHEMAKKYVCKVPECGKSFHRSYYLSEHMKVHSGARPFSCNICGKTSSNKSNHNKHVKIHHAREPVATEA
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00622251;
- 90% Identity
- iTF_01180592;
- 80% Identity
- -