Basic Information

Insect: Parnassius glacialis
Gene Symbol: -
Assembly: GCA_033319125.1
Location: JAVANC010000014.1:24347752-24357864[-]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 3e-12 2.6e-08 35.2 0.1 7 50 67 112 63 123 0.88

2 14 5.5e-07 0.0047 18.4 0.1 27 50 131 154 119 162 0.84

3 14 5.5e-07 0.0047 18.4 0.0 27 50 173 196 164 206 0.84

4 14 2.5e-06 0.021 16.3 0.1 27 49 215 237 202 245 0.80

5 14 1e-06 0.0087 17.5 0.1 28 49 242 263 235 270 0.86

6 14 5.6e-07 0.0048 18.3 0.1 27 50 283 306 270 312 0.84

7 14 6.8e-07 0.0058 18.1 0.0 27 49 357 379 329 388 0.84

8 14 3.8e-07 0.0032 18.9 0.0 24 51 427 453 408 473 0.81

9 14 4.2e-07 0.0035 18.8 0.1 27 50 530 553 506 562 0.79

10 14 5e-07 0.0042 18.5 0.0 27 50 599 622 571 643 0.82

11 14 5.3e-07 0.0045 18.4 0.0 27 50 668 691 654 698 0.84

12 14 8e-07 0.0068 17.8 0.0 27 49 767 789 751 792 0.84

13 14 5.6e-07 0.0048 18.3 0.0 29 50 833 854 802 863 0.82

14 14 3.3e-06 0.028 15.9 0.0 27 49 900 922 872 930 0.82

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	3e-12	2.6e-08	35.2	0.1	7	50	67	112	63	123	0.88
2	14	5.5e-07	0.0047	18.4	0.1	27	50	131	154	119	162	0.84
3	14	5.5e-07	0.0047	18.4	0.0	27	50	173	196	164	206	0.84
4	14	2.5e-06	0.021	16.3	0.1	27	49	215	237	202	245	0.80
5	14	1e-06	0.0087	17.5	0.1	28	49	242	263	235	270	0.86
6	14	5.6e-07	0.0048	18.3	0.1	27	50	283	306	270	312	0.84
7	14	6.8e-07	0.0058	18.1	0.0	27	49	357	379	329	388	0.84
8	14	3.8e-07	0.0032	18.9	0.0	24	51	427	453	408	473	0.81
9	14	4.2e-07	0.0035	18.8	0.1	27	50	530	553	506	562	0.79
10	14	5e-07	0.0042	18.5	0.0	27	50	599	622	571	643	0.82
11	14	5.3e-07	0.0045	18.4	0.0	27	50	668	691	654	698	0.84
12	14	8e-07	0.0068	17.8	0.0	27	49	767	789	751	792	0.84
13	14	5.6e-07	0.0048	18.3	0.0	29	50	833	854	802	863	0.82
14	14	3.3e-06	0.028	15.9	0.0	27	49	900	922	872	930	0.82

