Basic Information

Gene Symbol
Aef1
Assembly
GCA_963082725.1
Location
OY720155.1:42673494-42673889[-]

Transcription Factor Domain

TF Family
zf-GAGA
Domain
zf-GAGA domain
PFAM
PF09237
TF Group
Zinc-Coordinating Group
Description
Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 0.00091 2.8 8.4 0.0 13 47 6 40 1 45 0.77
2 4 4.2e-05 0.13 12.7 0.0 21 50 42 71 38 73 0.87
3 4 0.0032 9.9 6.7 0.0 21 51 70 100 67 101 0.88
4 4 0.00013 0.42 11.0 0.1 21 46 98 123 96 128 0.90

Sequence Information

Coding Sequence
ATGCCTCGAGGACTAAGCAAAACTATGAAGATACCAAATGGTGAAAAGCCATTTCAATGTGATATATGTGACAAACAATTTCGTCAATTAAGCACATTGAcgaatcataaaaaaatacatacgGGAGAAAAACCATTTAAGTGTAATATATGTGAAAAACATTTTCGTCAATCAAGTACATTAACAAATCACGTTAAAATACATACTGGTGAGAAACCATTTAATTGCACTTATTGTGGTAAACAATTTCGTCAACTAAGTACATTGacaaatcatttaaaaattcataccGGTGAAAAACCATTTGAGTGTGCTGTCTGTAAAAAACAATTTCGTCAGTCAAGCACACTGAATAATCACATAAAAATTCATGCTAGcgataaaatttatatgtga
Protein Sequence
MPRGLSKTMKIPNGEKPFQCDICDKQFRQLSTLTNHKKIHTGEKPFKCNICEKHFRQSSTLTNHVKIHTGEKPFNCTYCGKQFRQLSTLTNHLKIHTGEKPFECAVCKKQFRQSSTLNNHIKIHASDKIYM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01164355;
90% Identity
iTF_01164355;
80% Identity
iTF_01164355;