Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.0098 61 4.6 0.0 23 48 9 34 4 38 0.87

2 7 9.8e-05 0.61 11.0 0.1 25 44 40 59 34 64 0.86

3 7 0.079 5e+02 1.7 0.7 21 39 64 82 60 96 0.75

4 7 0.00034 2.1 9.3 0.1 22 44 131 153 120 157 0.90

5 7 0.012 76 4.3 0.0 26 45 162 181 155 186 0.86

6 7 0.00069 4.3 8.3 0.1 22 46 187 211 172 215 0.87

7 7 0.14 8.8e+02 0.9 0.1 26 48 219 241 214 243 0.85

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.0098	61	4.6	0.0	23	48	9	34	4	38	0.87
2	7	9.8e-05	0.61	11.0	0.1	25	44	40	59	34	64	0.86
3	7	0.079	5e+02	1.7	0.7	21	39	64	82	60	96	0.75
4	7	0.00034	2.1	9.3	0.1	22	44	131	153	120	157	0.90
5	7	0.012	76	4.3	0.0	26	45	162	181	155	186	0.86
6	7	0.00069	4.3	8.3	0.1	22	46	187	211	172	215	0.87
7	7	0.14	8.8e+02	0.9	0.1	26	48	219	241	214	243	0.85

Coding Sequence: ATGCATCGCTTTGTTCACGAGAAAAATCCAACACCTTGCGAAGTGTGCGGTAAAGTTTTTGAGACCAAACATAGTCTGCGCAAACACAAGTCCTACTGGCATAAGTCCGACTTAAATTTACAGTGTAAATTTTGTGAGAAAGTGTTTCGACAAGAGCGCAATTTGCAAGAACATATGGCTACACATACCGGAGAGCAGCTCTATACTTGTCCCCATTGTCAAAAAGAGTCACGTTCCAAATCAAACATATGCGCCACTATATATCGCTTGCGTAATCATATTGCATCCGTACACAATAATATATATCACCATATTTGCgatatttgtggaaaaaaattcaaatcaaagaCATCCTTTCAAAAGCACTACGACGAACATCAAGGCATTGTTGAACCCCCAGCTCAATGTACAATCTGCGGTGCATGGTTGAAAAATCAACACAGTCTACGTGTACACCATCAAACGCATGAAGACACACAATTCGCCTGCGATATATGTGGTAAGTTCTTCAAGactaaaaagaatttaagtCGACACAAGGGCTATTGGCATCGACGTGAACGAAATCTTTCGTGTAGTTATTGTGACAAGGTGTTTCGTGAAAAACGTAATCTCGACGAGCACATGGCCATGCATACAGATACGAATCTGTACACATGCCCCCACTGCGGAAAAGAGTCAAGATCGAAATCAAATATGTATGTTCATATAAAAAGACAGCATCCAGATGAATGGTGGAAATCGAAACAGGAGCGTTATAAAGTAAAGCCCAATGAAGGAGGGCAAGGAGATGGCGAAGATGCGCTAAGAATCGAGTCATCACAAGTAGACACAACAGTCCCTTCTTATGCACAGGAAtgtataaatgcaaaataa
Protein Sequence: MHRFVHEKNPTPCEVCGKVFETKHSLRKHKSYWHKSDLNLQCKFCEKVFRQERNLQEHMATHTGEQLYTCPHCQKESRSKSNICATIYRLRNHIASVHNNIYHHICDICGKKFKSKTSFQKHYDEHQGIVEPPAQCTICGAWLKNQHSLRVHHQTHEDTQFACDICGKFFKTKKNLSRHKGYWHRRERNLSCSYCDKVFREKRNLDEHMAMHTDTNLYTCPHCGKESRSKSNMYVHIKRQHPDEWWKSKQERYKVKPNEGGQGDGEDALRIESSQVDTTVPSYAQECINAK

Sequence clustering based on sequence similarity using MMseqs2