Pfla020211.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Perizoma flavofasciatum
Gene Symbol
topi
Assembly
GCA_958496245.1
Location
OY292447.1:2659329-2668720[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 26 1.5 94 4.2 0.4 1 20 243 262 243 264 0.89
2 26 0.56 34 5.5 2.2 3 23 270 289 269 289 0.98
3 26 0.00071 0.043 14.6 0.2 1 23 294 316 294 316 0.98
4 26 0.22 14 6.8 0.9 3 23 322 343 321 343 0.93
5 26 0.066 4 8.5 1.9 2 21 347 366 346 367 0.92
6 26 0.0047 0.29 12.0 0.5 1 23 376 399 376 399 0.94
7 26 0.00046 0.028 15.2 5.5 1 23 405 427 405 427 0.98
8 26 1.3e-06 7.9e-05 23.3 1.0 1 23 434 457 434 457 0.96
9 26 0.2 12 6.9 0.3 2 19 574 591 573 594 0.79
10 26 2.2 1.3e+02 3.7 0.3 2 23 626 648 625 648 0.94
11 26 0.015 0.89 10.5 2.8 1 19 653 671 653 675 0.91
12 26 1.4 86 4.3 5.3 1 20 678 697 678 699 0.92
13 26 0.0015 0.095 13.6 0.2 1 23 711 734 711 734 0.93
14 26 0.00012 0.0073 17.1 1.8 1 23 740 762 740 762 0.98
15 26 0.026 1.6 9.7 3.2 1 23 796 819 796 819 0.96
16 26 0.0028 0.17 12.8 0.5 3 23 829 850 828 850 0.96
17 26 0.00023 0.014 16.2 0.0 3 21 963 981 961 982 0.94
18 26 0.027 1.6 9.7 0.0 2 23 988 1010 987 1010 0.94
19 26 0.041 2.5 9.1 0.1 3 23 1017 1038 1016 1038 0.97
20 26 0.0006 0.037 14.9 0.3 2 23 1044 1065 1043 1065 0.96
21 26 0.013 0.82 10.6 1.4 3 20 1070 1087 1068 1089 0.92
22 26 8.6e-06 0.00052 20.7 1.1 1 23 1115 1138 1115 1138 0.95
23 26 0.00023 0.014 16.2 0.3 1 23 1144 1166 1144 1166 0.94
24 26 0.051 3.1 8.8 0.2 1 23 1172 1194 1172 1194 0.98
25 26 0.016 1 10.3 0.1 1 23 1200 1223 1200 1223 0.94
26 26 0.00057 0.035 14.9 0.4 1 23 1229 1252 1229 1252 0.96

Sequence Information

Coding Sequence
atgagcCGGCAAGTGGATCTAAAAGCCTTAGTATCACACATCATAAGAGGCGATGGCTTGAATAAATGCAGAATCTGCATGGGAGATACCTCTCAAGGGCAAGTCCACCTCACCGACACAGTTATGATGGACGGAGACAAAGCCGTTACATTATCAGAGCTTCTAGAAGTCATCACAGGAGTCGAGGTGGAAAACGAAGAAGACCTGCCCTCTGCCTTATGCCTTACCTGCTCCTTCTCTGCATTTGAGGCAGCCGAGTTCCGGAACCTGGTGCAAAGAACGGAGCTCACATGGAACAATACGCTCAATCTATTACAGCATGTTCCTGACCATGAATATGCCAAAACAAGTGATAAGATTTTGGCCGTTATGGAGGAAACTCAGAAAACGACGCCACAGCAAGTATGCCATCGATGTATGTCGCACGTCACAACCTTTCTGCCTTTCCTGAAGTTGTGCAAGCAATCAGCTGCGCACTGGACCTATTTATCCGAACGATTAATCGACATTGCCGGCCATGCGAAAGCCACTACAGCATTTATCTTCATCACCGAAAACCACGTCCGAACCGTGGTAGAACGTAgggataaaagaaaaaatctaaacttgAAAAACGTAAAAATGCGCATGAATCGAATTGAGAAGGAAACGAAAAAGAGTTTAGAAACGTCTAGAAAACCCGAGTCGTTAGAGGAACTTAAGAATAGGCTATGGAAAGCGAAACTCTATACATGCCAAGAGTGTGGGTCAGAATATAGAAAGCTATGTGAGATCAATCTCCATTTAGCTAACCGTAACAAACGACTTTGCAAACACTGTTACAAAGTAGTGGACCTAAAAACTTTTTGGGAGCACCTGCGAACGCACGCGTTCCATTTCTTTAAATGTGAAGTTTGCTCGCTGCCTTTTGAGTATGAAGCGCAGTTAGAAAAACACAAGAATGTTCATAAAGGAAGGAATATGTGCGTGGAATGCAAAAGAACCTTTCCTACAGCAGATATATTGACATTACACGTCCACAAGAGGCATCAGCCAGATGTCTGTAATGCCTGCGACAGAAAATTCTCCAATCGAATATGCCTGTACAAGCACAGAAGTAAATGTAAATCAAAATCACCGAAACAATATGTCTGCGACTATTGCTTTAAAGAATTTAACGATCGAAGCGTGATAAAGTCTCACATAACATTAGTTCATTCAAAGAAATTGATGCATCAGTGTGAACAGTGCGGTAAACAATTCAACAGCGCTTGTCATTTGGAAGAACATTATGAGACGCACGAAGTTATACTGGACAGATTTATCTGCCAATACTGTGGCAAAATATTCAGTTCTTCAGGAGGTTACCGAAGACATATGAGATTAAAGCATTACAACGTGAATCCGGAGCTGAAGAGGGAAGCAAAGTACTCGTGTGAGGTCGAAGAAGATCCCATCCTCCCGCCGGGCCTCTGCCGCGTCTGTGCAGATGACGTCGTTACCGCCGCCAAATTCAAGCATCTAAGTGAAAAGTCCGCTCAAAGCTGGAGCGAGGCCACCTCTTACCTCATCGAAACAAACCTGGAAAGCGAAGATAAAACCTTATTCTATTTGTGTGAGGAAAAAGACATGATAATTTGCGAACAGAGAGTTGACACTGTTAAATCCGCTGTGACTACTCTagagtattttaaaattaatgaaaaacagAAGAAAGCTAAACGAAAAGAATCCGCTTGCGCTTGCCCTTATTGCGATAAACAATTCTCTGCTCTAGATATCCTAAACGATCACCTGACGAACGCGCAGAAGAGGGTGTGCTGCGAATGTGGTCGGATCATGGGCAAATCTGAGATGTCCAAGCACTTGCGCGATACACACGGAATAAATATAGTGGAGTGTAAGATTTGCTTTGACCAGTTCAGTAGTTATGGCGACTCGAATTGGCATATGATGCGATATCACGGCCCGAAGTCGTTCACGTGTAAGAACTGCGGACGCGGTTACAGAAACGAGAGAGGATTGCGAGCGCATTGTTATTCCCATTCGCTGTTCTGTTGCGCGGCTTGCGGTCGAAGCTTCGAGAACAACCGCTGCTACCGGCACCACAAAACCATATGCAAGTCTAAGCAGAAGTCCGAGTTCGGTATTTACGAATGCAACGACTGCGGGCTGCAGTACGATAAGAAACCTTCCCTTAAAATACACATAGTACAGAAACACTTGAACGTGCTGCCGTTTGTTTGTCAAACATGCGGTAAACGTACCTCGACTCTAGCACATTTGCGATCGCATGAAAAAGTCCACGATGATAACAGAAAGACGTTTGAGTGTCATTGCGGAGCGAAGTTTCGGACTGAGTTAGGGCATCGTCTGCATATGAGGATGCACAGTGGTTTGAAGCCGTACAAGTGCACTCACTGTGAGGAGTCTTTTATATCTGCGTCCAGGCGTTTGGATCATACGAAAAGGAGGCATAAAAGTGCGGAAGAAATGGCGCATGGATGCGATCTCTGCCCGGCTCGGTTCATCAGGCCTTGGGAGTTGAAGAAGCATTATAAGCATTTGCACAGCTCGGTGGTTGACGTACAACCGATAGTTGAGGAGAGTGAATGTCCGGGCGGCGTGTGCGCGGCGTGCGCGCAGGCGGCGCTGGCCGCGGCGGAGTTCCGGCGGCTCGCGGTCGCCGCGCGCGCGCTGTGGCTGCGCGCGGTGCACTCCCTCGCGCGTCTGCCGCTCCGCCGCCACGCTGCGCACAGCGCCCTCGCCGCCTTCCTCTCGCACCGCGACGCCTCGCTCGAGATCCTGACCGAGTTCGACGGCGAACCGGGCTCCCTCCTCGACCGGACCGTCCCGAACGGATACGTGCGGAAGCCGCGGATCCTCCGCAACGGTCCGCTGACCGCCTGCCCGGACTGCGGCAAGCGCTTCGGCAGTCCGCAACTCCTGCGGATACATCTGCAGAACAGCGATCGGAAGGACGTCTGCCGGCTGTGCGGGCAGGTGTTCCCGCGTGGCGTCGAGATGAAGAACCATCTGGAGATCGCTCATGACGAAACCCCGGTGCTGTGCGAGGAGTGTCCGACCGTGCTCTCATCGGAGGACGAATTCAAGATTCACGAGAAGAAAGCGCACGGATCCGGCGCGAAGACTTGCAGCGCGTGCGGACGCACCTTCGCGAGACTCAGCTCTTACGAGAACCACGTGGAGATGCACGTGGTGCTGGCTTGCCGTAGCTGCGGGAAGCAGTTCTCCAATCGGAGCTGCTACCGCGTGCACAGGGCTAGCTGCGAGCCGGATGCGAAGCCCCATCGGAACACAGTGCCGCGCGGCCGGCGATCCAACGTCCGCGATCCCGGCCGCTTCGTCTGCGACCACTGTAACAAGAGTTACAGCTCGCGCCCGCAACTGAAGAACCACATCCTCTGGATCCACATGGATCACCGTCCCTACCAATGCTCCTGGTGCGGTAAACGGTTCTACACTCCGGCGAGGTTGAACGAACATTCGGTTGTGCACACTCGAGTGCGAAACTTCGAGTGTGATTTGTGTGACGCGAAATTGGTGTCCAAGAGTGCTGCTATCTACCACAGAAGACGGCATACGGGGGAGAAACCGTACGTTTGCGATGATTGCGGAGCCGCCTTCATATCCTCGTCGCGGAGATTGGAACACGCTAAGAGGAAACATAATAAGGGAGtcaagtttgaatgtttggagTGCCCGGCCAAGTTTGTTAGAAGACGGGAACTGGAGAAGCACACTGAAAAGAATCATAAGCAAATTACGGTTGTTTTTCCGAAGTCGACGTGTGATGAATTGGAGAGTAAAATAATTTGA
Protein Sequence
MSRQVDLKALVSHIIRGDGLNKCRICMGDTSQGQVHLTDTVMMDGDKAVTLSELLEVITGVEVENEEDLPSALCLTCSFSAFEAAEFRNLVQRTELTWNNTLNLLQHVPDHEYAKTSDKILAVMEETQKTTPQQVCHRCMSHVTTFLPFLKLCKQSAAHWTYLSERLIDIAGHAKATTAFIFITENHVRTVVERRDKRKNLNLKNVKMRMNRIEKETKKSLETSRKPESLEELKNRLWKAKLYTCQECGSEYRKLCEINLHLANRNKRLCKHCYKVVDLKTFWEHLRTHAFHFFKCEVCSLPFEYEAQLEKHKNVHKGRNMCVECKRTFPTADILTLHVHKRHQPDVCNACDRKFSNRICLYKHRSKCKSKSPKQYVCDYCFKEFNDRSVIKSHITLVHSKKLMHQCEQCGKQFNSACHLEEHYETHEVILDRFICQYCGKIFSSSGGYRRHMRLKHYNVNPELKREAKYSCEVEEDPILPPGLCRVCADDVVTAAKFKHLSEKSAQSWSEATSYLIETNLESEDKTLFYLCEEKDMIICEQRVDTVKSAVTTLEYFKINEKQKKAKRKESACACPYCDKQFSALDILNDHLTNAQKRVCCECGRIMGKSEMSKHLRDTHGINIVECKICFDQFSSYGDSNWHMMRYHGPKSFTCKNCGRGYRNERGLRAHCYSHSLFCCAACGRSFENNRCYRHHKTICKSKQKSEFGIYECNDCGLQYDKKPSLKIHIVQKHLNVLPFVCQTCGKRTSTLAHLRSHEKVHDDNRKTFECHCGAKFRTELGHRLHMRMHSGLKPYKCTHCEESFISASRRLDHTKRRHKSAEEMAHGCDLCPARFIRPWELKKHYKHLHSSVVDVQPIVEESECPGGVCAACAQAALAAAEFRRLAVAARALWLRAVHSLARLPLRRHAAHSALAAFLSHRDASLEILTEFDGEPGSLLDRTVPNGYVRKPRILRNGPLTACPDCGKRFGSPQLLRIHLQNSDRKDVCRLCGQVFPRGVEMKNHLEIAHDETPVLCEECPTVLSSEDEFKIHEKKAHGSGAKTCSACGRTFARLSSYENHVEMHVVLACRSCGKQFSNRSCYRVHRASCEPDAKPHRNTVPRGRRSNVRDPGRFVCDHCNKSYSSRPQLKNHILWIHMDHRPYQCSWCGKRFYTPARLNEHSVVHTRVRNFECDLCDAKLVSKSAAIYHRRRHTGEKPYVCDDCGAAFISSSRRLEHAKRKHNKGVKFECLECPAKFVRRRELEKHTEKNHKQITVVFPKSTCDELESKII

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01170783;
90% Identity
iTF_01170783;
80% Identity
-