Pgno002262.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Pheosia gnoma
Gene Symbol
PLAGL2
Assembly
GCA_905404115.1
Location
FR989922.1:2675084-2679067[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 0.04 2.3 8.9 1.5 1 23 94 117 94 117 0.94
2 18 0.0068 0.39 11.3 3.2 2 23 189 210 188 210 0.97
3 18 0.00012 0.0067 16.9 0.1 1 23 214 236 214 236 0.98
4 18 0.14 8.3 7.1 3.1 1 23 241 264 241 264 0.86
5 18 0.00059 0.034 14.7 0.2 2 23 272 294 271 294 0.95
6 18 1.2e-05 0.00069 20.0 3.1 2 23 302 324 301 324 0.96
7 18 0.00033 0.019 15.4 2.6 1 23 330 352 330 352 0.97
8 18 5.4e-05 0.0031 17.9 2.3 1 23 358 380 358 380 0.98
9 18 0.93 53 4.6 2.5 1 23 461 484 461 484 0.91
10 18 0.39 23 5.8 0.7 3 23 512 533 511 533 0.94
11 18 0.0019 0.11 13.1 1.0 2 23 556 577 555 577 0.97
12 18 0.00094 0.054 14.0 0.2 1 23 581 603 581 603 0.98
13 18 0.027 1.5 9.4 1.2 1 23 608 631 608 631 0.84
14 18 0.00039 0.022 15.2 0.2 2 23 639 661 638 661 0.95
15 18 0.00031 0.018 15.5 2.3 2 23 669 691 668 691 0.95
16 18 0.00011 0.0064 16.9 2.9 1 23 697 719 697 719 0.98
17 18 0.00013 0.0074 16.7 2.8 1 23 725 747 725 747 0.99
18 18 5.3e-05 0.0031 17.9 4.9 1 23 753 776 753 776 0.98

Sequence Information

Coding Sequence
ATGCGTCGTCGCCTGGGCAGGCCAAGGAAACGTCTCCGCGACGACTCGAATGCATTAGGTACCGGCTGCAAAACAGAAATTAAATTACGTCCAGCTATAAGGAAAGTAACACCCAAAGCGTCAAAGAAGTCTGTTAACACCGATAAGACAGGTCGAGAGGATGAAGTTTCAACTGAACCTCTGAGTTCGCGCAAGGAGATAGCAATGCATTTACATAACATTAGAACCATACTCTTGAACTCAAACGCGACGCCGATAAGGAGCCACGGAGGCTTCGGATACAAGTGTTGCTACTGTGACGAGCAGTACCTCAATCCGGCGGAGCTCAAAGTTCATACAATATACAGACACGGCAGCACAGCCATAAGCAAATTCATGAAAGGTACCCGTATGCTTTCATTTGTCGTCAAACTGGACATCACTGAACTAACTTGCCGGATCTGTAGTGAAAAAATTGATATATTCGAAGATTTTATAGATCATTTGATAGACGAGCACGATAAAAAAATATTTGATGGCATCAAAAACCATGTGCTGCCGTTCAAATTTGATAGCGACGCGCTCAAGTGCGTGATATGTTCTATACATTTCGACCATTTCAAATTACTGCAAGAACACATGAACTCGCACTACAGTAACTACATTTGCAAGATTTGCAACACACCGTTCGTAAACAAAAATCTTTTAGGAAACCATATAGCTCGGCACAAACAAGGAGAATTTCAATGCTCCTTCTGCCCTAAAGTGTTCGACACTCATCCCAAGAAGTCGAACCACGAGAAGTTCGTACACATCACCGACCAAAGACGCAACAAATGTCCGATCTGCGGAGAGAAGTTCGTGAGTTACGCCAACAAGAACTATCACATGGTCAGAGAGCATGGGACCGAACCTCTCATACTGAAATGTAAGGCTTGCGACAAAACATTTACCAGGCAAGACAAACTGTTCAGGCACACGAAACGAGACCACTTGTTGGAGCGACGGTTCGAATGTGAGCACTGTGATATGAAGTTCTATGAGAAGAGGGATCTCAGTAGCCATATGGTTAAGCATACAGGACTTAAAGAGCATAGGTGCGAGCTTTGCTTGAAGGCGTTCGGGAGGAAGTATACGCTGCAGCAACATTTGAGGATACACGCGGATGATAGGAGATTCAAATGTACAGGCTGCAATACAGAAATTAAATTAGAGCCAGCTGTAAGTAAAGTCACAAGTAAAGCATTAAACGATTGGACTGTTACCATCAAACAAAGATGTCTAAAGAGAGAACAGTCTGTAAGAAGAACTTACAAGGAGATAGATATGCATTTACATAACGTCAGAACGATACTCTTACATTCCAACGCGACGCCAATAAGAAGCCACGGAGGCTTCGGATACGCGTGTTGCTTCTGCAAAGACCACTACGTGAATGCGTCTGATCTCAAAATTCATACCATAGACACGCACGGTAGCACAGATATTAGCAAATTCATGAAAGGTACCCCTATGCTGACATACGTCGTCAAATTAGACATCACTGGATTACTTTGCAGGATCTGTAAGAAACATATTAATAATTTAGATGCTTTGGTCGATCATTTAACAAATGAACACAATAAAAAGATATTTAACGATATCAATGATCATATTATACCGTTTCAATTCGATAGCGATAAACTCAAATGCGTGATCTGTTCCATCAACTTCGATCATTTCAAGTTACTACAGGAACACATGAACGTACACTATAGGAACTACGTTTGCAGGCTCTGCAACGCACCGTTCGTCAACAAACGTACATTAGGAAGTCACATGGCTCGGCACAAGCAGGGAGAGTTTCCCTGCACCTACTGCCCTAAAGTGTTCGACACTTATCCGAAGAAATCAAACCACGAGAAGTTCGTACACATTTCCAACCAAAAGCGTAACAAGTGTCCGATCTGCGGGGAGAAATTCGTGAGTTACGCGAACAAGAACGATCACATGGTCAAAGAGCATGGGGCTGAACCGCTTATACTCAAATGTATGGCGTGCGACAAGACGTTTACTAGACGGGACAGACTGTCGAGGCATACGAAACGCGATCATTTGATGGAGAGAAGGTTCGAATGTGATCACTGCGATATGAAGTTCTACGGAAAGAAGGATCTTCGTACGCACATGGTGAAGCATACAGGGGTAAAAGATTATAGGTGTGATTTTTGCTTGAAGGCATTTGGGAGAAGGCACACGTTGAAGGAACATTTGCGGATACACGCGGATGATAGGAGATTCAAATGTGGGCATTGTGGACAGGCGTTTGTGCAGAAGTGTAGCTGGAAAAGTCATATGCGGTCGAAGCATGGGGAGTATGTCTAG
Protein Sequence
MRRRLGRPRKRLRDDSNALGTGCKTEIKLRPAIRKVTPKASKKSVNTDKTGREDEVSTEPLSSRKEIAMHLHNIRTILLNSNATPIRSHGGFGYKCCYCDEQYLNPAELKVHTIYRHGSTAISKFMKGTRMLSFVVKLDITELTCRICSEKIDIFEDFIDHLIDEHDKKIFDGIKNHVLPFKFDSDALKCVICSIHFDHFKLLQEHMNSHYSNYICKICNTPFVNKNLLGNHIARHKQGEFQCSFCPKVFDTHPKKSNHEKFVHITDQRRNKCPICGEKFVSYANKNYHMVREHGTEPLILKCKACDKTFTRQDKLFRHTKRDHLLERRFECEHCDMKFYEKRDLSSHMVKHTGLKEHRCELCLKAFGRKYTLQQHLRIHADDRRFKCTGCNTEIKLEPAVSKVTSKALNDWTVTIKQRCLKREQSVRRTYKEIDMHLHNVRTILLHSNATPIRSHGGFGYACCFCKDHYVNASDLKIHTIDTHGSTDISKFMKGTPMLTYVVKLDITGLLCRICKKHINNLDALVDHLTNEHNKKIFNDINDHIIPFQFDSDKLKCVICSINFDHFKLLQEHMNVHYRNYVCRLCNAPFVNKRTLGSHMARHKQGEFPCTYCPKVFDTYPKKSNHEKFVHISNQKRNKCPICGEKFVSYANKNDHMVKEHGAEPLILKCMACDKTFTRRDRLSRHTKRDHLMERRFECDHCDMKFYGKKDLRTHMVKHTGVKDYRCDFCLKAFGRRHTLKEHLRIHADDRRFKCGHCGQAFVQKCSWKSHMRSKHGEYV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01180501;
90% Identity
iTF_01180501;
80% Identity
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