Basic Information

Insect: Pararge aegeria
Gene Symbol: ham
Assembly: GCA_905163445.1
Location: NC:10552971-10609039[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.33 13 6.0 0.0 2 23 248 270 248 270 0.91

2 9 0.00075 0.031 14.3 1.2 1 23 277 300 277 300 0.93

3 9 1.9e-08 7.7e-07 28.8 0.1 1 23 306 329 306 329 0.96

4 9 1.6e-06 6.6e-05 22.7 1.7 1 23 335 357 335 357 0.95

5 9 5.7e-05 0.0023 17.9 6.1 1 23 363 385 363 385 0.99

6 9 0.00012 0.0047 16.9 0.4 2 21 393 412 392 413 0.94

7 9 1.4e-08 5.6e-07 29.3 0.7 1 23 809 831 809 831 0.98

8 9 4.9e-07 2e-05 24.4 1.7 1 23 837 860 837 860 0.97

9 9 5.4e-06 0.00022 21.1 3.3 1 23 866 888 866 888 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.33	13	6.0	0.0	2	23	248	270	248	270	0.91
2	9	0.00075	0.031	14.3	1.2	1	23	277	300	277	300	0.93
3	9	1.9e-08	7.7e-07	28.8	0.1	1	23	306	329	306	329	0.96
4	9	1.6e-06	6.6e-05	22.7	1.7	1	23	335	357	335	357	0.95
5	9	5.7e-05	0.0023	17.9	6.1	1	23	363	385	363	385	0.99
6	9	0.00012	0.0047	16.9	0.4	2	21	393	412	392	413	0.94
7	9	1.4e-08	5.6e-07	29.3	0.7	1	23	809	831	809	831	0.98
8	9	4.9e-07	2e-05	24.4	1.7	1	23	837	860	837	860	0.97
9	9	5.4e-06	0.00022	21.1	3.3	1	23	866	888	866	888	0.98

