Pace000546.1
Basic Information
- Insect
- Periphyllus acericola
- Gene Symbol
- -
- Assembly
- GCA_949715065.1
- Location
- OX454264.1:6001430-6012508[+]
Transcription Factor Domain
- TF Family
- MBD
- Domain
- MBD domain
- PFAM
- PF01429
- TF Group
- Unclassified Structure
- Description
- The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 4.2e-11 5.1e-08 33.0 0.1 9 71 126 195 121 198 0.85 2 2 0.56 6.8e+02 0.5 0.0 29 67 322 359 312 368 0.71
Sequence Information
- Coding Sequence
- ATGTCGTATGCTGAAGCTGCACAAAAGAAATCTGATGAACTATTAAAAACAgaagaacattttattggatTTGATATAAATGATGAAGTATCAacccatttaaaaaataaaatacgatgtATAAAACAAGTAATTTGTGAAATAGAAGAGATGGGAGAGGATGAAGAAGAAACAAATGATACAAAACACAATCGAAGTTctaataaaagaattaaaaaaaataatgtacgcaCTGAAGCAATAGAATCTTTGAAATCCAATGCTCCGCCAAGTTTGAaacttacATCTCCAACATTCAACCTCACTTTAACATCTAAATCTCGTCGTAGTGCTGGACAAAAACTGAATGTTGATATTAGCgatcaaatttttaaacttccTTTTGAACGTGgatGGAAACGAGAATTAGTATATAGAACTACTAGTGATTTTTCATCTATGAATCAGGCTAATAGAAACagtgatgtatattattattctccaAATAATCGAAAGCTTCGGtcattaaaagaaattcaagAACAATTGGATTTATCACCGACTGAAGAAAACCCATTAACCATAgaaagttttacatttataaaacaaccTATTGGCATTAATGACCGATCAAAAGAATTAATAAGAGAAGCAAAAACTAAATTatctaaaGTATATCCATTTGTTCCTGTTACCGATCGACCAAAGAAAGTAAAAACACCTGTACGGCCTTTTGATTATGAATTGCcagataatgagaataaaaagtctgcaagcaaaatgaaaattgtttttaaaaaagctaagatgtctaaatcaaaatcaaaaaaagataaaaCTAATTCAGAGGTGCCTTCATCTATACCAGAATATATAGCTGAAGATTTGCAAGCTATTCAATCTAGTGTAACACCTAAAACGTCGTCACCAAAAGCTGATGATGTTGAAATAAATGTTGCACTTACTAAAAGAcgGTTGTCAACATCAGATGGGGAAGTTGTCATGCAGACCCCATGTGGAATACGTTGTCCCAACAGCGATGAACCAGCCACATTGATGTGTTCTCAATGCCTGGTCTACTATCATCCGGCCTGTGTCAATTTAAATGCTAGTCTAAAAATTGTTGGTTATGTATGCATAAATTGTCGATCTGATATGTGTCTAAAAAATAGGCAAGTAGAGCTATCTCATACTGTTGTCGTTGGTACTCCTGAACCAGAACAGTTACGAGTTGAACCAATTCGTATACGTCAAGTTCATCAAGCATCAGACacacctaattttattattgatagaaCATCTTTTATCAATTCTGAAGAATCCAATTCTGAAAGCGATGATCATAGTGAAGAAAATAACACTGTTTTAAATATGGTAACATGTCAAGGAAATGTCATTGAAACCTCTATGGTCGATGGAAACTTTCacgaacaatatgtatatgaaatgaAACAAACACGAGGACCTAGTTTGATGACCTGTGTTGTTCAAGAGCCTAAGTATTTGGATGAaaatccTGTAGTGAATGGTTCACTTAAGGAAAGCCCTGCTCAAATGACATATATGGAATCATTTAATTACATGGTAAAAGCACTGAGACATGTTTTCAGTTATTTAAAAGTGCAAGAACTTTTATCAGCTTCCCGGGTGTGTATTGCTTGGCATATAATTGCAATGGATAGACTTttatgGCAAAATGTTCGTTTAAAGAATTCTATGGTTTATGACTGGAATAAATGTGttgatacaattaataaacaagGTACAGTTTCATTGGACTCTAGGCGTATGTTAATGCCTACTAATGTTGAAGAATTCGAAAATGTTTGGTTTCGTTTTTCTGTGGCAATGAAAGAAGCAACAAAATTAAAGGCAATTGAATTATATAGATGTCCCACTCATGTAGttgaagatataatttattcattacctCAACTTAGTGTTCTTAATGCTTCTTCATTAAAaaatccaAATTCACCTAAAGATTCAAAAAGTCCTAATGAATATATGACtttaaatttggaatatttAGGACAATTGACAAACCTTACTGAGCTAAAGCTTAAAGGTCCAATTGGAATTAAGTTGTCAAAACTTCCATCATttgataaattagtaaatttaaaaacgttgtcaTTAACCTCCATTAAAGCATTACCAAATAATTGGTTTAGTAGTTTGGAATCTATTACAACAGgtttagagtttttggagaTTGGTGACTGTGACAGCTTATCAAAAGATTTTGCTAGGGTACTACAGAGATTAATCAATTTAACTTCCTTGAGATTAGAAAGTTGTGTTGGTATATGGGAATATTTTGCTGAAGATGTTTTTATTGTGATTAGAAATCTTGAAAAACTCAGGGTTTTGGAATTGATAAATATAGACTTCAGTTATAGCATTGAAGACGAATTGGAGAAGTGTTTGGGCATTAAAGCTTTACTGATCATTCCTACTTATATTACCCAAtctGCAACTACCAACTGTCACCTTATTGACTGTCTCAAAAAACTCTCTAAAACTTTAACCCATCTTGTTTGGGGAATAACACATGAATTGCTCCATGTGACAGACTTATTTCTTTCTCAATATGATCAAACTATTGGCTACGCTTTAGAATTATCATGCACAAGAGAACGTGCCAATAACATACCTATACTGAGGAATAGGAATCCCAGACTACGTCCCGGAGAAGAACCTATTCCCGAAAAAGAGAATGATAAAGGAAAATCAGATAACGTTGATATACTTTCTGTTCCAGCTCTTCAGAGATTATTAGAAACCATGATGATTGGTGCTAATATTAAAGTTCTTAAAATTCCTTTTTCAGGGACGACTCAAGTTTATTTAGCTGATCAGTTTAATGATCTTAAAAGATCAATTTAG
- Protein Sequence
- MSYAEAAQKKSDELLKTEEHFIGFDINDEVSTHLKNKIRCIKQVICEIEEMGEDEEETNDTKHNRSSNKRIKKNNVRTEAIESLKSNAPPSLKLTSPTFNLTLTSKSRRSAGQKLNVDISDQIFKLPFERGWKRELVYRTTSDFSSMNQANRNSDVYYYSPNNRKLRSLKEIQEQLDLSPTEENPLTIESFTFIKQPIGINDRSKELIREAKTKLSKVYPFVPVTDRPKKVKTPVRPFDYELPDNENKKSASKMKIVFKKAKMSKSKSKKDKTNSEVPSSIPEYIAEDLQAIQSSVTPKTSSPKADDVEINVALTKRRLSTSDGEVVMQTPCGIRCPNSDEPATLMCSQCLVYYHPACVNLNASLKIVGYVCINCRSDMCLKNRQVELSHTVVVGTPEPEQLRVEPIRIRQVHQASDTPNFIIDRTSFINSEESNSESDDHSEENNTVLNMVTCQGNVIETSMVDGNFHEQYVYEMKQTRGPSLMTCVVQEPKYLDENPVVNGSLKESPAQMTYMESFNYMVKALRHVFSYLKVQELLSASRVCIAWHIIAMDRLLWQNVRLKNSMVYDWNKCVDTINKQGTVSLDSRRMLMPTNVEEFENVWFRFSVAMKEATKLKAIELYRCPTHVVEDIIYSLPQLSVLNASSLKNPNSPKDSKSPNEYMTLNLEYLGQLTNLTELKLKGPIGIKLSKLPSFDKLVNLKTLSLTSIKALPNNWFSSLESITTGLEFLEIGDCDSLSKDFARVLQRLINLTSLRLESCVGIWEYFAEDVFIVIRNLEKLRVLELINIDFSYSIEDELEKCLGIKALLIIPTYITQSATTNCHLIDCLKKLSKTLTHLVWGITHELLHVTDLFLSQYDQTIGYALELSCTRERANNIPILRNRNPRLRPGEEPIPEKENDKGKSDNVDILSVPALQRLLETMMIGANIKVLKIPFSGTTQVYLADQFNDLKRSI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01169853;
- 90% Identity
- iTF_01169847;
- 80% Identity
- -