Basic Information

Insect: Perizoma affinitatum
Gene Symbol: topi
Assembly: GCA_961405105.1
Location: OY560188.1:344622-349385[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 26 1.4 90 4.3 0.5 1 20 120 139 120 141 0.89

2 26 0.77 50 5.1 2.2 3 23 147 166 146 166 0.98

3 26 0.00058 0.037 14.9 0.2 1 23 171 193 171 193 0.98

4 26 0.058 3.8 8.6 1.0 3 23 199 220 198 220 0.93

5 26 0.027 1.8 9.7 2.0 2 21 224 243 223 244 0.92

6 26 0.19 12 7.0 1.4 1 23 253 276 253 276 0.94

7 26 0.00041 0.027 15.4 5.5 1 23 282 304 282 304 0.98

8 26 6.6e-07 4.3e-05 24.2 1.0 1 23 311 334 311 334 0.97

9 26 0.42 27 5.9 0.2 2 19 451 468 450 471 0.76

10 26 2.6 1.7e+02 3.4 1.1 3 23 477 497 476 497 0.91

11 26 0.013 0.85 10.7 2.8 1 19 530 548 530 552 0.91

12 26 0.7 45 5.2 5.1 1 20 555 574 555 576 0.92

13 26 0.0014 0.09 13.7 0.2 1 23 588 611 588 611 0.93

14 26 0.00011 0.0069 17.2 1.8 1 23 617 639 617 639 0.98

15 26 0.025 1.6 9.8 3.0 1 23 673 696 673 696 0.96

16 26 0.0025 0.16 12.9 0.5 3 23 706 727 705 727 0.96

17 26 0.00012 0.0078 17.1 0.1 2 21 834 853 833 854 0.94

18 26 0.036 2.3 9.3 0.1 2 23 860 882 859 882 0.94

19 26 2 1.3e+02 3.8 0.5 3 23 889 910 888 910 0.96

20 26 0.0015 0.099 13.6 0.4 2 23 916 937 915 937 0.96

21 26 0.012 0.79 10.8 2.0 2 20 941 959 940 961 0.92

22 26 7.7e-06 0.0005 20.8 1.1 1 23 987 1010 987 1010 0.95

23 26 6.8e-05 0.0044 17.9 0.3 1 23 1016 1038 1016 1038 0.96

24 26 0.046 3 9.0 0.2 1 23 1044 1066 1044 1066 0.98

25 26 0.015 0.95 10.5 0.1 1 23 1072 1095 1072 1095 0.94

26 26 0.00013 0.0083 17.0 0.5 1 23 1101 1124 1101 1124 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	26	1.4	90	4.3	0.5	1	20	120	139	120	141	0.89
2	26	0.77	50	5.1	2.2	3	23	147	166	146	166	0.98
3	26	0.00058	0.037	14.9	0.2	1	23	171	193	171	193	0.98
4	26	0.058	3.8	8.6	1.0	3	23	199	220	198	220	0.93
5	26	0.027	1.8	9.7	2.0	2	21	224	243	223	244	0.92
6	26	0.19	12	7.0	1.4	1	23	253	276	253	276	0.94
7	26	0.00041	0.027	15.4	5.5	1	23	282	304	282	304	0.98
8	26	6.6e-07	4.3e-05	24.2	1.0	1	23	311	334	311	334	0.97
9	26	0.42	27	5.9	0.2	2	19	451	468	450	471	0.76
10	26	2.6	1.7e+02	3.4	1.1	3	23	477	497	476	497	0.91
11	26	0.013	0.85	10.7	2.8	1	19	530	548	530	552	0.91
12	26	0.7	45	5.2	5.1	1	20	555	574	555	576	0.92
13	26	0.0014	0.09	13.7	0.2	1	23	588	611	588	611	0.93
14	26	0.00011	0.0069	17.2	1.8	1	23	617	639	617	639	0.98
15	26	0.025	1.6	9.8	3.0	1	23	673	696	673	696	0.96
16	26	0.0025	0.16	12.9	0.5	3	23	706	727	705	727	0.96
17	26	0.00012	0.0078	17.1	0.1	2	21	834	853	833	854	0.94
18	26	0.036	2.3	9.3	0.1	2	23	860	882	859	882	0.94
19	26	2	1.3e+02	3.8	0.5	3	23	889	910	888	910	0.96
20	26	0.0015	0.099	13.6	0.4	2	23	916	937	915	937	0.96
21	26	0.012	0.79	10.8	2.0	2	20	941	959	940	961	0.92
22	26	7.7e-06	0.0005	20.8	1.1	1	23	987	1010	987	1010	0.95
23	26	6.8e-05	0.0044	17.9	0.3	1	23	1016	1038	1016	1038	0.96
24	26	0.046	3	9.0	0.2	1	23	1044	1066	1044	1066	0.98
25	26	0.015	0.95	10.5	0.1	1	23	1072	1095	1072	1095	0.94
26	26	0.00013	0.0083	17.0	0.5	1	23	1101	1124	1101	1124	0.96

Sequence Information

Coding Sequence: ATGGAGGAAACTCAGAAAACGACGCCGCAGCAAGTATGCCATCGGTGTATCTCGCACGTCACTACCTTTCTGCCTTTCCTGAAGCTGTGCAAGCAATCAGCTGCGCACTGGACCTATGTATCCGAACGACTAATCGACATTTCCGGCAATGCGAAAGCCACTACGGCATTTATCTTCATCACCGAAAACCACGTCCGAACCGTGGTAGAACGTAGggataaaagaaaaaatcttAACTTGAAAAACGTAAAAATGCGCATTAATCGAATTGAGAAGGAAACGAAAAAGAGTCTAGAAACGTTTAGACAACCCGAGTCATTAGAGGAACTTAAGCGTGGACAATGGAAAGCGGAACTGTATACATGCCAAGAGTGTGGGTCAGAATATAAAAAGCTATGCGAGATCAATCTCCACTTAGCTAACCGAAACAAACGACTTTGCAAACACTGTTACAAAGTAGTGGACCTAAAATCTTTTTGGGAGCACCTGAAAACGCACGCGTTCCTTTACTTCAAATGTGAAATTTGCTCGCTGCCTTTTGAGTATGAAGTGCAGTTAGAAAAACACAAGAATGTTCATAAAGGAAGGAATATGTGCGAGGAATGCAAAAGAACCTTTCCTACAGCGGATATTTTGACGTTACACGTCCACAAGAGACATCAGCCAGATGTCTGTAACGCCTGCGACAAAAAATTCTCTAATAGGATATGCCTGTACAAGCACAGAAGTAAATGCAAATCAAAATCACCGAAACTCTATGTCTGCGATTATTGCTGCAAAGAATTTAACGATCGAAGCGTGATAAAGTCCCACATAACATTAGTTCATTCAAAGAAATTGATGCATCAGTGTGAACAGTGCGGTAAACAATTCAACAGCGCTTGTCATTTGGAAGAACATTATGAGACGCACGAAGTTATACTAGACAGATTTGTCTGCCAATACTGTGGCAAAATATTCAGTTCTTCAGGAGGTTACCGACGACATATGAGATTAAAGCATTACAACGTGAATCCGGAGCTGAAGAGGGAGGCAAAGTACTCGTGTGAGGTCGATGAAGATCCCATCCTCCCGCCGGGCCTCTGCCGCGTCTGTGCAGAAGACGTCGTTACCGCCGCCAAATTCAAGCATCTAAGTGAAAAGTCCGCTCAAAGCTGGAGCGAGGCCGCCTCTTACCTCATCGAAACGAACCTTGAAAGCGAAGACAAAACCTTATTCTATTTGTGTGAGGAAAAAGACATGATTATTTGCGAACAGAGAGTTGACACTGTTAAATCCGCTGTGACCACTCTAGGGTAtttaaaaattactgaaaagcAGAAGAAAGCTAAACGAAAAGAATCCGCTTGCGCTTGCCCTTATTGCGATAAACAATTCGCTGCTCTAGATATCCTAAACGATCACCTGACGAACGCGCAGAAGAGGGTGTGTTGCGAATGCGGTCGGATCATGGGCAAGTCTGAGTTGTCTAAGCACTTGCGCGATACGCACGGAATAAATATAATGGAGTGTAAGATTTGCTTCGACCAGCTCAGTAGTTATGGCGACTCGAATTGGCATATGATGCGATATCACGGCCCGAAGTCGTTCACGTGTAAAAACTGCGGACGCGGTTACAGAAACGAGAGAGGATTGCGAGCGCATTGCTATTCCCATTCGCTGTTCTGTTGCGCGGCTTGCGGTCGAAGCTTCGAGAACAATCGCTGCTACCGCCATCACAGAACCATATGCAAGTCTAAGCAGAAGGCCGAGTTCGGTATTTACGAATGCAACGACTGCGGGCTGCAGTACGATAAGAAACCTTCCCTTAAAATACATATAGTACAGAAACACTTGAACGTTCTGCCGTTCGTTTGTCAAACATGCGGTAAACGTACCTCGACTCTAGCACATTTAAGATCACACGAAAAAGTCCACGATGATAACAGAAAGACGTTTGAGTGTCATTGCGGTGCGAAGTTTCGGACTGAGTTAGGACATCGTCTGCATATGAGGATGCACAGTGGTTTGAAACCGTACAAATGCTCTCACTGCGAGGAATCTTTTATATCAGCGTCCAGACGTTTGGATCACACGAAAAGGAGGCATAAAAGTGCGGAAGAAATGGCGCATGGATGCGATCTCTGCCCCGCTCGGTTCATAAGACCTTGGGAACTGAAGAAGCATTATAAACATTTACACAGCTCTGTGATACTAGAGGAGAGTGCGTGTCCGGGCGGCGTCTGCGCTGCGTGCGCGCAGGCGGCGCTCGGCGCGGCGGAGTTCCGACTGCTCGTGAGAGCCGCGCGGACGCTGTGGCTGCGCGCCGTCCACTCCCTCGCAAAACTGCCGCAACACAGAGGCCACCCGCACAAGTCCCTCTGCGCCTTCCTCTCTCACCACGACGCCTCGCTCGAGATCCTGAGCGAGTTCGACGGCGAACCGGGCTCCCTCCTCGACCGGCCCGTCCCGAAGAAATACGAGCGGAAGCCGCGGATCCCCCGCAACGGTCCGCTGACCTCCTGCCCGGACTGCGGCAAGCGCTTCGGGAGCCCGCAACTCCTGCAGGTACATCTGCAGAACAGCGATCGGAAGGACGTCTGCCGGTTGTGCGGGCATGTGTTCCCGCGAGGCGTCGAGATGAAGAACCATCTGGAGATAGCTCATAACGAAACTCCGGTGCTGTGCAAGGAGTGTCCGACCGTGCACGCATCGGAGGACGAATTCAAGATTCACGAGAAGAAAGCGCACAGATCCGGCGCGAAGACTTGCAGCGCTTGCGGTCGCACCTTCACCAGACTCAACGCTTACGAGAACCACGTCGAGATGCACGTGGTGCTTTCATGCCGTAGCTGCGGAAAGCAGTTCTCCAATCGGAGCTGCTACCGGGTGCACAGGGCTAGCTGCGAGCCGGATGCGAAGCCCCATCCGAACACGGTGCCGCGCGGCCGGCGGTCCAACGTCCGAGACCCCGGCCGCTTCGTCTGCGACCACTGTAACAAGAGTTACAGCTCGCGCCCGCAACTGAAGAACCACATCCTCTGGATCCACATGGACCACCGTCCCTACCAGTGCTCTTGGTGCGGTAAACGGTTCTATACTCCGGCGAGGTTGAACGAACACACCGTTGTGCACACTCGAGTGCGAAATTTCGAGTGTGATTTGTGCGACGCGAAACTGGTGTCCAAGAGTGCTGCTATCTACCACAGGAGACGGCATACTGGCGAGAAACCGTACGTTTGCGACGATTGCGGGGCCGCCTTCATATCCTCGTCGCGGAGACTGGAACACGCTAAGAGGAAACATAATAAGGGAGTCAAGTTTGAATGTTCGGAGTGCCCGGCCAGGTTTGTTCGAAGACGGGAACTGGAGAAACACACTGAAAAGAATCATAAGCAAATCACGGTTCATTTTCCGACGTCGACGTGTGACCAATTGGAGAGTAAAATCATTTGA
Protein Sequence: MEETQKTTPQQVCHRCISHVTTFLPFLKLCKQSAAHWTYVSERLIDISGNAKATTAFIFITENHVRTVVERRDKRKNLNLKNVKMRINRIEKETKKSLETFRQPESLEELKRGQWKAELYTCQECGSEYKKLCEINLHLANRNKRLCKHCYKVVDLKSFWEHLKTHAFLYFKCEICSLPFEYEVQLEKHKNVHKGRNMCEECKRTFPTADILTLHVHKRHQPDVCNACDKKFSNRICLYKHRSKCKSKSPKLYVCDYCCKEFNDRSVIKSHITLVHSKKLMHQCEQCGKQFNSACHLEEHYETHEVILDRFVCQYCGKIFSSSGGYRRHMRLKHYNVNPELKREAKYSCEVDEDPILPPGLCRVCAEDVVTAAKFKHLSEKSAQSWSEAASYLIETNLESEDKTLFYLCEEKDMIICEQRVDTVKSAVTTLGYLKITEKQKKAKRKESACACPYCDKQFAALDILNDHLTNAQKRVCCECGRIMGKSELSKHLRDTHGINIMECKICFDQLSSYGDSNWHMMRYHGPKSFTCKNCGRGYRNERGLRAHCYSHSLFCCAACGRSFENNRCYRHHRTICKSKQKAEFGIYECNDCGLQYDKKPSLKIHIVQKHLNVLPFVCQTCGKRTSTLAHLRSHEKVHDDNRKTFECHCGAKFRTELGHRLHMRMHSGLKPYKCSHCEESFISASRRLDHTKRRHKSAEEMAHGCDLCPARFIRPWELKKHYKHLHSSVILEESACPGGVCAACAQAALGAAEFRLLVRAARTLWLRAVHSLAKLPQHRGHPHKSLCAFLSHHDASLEILSEFDGEPGSLLDRPVPKKYERKPRIPRNGPLTSCPDCGKRFGSPQLLQVHLQNSDRKDVCRLCGHVFPRGVEMKNHLEIAHNETPVLCKECPTVHASEDEFKIHEKKAHRSGAKTCSACGRTFTRLNAYENHVEMHVVLSCRSCGKQFSNRSCYRVHRASCEPDAKPHPNTVPRGRRSNVRDPGRFVCDHCNKSYSSRPQLKNHILWIHMDHRPYQCSWCGKRFYTPARLNEHTVVHTRVRNFECDLCDAKLVSKSAAIYHRRRHTGEKPYVCDDCGAAFISSSRRLEHAKRKHNKGVKFECSECPARFVRRRELEKHTEKNHKQITVHFPTSTCDQLESKII

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01171651;
90% Identity: iTF_01171651;
80% Identity: -