Pmne020468.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Parnassius mnemosyne
Gene Symbol
Klhl10
Assembly
GCA_963668995.1
Location
CAVLGL010000080.1:12154904-12163056[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 2.1e-25 1.8e-22 81.5 0.0 2 108 56 162 55 164 0.92

Sequence Information

Coding Sequence
ATGGAATTTAATACGAAACATCGAAAATTATCTAAAACCAAAAATTCCGCTCGTAATCCATCCAATAATAAGCCCCGTTTGACTAAAAAGAAAACGGTTACGCGAAAACGTAAATGTGTTTGTCTTCCTGAAAATTATTCCATTGTTGAATTTCCTGCAATCTGGAACGAACTGAGGCAAAACGGTCAATTATGTGACGGCACAATAATATGTAGAGATATGAAATCAATACGTATTCATAGAGCCATACTGTCTGCTGTAAGCCCTTACTTCAAAGCAATATTTGTTAATTCATTGAAGAAAGGGGAGCCAGAAGAAACAGAGGTTTTTGTGGATGTACCAAGTTATTATATGAACTTAATTCTTGATTATGCGTACACAGGGTCGTGCACAGTTACCCCCGAAAATGTTGAAAACTTGCTACCTTATGCTGATCAATTTGATGTGGTAGGTATTATACAGTTATGTTGTCAGCTACTGTTGCAAGAATTAAGACCACACAACTGTCTTGGAATATTTAAATTTGCGCGATGCTATTTCTGCAATGAATTGgagaaaaaaggcaaactgtATATAAGACAGAACTTTGCTAGGATTCTTAAAGAATGTAATGAGTTTAAATCGTTGTCCTACGAAGAATTAGAGGACATATTGAGAGATGATGAATTAAATGTTCGAAATGAAGAAATAGTTTTCCAAGCAGTTAAAACATGGGTAGAACATGATCTTGAGAATAGACGGGTCTATATCCCTGCTTTGTTATCGTGTGTCCGATATGGTCAcataagttataaatattttaaatcaaaaatactTCAATGGCAACCAGTAATAGAAGATGAGAAATGTCAAGAAGTTCTGTACCCCGCTGTGGTATTTCTTACATTATTGGACTCTAGACCAGGTACTGAGGCGGATTTAAACGACCCTTTGGCGCGACCTCGAATACCCTACGAAATACTATTTGCAGTGGGTGGTTGGAGTGCTGGTAGCCCCACTAGCTTTGTTGAGACTTATGATACAAGAGCTGACCGATGGTTTCTCTCAATCCACATGGATCTAACGCCACGGGCATACCACGGTCTGTGCACGCTGAACAACCTTATCTACATGATCGGTGGATTCGATGGGAGTGATCACTTCAACACAGTCAGATGTTATGACCCCGTGTCGAATGTATGGCACGAGCGAGCTTGCATGTACCAGGCTAGATGCTACGTTAGCGTTGTGGTTCACGATGGTTTAATATACGCATTGGGAGGTTACAACGGCCGGACCCGGATGACCTCTGTAGAGCGATATCACCCTGATAAGAACCAGTGGGAGATGACTACGCCAATGAATAAGCAACGCTCAGATGCAAGTGCCGCTTCTTTAGGCGGTAAGatttacATAGTTGGCGGTTTCAATGGGCAAGAAGTGTTAAGTTCTGCGGAGATGTTCGACCCTGAGACGAAGCAATGGAGTTTCATCAGATCGATGCTCAGCCCGCGTTCGGGCGTAAGCCTTATCGCGTACAGGGACTCGCTGTATGCGCTTGGAGGTTTTAATGGATACAGCAGGTTGAATACTGGTGAAAGATTTACGCCCCACCGAGGTGGTGATTGGCAGGAAATAACGGAAATGTTCAGCGCAAGGAGTAACTTCGCAACTGTTTTATTAGATGATATGATTTTTGTCATCGGAGGCTTCAATgGCTCAACAACTATTCCCCACGTGGAATGTTACGACGGCGACACCCTAGAATGGTACGATGCTGCCCCAATGAACTTGAATCGGTCAGCACTAAGCGCTTGTGTCCTCGCCGGTTTGCCCAATGCTCGCTCTTTCTCGTATTTAGCAAAAGCCGTACCAGCAGCTGGAGCTGATCAGGCTCATCATTAG
Protein Sequence
MEFNTKHRKLSKTKNSARNPSNNKPRLTKKKTVTRKRKCVCLPENYSIVEFPAIWNELRQNGQLCDGTIICRDMKSIRIHRAILSAVSPYFKAIFVNSLKKGEPEETEVFVDVPSYYMNLILDYAYTGSCTVTPENVENLLPYADQFDVVGIIQLCCQLLLQELRPHNCLGIFKFARCYFCNELEKKGKLYIRQNFARILKECNEFKSLSYEELEDILRDDELNVRNEEIVFQAVKTWVEHDLENRRVYIPALLSCVRYGHISYKYFKSKILQWQPVIEDEKCQEVLYPAVVFLTLLDSRPGTEADLNDPLARPRIPYEILFAVGGWSAGSPTSFVETYDTRADRWFLSIHMDLTPRAYHGLCTLNNLIYMIGGFDGSDHFNTVRCYDPVSNVWHERACMYQARCYVSVVVHDGLIYALGGYNGRTRMTSVERYHPDKNQWEMTTPMNKQRSDASAASLGGKIYIVGGFNGQEVLSSAEMFDPETKQWSFIRSMLSPRSGVSLIAYRDSLYALGGFNGYSRLNTGERFTPHRGGDWQEITEMFSARSNFATVLLDDMIFVIGGFNGSTTIPHVECYDGDTLEWYDAAPMNLNRSALSACVLAGLPNARSFSYLAKAVPAAGADQAHH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00035861;
90% Identity
iTF_01143937; iTF_00197478; iTF_01142502; iTF_01148938; iTF_01148203; iTF_01146412; iTF_01144661; iTF_01140313; iTF_01145370; iTF_00922984; iTF_01115815; iTF_01495147; iTF_01495885; iTF_01494426; iTF_00707117; iTF_00157346; iTF_01332955; iTF_01141037; iTF_01143216; iTF_00180596; iTF_01130133; iTF_01149717; iTF_01147491; iTF_01492149; iTF_01176278; iTF_01264822; iTF_00467511; iTF_00724065; iTF_00666647; iTF_00468284; iTF_00341464; iTF_01010520; iTF_00858701; iTF_00249817; iTF_01075644; iTF_00636640; iTF_00382803; iTF_00968160; iTF_00844514; iTF_01141792; iTF_01341446; iTF_00355331; iTF_01071751; iTF_01386856; iTF_00356425; iTF_00651882; iTF_01153131; iTF_00012140; iTF_00961070; iTF_00076688; iTF_00013202; iTF_00026994; iTF_01385940; iTF_00008149; iTF_00022934; iTF_00072952; iTF_01387739; iTF_01388635; iTF_00146556; iTF_00640540; iTF_01220764; iTF_01387740; iTF_00720477; iTF_00958058; iTF_00195276; iTF_00942959; iTF_00204464; iTF_00855980; iTF_00986362; iTF_01079169; iTF_00843650; iTF_01080835; iTF_00958756; iTF_01078375; iTF_00420648; iTF_00824873; iTF_01151337; iTF_00284682; iTF_01506474; iTF_01507339; iTF_01080012; iTF_00419854; iTF_00063727; iTF_00419087; iTF_00960271; iTF_00461687; iTF_00796631; iTF_00985271; iTF_00959512; iTF_01508185; iTF_01034715; iTF_01033852; iTF_00695808; iTF_00159969; iTF_00248230; iTF_00842790; iTF_00247323; iTF_00723261;
80% Identity
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