Pmne037962.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Parnassius mnemosyne
Gene Symbol
egg
Assembly
GCA_963668995.1
Location
CAVLGL010000088.1:12430624-12504235[-]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 2.8 3.4e+04 -3.5 0.0 29 38 1587 1596 1557 1597 0.73
2 2 1e-13 1.3e-09 39.5 0.0 4 75 1628 1692 1625 1694 0.89

Sequence Information

Coding Sequence
ATGGATCCTGAACGAGATTTAGTTATAAATACAGTTCAAGATAGTAttcgaaataaagatttatcGAAGTCAGAAGATGGTGTTTCACGAACTTCTGGTGACAGTTATACCGATTGTGTAATTCAGGCTGATGAGATTAATGATAATATGGAGAGTAATTTTGAGGAACAGTCTGTGCAAAGTGTAAGTAATAAAAGTAAGACAGCTTGTACTATAGACAGGAAGGACGAAATCAATTACAAACAGTTACTATCAACACCTGTTCAGATAGATCCATTAGTACCACCACCTGAAATTAAAAAATCTGAAATTATTTATGatgaaaaatcttgtaaacaaaattTAGATTCCAAATCGGCCATTGACACTGAGATAAAACCATTTACAGATGATGAAAATAATAGTGATATGCAAGATGACGAGATACAGTTGAGatgggatgatgatgatgatgatgatgatgagctaaATTTAGATTGGGAGGAAATGCAAGATTCAGGTAATGCTGTTACTTGTATGAAGGAAAAAGTTGATTCTTGTGGAGTTAATGTTAAAATATTGCCTGAAGAACAAATAAACATGGATGTTGCATCAAAAAGATTATTTGAAAGTTCACAAAGTAACAAAAATATTAGAGTAGACTTGGAAATAACACATTCTCCTAAAAATCATAATGAAGAGGATAAGGTAGAGTCGGAGGTTTCAGTCCTAGATTCTTCTGCAGAAATTATAACAGAACATGGCCTGAAAAAACCTGATATGATGTTAGAAATACCTACACAGGAATTAATTGAATGTAtggatgatgacgatgatggacCAGATCTTTTAAGTAATTTGGAAATGTCTCCGGATGATGGGAGTATGGAAATATGTGTCACCAAAGatgtacaaaatattaaacataCTGATAATAACATATCATTGAATACTGATGCAACCATTAATGTAGATGCGCAGCAATTGAAAAAAGTTAGTAATAATGAATCATTAAATATAGTTACAACTATTAACAATGGTGTACTAAATGTGCAAAAAATGGGTGGTAATGAATTATTAAATACTGAACCTATTATTAATAAGGATATACCTAGTGAGAAACAATTTATTAATGATGAATCATTAAACATTGAGGCAACCAGTATTGAAGATGAACAAGAACAACCAAGTGTTAATGAATCATTTAATACTGATGCATCGATTAATAAAGATAAACAAAATGTCAATCAAGTTGATAATGAAGAATTAATAAATACTGCTGCAACTGTTAATGAAGATGTAAAAAATGTGAAGCAAGTCAGTAATAGTGAACCTTTAAAtaccgatacaactataaatgaTATACAAATTGTGAAACAAATTGGTAGTAATAAATCATTAAATACTGATGCAACTATTAATGAAGTAAAAAAGGtgaaaaatgttattaatagTGAGTCATTAAATACTGATTTATCTGTGAATGATGATAGACAAAATGTAAAACAAACCAGTAATAATGAATCATTAAATATAGATGTTACTATAAACGAAGATAAACAAAATGTGAAACAAATTGGTAAGAATGAATCGTCAATTATTAATGCAACTGTTAATGAGGATGTTAAAAATGTTGAGCAAAATAGTATGAAAGAATCACTAAATACTGATGCAACTGATAATGATGATCTACAAAATGGGAGAAAAGTAAATAACAATCAGTCATTAAATAGTGATTCAACTATTAATACAGAtgttctaaacataaatcaagGTTATAATGAACTATTGAAAACTAATGCAATTGCAACTTCAAATATGGAAATCAAATCAGAAAATAAGAATAAGGATACTGTGGCTATGGAAAGACAAGCAGACTTGCCCTATAAAAGCAGTGACCAAACAGAAACTGTTACTAAATGTaatcaaataaatattgagtCGATTTGTAAAAACCAAGCAGAAGTAAAGTTGGAAACAACACCAATTCAAGAAATAACTGAATCAAATGAACAGCAAGATAAACAAACATGTTTGCTAGATAGCGAGCAAAATGTCACATCTGTAAAGGATGAATCACAACCATCAACTTCTACAGCTTGTATGATCATGGAAATGAGAAGAGACTCTGATGAAGTGGGTGAGGTTTCTGATAGTCTTGGTCTTTTAGCAGAGTCAACAAGAGTGTTGGAGTATGATGAGGAGCAAgaagacgatgatgatggtgatgatgatgaagattttgACCAAGATGAAGAGAGTAGTAATCAAATGATAGCTGACTACTCAGAAGATTCTAATGAGAAGAAGAATGAGACAGACTTGCCTAAAAATGTTCAAATGGAAATTGATGATGCACAAGACTCAACAGAAAGAGAACTATCAGAAACACCTTTAGTAAAGAGTAAGGCAAATGAAGATTGTGAAGTGCAAATAAGTGATGTTAAGAGTGAagatgtttccagtaaaaatgaaaaAGACAACAAAACGGAAATTGAACTTTCTGATCCATCACATGTCATAAAATCTGGTGACAATGCTGAAGTGGAAGAACAAATTGCTGACAAGAttGTTCCAGGTGCAACTGACGAAGTTATAGAGCAAACAACAGCGGACACCATCGAGTGTCGGATTTTAAAATCACTGTTAGATAAAGATAACGATGAGAGCAAAACACATTTGCTTAAAGTGAAAGAGGAACCagTTAATGAGCCCCAGCTGTTGGATAGTCAGTCACAAGATAAAATACAGAATGAAGACTCGATAAATGAAGAGAATGTTGTCTTATTGGAAAGTTCTTCAGAAGatgaTTTTAGTGAAACGAAAGAAACAATTTCAAAGGCGCGAGTGGAAGCGGAGACACCAATAACGTCGGAAGATGTGTCCCGATCCAGTCTGCTAAcagaaatgaatgaaaaatactcATCTGATAGTAATTTAGAGAGCAAAGAGCAAGAAGATGGTGCGATGGATAAACCTAAAATTTCGGTTAAAGAAATGCTTAAATCATCAATGGGGTTAGAAGTGTTCAATGTTGATTCTGATGATGATGAGGTTCTACAGAAAGTCAGTAAAGTAAAGATACAAGAGGAATTAGATAAACTGCGCGGGAAAACCAAATGTGTTAACACTGCTTGTAAAAGCCCTATTGATGCAAAGTATTATGTGGCTGATTCTACTGTGTTGACTTTCTACGAAGCGGATCGGAAAAAAAAGCCGTTAGTCTGTGAGCCTTGTGCCGAGACAGTTGCAAAGAGAAATGAGAAGTTGATCAACGGAATCAGAACTTTTATGCCGCTCCTTGAACTAGAAACAAGCAAATGTAAGCAAGATTTGGTTGAGATATCCGACTCCGAATCTGAAGAAGACGAGGTAGTGGGGGATGACGACAAGGAAACGATTGGGGAAGCCGGCGCTAAACTTCTAGAAGAACAATTGGCGGACATGATTAACGAAACGTGGAAGAAATTCAAAATGGATTCCCGACTTACCGACGCGGAAGTTATTTTGCAAGATGAAATAAACCGTTTGAATAagGAGAATAAAGAAATCGACGACATGTTAAACGAGTGCCAAGTAGCGACCGATAAGCTGCGGAACGAATTGTATGCGACTTTCGAGCAAGAGCGAAAGGAGTTACCGCCCATTGTTATTAACGACAGGCCCAACATTACGTTGTCCTGTTTTGAGGACAGCACAGGAGAAAAATTAGAGTCGCCACAGACACGTATGAAACGTCGCATGTCCACCATTAGTGATACACCTGCCAAAAAGCTGGCCATCTTAACCGGACAGAGTACAACAGAAAATGAGTTAGAACAgAATGTGGAGGTATCTGTGGTGAAGCTGTCGGCGGAGGCGGCACCCGCCGACCTGCCGCCGCCGGGAGAAGTGACGCGGCCGCCACTGCGCGTCGGCATGACGGTGTATGCCATGAGGAATGCTTTCGGACTTTGGCTCAAGGCGAAGATTGTCGAGACGCAGGCTAAAAATTTGTCAACAGCCCCGTTCACGATGTGCCGCGTAAGGTTCGAGCACAAAGTCAATAAGAATCCGTTCAAATTGTTGCCTGCGCGCTGCCTTGCGTATTCTGATCCTTCCGACGTTCGTCTTACAATAGGTACTCGAATAATTGCATCTTCCGACAAAAGAGAATCGTTCTATTCAGGAGTCGTCGCGGAGGTTCCAAACCCTGTTAACAATTATAGATATTTGGTATTCTTTGACGACGGGCATGCAAAATATGCACAACACGCGCACACACGTCTGGTGTGCGAGTGTTCACCGTTGGTTTGGGAAGAGGTGCATCCATACTCGCGCGACTTCGTGCGCCAGTACCTGCTGTCGTATCCCGAGCGACCAATGGTGCGGCTGCATCCAAGACAGAACCTCAAGGCCGAATGGAACGGCAAATGGTGGACGTCGAAGGTGATACAAGTAGACGCATCGCTGGCGCTGATCAAGTTGGCGGGTGACCGGCTGGAGTGGATCTACCGTGGTTCAACTCGCCTGGCGCCGCTCTACCTGGAGCTGCAGGCTGCCGAGCGGCACCGAACCCGCCCCATGCCCAGGTCGGGCCCGCAGCACCGGACGAACATGCCATACGTGGAATACACGCGCTACGACGAGCAACAACCTTCCAAAACACCTGCACCACAAACGCCGCAACAAAATGAAGAAATACGTCGACAGCGCGCCGTGGCCAAGAAGTCGACAACGACGAGCCTGCCGCCGGCGCCCGCACCCGCGCCGCCTGTCAACGCCGCCAACTTGGACAACGTCACCAGCCGAGTTGTGTATTACACGCCCAAGAATGCAGTACGCCCGCACAAGATGGTGCCGCATACGTGCGGACCGAAATGCAGACGCACAGACGTGTTGGCGCTCAAAGACCTACGCACGTACAACCCCTTGGCTAAGCCACTACTCAGTGGCTGGGAGAGGCAAATCGTGCGCTTCAAGGGGCACAAGGAGGTGATGTACCGCGCGCCGTGCGGGCGGCGGCTGCGCTGCATGGCCGAGCTGCACCGCTACCTGCGCGCCGTGCGCTCCGACATGTCCGTCGACCTGTTCGACTTCGCGCCCTCCACGCACTGCCTCGCCGAGTTCGTGCTCAACAAGTGCCTCGTCGGCAAGAAGGACCTATCGCATGGCAAAGAAAACGTGCCAGTGCCGTGCGTGAACTACTACGACGAGTCTTTGCCGGAGTTTTGCTCGTACAACACTGAACGCACGCCCACGGCCGGCGTGCCGCTCAACATCGACCCGGACTTCCTGTGCGGCTGCGACTGCGAGGACGACTGCGAGGACAAAACAAAATGTGCTTGTTGGAGGATGACGCTAGAGGGCGCACGAACAATTGGTTTAGACGGGGATGTTGGCTACGTGTACAGAAGATTGCCTGAACCGTTGCCTTCCGGGATTTATGAATGTAACTCCAgGTGTAAATGTAAAAATACGTGTTTAAATCGAGTGGCGCAACATCCTCTCCAGCTGAAACTACAAGTTTTCAAAACTCTCAACCGTGGATGGGGCATACGAGCACTCAATGACGTACCAAAAGGAGCATTTCTGTGTGTTTATGCGGGAAATTTACTGACTGATGCAACCGCAAACTTGGACGGCCTGAACGAAGGCGACGAGTATCTCGCCGAGCTTGACTACATTGAAGTCGTGGAGCAGTTGAAGGAGGGCTTCGAAGAAGACATCCCGGAGTTTCTCAAAGAACCCGAAAGAAGATCCTCTGCTATAGAATCTGTTGAAGAACAAGAAACATCTTCTGAGGAAGAAGAGGTAAAGACTTCAAAAGATGAGAGAGATGACGACTTCCGGCCTGGGTACTTCGAAATGGGCTCTATGGAATTTAGTAAACGTTTGCGTACACGAGAAAAACGCATGAAGGAGCGCTACAACAATCTGGAAAATAAAGACAAAGAAAAGGATAAgcaaaaggaaaaagaaaaaagaaaagatacAGAAAAGGATGAAGGGGAAAAAGACAACGGCGATGATGACTGCATAACTATAAGCGATGACGAAGAGGtGAGAGAGCCGTCGCGATTTACGGCGCAAGCGGGGATGGACGCAAATCAATTGGTATCAAAATACAGGTCAGTACGTTCCTACTTCGGCAAGGACGAGGCGTGCTACATCATGGACGCTAAGGTCCAAGGCAATATTGGTCGATATCTAAATCACTCCTGCTGTCCCAACGTGTTCGTCCAGAACGTGTTTGTGGACACGCACGACCCGCGGTTCCCGTGGGTGGCATTCTTCGCGCTCTCCCACATCCGTGCCGGCACGGAGCTCACCTGGAACTACAACTATGACGTGGGTTCCGTGCCTGGGAAAATTCTGTATTGCTATTGCGGGGCGGTCAACTGCAGGGGaagactactttaa
