Phum004426.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Pediculus humanus
Gene Symbol
-
Assembly
GCA_000006295.1
Location
NW:2887-6667[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 2.4 1.6e+02 2.4 2.8 1 10 201 210 201 210 0.95
2 11 2.7e-07 1.8e-05 24.2 0.5 1 23 245 267 245 267 0.98
3 11 1.5e-08 1e-06 28.1 1.8 1 23 273 295 273 295 0.98
4 11 6.3e-05 0.0042 16.8 5.4 1 21 301 321 301 323 0.95
5 11 0.0012 0.078 12.8 2.5 1 23 355 378 355 378 0.97
6 11 8.6e-05 0.0058 16.3 11.5 1 23 391 413 391 413 0.98
7 11 4.1e-05 0.0027 17.4 5.3 2 23 654 676 654 676 0.97
8 11 8.5e-06 0.00057 19.5 6.7 1 23 722 745 722 745 0.97
9 11 0.046 3.1 7.7 2.0 2 23 762 783 761 783 0.94
10 11 0.046 3 7.8 3.0 1 21 807 827 807 828 0.94
11 11 2.7e-06 0.00018 21.0 1.8 1 23 831 853 831 853 0.99

Sequence Information

Coding Sequence
atggAAGAATCAAAGCTTATTATCGATGAAGAATTGTGTCGCATTTGTAGAAGTACGGAAGGGGGTCAGCTTGATATTTTTGGGCTCTCTGGGGCGGAACGAAATATTTCTACAAAAATTCGTGAATGCCTACCCATAAAAGTGTCAGAAAAAGATGGCCTCCCGAAAACAATTTGTGCGGAATGCGCGGAAAAactcgatgatttttttaattttcgtaatATGTGTAGGAAAATCGATTCGACGTTTAACGAATTGCTTCattccgataataataaatccgatTCCGATGATTGTTCTAATTCGAAAACATCGGAAACTTCTAAAGACAAAGTCGATAGCAGTTCAACTCAATTATCGATTGAAATACAAAGTTCCAGCTCACCAAAGAAAAAACAAGCTAATTTAGGAGATCCTCAGCCTGAAGATTATGTTTTGATGAAAGAGGAAACTATAACTGTTGACAATACTACTAAAATAAatcaagaagaaaaacaagttGATCCGAAAGGAGCAAAGGGTAAACAACAAAATACTAGAACTGTACtcaagggaaaattttctgtGATTCACAGAAGGTACATTGTTGCAAAAGGAGCATTTCCTTGCTCCCTGTGCGGTcggtgttttttatttaatcaaggTCGTCCACGAGAAGGTATTCCTTATGCGGATGCTGATATCGTACAGGGAGATCAAGATAGCAATACCGATAGTCCTTCTGACGGTTTGTATCCGTGTCCTCAATGTGGTAAACTCTTTCCTCGAAGAACGAGTTTAAAACGTCATCAACAAATACATtttgaagggaaaaaatttgtgtgtAAAGTATGTGGGAAAGCATTCAATAGAAATGAGCATTTAACAAGACACATGTTATCTCATACCGGAGGCCGACCTTTCCAATGCGATCTATGCTCTAAAGTTTTCACTCGAAAGGAACATCTCGTTAGGCACAGGCAATGTCACGACGTGAGCGGAGTCGTGATCAAAGAAGAGCCGGATGATTCCGTCAACAGCTATGGATTTTCAGATTTTGCAGACGCTACGGAAACTAAACCTTTCGTTTGCGACATTTGTCACTCTGCCTACGCTCGACGTGAACACAtgacaaaacataaaaaagttGCTCACGGGATCGATGCCGATCCTGAATCCGAACCTAAACCCTATTGCTGCAACCATTGTTTTAAGACTTTTACGCGTAAAGAACATCTCACACGCCACAAAAAAATACACATTCGAGAAGCATTTTCTGGTAATTATGAAATTGCCGACGGTGTGGCACCTTCATTACTTATTTCCGGTCCCACAGGTAGCAAGTTACAAAAAGATAAGTCGAAAAAAGACGTTTTAATTCCACTCACTGTAAATTGTAATAtcagtaaattaaataatgtgaCCATTACTCCACAACCTAAGGGAACCACCATTCTTAAAAATCCAATAACAAAACCTCAGGTTAGCGTTGTCAAACCTATGACAAACGTCACACCGTTAAGTATAAATAAAGATACCGTAACGTTAGAGATATCCGGTGGAAGTGACGGAGGAGAGTATAAATCAAAAGTTGGCGAAACTTTAATGAAtagtatattaaaaaatggaaaatatggCGAAATCAGCATTGTCGAtgttaaaaatgacaaaaaatctGACGTTTccgtttcgataaaaaaaacaagagaagTTTATCCGGATTCTTTAATGGAATGCAGTatagaagaaggaggagattCGGGAAATGATTACGAAACAAGTTACtacgataataaaatgttgacggaagaagaaaaagctcAACTGGAAGGATTTTTAGCGGAAACGAGTTTTGGCGGAGGGGATTTTCTGGCAAGTTCATACGATTCCGAAGGTacgggtaaaagaaaaagggatcAAACAGACGAATACCTCGAAGAAAAAGACAGCATAGATTTagacgatttgaaaaaaatgccAAAATGTCGTATTTGTTCGAAAGCGTTCAgtaagaaaaatcatttgaatcgTCATTTGAAACGATATCACAATTTGACGAAGGAACAAGTCAATTCAGGTAAATACGAAATATACGAAAACGGATCGGGAGATTTCGACGAGGTCGAGGGCGACGAATTTTACGACGAAGATGGAAATCCCATATTGAAACGTCCCAAAGGTACGTTCCCCTGCACCATTTGCAAAAAGACGTTCACGAGAAAGTATCACATGTACCGACACCGCAAGACTCAACACGGAATCAATTTTCCGAGCAAACAACAGCAGCGAGATGAGCCCTGGCTCAAATGTCAGAATTGCTCTTTGATATTCAACAACGATGAGGATTTTCAAAAGCACGAATGCGGTCACGCGgacgacgaagaagaagaagaggaaaaaaaatccgtcgTCGAACCCAAgagaaaacctaaaaattcatttaaatgtgCAATATGTAAGAACACGTTCGAAAATCACGACGGATTCAAGGATCACGTTTGTAAAAAGGGGTACAAGTGCGAAACCTGCGGCGAAACTTTCGAAAAAAGTAAACATTTGGCTAAACACGTGGAAACCCACGTGGAAAATCCAGGGGATTCCTTATCGTAA
Protein Sequence
MEESKLIIDEELCRICRSTEGGQLDIFGLSGAERNISTKIRECLPIKVSEKDGLPKTICAECAEKLDDFFNFRNMCRKIDSTFNELLHSDNNKSDSDDCSNSKTSETSKDKVDSSSTQLSIEIQSSSSPKKKQANLGDPQPEDYVLMKEETITVDNTTKINQEEKQVDPKGAKGKQQNTRTVLKGKFSVIHRRYIVAKGAFPCSLCGRCFLFNQGRPREGIPYADADIVQGDQDSNTDSPSDGLYPCPQCGKLFPRRTSLKRHQQIHFEGKKFVCKVCGKAFNRNEHLTRHMLSHTGGRPFQCDLCSKVFTRKEHLVRHRQCHDVSGVVIKEEPDDSVNSYGFSDFADATETKPFVCDICHSAYARREHMTKHKKVAHGIDADPESEPKPYCCNHCFKTFTRKEHLTRHKKIHIREAFSGNYEIADGVAPSLLISGPTGSKLQKDKSKKDVLIPLTVNCNISKLNNVTITPQPKGTTILKNPITKPQVSVVKPMTNVTPLSINKDTVTLEISGGSDGGEYKSKVGETLMNSILKNGKYGEISIVDVKNDKKSDVSVSIKKTREVYPDSLMECSIEEGGDSGNDYETSYYDNKMLTEEEKAQLEGFLAETSFGGGDFLASSYDSEGTGKRKRDQTDEYLEEKDSIDLDDLKKMPKCRICSKAFSKKNHLNRHLKRYHNLTKEQVNSGKYEIYENGSGDFDEVEGDEFYDEDGNPILKRPKGTFPCTICKKTFTRKYHMYRHRKTQHGINFPSKQQQRDEPWLKCQNCSLIFNNDEDFQKHECGHADDEEEEEEKKSVVEPKRKPKNSFKCAICKNTFENHDGFKDHVCKKGYKCETCGETFEKSKHLAKHVETHVENPGDSLS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01251254;
90% Identity
-
80% Identity
-