Pfla006674.3


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Perizoma flavofasciatum
Gene Symbol
Rfx2
Assembly
GCA_958496245.1
Location
OY292426.1:1838989-1862902[-]

Transcription Factor Domain

TF Family
RFX
Domain
RFX domain
PFAM
PF02257
TF Group
Basic Domians group
Description
RFX is a regulatory factor which binds to the X box of MHC class II genes and is essential for their expression. The DNA-binding domain of RFX is the central domain of the protein and binds ssDNA as either a monomer or homodimer [1]. It recognize X-boxes (DNA of the sequence 5'-GTNRCC(0-3N)RGYAAC-3', where N is any nucleotide, R is a purine and Y is a pyrimidine) using a highly conserved 76-residue DNA-binding domain (DBD) [2].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 1.7e-36 8.1e-33 113.3 0.0 3 78 203 278 201 279 0.97
2 2 2.1 1e+04 -2.4 0.0 24 42 1195 1214 1184 1217 0.79

Sequence Information

Coding Sequence
ATGTCCGAGATGGGGTTTGAAAATGTGTTCTACCTAGAGAATTTCGAGTGTGCCGGTGACGAGGTTCTGGTGGAGTCTTCGCCGCCCGCCTCTCCCGACATGGCGGCGCGGTTAGCGGCGCCCGCGCAGGGTAATGGCGCGGGCGGTGCGTCCCCCAGCGCAGTCCGTGACCTGATCGTGATTCCCGAGCTGCCGGATTCCATACATCTGCAGCACGCCATGCAGCAGGTGTCCAGCTCGGTGGTGGAAGTGAACGGCGTGAACGGCGACAGTTCGGGACAATCAAGCCCGAATGCCGAGCCTCAACACACCTTCATCACAGTCGCAAGCGAGGGAGGGAATGGAGTCAATTACCACGTGCAGTATGTCACCGAGCCGCAGGAGATATACGCGCAAGGACATCAGCCTATGGAGACGCTCCGCTCGTACCCGGTGTACGGCGTGGCGACGGTCGCGAACGGAGGCGGCGACACAGAGGCCGCGTGGGGCGGGGCCACCTCCGCCGACTACACCGCCTATGGCGTCGTGGTGGCAGGCGACGAGGCGTCTGCGCCGGCGTCCCCCGCCACGCCGGCCGGCGCCCCGCAGCCGCCGCGCATGCCGCCCGCCACCGTGCAGTGGCTGCTCGACCACTACGAGACCGCTGAAGGCGTATCCCTCCCGCGTTCGACTCTCTACGCGCACTATTTGCGGCACTGCTCGATTCACCACCTCGAGCCGGTGAACGCGGCGTCGTTCGGGAAGCTGATCCGCTCGGTGTTTGTGGGGCTGCGGACGAGACGGCTCGGGACGAGGGGGAACTCGAAGTATCATTACTATGGGATCCGCGCCAAGCCCAATTCAGACCAGCACGCGCCCGACGCGAACGACAGCGCCGATGACAACGCCGAGCTCAATGAAAAGGAGCGCGATCGTTCCCGCGAGCGCGAGGAAGGTCCGGGCTCGCCGCTCGGCGCCGCCTCCGTCGCCAACCGGCAGTACCTCGCGTCCGTCACGGCGCCGTCGCCGCCCGCGCTCGATCTACCGATGTCGGACGACATCCCGCCCGGCGCCTTGCAGCTGTTGCGACGACATCACCGTACCTCGCGTCCGTCACGGCGCCGTCGCCGCCCGCGCTCGATCTACCGATGTCGGACGACATCCCGCCCGGCGCCTTGCAGCTGTTGCGACGACATCACCGGTAATATACTCGCTTATTATGCACAGTACCTCGCGTCCGTCACGGCGCCGTCGCCGCCCGCGCTCGATCTACCGATGTCGGACGACATCCCGCCCGGCGCCTTGCAGCTGTTGCGACGACATCACCGCGAGCACGGCGCCATGTTCCTGGAGGCGGTGGCTGCGCTGGACACGGGCGCCGTGGAGGCCGCGCGTCGCGCCTTCTGGAGACGCAGCTCCCCTGAAGACAACACCCTGTGCCGACGCACGCTGGCAAGACTCTGCTCAAGGAAAGACGTCTGTCGCTGGCTTCGATCGGCCGATACGCAGCTGTACCAACGCGCCGTGGATATGCTACTGCCTGATGTATTGCGTCCGATACCACCACAACTCACACAGGCAATCCGCAATTTCGCTAAGAGTGTGGAATGCGCCGTGTCGGCCGGGTCGGGCGGAGCGCCTCTGCCGGCTGTGCGTGCGCAGGCTCGGGCCGCAGCCGCTCTAGCCGGGGCGCTGCGCCGCTACACCTCGCTCAACCACCTCGCGCAGGCGGCGCGAGCCGTGCTCACCAACCACCACCAGATACACCAGCCGGGGCACTGCGCCGCTACACCTCGCTCAACCACCTCGCGCAGGCGGCGCGAGCCGTGCTCACCAACCAACACCAGATACACCAGGTATGCGCCCGCTCTAGCCGGGGCACTGCGCCGCTACACCTCGCTCAACCACCTCGCGCAGGCGGCGCGAGCCGTGCTCACCAACCACCACCAGATACACCAGCCGGGGCACTGCGCCGCTACACCTCGCTCAACCACCTCGCGCAGGCGGCGCGAGCCGTGCTCACCAACCACCACCAGATACACCAGGTATGCGCCCGCTCTAGCCGGGGCACTGCGCCGCTACACCTCGCTCAACCACCTCGCGCAGGCGGCGCGAGCCGTGCTCACCAACCACCACCAGATACACCAGCCGGGGCACTGCGCCGCTACACCTCGCTCAACCACCTCGCGCAGGCGGCGCGAGCCGTGCTCACCAACCACCACCAGATACACCAGGTATGCGCCCGCTCTAGCCGGGGCACTGCGCCGCTACACCTCGCTCAACCACCTCGCGCAGGCGGCGCGAGCCGTGCTCACCAACCACCACCAGATACACCAGCCGGGGCACTGCGCCGCTACACCTCGCTCAACCACCTCGCGCAGGCGGCGCGAGCCGTGCTCACCAACCACTACCAGATACACCAGGTATGCGCCCGCTCTAGCCGGGGCACTGCGCCGCTACACCTCGCTCAACCACCTCGCGCAGGCGGCGCGAGCCGTGCTCACCAACCACCACCAGATACACCAGCCGGGGCACTGCGCCGCTACACCTCGCTCAACCACCTCGCGCAGGCGGCGCGAGCCGTGCTCACCAACCAACACCAGATACACCAGGTATGCGCCCGCTCTAGCCGGGGCACTGCGCCGCTACACCTCGCTCAACCACCTCGCGCAGGCGGCGCGAGCCGTGCTCACCAACCACCACCAGATACACCAGCCGGGGCACTGCGCCGCTACACCTCGCTCAACCACCTCGCGCAGGCGGCGCGAGCCGTGCTCACCAACCACCACCAGATACACCAGGTATGCGCCCGCTCTAGCCGGGGCACTGCGCCGCTACACCTCGCTCAACCACCTCGCGCAGGCGGCGCGAGCCGTGCTCACCAACCACTACCAGATACACCAGCCGGGGCACTGCGCCGCTACACCTCGCTCAACCACCTCGCGCAGGCGGCGCGAGCCGTGCTCACCAACCACCACCAGATACACCAGGTATGCGCCCGCTCTAGCCGGGGCACTGCGCCGCTACACCTCGCTCAACCACCTCGCGCAGGCGGCGCGAGCCGTGCTCACCAACCACCACCAGATACACCAGCCGGGGCACTGCGCCGCTACACCTCGCTCAACCACCTCGCGCAGGCGGCGCGAGCCGTGCTCACCAACCACCACCAGATACACCAGGTATGCGCCCGCTCTAGCCGGGGCACTGCGCCGCTACACCTCGCTCAACCACCTCGCGCAGGCGGCGCGAGCCGTGCTCACCAACCACCACCAGATACACCAGATGGTGTCGGACCTGAACCGCGTGGACTTCCGCGTGGTTCGCGAGCAAGCTTCCTGGGCCTGCGCCTGTCCCTCCGCCGCCGTGGCGCTCAAGCTCGAAGCAGACTTCAAGGCGACGCTGAGCCGCGGCGCTACGCTGGAGCAGTGGGCGGGCTGGCTGGAGCGCTGCGTGAGCGGAGCGCTGGCGCCGCACGAGGGCCGCGCCGACTACGTGCCGCGCGCGCGCCGCCTGCTGCTCGACTGGTCCTTCTACTCCTCCCTCGTCATCCGCGAACTCACACTCAGATCTGCGGCTTCGTTCGGCTCGTTCCACCTGATCCGGCTTCTGTACGACGAGTACGTGTCCTACCTGATCGAGCGACGCGTCGCGACGCATCTCAACGCGCCGCCCATCGCCGTCATGCATCGCACGCAGgaggaagaagaagaagaaggtcAAGAAGAGAACCGCGTCGAGGGTCTGGAAGAAGATCAAGACTGGGACTGGGAGGacgaggaagaggaagaggaaccGGAGAGCAAGAAATCGAAGACCGGCTGTGAGTAG
Protein Sequence
MSEMGFENVFYLENFECAGDEVLVESSPPASPDMAARLAAPAQGNGAGGASPSAVRDLIVIPELPDSIHLQHAMQQVSSSVVEVNGVNGDSSGQSSPNAEPQHTFITVASEGGNGVNYHVQYVTEPQEIYAQGHQPMETLRSYPVYGVATVANGGGDTEAAWGGATSADYTAYGVVVAGDEASAPASPATPAGAPQPPRMPPATVQWLLDHYETAEGVSLPRSTLYAHYLRHCSIHHLEPVNAASFGKLIRSVFVGLRTRRLGTRGNSKYHYYGIRAKPNSDQHAPDANDSADDNAELNEKERDRSREREEGPGSPLGAASVANRQYLASVTAPSPPALDLPMSDDIPPGALQLLRRHHRTSRPSRRRRRPRSIYRCRTTSRPAPCSCCDDITGNILAYYAQYLASVTAPSPPALDLPMSDDIPPGALQLLRRHHREHGAMFLEAVAALDTGAVEAARRAFWRRSSPEDNTLCRRTLARLCSRKDVCRWLRSADTQLYQRAVDMLLPDVLRPIPPQLTQAIRNFAKSVECAVSAGSGGAPLPAVRAQARAAAALAGALRRYTSLNHLAQAARAVLTNHHQIHQPGHCAATPRSTTSRRRREPCSPTNTRYTRYAPALAGALRRYTSLNHLAQAARAVLTNHHQIHQPGHCAATPRSTTSRRRREPCSPTTTRYTRYAPALAGALRRYTSLNHLAQAARAVLTNHHQIHQPGHCAATPRSTTSRRRREPCSPTTTRYTRYAPALAGALRRYTSLNHLAQAARAVLTNHHQIHQPGHCAATPRSTTSRRRREPCSPTTTRYTRYAPALAGALRRYTSLNHLAQAARAVLTNHHQIHQPGHCAATPRSTTSRRRREPCSPTNTRYTRYAPALAGALRRYTSLNHLAQAARAVLTNHHQIHQPGHCAATPRSTTSRRRREPCSPTTTRYTRYAPALAGALRRYTSLNHLAQAARAVLTNHYQIHQPGHCAATPRSTTSRRRREPCSPTTTRYTRYAPALAGALRRYTSLNHLAQAARAVLTNHHQIHQPGHCAATPRSTTSRRRREPCSPTTTRYTRYAPALAGALRRYTSLNHLAQAARAVLTNHHQIHQMVSDLNRVDFRVVREQASWACACPSAAVALKLEADFKATLSRGATLEQWAGWLERCVSGALAPHEGRADYVPRARRLLLDWSFYSSLVIRELTLRSAASFGSFHLIRLLYDEYVSYLIERRVATHLNAPPIAVMHRTQEEEEEEGQEENRVEGLEEDQDWDWEDEEEEEEPESKKSKTGCE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-