Sequence Information

Coding Sequence: ATGAACCGTTTCTTTAACGTGAATTTTGGCTGGGATTTAGCTGATTTAGATGccaaacaattttgtaaatttattcaaaataATGGATCCAGACCATCATCAGCTTTATCATCACGATCAGACGGTGACAGCACAGAGTCTGGGTCGGCACCGGGCATCCGCGGGCGGCGCTCGACGACGGAGATGTCGTCGCCGCTGCTGCGAGCGCCGCTGGAGCGCGGCTGGCGGCGTGAGCTCGTGTACCGCGCCGCGCTCGACGCGCACTCGCGCCGCAACGCCGACATCTACTACTACACGCCGCACGGCAAGAAGCTGCGCTCCACCAGGGAGGTACGTAgagccgcaccgcaccgcaccgcaccgcaccgcaccgcaccgcaccgcaccgcaccgcgccGCAACGCCGACATCTACTACTACACGCCGCACGGCAAGAAGCTGCGCTCCACCAGGGAGGTACGTAgagccgcaccgcaccgcaccgcaccgcaccgcaccgcaccgcaccgcaccgcaccgcgccGCAACGCCGACATCTACTACTACACGCCGCACGGCAAGAAGCTGCGCTCCACCAGGGAGGTACGTAgagccgcaccgcaccgcaccgcaccgcaccgcaccgcaccgcaccgcaccgcaccgcgccGCAACGCCGACATCTACTACTACACGCCGCACGGCAAGAAGCTGCGCTCCACCAGGGAGAGCCGCACCGCACCGCGCCGCAACGCCGACATCTACTACTACACGCCGCACGGCAAGAAGCTGCGCTCCACCAGGGAGGTACGTAGTGctgcaccgcaccgcaccgcaccgcaccgcaccgcaccgcaccgcaccgcgccGCGCCGCAACGCCGACATCTACTACTACACGCCGCACGGCAAGAAGCTGCGCTCCACCAGGGAGGTACGTAgagccgcaccgcaccgcaccgcaccgcaccgcaccgcaccgcaccgcgccGCAACGCCGACATCTACTACTACACGCCGCACGGCAAGAAGCTGCGCTCCTCCAGGGAGGTACGTAgagccgcaccgcaccgcaccgcaccgcaccgcgccGCGCCGCAACGCCGACATCTACTACTACACGCCGCACGGCAAGAAGCTGCGCTCCACCAGGGAGGTACGTAGTGctgcaccgcaccgcaccgcaccgcaccgcaccgcaccgcaccgcaccgcgccGCAACGCCGACATCTACTACTACACGCCGCACGGCAAGAAGCTGCGCTCCACCAGGGAGGGAGGTACGTAGTGctgcaccgcaccgcaccgcaccgcaacGCCGACATCTACTACTACACGCCGCACGGCAAGAAGCTGCGCTCCACCAGGGAGGTACGTAgagccgcaccgcaccgcaccgcaccgcaccgcaccgcgccGCAACGCCGACATCTACTTCTACACGCCGCACGGCAAGAAGCTGCGCTCCTCCAGGGAGGTACGTCgagccgcaccgcaccgcaccgcaccgcaccgcaccgcgccGCAACGCCGACATCTACTACTACACGCCGCACGGCAAGAAGCTGCGCTCCACCAGGGAGGTACGTAgagccgcaccgcaccgcaccgcgccGCAACGCCGACATCTACTACTACACGCCGCACGGCAAGAAGCTGCGCTCCACCAGGGAGGTACGTAgagccgcaccgcaccgcaccgcaccgcaccgcgccGCAACGCCGACATCTACTACTACACGCCGCACGGCAAGAAGCTGCGCTCCACCAGGGAGGTACGTAgagccgcaccgcaccgcaccgcaccgcaccgcaccgcgccGCAACGCCGACATCTACTACTACACGCCGCACGGCAAGAAGCTGCGCTCCACCAGGGAGGTACGTAGTGctgcaccgcaccgcaccgcaccgcaacGCCGACATCTACTACTACACGCCGCACGGCAAGAAGCTGCGCTCCTCCAGGGAGGTACGTCgagccgcaccgcaccgcaccgcaccgcaccgcaccgcaccgcaccgcgccGCAACGCCGACATCTACTACTACACGCCGCACGGCAAGAAGCTGCGCTCCACCAGGGAGGTACGTAGAGCCGCACCGCACCGCGCCGCAACGCCGACATCTACTACTACACGCCGCACGGCAAGAAGCTGCGCTCCACCAGGGAGGGAGGTACGTAGTGctgcaccgcaccgcaccgcaccgcaacGCCGACATCTACTACTACACGCCGCACGGCAAGAAGCTGCGCTCCTCCAGGGAGGTACGTCgagccgcaccgcaccgcaccgcaccgcaccgcaccgcaccgcaccgcgccGCAACGCCGACATCTACTACTACACGCCGCACGGCAAGAAGCTGCGCTCCACCAGGGAGGTACGTAGTGCTGCACCGCACCGCGCCGCAACGCCGACATCTACTACTACACGCCGCACGGCAAGAAGCTGCGCTCCACCAGGGAGGTACGTAgagccgcaccgcaccgcaccgcaccgcaccgcaccgcaccgcaacGCCGACATCTACTACTACACGCCGCACGGCAAGAAGCTGCGCTCCACCAGGGAGGTACGTAgagccgcaccgcaccgcaccgcaccgcaccgcgccGCAACGCCGACATCTACTACTACACGCCGCACGGCAAGAAGCTGCGCTCCACCAGGGAGGTACGTAGTGctgcaccgcaccgcaccgcaccgcaccgcaccgcgccGCAACGCCGACATCTACTTCTACACGCCGCACGGCAAGAAGCTGCGCTCCACCAGGGAGGTACGTAGTGctgcaccgcaccgcaccgcaccgcaccgcaccgcaccgcaccgcaccgcaccgcaccgcaccgcaccgcaccgcaccgcatcGCACCGCGCCGCACCGCACCGCGCCGCGCCGCAACGCCGACATCTACTACTACACGCCGTACGGCAAGAAGCTGCGCTCACGCACAAAATTAACTTAGTGTCTAAACCATGA
Protein Sequence: MNRFFNVNFGWDLADLDAKQFCKFIQNNGSRPSSALSSRSDGDSTESGSAPGIRGRRSTTEMSSPLLRAPLERGWRRELVYRAALDAHSRRNADIYYYTPHGKKLRSTREVRRAAPHRTAPHRTAPHRTAPRRNADIYYYTPHGKKLRSTREVRRAAPHRTAPHRTAPHRTAPRRNADIYYYTPHGKKLRSTREVRRAAPHRTAPHRTAPHRTAPRRNADIYYYTPHGKKLRSTRESRTAPRRNADIYYYTPHGKKLRSTREVRSAAPHRTAPHRTAPHRTAPRRNADIYYYTPHGKKLRSTREVRRAAPHRTAPHRTAPHRAATPTSTTTRRTARSCAPPGRYVEPHRTAPHRTAPRRNADIYYYTPHGKKLRSTREVRSAAPHRTAPHRTAPHRTAPQRRHLLLHAARQEAALHQGGRYVVLHRTAPHRNADIYYYTPHGKKLRSTREVRRAAPHRTAPHRTAPQRRHLLLHAARQEAALLQGGTSSRTAPHRTAPHRAATPTSTTTRRTARSCAPPGRYVEPHRTAPRRNADIYYYTPHGKKLRSTREVRRAAPHRTAPHRAATPTSTTTRRTARSCAPPGRYVEPHRTAPHRTAPRRNADIYYYTPHGKKLRSTREVRSAAPHRTAPQRRHLLLHAARQEAALLQGGTSSRTAPHRTAPHRTAPRRNADIYYYTPHGKKLRSTREVRRAAPHRAATPTSTTTRRTARSCAPPGREVRSAAPHRTAPQRRHLLLHAARQEAALLQGGTSSRTAPHRTAPHRTAPRRNADIYYYTPHGKKLRSTREVRSAAPHRAATPTSTTTRRTARSCAPPGRYVEPHRTAPHRTAPHRNADIYYYTPHGKKLRSTREVRRAAPHRTAPHRAATPTSTTTRRTARSCAPPGRYVVLHRTAPHRTAPRRNADIYFYTPHGKKLRSTREVRSAAPHRTAPHRTAPHRTAPHRTAPHRTASHRAAPHRAAPQRRHLLLHAVRQEAALTHKINLVSKP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -