Basic Information

Insect: Pararge aegeria
Gene Symbol: L
Assembly: GCA_905163445.1
Location: NC:11924750-11954808[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 1.2e-06 4.9e-05 23.2 2.4 1 23 97 119 97 119 0.99

2 18 7.9 3.2e+02 1.7 7.7 1 23 125 147 125 147 0.97

3 18 8.5e-06 0.00035 20.5 4.1 1 23 153 175 153 175 0.99

4 18 1.2e-05 0.00049 20.0 0.1 1 23 181 203 181 203 0.98

5 18 0.0012 0.048 13.7 0.3 2 23 219 241 218 241 0.94

6 18 6.1 2.5e+02 2.0 0.1 9 23 272 287 268 287 0.93

7 18 0.3 12 6.1 0.0 3 23 343 363 342 363 0.97

8 18 0.17 6.9 6.9 0.0 3 23 378 398 377 398 0.91

9 18 0.00019 0.0078 16.2 1.2 1 23 406 429 406 429 0.91

10 18 0.0089 0.36 11.0 0.1 1 23 434 457 434 457 0.94

11 18 2.7e-05 0.0011 18.9 0.5 1 23 517 541 517 542 0.96

12 18 0.0002 0.0082 16.1 0.1 2 23 601 622 600 622 0.96

13 18 0.055 2.3 8.5 0.0 1 23 630 652 630 652 0.98

14 18 6.9 2.8e+02 1.9 0.7 2 23 660 681 659 682 0.91

15 18 9.7 4e+02 1.4 0.0 3 23 689 709 688 709 0.93

16 18 0.47 19 5.5 0.6 1 23 756 778 756 778 0.94

17 18 0.0054 0.22 11.6 0.1 1 20 786 805 786 808 0.95

18 18 0.1 4.2 7.6 0.3 1 23 815 837 815 837 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	1.2e-06	4.9e-05	23.2	2.4	1	23	97	119	97	119	0.99
2	18	7.9	3.2e+02	1.7	7.7	1	23	125	147	125	147	0.97
3	18	8.5e-06	0.00035	20.5	4.1	1	23	153	175	153	175	0.99
4	18	1.2e-05	0.00049	20.0	0.1	1	23	181	203	181	203	0.98
5	18	0.0012	0.048	13.7	0.3	2	23	219	241	218	241	0.94
6	18	6.1	2.5e+02	2.0	0.1	9	23	272	287	268	287	0.93
7	18	0.3	12	6.1	0.0	3	23	343	363	342	363	0.97
8	18	0.17	6.9	6.9	0.0	3	23	378	398	377	398	0.91
9	18	0.00019	0.0078	16.2	1.2	1	23	406	429	406	429	0.91
10	18	0.0089	0.36	11.0	0.1	1	23	434	457	434	457	0.94
11	18	2.7e-05	0.0011	18.9	0.5	1	23	517	541	517	542	0.96
12	18	0.0002	0.0082	16.1	0.1	2	23	601	622	600	622	0.96
13	18	0.055	2.3	8.5	0.0	1	23	630	652	630	652	0.98
14	18	6.9	2.8e+02	1.9	0.7	2	23	660	681	659	682	0.91
15	18	9.7	4e+02	1.4	0.0	3	23	689	709	688	709	0.93
16	18	0.47	19	5.5	0.6	1	23	756	778	756	778	0.94
17	18	0.0054	0.22	11.6	0.1	1	20	786	805	786	808	0.95
18	18	0.1	4.2	7.6	0.3	1	23	815	837	815	837	0.94