Protein Sequence
MDPERDLVINTVQDSIRNKDLSKSEDGVSRTSGDSYTDCVIQADEINDNMESNFEEQSVQSVSNKSKTACTIDRKDEINYKQLLSTPVQIDPLVPPPEIKKSEIIYDEKSCKQNLDSKSAIDTEIKPFTDDENNSDMQDDEIQLRWDDDDDDDDELNLDWEEMQDSGNAVTCMKEKVDSCGVNVKILPEEQINMDVASKRLFESSQSNKNIRVDLEITHSPKNHNEEDKVESEVSVLDSSAEIITEHGLKKPDMMLEIPTQELIECMDDDDDGPDLLSNLEMSPDDGSMEICVTKDVQNIKHTDNNISLNTDATINVDAQQLKKVSNNESLNIVTTINNGVLNVQKMGGNELLNTEPIINKDIPSEKQFINDESLNIEATSIEDEQEQPSVNESFNTDASINKDKQNVNQVDNEELINTAATVNEDVKNVKQVSNSEPLNTDTTINDIQIVKQIGSNKSLNTDATINEVKKVKNVINSESLNTDLSVNDDRQNVKQTSNNESLNIDVTINEDKQNVKQIGKNESSIINATVNEDVKNVEQNSMKESLNTDATDNDDLQNGRKVNNNQSLNSDSTINTDVLNINQGYNELLKTNAIATSNMEIKSENKNKDTVAMERQADLPYKSSDQTETVTKCNQINIESICKNQAEVKLETTPIQEITESNEQQDKQTCLLDSEQNVTSVKDESQPSTSTACMIMEMRRDSDEVGEVSDSLGLLAESTRVLEYDEEQEDDDDGDDDEDFDQDEESSNQMIADYSEDSNEKKNETDLPKNVQMEIDDAQDSTERELSETPLVKSKANEDCEVQISDVKSEDVSSKNEKDNKTEIELSDPSHVIKSGDNAEVEEQIADKIVPGATDEVIEQTTADTIECRILKSLLDKDNDESKTHLLKVKEEPVNEPQLLDSQSQDKIQNEDSINEENVVLLESSSEDDFSETKETISKARVEAETPITSEDVSRSSLLTEMNEKYSSDSNLESKEQEDGAMDKPKISVKEMLKSSMGLEVFNVDSDDDEVLQKVSKVKIQEELDKLRGKTKCVNTACKSPIDAKYYVADSTVLTFYEADRKKKPLVCEPCAETVAKRNEKLINGIRTFMPLLELETSKCKQDLVEISDSESEEDEVVGDDDKETIGEAGAKLLEEQLADMINETWKKFKMDSRLTDAEVILQDEINRLNKENKEIDDMLNECQVATDKLRNELYATFEQERKELPPIVINDRPNITLSCFEDSTGEKLESPQTRMKRRMSTISDTPAKKLAILTGQSTTENELEQNVEVSVVKLSAEAAPADLPPPGEVTRPPLRVGMTVYAMRNAFGLWLKAKIVETQAKNLSTAPFTMCRVRFEHKVNKNPFKLLPARCLAYSDPSDVRLTIGTRIIASSDKRESFYSGVVAEVPNPVNNYRYLVFFDDGHAKYAQHAHTRLVCECSPLVWEEVHPYSRDFVRQYLLSYPERPMVRLHPRQNLKAEWNGKWWTSKVIQVDASLALIKLAGDRLEWIYRGSTRLAPLYLELQAAERHRTRPMPRSGPQHRTNMPYVEYTRYDEQQPSKTPAPQTPQQNEEIRRQRAVAKKSTTTSLPPAPAPAPPVNAANLDNVTSRVVYYTPKNAVRPHKMVPHTCGPKCRRTDVLALKDLRTYNPLAKPLLSGWERQIVRFKGHKEVMYRAPCGRRLRCMAELHRYLRAVRSDMSVDLFDFAPSTHCLAEFVLNKCLVGKKDLSHGKENVPVPCVNYYDESLPEFCSYNTERTPTAGVPLNIDPDFLCGCDCEDDCEDKTKCACWRMTLEGARTIGLDGDVGYVYRRLPEPLPSGIYECNSRCKCKNTCLNRVAQHPLQLKLQVFKTLNRGWGIRALNDVPKGAFLCVYAGNLLTDATANLDGLNEGDEYLAELDYIEVVEQLKEGFEEDIPEFLKEPERRSSAIESVEEQETSSEEEEVKTSKDERDDDFRPGYFEMGSMEFSKRLRTREKRMKERYNNLENKDKEKDKQKEKEKRKDTEKDEGEKDNGDDDCITISDDEEVREPSRFTAQAGMDANQLVSKYRSVRSYFGKDEACYIMDAKVQGNIGRYLNHSCCPNVFVQNVFVDTHDPRFPWVAFFALSHIRAGTELTWNYNYDVGSVPGKILYCYCGAVNCRGRLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01153999;
90% Identity
-
80% Identity
-