Basic Information

Gene Symbol
-
Assembly
GCA_003055125.1
Location
NDXZ01002307.1:11527-18652[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 25 0.23 16 6.6 1.2 1 23 249 272 249 272 0.90
2 25 6.3e-05 0.0043 17.8 0.9 1 23 278 301 278 301 0.97
3 25 0.0054 0.37 11.7 0.3 2 23 331 352 330 352 0.97
4 25 1.1 75 4.5 3.3 1 23 429 452 429 452 0.88
5 25 0.12 8.4 7.4 0.6 2 23 460 481 459 481 0.97
6 25 0.00069 0.047 14.5 1.9 1 23 525 547 525 547 0.98
7 25 0.069 4.7 8.2 0.5 2 20 560 578 559 581 0.94
8 25 0.03 2.1 9.4 2.6 1 23 661 684 661 684 0.95
9 25 0.046 3.2 8.8 0.2 1 21 691 711 691 712 0.94
10 25 0.34 23 6.1 1.3 2 23 724 746 723 746 0.94
11 25 0.00034 0.024 15.5 0.4 2 23 761 782 760 782 0.97
12 25 2.5e-07 1.7e-05 25.4 1.9 1 23 788 810 788 810 0.98
13 25 3 2.1e+02 3.1 3.5 1 23 958 982 958 982 0.96
14 25 6.1 4.2e+02 2.1 3.9 1 21 989 1009 989 1010 0.93
15 25 0.008 0.55 11.2 2.3 1 23 1052 1075 1052 1075 0.96
16 25 0.0066 0.46 11.4 3.7 1 23 1082 1104 1082 1104 0.97
17 25 0.00012 0.008 16.9 0.4 2 19 1131 1148 1130 1150 0.95
18 25 0.0034 0.23 12.4 4.3 1 23 1206 1229 1206 1229 0.97
19 25 0.016 1.1 10.3 0.9 1 23 1266 1289 1266 1289 0.96
20 25 0.25 17 6.5 7.1 1 23 1319 1342 1319 1342 0.97
21 25 5.8e-07 4e-05 24.2 0.8 2 23 1371 1392 1370 1392 0.95
22 25 6.1e-06 0.00042 21.0 0.4 1 23 1398 1420 1398 1420 0.99
23 25 7.5e-06 0.00051 20.7 2.7 1 23 1426 1448 1426 1448 0.98
24 25 2e-06 0.00013 22.5 1.4 1 23 1454 1476 1454 1476 0.99
25 25 0.06 4.1 8.4 0.5 1 22 1482 1503 1482 1506 0.89

Sequence Information

Coding Sequence
atgaGTAACATTATGAAAAACGAATGTTTTATAAATGGGATTCGGTATAAATGTCGCACTTGCTTCGATCCAGGGCGAACAGTTTGCCATCTTACAGATGAGGCCATCAGCCCAAAGACTTGGCACGATTTATTAAAGGACATTGCGCGTTTACAGAATAATAATGAAGACCTACTACCCAATACCATGTGCTGCAAGTGTTCtggaaaacttaaaagtttCTATGAATTTATACTTCAGATTCATGATGTGAATAAAACATACACTCAATTGCTTACAAATTGTAAAGATCCATTACaggaaattgaaaattttgccgATTGCCTAGCAGAGTCAACAATTGATTTGCCATTCGAGCAATATATGCCAGAAATAAAATTAGAGGAAGATCTGGTTGACCCATCGTATAACACTGAActgaataataaaacaagtgttggtgaaacaaaattagaaaacttaaaaaattttttggaggaAAACTTAAATGACGACCTAAACTTAACGCCAAAACAATTAGTAGAGGACACAGATTATTTGAAAAGCaggcAACAACGCTTAAGCAATGACTACAACGACAATAATTACAGAAATGAATCCAGcTCCACGTCATCCGATGAAAGCGATTATGTGcccttgaaaaaatttaaaaaagaaaaaaacaatagaagTCAGCCAGTTACGCAGAAAAAAGGTCGAAAAGCCCCAGATTATTATGATCAAATCGAAAAGGTCAACGATCGTTTCGCTTGTCTCATTTGCCAAAAAACTTTCTCGCTACGTAAAGATTGTGGACGACATATCGCTTCGATTCATCTGCGCCAAAACATGTTTCCCTGTGAATTTTGTGGACAGAGCTTTAATCGTAAGGACAAAGTACAACTTCACATTAAGCGTATGCATGCAGACGGAGTAGTGTATCCGCCTAAACATAAAGAATGGTTATATGGAGATCGTTTATATTGCAAACCTACAACTTGGCGTCTTGTAAAGTGTAAATTGTGTGCTGAAACGTTTGCTAGCACCAAAGAACTTCGCTTGCATTTAGAAAGTCATATTGTTCTTGACAGCCTTCATGATTTAGAATTGAGCGACGACATAATTCAGCATTTGTTTCCAAATATGattgatttaaatattgttaaggaATATATACTAAAAGATATTCGTGAAAAACATTGGTTCAAATACTATACAGTCTTGAATGAAAATTCTTATGAGATGTCTATTAGCGATACGGAAGTAGAAGATTTGGAAGAAGAGTCAGCAAATCGTGACGCCAAGTACAAGTGCGATTTGTGTGCTAAAgagttttcctttaaatatcaagttttctgcCATTTAAAAGATGCTCATGGAAATGACGAAATTCCTTTAAAATGTGGACTATGCAAACTAGAATTTGTCTCcattaaaatgtatgaaaaacatTCACAAACCCACTGTCGTAATAGGCATAAAGTCTTACTTTGTGCTCATTGTCCGGCCAAATTTGTGTGGcctgaaaatatgaaaaaccaTAATTGCGCCCCAAAAATACTAGCGTTTCCACCATTAACAACTAAAGCCCAATTTACATGTAATGTATGTGAGCGTAAATTTGAGGTAAAGACAAAATATGAAAAGCATTTACTAACACATAGCGATGGCCGAACTGTATCAGCTAAAACAATTATACGTTGCGGTCTTTGTGCACATTCATTTGAAAGTTTACGACAATTGCGCCAACACATGCCTTTGCATGCCGATGGCAAAACTGCCATAGACTTTATAGGCAGTACATATATTAAACGTTTCGAACGTTCAAAAACAATTGATTATGCCCTACTGCAACAAGAGATACGAAATGCTTACAGTAAATCTCAAATAAGTCGTTTTTATCGAGCCCTCGATAAGGACGGCAATGAATTAGATTTATATGATTCTGATAGTGATACAGAGGAGCAAGTCGTTGATGGtgaacaaatgttaaaaaaagaatataccTGTGAGCTATGCaaagaaatgtttaacaaaCGAAAACCTCTTTTAAACCACCAGCACGAACGGCACAGTAATGTTCCGCTACCATATTCGTGTGAGAATTGTGTCCAGCAATATGTTAGTAATGATTTGTTGCAACAGCATTTAACGAGAGATTGCTGGAATGAACATCGTCGAATAGCTCAACAATGTGATTATTGTAATGCTCGTTTTATATGGCACAATAATCTATTAAAACACAAAGAAAttcagcacaaaaaacAGAAACACCCCAGACCTCAAAGAGCCAGTACACTCAAGTGTGAATACTgcgaaaaagtatttatatggCCCAAAGATTTGGTGCGTCACAGAAAAACTCACACCGAAGGCAAAAAATTCACTTGCCCACACTGTGATCGCAAATTTCAACGCAAAGACAACTTGTTGGCTCACATACGAATACATTGTCCTGATGGTATTCCCACAATTCTAAGTCCCGGTAAAAGTATCGACTATATACTGCCACATTTACTTAAACCACATGGCTGCAAACGCATCAAGTGCATGGTCTGCTTTTCCGAGCACAATCGTATACGTGATTTAAGGTCTCACCTACGAACACATCGTTATGCAGTTAATTtcgataaaagaaaagaaatcgaATCAATTGATGCGATATCATCACAATTCTATCCCGATGAATCGTTGCCTCTAACAGAAGAGGAGTTGGTTAAACGTATTGGTTCTGACATTGCGGTCGAGAACAATTTGGAACGCTTTTACTCCATAACAAGTGAACACGGCTACGAAGTTAATTTAGATAGTTCTGAAACGGAAAGCGATtccgatgatgatgatgaaaacgAGGAGGAGGAGGAAGAATGTGATGTTAAACCAAAACGTGTTTATACATGTGACTTATGCCCTCAATTGAGTTTTAAtcgtaaatacaaaattttcgatCATCAGCACAAACAGCATAAGTGGGAGGAAGCCCGTCATGTGTGCGTACATTGTAATGCACGTTTTCTTTCGTCATACATGCTGCAACTTCATCATAAGCATCAAtgtaaaaatccaaaaaaacgtCACTTTTGTCGTCGTTGCCCCTTGCGTTTCATGTGGAAAAATAACATGAAGACTCATATCGGAATGGAGCACGGTCAAGagATCGATTTTAATCGCCGCCATGAATGTTTTCTATGTCAAGAAAAGTTTCCTATTCAAAAGGAACTTAAACGTCACCTGACAACGCAACATTCTGCCGATGCAGCAATTCATTATTGTCTCCTGTGTCCAAAAACCTTCTTTAACATTGAACATCTTAACGAACATTTAAGTCGACATCGTTTAACAACAGCTGACGTGAAAGCCGTTGAAAGTATAATACATTCAACATGTTGGCCAAATGgtgaaaaaacaattaaatgcaaaatatgtgGCCAAATGTTTGATACTTTAAGCaacttaaaacaacattttttcgcTATAAATGCCCAAAACATGTGTGCCAGTCAACATGCACTTGAAAACTACTCTATAACTAATCAAAAAGGATTCGAATTACATTTAGAATTAGATTCGGAAACAGAAGTAGAAGATGAAATAGAAATGGGGAATAgtagagaaaacaaaaaaattatttatccttATAACTGTTGTATGTGCAGTATGTCGTTTAGGCGAAAATATCAAATAGCTCAACACCAACGCTCCATGCACAACTATGAAGTGCTGGAACTTAAATGTGAACGCTGCATTTTTAGAACCGTCTCACagAAAGTTTTAGACTATCACAGAGCCACTCAGTGTTTTAATGTTGAAAAGCAATACGAGTGTAAACAGTGcaactttaaatttatgtggcaagaaaatcttgaaaatcaTATAACCATATTTCATACACCAAAAGATTTGACCAATTTAACGGTGGCACTTAAGTCTTCCACCGAACCTATaccaacaaacaacaaaagttatacCAATATTTTCGAATGTATGGAATGTCACCGACGGTACAACCGTAAAGATCGTTATAaatctcattttaaaaaatttcacagtGACATGGAGCTATCGTCGCTCAACGTTACTAAACCAACCATTCGCAAACATTCGACCTCATCTAAAGCGGAGAAGAAATTTTTATGCGCCTTTTGTGGCCTctctttttcaaataattcaaATCTTACGGTGCACATGAGAAGGCACACGGGTGAGAAACCCTTTAAATGTGATCTTTGTGAAATGGCATTTCCACGTACATCTGATTTACAGGCTCACCGCCGCACCCACACTGGCGAGCGACCCTTTAAATGTTCTAACTGCGAGAAATCGTTTTCGCgacaatacaaattaaatgttCACAATCGCATACACACCGGTGAGCGGCCATACCAATGCACATTTTGCCCCAAATCATTTATCCAATCGAATGATTTGACCCTTCATTTGCGTCGTCATACGGGTGAAAGACCCTACATATGTGAAATTTGCGGTGAAGGCTTTATATGTGCAACCTCTCTGAAACAGCATCGAACATCAAGAGGTCATCAGgaagaaaatgatttaaaaaagtgtgtaCAACAGTTcgatatcaatttttaa
Protein Sequence
MSNIMKNECFINGIRYKCRTCFDPGRTVCHLTDEAISPKTWHDLLKDIARLQNNNEDLLPNTMCCKCSGKLKSFYEFILQIHDVNKTYTQLLTNCKDPLQEIENFADCLAESTIDLPFEQYMPEIKLEEDLVDPSYNTELNNKTSVGETKLENLKNFLEENLNDDLNLTPKQLVEDTDYLKSRQQRLSNDYNDNNYRNESSSTSSDESDYVPLKKFKKEKNNRSQPVTQKKGRKAPDYYDQIEKVNDRFACLICQKTFSLRKDCGRHIASIHLRQNMFPCEFCGQSFNRKDKVQLHIKRMHADGVVYPPKHKEWLYGDRLYCKPTTWRLVKCKLCAETFASTKELRLHLESHIVLDSLHDLELSDDIIQHLFPNMIDLNIVKEYILKDIREKHWFKYYTVLNENSYEMSISDTEVEDLEEESANRDAKYKCDLCAKEFSFKYQVFCHLKDAHGNDEIPLKCGLCKLEFVSIKMYEKHSQTHCRNRHKVLLCAHCPAKFVWPENMKNHNCAPKILAFPPLTTKAQFTCNVCERKFEVKTKYEKHLLTHSDGRTVSAKTIIRCGLCAHSFESLRQLRQHMPLHADGKTAIDFIGSTYIKRFERSKTIDYALLQQEIRNAYSKSQISRFYRALDKDGNELDLYDSDSDTEEQVVDGEQMLKKEYTCELCKEMFNKRKPLLNHQHERHSNVPLPYSCENCVQQYVSNDLLQQHLTRDCWNEHRRIAQQCDYCNARFIWHNNLLKHKEIQHKKQKHPRPQRASTLKCEYCEKVFIWPKDLVRHRKTHTEGKKFTCPHCDRKFQRKDNLLAHIRIHCPDGIPTILSPGKSIDYILPHLLKPHGCKRIKCMVCFSEHNRIRDLRSHLRTHRYAVNFDKRKEIESIDAISSQFYPDESLPLTEEELVKRIGSDIAVENNLERFYSITSEHGYEVNLDSSETESDSDDDDENEEEEEECDVKPKRVYTCDLCPQLSFNRKYKIFDHQHKQHKWEEARHVCVHCNARFLSSYMLQLHHKHQCKNPKKRHFCRRCPLRFMWKNNMKTHIGMEHGQEIDFNRRHECFLCQEKFPIQKELKRHLTTQHSADAAIHYCLLCPKTFFNIEHLNEHLSRHRLTTADVKAVESIIHSTCWPNGEKTIKCKICGQMFDTLSNLKQHFFAINAQNMCASQHALENYSITNQKGFELHLELDSETEVEDEIEMGNSRENKKIIYPYNCCMCSMSFRRKYQIAQHQRSMHNYEVLELKCERCIFRTVSQKVLDYHRATQCFNVEKQYECKQCNFKFMWQENLENHITIFHTPKDLTNLTVALKSSTEPIPTNNKSYTNIFECMECHRRYNRKDRYKSHFKKFHSDMELSSLNVTKPTIRKHSTSSKAEKKFLCAFCGLSFSNNSNLTVHMRRHTGEKPFKCDLCEMAFPRTSDLQAHRRTHTGERPFKCSNCEKSFSRQYKLNVHNRIHTGERPYQCTFCPKSFIQSNDLTLHLRRHTGERPYICEICGEGFICATSLKQHRTSRGHQEENDLKKCVQQFDINF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00975795;
90% Identity
-
80% Identity
-