Sequence Information

Coding Sequence: ATGATCATGCTATTCAAAGGCAACAGCAGCAGGTTGGAGCATCTAATAGAGAAGATTCAGGCGAATAAGGAAAACCACGACGTGACCACAGAAGATTTAAAACAAGCGTTGGGCAGCGTCGGCAGCGTGGGCAGCGTCGGTAGCACGGGGGGCAGCTCGTGGCCGTCGTCGACGCCTGAGCCATCACCCTCGCCATCCTCCACGCCGACGTCCCACGACGCCGTCGACGCAGAGGCGGACGCGGACGCCGACCCGCCGTTCACGCTGGGTGCGACTGAGCACACTCCCTACAAATGTAAATTCTGCGACAAGGCCTTCCCTAGGCTGTCCTACCTCAAGAAACATGAACAGACCCATTCTGATCAGATGCCGTTCCGATGTGAGTTCTGCTCGCATTTGTTCAAGCACAAGAGGTCCCGCGACCGACACGTCAAACTTCACACCGGTGATCGGAAATACCGCTGCGCGCACTGCGAATCTGCTTTCTCCAGAAGCGACCATCTGAAGATACACATGAAAACTCACGACAACCAAAAGCCGTTTCAATGCACCGTTTGCAACCGAGGGTACAGCACAGCCGCCGCTCTCACGTCCCACATGCAGGGGCACAAACGGGAGCGTGAGGGTCGTGAAACAAATCGAAAGCGGGCCTTGCATTGCTTGCGTTGCGGAGATGCATTCCGGCGACCTGATCTTctacaagccCACATGTCAAGTGTCCACGGCGTTGATGGAACCGCAATGACACCCCCGCGCCGAGTCGCTTCTCAGCCGCCGCCTACTCTACTTGCATGCATATATTGCACTCGGGATACATTTACCAGCATGGAACAGTTACAGCTACATGTACGCGCTGCACACTCAGCACTGTTGAATGGAGAAACTTCTGTACAGTACACAGTCGATCAGCCTATGCCGACCGACTTAAGTAGACGTAGTCCCGAAAATCTATCGCCAGCTAAACGTGTTCGGTTAAACTCGGGTTCTACAACACCAAAAACCGCTCTATCCCCGAGTACTCTTTTATGTAATCAGTGTGACGCAGCACTTCCAGACTTCGAAGCTTTTCGAGCACATTTAAAAGCTCATATTGAAGAAGGTGGAGAGCTGGGAAGGACGAGTCCCGCACCTTGTCTCCACTGTGGGGCTACGTTCGCCGATGCGGCGGCCTCTGAGCGTCACTTGGCCGCACATTATCTCGCCGTGTCCTGTGAATATACCTGCCACAGTTGTGTGCGCAGTTTCCCTACACCTGAAGATTTGCAGAAACATCTTTTTGACATGCACGCTCATCATATGTACCAGTGCAATCtttgtaaagaaatatttgattcaaAAGTAGCCATACAGgCACATTTCGCAATGGCTCATAGTGCCGAAAACAAAGTGTGGGTATGTCGGTCCTGTGGTTCCGCTGGAGGAGCGCTGCGTACGGAGGCTGAAGGGTCGGCCCACGTGCGAGCACGTCACGCGGCCGCGCGCTGCACTTGCGGCGCCGTGCTCTCCGGCTCACGTGCGCTCAGGGCCCACGCGGCGGCACATCACACGTTCCGCTGCCCTGTTCCAACTTGTACTGAATCCTTCGCTGTGCAATATCTACTAGAGCGCCACATACAAACTCATCATGCTGTTGCGCATCAAGGTGCCAACGGTGATATAATAAGAGCCAAACGAACAGAAAATAACAACGCCACTGAAGGAGACGGAGCGAGTCCTCCATGCGTTAGTGGGGGCGATGGCCATGCGCCTGTCACGTCAGGCGGAGATGAACGCAGGCGTAAGAATGGCGCTGTGGCATTACAGTGTGCATACTGTGGCGAACGTACGCGAAGTAGGGCTGAACTAGAGGCGCACACTCGTGCCCACTCCGGAGCAGGCGCGGCGCGGCACAAGTGCCTCATCTGTGACGAAGTGCTACCTTCTGCTGGCGTACTTGCTGAGCATAAACTTACACATTGcaaggTAGTTGCTGGTGATACTTGCGCTCGATGTCGATCAAGGCTACCATCAGAAGAGGCGTTCTTGACTCACATGGCACGGCACCATCCTGCATTACCAGCCCCCTGCGTCATTTGCCGTCAGACCTTAGCTTCGGAGGCTGAAGCGCGTTTGCACGCCCGCTTTCATTTAAGACCGAATGAGGACGAACAGAGATGTGCAATATGTCTCCGAGCTTTGTCGGAAAGTGAGGCTGGCGAAGGAGCGAGGGCCTGCAGTGCTTGTTACGCTCGTCACGCTGCCCCGAGACCACCTCCTTCGTCCGATCATGACTGCCGTCTTTGCCGTCGAACCCTCGGCTCTCCTACCCGCCTACAAGCCCATCTTATAGAACACACATTCGCTGGCATTGGAGCGTTTACATGCTACCTTTGCTCGGCTATGTTTACAAGCGCAGCGGGACTGCAAAGGCATTTGCCAGAACACGCATCAGCACCCAGGCCATATGACTGTGGCCGTTGCGGACTGAAGTTCTTCTTCAGAGCCGAACTCGATAACCACGCGTTCGTTCACCTTGAAGAAGCTGAAATAGCCCAGAGAGCATTCTATGAAGCCTATGCTCGTGGGGCGGCATCGGCATGGGCTGCTTTGCAACCGACAGACCTAGCATCGCAGCCTACGGTATCAACTCCAGCCCCAGTTGATAATGAAGTGACAGTCAAGCGAGAACCAGAAGTTAAAGAAGAACGCAACGATGAATATATTGAAGTGTCATCGCCCCCTCCTCCTCAGCCGCCCCCGCAGCCCGAGCCAGTATCTACTTCTCCGCCGGTAGTGAAAATAGAGAAAACTGACGGAGACTGA
Protein Sequence: MIMLFKGNSSRLEHLIEKIQANKENHDVTTEDLKQALGSVGSVGSVGSTGGSSWPSSTPEPSPSPSSTPTSHDAVDAEADADADPPFTLGATEHTPYKCKFCDKAFPRLSYLKKHEQTHSDQMPFRCEFCSHLFKHKRSRDRHVKLHTGDRKYRCAHCESAFSRSDHLKIHMKTHDNQKPFQCTVCNRGYSTAAALTSHMQGHKREREGRETNRKRALHCLRCGDAFRRPDLLQAHMSSVHGVDGTAMTPPRRVASQPPPTLLACIYCTRDTFTSMEQLQLHVRAAHSALLNGETSVQYTVDQPMPTDLSRRSPENLSPAKRVRLNSGSTTPKTALSPSTLLCNQCDAALPDFEAFRAHLKAHIEEGGELGRTSPAPCLHCGATFADAAASERHLAAHYLAVSCEYTCHSCVRSFPTPEDLQKHLFDMHAHHMYQCNLCKEIFDSKVAIQAHFAMAHSAENKVWVCRSCGSAGGALRTEAEGSAHVRARHAAARCTCGAVLSGSRALRAHAAAHHTFRCPVPTCTESFAVQYLLERHIQTHHAVAHQGANGDIIRAKRTENNNATEGDGASPPCVSGGDGHAPVTSGGDERRRKNGAVALQCAYCGERTRSRAELEAHTRAHSGAGAARHKCLICDEVLPSAGVLAEHKLTHCKVVAGDTCARCRSRLPSEEAFLTHMARHHPALPAPCVICRQTLASEAEARLHARFHLRPNEDEQRCAICLRALSESEAGEGARACSACYARHAAPRPPPSSDHDCRLCRRTLGSPTRLQAHLIEHTFAGIGAFTCYLCSAMFTSAAGLQRHLPEHASAPRPYDCGRCGLKFFFRAELDNHAFVHLEEAEIAQRAFYEAYARGAASAWAALQPTDLASQPTVSTPAPVDNEVTVKREPEVKEERNDEYIEVSSPPPPQPPPQPEPVSTSPPVVKIEKTDGD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00842895;
90% Identity: iTF_00954845;
80% Identity: -