Sequence Information

Coding Sequence: ATGAAGATGTCCGcGGCAGACAGTCAGGAGTCTGGCAGTCCTCCACCAAGCCCGACAGACTCCGCAGCATCAGAATCCGCTCCCACCTTAGTCCACATCAAGCAAGAGGCGATGGCACCTGGCACTGATATGAAAGAGTACTACAATGCTTTGGACTTCGGCTTAAACGACACATATCTCTCGAGTTACGACTACACGCGCAGCTATCTACCGAGGCCTCTGGATTTACCTAATCAAAGGTTCCTAGAATCGAAAAGTCCAGATAGAAACGAGGAGTTCAATGATGAAAATGAGAAGTCTGAGTTGAGTTTGCCAAGCGAATTAATACTCAAGTCTGGCGGTGTGTTTTGTAGAGCCAACATCTCTTGTGGAACTAAGTATGGACCTTTTAATGGTAAATGGGTCGGGCAGCCTTACGACAGAAGATATGCATGGGCGGTGGTCGGGAAGAACGGCGTTCGAGGCTGGTTGGACGGCAGAGCGGACAAGTCCAACTGGATGAAGTTCGTCAACTCTACGAACTACCCTCACGATGTCAACTTACAACACTTgctccacgctggccaaGTTTACTATAAAGTGACGAGAGACATCCCACCTGGCCAGGAGTTGCTGCTCGGGCCACGAACACCGTTGCCTCTTCAAGATGTCTTCACTCCACCTGGCCGTGAGGGTTCAAGCGTCCACTCTTCCAGCTCACAGCCGTTGACCGAAGACGAAGAGAGAGAGGAAACTGAACCACGTTGCTCCTTTTGTGACGCCCCATATCCTACTATAGatgcGCTAGATCGTCATTTGGTACAAGCGCACGCGCAACCAGCTTCGGCGTTTCACTGCGAGCTTTGCAACCGAGCGTATAGTACACGCGCGCTTCTTCTACGACATCGTGCACTTACCCACACTGATATCAGAAAATACCCCTGCGAGAATTGTCCGAAGGTATTTACCGATCCTTCCAACCTCCAGCGCCACATCCGCGCGCAGCACGTCGGAGCTCGCAGCCACGCGTGCCCCGAGTGTGGCAAGACCTTCGCCACTTCCTCCGGCCTCAAGCAGCACACGCACATCCACTCCAGCGTCAAGCCTTTCCAGTGCAAGGTTTGCTTTAAAGCATACACTCAGTTTTCCAATTTGTGCCGCCACAAACGAATGCATGTGGCATGCAGAGCATTGGTAGAGTGTGGAAAATGTGGACAGTCCTTCACATCTTATGCGTCTCTCACTAAACATAAGAGATTTTGTGACACAGCATCAGCAGCGAACGTTAATCTACGAGGACAATTACCGCAAGGCCTACAACAGATACCATCTTTATCCAACGTCATGAATACACCAAATAATACAAACCCATTCCCGATGTACAGAGGACCAGCGTTGCCTTTACCGTATAACACGTTTGCTCACTATCCAGCATTATTTTCTGCTGCCGCGGCCGCTTGTCCCCCAGAATTCTTAAGTCCACTCCTGTTTAATGTTCAAGGAGCAAGACTAGCTATGGAACGCGATATGGCTATGAATGCTAGTTTAGTCGCAAAACAACAGGAAGGGCGCATGTCAGTTAAAAGTATGGATAGTACAACCTCGCTTGAGGACATGAAGAAAAACATGGACGTCGATATTGAAATGAAGAAGAGGGAAACTGATGTTGAGCGAGTGTCCACACCGCAAAATATATACGTGAAACAATCTCCTCCTTCCGCTGAAGAAGCTTCTTCAAAGCAACGACCTTCGCCTGTCATGCCAATGTCTACATCAATCGCCCCGTTCAGATTTTCAAGGGAGGAAATGAAACGGAACTCTCCATTCAATTTATCAATGAAGTTGTGCAGTGACGAAGCAGGAACAAAATCTGTTTCACCGAGATTGCCAAAAGATTTGTCAAAGACTTTACGCGGAGAAATTGACAACAAATCTGTATATTCTGACGTCGAAGAAGAATCAAGGAAAGAGCAAAGTGATCAACCACTTGATTTATCAGTTACACGGAAGCAAAACGATAAAGAATCCGATATGGAGAACGATGAACATAACTCTGTTCGTAATATATCAGTTAAATCTTACTCTCCCCCTGATAGTCCAGTAGATAGGGAAAGTAAAACTCCTGAAAATGACACAACTGATGTCGATGTGGAAGCAGTAGAACCAAAAAGGGAAGATTCCCCTATGGTATCACCCGCCTTAGCATTTCCGATGCCAGTACATCCCCAGCATAACAACAGTCTCATTGAAGCAATGTACCGCCCACGTTTTCCGCAGTTTCACACGGCTTCTGATTCTCTTTTGAGTTCTTCGCATTCCCCGTACGTGCCGAGcccgtttaattttttatccccACTTCTCGGTACTGACGGCCCGGACAGACAACCAAGCGCGTATGCGAAATTTCGCGAACTGAGCGCGGGTTCGGGAAAACTTCGAGATCGGTACGCGTGCAAGTTCTGCGGAAAAGTATTCCCGCGTAGTGCTAACTTAACTCGACATCTCCGAACCCACACGGGAGAACAGCCTTACAAATGCAAGTACTGTGAGCGTTCGTTCTCAATATCTTCGAACTTGCAGCGTCACGTGCGGAATATACATAATAAGGAGCGGCCGTTTCGGTGTCCCTTATGTGATAGATGTTTCGGACAGCAGACGAATCTTGACCGACATTTGAAGAAACACGAGGCGGAAGGTGGCGACTCTCCGAGTTCCGCTGACACAGAACAGGATGCGTGTTTCGATGATATTCGATCCTTTATGGGTAAAGTTACTTGTTCTCCTGGAGCGGGTTCGCCGTCTGGAACCTCTCCGCATACGCCTCACGCCCCACATCGCCCTTCAGCTTTAGCAATATCCACATAG
Protein Sequence: MKMSAADSQESGSPPPSPTDSAASESAPTLVHIKQEAMAPGTDMKEYYNALDFGLNDTYLSSYDYTRSYLPRPLDLPNQRFLESKSPDRNEEFNDENEKSELSLPSELILKSGGVFCRANISCGTKYGPFNGKWVGQPYDRRYAWAVVGKNGVRGWLDGRADKSNWMKFVNSTNYPHDVNLQHLLHAGQVYYKVTRDIPPGQELLLGPRTPLPLQDVFTPPGREGSSVHSSSSQPLTEDEEREETEPRCSFCDAPYPTIDALDRHLVQAHAQPASAFHCELCNRAYSTRALLLRHRALTHTDIRKYPCENCPKVFTDPSNLQRHIRAQHVGARSHACPECGKTFATSSGLKQHTHIHSSVKPFQCKVCFKAYTQFSNLCRHKRMHVACRALVECGKCGQSFTSYASLTKHKRFCDTASAANVNLRGQLPQGLQQIPSLSNVMNTPNNTNPFPMYRGPALPLPYNTFAHYPALFSAAAAACPPEFLSPLLFNVQGARLAMERDMAMNASLVAKQQEGRMSVKSMDSTTSLEDMKKNMDVDIEMKKRETDVERVSTPQNIYVKQSPPSAEEASSKQRPSPVMPMSTSIAPFRFSREEMKRNSPFNLSMKLCSDEAGTKSVSPRLPKDLSKTLRGEIDNKSVYSDVEEESRKEQSDQPLDLSVTRKQNDKESDMENDEHNSVRNISVKSYSPPDSPVDRESKTPENDTTDVDVEAVEPKREDSPMVSPALAFPMPVHPQHNNSLIEAMYRPRFPQFHTASDSLLSSSHSPYVPSPFNFLSPLLGTDGPDRQPSAYAKFRELSAGSGKLRDRYACKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHNKERPFRCPLCDRCFGQQTNLDRHLKKHEAEGGDSPSSADTEQDACFDDIRSFMGKVTCSPGAGSPSGTSPHTPHAPHRPSALAIST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00943055;
90% Identity: iTF_00205384;
80% Identity: -