Pgno016111.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Pheosia gnoma
Gene Symbol
egg
Assembly
GCA_905404115.1
Location
FR989923.1:1729113-1769057[-]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 1.7 6.4e+03 -3.1 0.1 28 38 1615 1632 1591 1633 0.61
2 2 4.2e-14 1.6e-10 40.5 0.0 4 75 1664 1728 1661 1730 0.90

Sequence Information

Coding Sequence
ATGAGTGCAGCGAATAAAATAGAAGATGAAAACATTATTATGGAAGCAGGAGAAGCAGAAATTTCGAATCAAAATGTGGCTACAATTTCAGAAGGTATTACAGATACATCTTTTCACAAAAACATTATAAATGAGGATGAAATTGGTGGTAAAACTAAGTTTACACCTCATATACAGTCTTCAGACAAAGCATTCGTCAATATTGATAATTCAGATGCTGTAAATCAAAATTTAAATCCAAATGCTTCAGACAAATCCTCTGGGGACCATCCAATACAGTCTGACAATATTAAAGTCATTGAAGATAATAAAACAGATAAATCAAGAGTGGTTGTTGATGATATCTCAATTAATGATAATGATATTACATCTCAAGATGTCAATAATGATATCATCAATAAAAACATGATTGACCAATCATCTCAAAGTAAAGAAGCTGGTAATACAATTGCACCAGCAGCATTCCAAGCTGATATAAAACTAGACTACAATGATGATGATGACATGGAATTAAAATGGGATGAAGGTAATGATAATTTTGTGGGTAATGATGATGATTTAATGAAAGATGGCAGGGAGTGTGATGTTAGTAATGAAGAACAGAAAGTTGAAACATTAGCAGACGAGTCAAGTATGGATATAGATGATAATAATGATCCAGATTTGTTGAATGATAATCCAATAATAAACAAAGATAATAATGATGTTGATTCAACTATTGGTCATTCAATTGAAAATACAGAAAAAGAGACTTGGGAAAAAACCCAAAATGTTAAAAATGTAGACATGATTAATGAAAATTTAACTAAAACTAACACTAATACAGCCATATCAAATGATAATAAAGATCTGATAGACCTGAAAACCCCAACCAATGAGGAAGCATCTTCAAGTCAAGATATGTCAATAGAAGATACCAGCCAGCTAATTACAAAATCCCACGGAATTCACGGACCAGATGTAATGCTAGAAATACCAACACAAGAACTAATTGATATTGATGATAATGATCTATCTATCATTCTAGATCAATCAGATGAGAGTCCAGATGTAAAAAATTGTACAAAGATGGATGAGGAATTGACAGAAAAGGGTGCTGCAGATGATGGTAATATGACAGTAGAGGAACCAATAGTTACTCGCAAAGTGGTCGAATTAGAAAATGTAAAGGACTTAGAAGCAAATGTGCCTGAGAAAGCATCTGATAATGTTAATGCAACACTTGACGTAGGATCCCAAATCGAGAACCCAGATAAAGTATTAACGTTTAATACCGGCGACAAAATGGCCTTGGACACATCTCAAAAATTGCCTGGTGAGACATCTACTAAGATAAATGACAGTCTCAACAAATTAGGGCCCGCAGACAATTTGGATGAGAAGCCTAAAGTGTCAGAAAATACTGACTTAGCACCATCTAATAGTTTACCTGCAGACATAACAAATAAGTTATCTGAAGTAACTGTCAGTATGGATAAAACTGTGTCATCTAGTAACATGTCCCCAGACATAACTAACCAGGTACCAGATGTGTCAGAAAGTAACAATCCACAAGCAGCCTCGTCAGATAAGTTGCTTCAAGAGACTGACAATTTGGATACACCAGTGTCATCCAACAAGATAACTCAGGATAAATCTGACAATGTCCCTGAAGCCTCCGATAATATCAACCCACGAGTTACTACATCAAATGAGAATCCTGAAGTGACTGACAATTTGGGTACATTATTGTCAATCAATAAGATAACCCCAATTACACCTGACAATGTCCCAGATGTGTCAGGCAGTATCAGCTCGCAAGCTACTACATTAAATGAGTCACCTAAAGTGACTGACAACTTGGGTACATTATTGTCAACCAATACAGTAACCCCAGATGCATCTCACAAAATGCCCGAAGCACTAGATAGTATCACTCCACAAGTTACTGTATCAAATGAATTGCCTGAAGTGACTGATAATTCGGGTACATTAGTATCTTCTAACAAGATGACCCCAGATACATCTGACAATGTCCCCGAGGTGTCAGATACTATCAACATACAAGCAACTACGTCAAATATGCTACCTCAAGTGACTGACGATTTGAGTACATTAGTTTGTTGTAACAATACAACCCCGGATGGATCTGACAATGTCCCCAAGGTGTCAGGCATTGTCAACCAGCAAGATACTCCATCAAATGAGTTACCTCAATCATCTGAGAAGTTGGTGTCATCTGAAACAATGATCCCGGACACATCTGATGAATTGCCTGAAGTGTCCGACAAAAGCAGTAATCAAATTTCAACCGCCGAACATTCAGAAGACTCGAATGCTCAACATTCAGAGTCAGAAGCGAACAAAGACGAGAAAGAGACGGACGTATCTCCCGCTGTGGAGAGCGAGAGAGAGTTCCAATTTATGATCTCCAGTGTTGAGAGTCAGGGAGCAAATAAGACTGACTTAGAAGGCAATGAGAAACAACAAGTGGATGGCGATGGAAGCAAACAGGCAGCATCAACAACGAAGTCTCCGGAGATAATATCTTCAACTGATCAAAGCAAGCTATCTCCGAGTAAGGTTAAAAAGCTAGAATTATCTTCGAGCGCACAGCCAGTGTTCAACATTGTCGACCTAGAAGAGAGCTCTTCAGAGGATGACATCCAAGAAATAAACAAAGAACCGGAACCAACAACTCCTAAGCCGGAAGTCACCGACATTGATGGCGTGACGAGCGTCAATCTACCCAATGACATCGAAGTGATGTGCACATCCGCCGGAAGTACGTCGGAGATCGTCACGAAAGAGGGGGAGGTTGTGATCAGTGGAGTCCCTAAGCCGCCCCCCGTCAAACCTGCAAGAATTAATACTAGTGAAGTCTCCATTAAAACCGCCAGCGTGGTCACGGACACTCTGATCATACCCGAAGCGAAGTCAGCTATCAGTGATAAGACGCCTCCAGACACTAGGGTTAAGCCTAAATTGTGTCTAGAAATATTCAGCTTGGACTCTGACGAGGAAGACACAAAATCATCTGTTAAAGAACCACCGAGCGTCCCCGCCCCTCCTCCCCCCGAGCCGGCGGCGGCGGCCCCCCCCCGCGAGGCGGGCAGGTGCGCGAACCCGCGCTGCGGCGGCGGGGCGGGGGCGGCGGGGGCGGCGGGGGCTGCGCGCGCGCCGGCCGACCGCGCCGCGCGCCTGCACTACGGCGTCACGCGCCGCGCGCGCGCCCTGCTGTGCCAGCCCTGCGCGAGCGCAGTGCAACACGCTAAACAGAACCTAATAAGAGGCATCAAGGATTTCACTCCGCTACTAGAGTTGGGCGTGGACAAGTTGTCCCAAGAGCTAGTGGAGATCTCGGACTCGGAGTCCGAAGACGAGTCCGAGGAGCCGAGACTGCCGAGCGACACTATTGGCGAGAAGGGCGCTAAATTACTAGAAGAGAATCTGGCCGCTATTATCAATGAGACATGGCAGAAATATAATATGGACGTCAGACTCAAGGACACACACGACATATTGGACTCCGAGCTGCAGAAGCTGGAGAACGAGAGCAAAGAAATTGATCAGATGTTGAACGACTGCCAGTTGGCGACCGACAAGTTGCGCAACGAGTTGTACGCTACGTTCGAGCGCGGGAGCGTGCAGCTTCCCGGCTTCACTATATACGATACGCCCATGTACAACTATGTTGGTCCGGAAATAGAGACGACGGCCACACCGCCGCAGCCGGAACCGGTTCGTCAAAGCAAGAGGCGTTTGTCCATACCGATTGAGGTTCCCGCCAAGAAGCCCGCCATACCTCTCGGGTACATACCAATAAACACAGATAATACACAACACAATAAAGAAGAATCTAAATCCATGCCGGGCCTTGAAGACAAGGCTGATGATGATAGAGAGGTGTCGGTGGTGAAGCTGTCGGCGGAGGCTGCGCCGGCGGACCTGCCGCCGCCGGGCGAGATGTCCCGGCCTCCGCTGCGGGTCGGCGCCAGCGTGTTCGCGATGCGCAACGCCTTCGGCCCCTGGCTCAGCGGGAAGATACTCGAATGCCAGCCCAAGCATGCTTCGACGGCGCCGTACACGATGTGCCGCGTGAAATTCGACCATAAAGCAAAGAATCCGTGCAAGATTCTGTCCGCGAGGTGCCTCGCTTACTCCGAGCCGGCGGACGTGCGAATGACAATAGGTACAAGGATTATCGCCCTGTACAAAGATCCCAGTAACTTGAAAAGGGAGCAATACTTTTCGGGTGTTGTGGCTGAAATACCGAACCCTGTGAACAGCTATCGGTACCTGGTGTTCTTCGACGATGGCTACGCCCAATACGTCCAGCATAGCCTGACTCGCCTGGTCTGCGAGAGCTCGAGCCTGGTGTGGGAGGAAGTTCATCCATTCTCCCGGCAGTTCGTCAAGGACTATTTGATGGCGTACCCAGAACGGCCCATGGTCCGGCTGCACGAGGGGCAGAGCCTCAAGACCGAGTGGAACGGTAAGTGGTGGGCGTCGGTGGTGGCGCGCGTGGACGCGTCGCTGGCGCAGGTGGTGTTCCCGGGCGAGGGCGGCGGCCGGCGCGAGTGGGTGTACCGCGGCTCCACCCGCCTGGCGCCGCTCTACCTGGAGTTCCAGGCCGCCGGCCGCCACCGCCAGCGCCCCATGCCGCGGACCAAGGCGCAGACCGGGACCGACATGCCGTACGTGGAATACACGCGCTCAGACGAGCAGGAGAGCAACAAACTAAAGGATATACAAACGGAACAACAGCAAAATGAGCAGGAACTGCGGCGGCAGCGTGCGGTGGCCAAGAAGTCCACCGCCAGCCCCGCGCCGCCCGCGCCGCCCGCCCCGCACGCCCTCCCCCCGCAACAATCCAACCTCGACACCGTCACCAGCAGGGTCGTGTATTACACGCCGAAAGCGGCCATCAAGCCGTACAAAATGGTGCCTCACACTTGCGGTCCCAAATGCAAGAGGACCGATGTTCTGTCGCTAAAGGAACTGCGCACTTATAACCCGCTGGCTAAGCCGCTGCTGAGTGGATGGGAAAGACAGATAGTCCGCTACAAGGGGCACAAGGAGGTGATGTACCGCGCGCCGTGCGGGCGGCGCGTGCGCGGCGTGCGCGAGCTGCACCGCTACCTGCGCGCCGCGCGCAGCGACCTGCCCGTCGACCTGTTCGACTTCCACCCCGCCACGCACTGCCTCGCCGAGTTCGTGCTCAACAAGTGCCGCGTGGGGAAGAAGGACCTCTCGCACGGCAAGGAGAACGTCCCGGTGCCGTGCGTCAACTATTACGACGACTCCTTGCCGGAGTTCTGCTCCTACAACACGGAGCGAACCCCCACGGCCGGGGTGCCACTGAACCTGGACCCCGACTTCCTGTGCGGGTGCGACTGCGCCGATGACTGTGCGGACAAGTCGAAGTGTGCGTGTTGGAAGTTGACCCTGGAGGGGGCTCGCACCATCGGCCTGGAGGGACCCGGCGTGGGGTACGAGTACAAGAGGCTGCCCGAGCCTCTGCCCTCCGGGATATACGAGTGTAATTCCAGATGTAAATGCAAGGCGACTTGTTTGAATAGAGTAGCACAACATCCGCTTCAGTTAAAGTTACAGGTCTTCAAAACTCTGAACCGTGGTTGGGGTATTCGCGCATTGAACGACATCCCTAAAGGCGCATTCCTGTGCGTATACGCCGGTAATCTGCTCACAGATGCAACCGCTAACTTGGACGGCTTGAACGAAGGTGATGAGTATCTAGCGGAGTTGGATTACATCGAAGTAGTGGAGCAGATGAAGGAGGGCTTCGAGGAGGACATCCCCGCCGCCGACAAGAGACTTGACAAGAAGGAACTGGCGAAGCAGAACGACGAGGAGTCCTCGGAGGAGGATATCCCGTCCTCCTCGGACGAGGGCCGAGCCTCCAAGAGCGACAAGGAGGACGACGACTTCATGCCGGGATACATAGGGCTCGGCGTCACCAAGTTCAACAAAGCGTTACGGAAACGCGACAAAGCGAAGAAGGAAGAGGAGGAGAAAGATAAAGGGAGTGAGAAAGAGAAAGAGAAGGGTAACTCCAAGAATGAAGAGGACTGCATCACCATTAGCGATGATGAAGAAGTGAGGGAGCCATCTCGATTCACAGCGCAAGCCGGCATGGGGGCCAACCAATTCATATCTAAATACAGGTCGGTTCGTTCGCACTTTGGGAAGGACGAGGCGTGCTACATCATGGACGCTAAAGTCCAAGGCAACATCGGCAGATATCTCAATCACTCTTGCACGCCCAACGTGTTCGTTCAGAACGTGTTCGTGGACACGCACGACCCCCGCTTCCCCTGGGTCGCGTTCTTCGCACTCTCGCACATCAAGGCGGGCACGGAGCTCACGTGGAACTACAACTACGACGTGGGTTCGGTTCCCGGGAAGGTGCTGTACTGCTTCTGCGGCGCGACCAATTGTAGGGGGCGGTTGTTGTAA
Protein Sequence
MSAANKIEDENIIMEAGEAEISNQNVATISEGITDTSFHKNIINEDEIGGKTKFTPHIQSSDKAFVNIDNSDAVNQNLNPNASDKSSGDHPIQSDNIKVIEDNKTDKSRVVVDDISINDNDITSQDVNNDIINKNMIDQSSQSKEAGNTIAPAAFQADIKLDYNDDDDMELKWDEGNDNFVGNDDDLMKDGRECDVSNEEQKVETLADESSMDIDDNNDPDLLNDNPIINKDNNDVDSTIGHSIENTEKETWEKTQNVKNVDMINENLTKTNTNTAISNDNKDLIDLKTPTNEEASSSQDMSIEDTSQLITKSHGIHGPDVMLEIPTQELIDIDDNDLSIILDQSDESPDVKNCTKMDEELTEKGAADDGNMTVEEPIVTRKVVELENVKDLEANVPEKASDNVNATLDVGSQIENPDKVLTFNTGDKMALDTSQKLPGETSTKINDSLNKLGPADNLDEKPKVSENTDLAPSNSLPADITNKLSEVTVSMDKTVSSSNMSPDITNQVPDVSESNNPQAASSDKLLQETDNLDTPVSSNKITQDKSDNVPEASDNINPRVTTSNENPEVTDNLGTLLSINKITPITPDNVPDVSGSISSQATTLNESPKVTDNLGTLLSTNTVTPDASHKMPEALDSITPQVTVSNELPEVTDNSGTLVSSNKMTPDTSDNVPEVSDTINIQATTSNMLPQVTDDLSTLVCCNNTTPDGSDNVPKVSGIVNQQDTPSNELPQSSEKLVSSETMIPDTSDELPEVSDKSSNQISTAEHSEDSNAQHSESEANKDEKETDVSPAVESEREFQFMISSVESQGANKTDLEGNEKQQVDGDGSKQAASTTKSPEIISSTDQSKLSPSKVKKLELSSSAQPVFNIVDLEESSSEDDIQEINKEPEPTTPKPEVTDIDGVTSVNLPNDIEVMCTSAGSTSEIVTKEGEVVISGVPKPPPVKPARINTSEVSIKTASVVTDTLIIPEAKSAISDKTPPDTRVKPKLCLEIFSLDSDEEDTKSSVKEPPSVPAPPPPEPAAAAPPREAGRCANPRCGGGAGAAGAAGAARAPADRAARLHYGVTRRARALLCQPCASAVQHAKQNLIRGIKDFTPLLELGVDKLSQELVEISDSESEDESEEPRLPSDTIGEKGAKLLEENLAAIINETWQKYNMDVRLKDTHDILDSELQKLENESKEIDQMLNDCQLATDKLRNELYATFERGSVQLPGFTIYDTPMYNYVGPEIETTATPPQPEPVRQSKRRLSIPIEVPAKKPAIPLGYIPINTDNTQHNKEESKSMPGLEDKADDDREVSVVKLSAEAAPADLPPPGEMSRPPLRVGASVFAMRNAFGPWLSGKILECQPKHASTAPYTMCRVKFDHKAKNPCKILSARCLAYSEPADVRMTIGTRIIALYKDPSNLKREQYFSGVVAEIPNPVNSYRYLVFFDDGYAQYVQHSLTRLVCESSSLVWEEVHPFSRQFVKDYLMAYPERPMVRLHEGQSLKTEWNGKWWASVVARVDASLAQVVFPGEGGGRREWVYRGSTRLAPLYLEFQAAGRHRQRPMPRTKAQTGTDMPYVEYTRSDEQESNKLKDIQTEQQQNEQELRRQRAVAKKSTASPAPPAPPAPHALPPQQSNLDTVTSRVVYYTPKAAIKPYKMVPHTCGPKCKRTDVLSLKELRTYNPLAKPLLSGWERQIVRYKGHKEVMYRAPCGRRVRGVRELHRYLRAARSDLPVDLFDFHPATHCLAEFVLNKCRVGKKDLSHGKENVPVPCVNYYDDSLPEFCSYNTERTPTAGVPLNLDPDFLCGCDCADDCADKSKCACWKLTLEGARTIGLEGPGVGYEYKRLPEPLPSGIYECNSRCKCKATCLNRVAQHPLQLKLQVFKTLNRGWGIRALNDIPKGAFLCVYAGNLLTDATANLDGLNEGDEYLAELDYIEVVEQMKEGFEEDIPAADKRLDKKELAKQNDEESSEEDIPSSSDEGRASKSDKEDDDFMPGYIGLGVTKFNKALRKRDKAKKEEEEKDKGSEKEKEKGNSKNEEDCITISDDEEVREPSRFTAQAGMGANQFISKYRSVRSHFGKDEACYIMDAKVQGNIGRYLNHSCTPNVFVQNVFVDTHDPRFPWVAFFALSHIKAGTELTWNYNYDVGSVPGKVLYCFCGATNCRGRLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01180333;
90% Identity
-
80% Identity
-